COX3

Summary

Gene Symbol: COX3
Description: cytochrome c oxidase III
Alias: COIII, MTCO3, cytochrome c oxidase subunit III
Species: human

Top Publications

  1. ncbi Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina
    Hu Huang
    Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA
    Invest Ophthalmol Vis Sci 45:2489-96. 2004
  2. doi Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia
    W X Tian
    State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
    Avian Pathol 38:161-6. 2009
  3. doi Genetic variability among Schistosoma japonicum isolates from different endemic regions in China revealed by sequences of three mitochondrial DNA genes
    G H Zhao
    College of Veterinary Medicine, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou, Guangdong Province 510642, PR China
    Vet Parasitol 162:67-74. 2009
  4. ncbi Involvement of cytochrome c oxidase subunit III in energy coupling
    S Wu
    Department of Pathology, Medical College of Pennsylvania, Philadelphia 19102, USA
    Biochemistry 34:16298-305. 1995
  5. ncbi Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae
    H Sato
    Department of Physics, Biology and Informatics, Faculty of Science, Yamaguchi University, Yamaguchi, 753 8512, Japan
    Protoplasma 219:51-8. 2002
  6. doi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
  7. ncbi RNA editing has been lost in the mitochondrial cox3 and rps13 mRNAs in Asparagales
    L Lopez
    Dipartimento di Biologia Cellulare, Universita della Calabria, Ponte P Bucci, Cubo 4C, 87030 Arcavacata di Rende, Italy
    Biochimie 89:159-67. 2007
  8. doi Technical report: immunofluorescence and TUNEL staining of celloidin embedded human temporal bone tissues
    Adam Markaryan
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, United States
    Hear Res 241:1-6. 2008
  9. pmc Phylogenetic analysis of mitochondrial substitution rate variation in the angiosperm tribe Sileneae
    Daniel B Sloan
    Department of Plant and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden
    BMC Evol Biol 9:260. 2009
  10. doi Knock-down of the COX3 and COX17 gene expression of cytochrome c oxidase in the unicellular green alga Chlamydomonas reinhardtii
    Claire Remacle
    Department of Life Sciences, Institute of Botany, B22 University of Liege, 4000 Liege, Belgium
    Plant Mol Biol 74:223-33. 2010

Research Grants

  1. HYDROPHOBIC ASSOCIATIONS OF MEMBRANE COMPLEXES
    NEAL ROBINSON; Fiscal Year: 1990
  2. TRANSLATIONAL CONTROL OF YEAST MITOCHONDRIAL GENES
    Thomas Fox; Fiscal Year: 2001
  3. The Impact of HLA in Children Receiving HAART
    Akihiko Saitoh; Fiscal Year: 2007
  4. mt-Nd2 and Resistance to Autoimmune Diabetes
    Clayton Mathews; Fiscal Year: 2007

Scientific Experts

Detail Information

Publications119 found, 100 shown here

  1. ncbi Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina
    Hu Huang
    Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA
    Invest Ophthalmol Vis Sci 45:2489-96. 2004
    ..In this study, the objective was to study the mechanisms of neuroprotection in the bright cyclic light-reared retina by identification of differentially expressed genes with differential display (DD)-PCR...
  2. doi Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia
    W X Tian
    State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
    Avian Pathol 38:161-6. 2009
    ..pro-alpha-1 collagen type I (Col I alpha1), collagen type IX (Col IX), NADH dehydrogenase (NADH DH), cytochrome C oxidase subunit III (COX III), enolase 1, alpha (ENO1), carbonic anhydrase II (CA2) and heat shock protein 90 (Hsp90) ..
  3. doi Genetic variability among Schistosoma japonicum isolates from different endemic regions in China revealed by sequences of three mitochondrial DNA genes
    G H Zhao
    College of Veterinary Medicine, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou, Guangdong Province 510642, PR China
    Vet Parasitol 162:67-74. 2009
    ..examined sequence variation in three mitochondrial DNA (mtDNA) regions, namely cytochrome c oxidase subunit 3 (cox3), NADH dehydrogenase subunits 4 and 5 (nad4 and nad5), among Schistosoma japonicum isolates from different endemic ..
  4. ncbi Involvement of cytochrome c oxidase subunit III in energy coupling
    S Wu
    Department of Pathology, Medical College of Pennsylvania, Philadelphia 19102, USA
    Biochemistry 34:16298-305. 1995
    The role of the conserved acidic residues of subunit III of cytochrome c oxidase (COIII) in energy transduction was investigated...
  5. ncbi Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae
    H Sato
    Department of Physics, Biology and Informatics, Faculty of Science, Yamaguchi University, Yamaguchi, 753 8512, Japan
    Protoplasma 219:51-8. 2002
    ..In contrast, porin and cytochrome c oxidase subunit III (CoxIIIp) were not detected by immunoblotting in the mt-nucleoid fraction...
  6. doi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
    ..in the form of a circular and/or tandemly repeated linear element of 6 kb, encoding only three protein genes (cox1, cox3, and cob). The closely related genera Babesia and Theileria also have small mt genomes (6...
  7. ncbi RNA editing has been lost in the mitochondrial cox3 and rps13 mRNAs in Asparagales
    L Lopez
    Dipartimento di Biologia Cellulare, Universita della Calabria, Ponte P Bucci, Cubo 4C, 87030 Arcavacata di Rende, Italy
    Biochimie 89:159-67. 2007
    ..for RNA editing in the complete genomic sequences of the gene encoding the cytochrome oxidase subunit III (cox3) and the ribosomal protein S13 (rps13) in 59 closely related species within the Asparagales and Liliales (monocots)...
  8. doi Technical report: immunofluorescence and TUNEL staining of celloidin embedded human temporal bone tissues
    Adam Markaryan
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, United States
    Hear Res 241:1-6. 2008
    ..knowledge, successful immunofluorescence staining of type I collagen, immunofluorescence staining of cytochrome c oxidase subunit III (COX III), and TUNEL staining in archival human temporal bone tissues with confocal microscopy has ..
  9. pmc Phylogenetic analysis of mitochondrial substitution rate variation in the angiosperm tribe Sileneae
    Daniel B Sloan
    Department of Plant and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden
    BMC Evol Biol 9:260. 2009
    ..noctiflora is a recent and isolated evolutionary event. This assessment, however, is based on a very limited sampling of taxa within this diverse genus...
  10. doi Knock-down of the COX3 and COX17 gene expression of cytochrome c oxidase in the unicellular green alga Chlamydomonas reinhardtii
    Claire Remacle
    Department of Life Sciences, Institute of Botany, B22 University of Liege, 4000 Liege, Belgium
    Plant Mol Biol 74:223-33. 2010
    The COX3 gene encodes a core subunit of mitochondrial cytochrome c oxidase (complex IV) whereas the COX17 gene encodes a chaperone delivering copper to the enzyme...
  11. ncbi The analysis of the complete mitochondrial genome of Lecanicillium muscarium (synonym Verticillium lecanii) suggests a minimum common gene organization in mtDNAs of Sordariomycetes: phylogenetic implications
    Vassili N Kouvelis
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistemiopolis, Athens 157 01, Greece
    Fungal Genet Biol 41:930-40. 2004
    ..mtDNA gene order could be detected, in two units, for all known Sordariomycetes namely nad1-nad4-atp8-atp6 and rns-cox3-rnl, which can be extended in Hypocreales, to nad4L-nad5-cob-cox1-nad1-nad4-atp8-atp6 and rns-cox3-rnl nad2-nad3, ..
  12. ncbi The highly reduced and fragmented mitochondrial genome of the early-branching dinoflagellate Oxyrrhis marina shares characteristics with both apicomplexan and dinoflagellate mitochondrial genomes
    Claudio H Slamovits
    Department of Botany, University of British Columbia, Vancouver, BC, Canada
    J Mol Biol 372:356-68. 2007
    ..the smallest gene complement known, with several rRNA fragments and only two protein coding genes, cox1 and a cob-cox3 fusion...
  13. ncbi Differential expression of cytochrome c oxidase subunit III gene in castes of the termite Reticulitermes santonensis
    Marjorie A Liénard
    Department of Ecology, Lund University, Solvegatan 37, SE 223 62 Lund, Sweden
    J Insect Physiol 52:551-7. 2006
    ..We used the cytochrome c oxidase subunit III gene (COXIII) that was cloned from mRNA in a lower termite, Reticulitermes santonensis De Feytaud (..
  14. ncbi The complete DNA sequence of the mitochondrial genome of the dermatophyte fungus Epidermophyton floccosum
    José Humberto M Tambor
    Instituto de Ciencias Biomedicas, Departamento de Microbiologia, Universidade de Sao Paulo, Av Prof Lineu Prestes, 1374, Ed Biomédicas II, Cidade Universitaria, CEP 05508 900, Sao Paulo, Brazil
    Curr Genet 49:302-8. 2006
    ..oxireductase (nad1, nad2, nad3, nad4, nad4L, nad5, and nad6), three subunits of cytochrome oxidase (cox1, cox2, and cox3), apocytochrome b (cob), three subunits of ATP synthase (atp6, atp8, and atp9), the small and large ribosomal RNAs (..
  15. pmc Rpm2, the protein subunit of mitochondrial RNase P in Saccharomyces cerevisiae, also has a role in the translation of mitochondrially encoded subunits of cytochrome c oxidase
    V Stribinskis
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Louisville, Louisville, KY 40292, USA
    Genetics 158:573-85. 2001
    ..Pulse-chase analysis of mitochondrial translation revealed decreased rates of translation of COX1, COX2, and COX3 mRNAs...
  16. ncbi Group-I introns in the cytochrome c oxidase genes of Dictyostelium discoideum: two related ORFs in one loop of a group-I intron, a cox1/2 hybrid gene and an unusually large cox3 gene
    S Ogawa
    Institute of Biological Sciences, University of Tsukuba, Tsukuba, Ibaraki 305, Japan
    Curr Genet 31:80-8. 1997
    ..4) also have a free-standing ORF in loop 1 and loop 2, respectively. These results show that these group-I introns and the intronic ORFs have evolved from the same ancestral origin, but that these ORFs have been propagated independently...
  17. doi The mitochondrial genome of a deep-sea bamboo coral (Cnidaria, Anthozoa, Octocorallia, Isididae): genome structure and putative origins of replication are not conserved among octocorals
    Mercer R Brugler
    Department of Biology, University of Louisiana at Lafayette, P O Box 42451, Lafayette, LA 70504, USA
    J Mol Evol 67:125-36. 2008
    ..octocoral mt genome, which has 12 genes transcribed on one strand and 5 genes on the opposite (cox2, atp8, atp6, cox3, trnM), in the bamboo coral genome a contiguous string of 5 genes (msh1, rnl, nad2, nad5, nad4) has undergone an ..
  18. doi Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy
    M Sievers
    Department of Rheumatology and Clinical Immunology, Medizinische Universitatsklinik, Freiburg, Germany
    J Infect Dis 200:252-62. 2009
    ..Long-term use of both zidovudine (AZT) and stavudine (d4T) is associated with lipoatrophy, but it occurs possibly through different mechanisms...
  19. ncbi The mitochondrial genome of Acropora tenuis (Cnidaria; Scleractinia) contains a large group I intron and a candidate control region
    Madeleine J H van Oppen
    Biochemistry and Molecular Biology, James Cook University, Townsville, Queensland 4811, Australia
    J Mol Evol 55:1-13. 2002
    ..Finally, we provide evidence that the rns-cox3 intergenic region in A. tenuis may correspond to the mitochondrial control region of higher animals...
  20. ncbi The complete mitochondrial genome of the yeast Kluyveromyces thermotolerans
    Emmanuel Talla
    Unité de Génétique Moléculaire des Levures URA 2171 CNRS, UFR 927 Université PM Curie, Institut Pasteur, 25 rue du Docteur Roux, F 75724 Paris Cedex 15, France
    FEBS Lett 579:30-40. 2005
    ..It encodes, all on the same DNA strand, three subunits of cytochrome oxidase (COX1, COX2 and COX3), three subunits of ATP synthetase (ATP6, ATP8 and ATP9), the apocytochrome b (COB), the ribosomal protein VAR1, 24 ..
  21. pmc A genetic link between an mRNA-specific translational activator and the translation system in yeast mitochondria
    P Haffter
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Genetics 125:495-503. 1990
    Translation of the Saccharomyces cerevisiae mitochondrial mRNA encoding cytochrome c oxidase subunit III (coxIII) specifically requires the products of at least three nuclear genes, PET122, PET494 and PET54...
  22. pmc Functional interactions among two yeast mitochondrial ribosomal proteins and an mRNA-specific translational activator
    P Haffter
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Genetics 127:319-26. 1991
    Expression of the Saccharomyces cerevisiae mitochondrial gene coding cytochrome c oxidase subunit III is specifically activated at the level of translation by at least three nuclear genes, PET122, PET494 and PET54...
  23. pmc A novel small-subunit ribosomal protein of yeast mitochondria that interacts functionally with an mRNA-specific translational activator
    T W McMullin
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Mol Cell Biol 10:4590-5. 1990
    Mitochondrial translation of the mRNA encoding cytochrome c oxidase subunit III (coxIII) specifically requires the action of three position activator proteins encoded in the nucleus of Saccharomyces cerevisiae...
  24. pmc Specific translational activation by nuclear gene products occurs in the 5' untranslated leader of a yeast mitochondrial mRNA
    M C Costanzo
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853
    Proc Natl Acad Sci U S A 85:2677-81. 1988
    Translation of the yeast mitochondrial mRNA encoding cytochrome c oxidase subunit III (coxIII) is specifically activated by the products of at least three nuclear genes, PET494, PET54, and PET122...
  25. ncbi Making the most of mitochondrial genomes--markers for phylogeny, molecular ecology and barcodes in Schistosoma (Platyhelminthes: Digenea)
    M Z Zarowiecki
    Wolfson Wellcome Biomedical Laboratories, Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
    Int J Parasitol 37:1401-18. 2007
    ..mansoni. The genes nad1, nad4, nad5, cox1 and cox3 resolved phylogenies that were consistent with a benchmark phylogeny and in general, longer genes performed better ..
  26. doi Molecular evolution of cytochrome C oxidase underlies high-altitude adaptation in the bar-headed goose
    Graham R Scott
    Department of Zoology, University of British Columbia, Vancouver, BC, Canada
    Mol Biol Evol 28:351-63. 2011
    ..However, the COX3 gene of bar-headed geese contained a nonsynonymous substitution at a site that is otherwise conserved across ..
  27. ncbi Screening of phage displayed human liver cDNA library against dexamethasone
    Xiaoming Yu
    National Chromatographic Research and Analysis Center, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023, PR China
    J Pharm Biomed Anal 45:701-5. 2007
    ..phages with the lengths of 400 and 600 bp were sequenced, and revealed identical sequences with cytochrome c oxidase subunit III and albumin respectively by GenBank searching...
  28. pmc Two distinct, sequence-specific DNA-binding proteins interact independently with the major replication pause region of sea urchin mtDNA
    S A Qureshi
    Robertson Institute of Biotechnology, Department of Genetics, University of Glasgow, UK
    Nucleic Acids Res 21:2801-8. 1993
    ..in the major replication pause region, at the junction of the genes for ATP synthase subunit 6 and cytochrome c oxidase subunit III (COIII)...
  29. doi The PPR protein encoded by the LOVASTATIN INSENSITIVE 1 gene is involved in RNA editing at three sites in mitochondria of Arabidopsis thaliana
    Daniil Verbitskiy
    Molekulare Botanik, Universitat Ulm, 89069 Ulm, Germany
    Plant J 61:446-55. 2010
    ..Here we identify the nuclear-encoded gene MEF11, which is involved in RNA editing of the three sites cox3-422, nad4-124 and ccb203-344 in Arabidopsis thaliana...
  30. pmc Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity
    Torsten Ochsenreiter
    Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
    PLoS ONE 3:e1566. 2008
    ..Recently, it has been shown that cytochrome c oxidase subunit III (COXIII) mRNAs can be alternatively edited to encode a novel mitochondrial membrane protein composed ..
  31. doi Age-dependent down-regulation of mitochondrial 8-oxoguanine DNA glycosylase in SAM-P/8 mouse brain and its effect on brain aging
    Feng Tian
    Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Peking University Research Center on Aging, Beijing, China
    Rejuvenation Res 12:209-15. 2009
    ..and protein levels of OGG1, especially OGG1 targeting to mitochondria, and the expression level of cytochrome c oxidase subunit III (COX III) in the brain of both SAM-P/8 mice and SAM-R/1 mice, decreased with age...
  32. doi Mitochondrial genome polymorphisms associated with longissimus muscle composition in Iberian pigs
    A I Fernandez
    Departamento de Mejora Genética Animal, INIA, Ctra de La Coruña Km 7 5, 28040 Madrid, Spain
    J Anim Sci 86:1283-90. 2008
    ..detected in H3 carriers: a synonymous transition 9104C > T in the gene-coding region of Cytochrome c oxidase subunit III and a substitution 715A > G in 12S rRNA...
  33. pmc Mitochondrial sequence data expose the putative cosmopolitan polychaete Scoloplos armiger (Annelida, Orbiniidae) as a species complex
    Christoph Bleidorn
    Animal Systematics and Evolution, Institute for Biology, Zoology, Free University Berlin, Koenigin Luise Str, 1 3, D 14195 Berlin, Germany
    BMC Evol Biol 6:47. 2006
    ..armiger mitochondrial genome and developed primers for variable regions including the 3' end of the cox3 gene, trnQ, and most of nad6. A phylogenetic analysis of this 528-nucleotide fragment was carried out for S...
  34. pmc Homogeneous population of the brown alga Sargassum polycystum in Southeast Asia: possible role of recent expansion and asexual propagation
    Sze Wai Chan
    Marine Science Laboratory, Chinese University of Hong Kong, N T, Hong Kong SAR, China
    PLoS ONE 8:e77662. 2013
    ..Spacer 2 (ITS2), plastidal RuBisCO spacer (Rub spacer) and mitochondrial cytochrome oxidase subunit-III (Cox3) as molecular markers revealed genetic homogeneity across 27 sites in Southeast Asia and western Pacific, in sharp ..
  35. doi Cytochrome c oxidase subunit III (COX3) gene, an informative marker for phylogenetic analysis and differentiation of Babesia species in China
    Zhancheng Tian
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China
    Infect Genet Evol 18:13-7. 2013
    In this study a 552-bp region of the cytochrome c oxidase subunit III (COX3) was amplified by polymerase chain reaction (PCR) and sequenced from individual Babesia species...
  36. pmc Antagonistic signals within the COX2 mRNA coding sequence control its translation in Saccharomyces cerevisiae mitochondria
    Elizabeth H Williams
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853 2703, USA
    RNA 9:419-31. 2003
    ..leader sequences, as they are also observed when the same reporter constructs are expressed from the COX3 locus...
  37. doi Aluminium induced oxidative stress results in decreased mitochondrial biogenesis via modulation of PGC-1α expression
    Deep Raj Sharma
    Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Toxicol Appl Pharmacol 273:365-80. 2013
    ..e. ND1, ND2, ND3, Cytochrome b (Cytb), Cytochrome oxidase (COX) subunits i.e. COX1, COX3, ATP synthase (ATPase) subunit 6 along with reduced expression of nuclear encoded subunits COX4, COX5A, COX5B of ..
  38. doi The complete mitochondrial genomes of deep-sea squid (Bathyteuthis abyssicola), bob-tail squid (Semirossia patagonica) and four giant cuttlefish (Sepia apama, S. latimanus, S. lycidas and S. pharaonis), and their application to the phylogenetic analysis o
    Yuumi Kawashima
    Central Customs Laboratory, 6 3 5, Kashiwanoha, Kashiwa shi, Chiba 277 0082, Japan
    Mol Phylogenet Evol 69:980-93. 2013
    ..that include seven genes (COX1-3, ATP6 and ATP8, tRNA(Asn), and either ND2 or ND3) and that one of the duplicated COX3 genes has lost its function. The mt genome of S...
  39. pmc Low genetic diversity in wide-spread Eurasian liver fluke Opisthorchis felineus suggests special demographic history of this trematode species
    Ilja I Brusentsov
    Laboratory of Molecular Mechanisms of Pathological Processes, Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia
    PLoS ONE 8:e62453. 2013
    ..Analysis of marker DNA fragments from O. felineus mitochondrial cytochrome c oxidase subunit 1 and 3 (cox1, cox3) and nuclear rDNA internal transcribed spacer 1 (ITS1) sequences revealed that genetic diversity is very low across ..
  40. doi Complete mitochondrial genome of the Xiangjiang barbel chub Squaliobarbus curriculus: comparative analysis of the genetic variation associated with geographical population
    Qiao Lin Liu
    College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, People s Republic of China
    Mitochondrial DNA 24:654-6. 2013
    ..the 21 mutation sites in protein-coding genes, 6 mutation sites resulted in amino acid mutation in ND2, ATPase6, COX3, ND4, and Cytb genes, while the others were synonymous substitutions...
  41. ncbi Quantitative change in mitochondrial DNA content in various mouse tissues during aging
    Mika Masuyama
    Department of Forensic Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka cho, Fukui 910 1193, Japan
    Biochim Biophys Acta 1723:302-8. 2005
    ..The Western blot analysis of mtDNA-encoded cytochrome c oxidase subunit III (MTCO3) demonstrated that the expression levels of this protein in the heart and skeletal muscle ..
  42. doi Screening of mitochondrial mutations in Tunisian patients with mitochondrial disorders: an overview study
    Emna Mkaouar-Rebai
    Human Molecular Genetic Laboratory, Faculty of Medicine of Sfax, Avenue Magida Boulila, 3029 Sfax, Tunisia
    Mitochondrial DNA 24:163-78. 2013
    ..9478T>C mutation in the cytochrome c oxidase subunit III (COXIII) gene were found with LS...
  43. pmc The mitochondrial genome of the venomous cone snail Conus consors
    Age Brauer
    Estonian Biocentre, Tartu, Estonia
    PLoS ONE 7:e51528. 2012
    ..and is located between the genes encoding the transfer RNA for phenylalanine (tRNA-Phe, trnF) and cytochrome c oxidase subunit III (cox3)...
  44. pmc Microsatellite repeat dynamics in mitochondrial genomes of phytopathogenic fungi: frequency and distribution in the genic and intergenic regions
    Sahil Mahfooz
    Department of Biotechnology and Bioinformatics, Barkatullah University, Bhopal 462 026, Madhya Pradesh, India
    Bioinformation 8:1171-5. 2012
    ..Among the genes, cox1 harbors the maximum SSRs, whereas cox3 and nad 7 contain the least...
  45. pmc Empty pericarp5 encodes a pentatricopeptide repeat protein that is required for mitochondrial RNA editing and seed development in maize
    Yu Jun Liu
    State Key Lab of Agrobiotechnology, Institute of Plant Molecular Biology and Agrobiotechnology, School of Life Science, Chinese University of Hong Kong, Shatin, N T, Hong Kong, China
    Plant Cell 25:868-83. 2013
    ..edited in the wild type), decreases the editing at nine sites in NADH dehydrogenase9 (nad9), cytochrome c oxidase3 (cox3), and ribosomal protein S12 (rps12), and surprisingly increases the editing at five sites of ATP synthase F0 ..
  46. doi Gene expression profile of hepatopancreas from grass shrimp Palaemonetes pugio exposed to cyclic hypoxia
    Tiandao Li
    Department of Coastal Sciences, University of Southern Mississippi, Ocean Springs, MS 39564, USA
    Comp Biochem Physiol Part D Genomics Proteomics 8:1-10. 2013
    ..Vitellogenin, cathepsin L, cytochrome c oxidase subunit III, and fatty acid binding protein 10 were the signature down-regulated genes at day 10 (C-AM)...
  47. pmc Biogenesis and assembly of eukaryotic cytochrome c oxidase catalytic core
    Ileana C Soto
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Biochim Biophys Acta 1817:883-97. 2012
    ..The COX catalytic core is formed by three mitochondrial DNA encoded subunits, Cox1, Cox2 and Cox3, conserved in the bacterial enzyme...
  48. doi The complete mitochondrial genome sequence of Eimeria mitis (Apicomplexa: Coccidia)
    Guo hua Liu
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, P R China
    Mitochondrial DNA 23:341-3. 2012
    ..The complete mt genome sequence of E. mitis is 6407 bp in size. It consists of 3 protein-coding genes (cox1, cox3, and cytb), 12 gene fragments for the large subunit (LSU) rRNA, and 7 gene fragments for the small subunit (SSU) ..
  49. doi Domestication and geographic origin of Oryza sativa in China: insights from multilocus analysis of nucleotide variation of O. sativa and O. rufipogon
    Xin Wei
    College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, China
    Mol Ecol 21:5073-87. 2012
    ..sativa in China through sequence analyses of six gene regions, trnC-ycf6 in chloroplast genomes, cox3 in mitochondrial genomes and ITS, Ehd1, Waxy, Hd1 in nuclear genomes...
  50. pmc Nuclear outsourcing of RNA interference components to human mitochondria
    Simonetta Bandiera
    INSERM U781 Hôpital Necker Enfants Malades, Paris, France
    PLoS ONE 6:e20746. 2011
    ..and confocal microscopy, and further validated by the co-immunoprecipitation of the mitochondrial transcript COX3. This study provides the first comprehensive view of the localization of RNA interference components to the ..
  51. doi The mitochondrial genome of Gyrodactylus derjavinoides (Platyhelminthes: Monogenea)--a mitogenomic approach for Gyrodactylus species and strain identification
    Tine Huyse
    Laboratory of Animal Diversity and Systematics, Catholic University of Leuven, Ch Deberiotstraat 32, B3000 Leuven, Belgium
    Gene 417:27-34. 2008
    ..In total, 6 new primer pairs have been developed, amplifying fragments of cox1, cox3, nad1, nad2, nad4, nad5 and atp6...
  52. pmc A shared RNA-binding site in the Pet54 protein is required for translational activation and group I intron splicing in yeast mitochondria
    Benjamin J Kaspar
    Center for RNA Molecular Biology, Case Western Reserve University, School of Medicine, Cleveland, OH 44106 4960, USA
    Nucleic Acids Res 36:2958-68. 2008
    ..example of a dual functioning ('moonlighting') protein: it is required for translational activation of the COX3 mRNA and splicing of the aI5beta group I intron in the COX1 pre-mRNA in Saccharomyces cerevisiae mitochondria (mt)...
  53. doi The complete mitochondrial genome of the grand jackknife clam, Solen grandis (Bivalvia: Solenidae): a novel gene order and unusual non-coding region
    Yang Yuan
    Fisheries College, Ocean University of China, Qingdao, China
    Mol Biol Rep 39:1287-92. 2012
    ..In contrast to the available heterodont mitochondrial genomes from GenBank, the complete mtDNA of S. grandis has the shortest cox3 gene, and the longest atp6, nad4, nad5 genes.
  54. pmc Plant-type mitochondrial RNA editing in the protist Naegleria gruberi
    Mareike Rüdinger
    Department of Molecular Evolution, IZMB, University of Bonn, Bonn, Germany
    RNA 17:2058-62. 2011
    ..Naegleria gruberi and here report on identification of two sites of C-to-U RNA editing in the cox1 gene and in the cox3 gene, both of which reconstitute amino acid codon identities highly conserved in evolution. An estimated 1...
  55. doi Genetic diversity of liver flukes (Fasciola hepatica) from Eastern Europe
    D Teofanova
    Institute of Experimental Pathology and Parasitology BAS, 25 Akad Georgi Bonchev, 1113 Sofia, Bulgaria
    Infect Genet Evol 11:109-15. 2011
    ..lineages and additional haplotypes were defined for the mtDNA gene region which consisted of the cytochrome c oxidase subunit III gene, transfer RNA histidine gene and cytochome b gene...
  56. ncbi Analysis of the complete mitochondrial genome sequences of the soybean rust pathogens phakopsora pachyrhizi and p. meibomiae
    Christine L Stone
    USDA Agricultural Research Service, Foreign DiseaseWeed Science Research Unit, 1301 Ditto Avenue, Fort Detrick, Maryland 21702, USA
    Mycologia 102:887-97. 2010
    ..ATP synthase subunits 6, 8 and 9 (atp6, atp8 and atp9), cytochrome oxidase subunits I, II and III (cox1, cox2 and cox3), apocytochrome b (cob), reduced nicotinamide adenine dinucleotide ubiquinone oxidoreductase subunits (nad1, nad2, ..
  57. doi What limits the allotopic expression of nucleus-encoded mitochondrial genes? The case of the chimeric Cox3 and Atp6 genes
    Francisco Figueroa-Martínez
    Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    Mitochondrion 11:147-54. 2011
    ..Some OXPHOS proteins like ATP6 (subunit a of complex V) and COX3 (subunit III of complex IV) that are typically mtDNA-encoded, are naturally nucleus-encoded in the alga ..
  58. doi Genetic diversity of Ectocarpus (Ectocarpales, Phaeophyceae) in Peru and northern Chile, the area of origin of the genome-sequenced strain
    Akira F Peters
    Marine Biological Association, Citadel Hill, Plymouth PL1 2PB, UK
    New Phytol 188:30-41. 2010
    ..from four nuclear and cytoplasmic genetic markers (ITS1, ITS2, Rubisco spacer and Cytochrome-c oxidase subunit 3 (cox3)) separated the genome strain from the known species of Ectocarpus...
  59. doi Targeted gene disruption identifies three PPR-DYW proteins involved in RNA editing for five editing sites of the moss mitochondrial transcripts
    Shotaro Ohtani
    Center for Gene Research, Nagoya University, Chikusa ku, Nagoya 464 8602, Japan
    Plant Cell Physiol 51:1942-9. 2010
    ..revealed that PpPPR_56 was involved in RNA editing at the nad3 and nad4 sites, PpPPR_77 at the cox2 and cox3 sites, and PpPPR_91 at the nad5-2 site in the mitochondrial transcripts...
  60. doi Phylogeographic heterogeneity of the brown macroalga Sargassum horneri (Fucaceae) in the northwestern Pacific in relation to late Pleistocene glaciation and tectonic configurations
    Zi Min Hu
    Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
    Mol Ecol 20:3894-909. 2011
    ..phylogeographic profiles of littoral macroalga Sargassum horneri in the ANP were analysed based on mitochondrial (Cox3) and chloroplast (rbcL) data sets. Five distinct clades were recovered...
  61. pmc The complete mitochondrial genome of the bag-shelter moth Ochrogaster lunifer (Lepidoptera, Notodontidae)
    Paola Salvato
    Department of Public Health, Comparative Pathology and Veterinary Hygiene, University of Padova, Agripolis, Viale dell Universita 16, 35020 Legnaro, Italy
    BMC Genomics 9:331. 2008
    ..Thus advance of lepidopteran mitogenomics deeply requires new genomes derived from a broad taxon sampling. In present work we describe the mitochondrial genome of the moth Ochrogaster lunifer...
  62. ncbi The complete mitochondrial genome sequence of Geisha distinctissima (Hemiptera: Flatidae) and comparison with other hemipteran insects
    Nan Song
    Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
    Acta Biochim Biophys Sin (Shanghai) 41:206-16. 2009
    ..TAA and TAG termination codons are found in nine protein-coding genes, and the remaining four (cox1, atp6, cox3, and nad4) have incomplete termination codons...
  63. doi Validation of RT-qPCR reference genes for in planta expression studies in Hemileia vastatrix, the causal agent of coffee leaf rust
    Ana Vieira
    Centro de Investigação das Ferrugens do Cafeeiro Instituto de Investigação Científica Tropical, Oeiras, Portugal
    Fungal Biol 115:891-901. 2011
    ..dehydrogenase (GADPH), elongation factor (EF-1), Beta tubulin (β-tubulin), cytochrome c oxidase subunit III (Cyt III), cytochrome b (Cyt b), Hv00099, and 40S ribosomal protein (40S_Rib)] were analysed across ..
  64. doi Major arc mitochondrial DNA deletions in cytochrome c oxidase-deficient human cochlear spiral ganglion cells
    Adam Markaryan
    Department of Surgery, University of Chicago, IL, USA
    Acta Otolaryngol 130:780-7. 2010
    ..In addition to the mitochondrial DNA (mtDNA) common deletion (CD), other deletions involving the mtDNA major arc contribute to the observed deficit in COX 3 expression...
  65. doi The mitochondrial PPR protein LOVASTATIN INSENSITIVE 1 plays regulatory roles in cytosolic and plastidial isoprenoid biosynthesis through RNA editing
    Jianwei Tang
    RIKEN Plant Science Center, 1 7 22, Suehiro cho, Tsurumi ku, Yokohama, Kanagawa 230 0045, Japan
    Plant J 61:456-66. 2010
    ..of analysis of RNA editing of mitochondrial genes in loi1, a defect in RNA editing of three genes, nad4, ccb203 and cox3, was identified in loi1. These genes are related to the respiratory chain...
  66. ncbi Permethrin induces overexpression of multiple genes in Aedes aegypti
    Julia W Pridgeon
    Center for Medical, Agricultural, and Veterinary Entomology, USDA ARS, 1600 SW, 23rd Dr, Gainesville, FL 32608, USA
    J Med Entomol 46:580-7. 2009
    ..aegypti. These eight genes include three functionally known genes (cytochrome c oxidase subunit III, NADH2 dehydrogenase, deltamethrin resistance associated protein), three functionally unknown genes (..
  67. doi A molecular phylogeny of bryozoans
    Andrea Waeschenbach
    Department of Zoology, The Natural History Museum, Cromwell Road, London SW7 5BD, UK
    Mol Phylogenet Evol 62:718-35. 2012
    ..generated during this project are for each gene:ssrDNA (32), lsrDNA (22), rrnL (38), rrnS (35), cox1 (37), cox3 (34), and cytb (44). Our multi-gene analysis provides a largely stable topology across the phylum...
  68. pmc Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells
    Akihiko Saitoh
    Division of Infectious Diseases, Department of Pediatrics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0672, USA
    Antimicrob Agents Chemother 52:2825-30. 2008
    ..001). Regardless of the NRTI regimens examined, NRTI combinations significantly decreased mtRNA (MTCO3) in myoblasts and myotubes (P = 0.02 and P = 0.01, respectively)...
  69. ncbi Contrasting signatures of population growth for mitochondrial DNA and Y chromosomes among human populations in Africa
    Maya Metni Pilkington
    Department of Anthropology, University of Arizona, USA
    Mol Biol Evol 25:517-25. 2008
    ..6 kb of noncoding Y chromosomal DNA and 780 basepairs of the mtDNA cytochrome c oxidase subunit III (COIII) gene in 172 males from 5 African populations...
  70. ncbi Suppression of carboxy-terminal truncations of the yeast mitochondrial mRNA-specific translational activator PET122 by mutations in two new genes, MRP17 and PET127
    P Haffter
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853 2703
    Mol Gen Genet 235:64-73. 1992
    ..cerevisiae nuclear gene products required specifically to activate translation of the mitochondrially coded COX3 mRNA...
  71. ncbi Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
    R M Andrews
    Nat Genet 23:147. 1999
  72. ncbi Use of atp6 in fungal phylogenetics: an example from the boletales
    A M Kretzer
    Department of Plant and Microbial Biology, University of California at Berkeley, 111 Koshland Hall, Berkeley, California, 94720 3102, USA
    Mol Phylogenet Evol 13:483-92. 1999
    Complete nucleotide sequences have been determined for atp6 from Suillus luteus and cox3 from Suillus sinuspaulianus (Boletales, Hymenomycetes, Basidiomycota), which code for ATPase subunit 6 and cytochrome oxidase subunit 3, respectively...
  73. ncbi Cloning and characterization of COX18, a Saccharomyces cerevisiae PET gene required for the assembly of cytochrome oxidase
    R L Souza
    Departamento de Microbiologia, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Av Prof Lineu Prestes, 1374, 05508 900, Sao Paulo, SP, Brazil
    J Biol Chem 275:14898-902. 2000
    ..Transcription of COX2 does not require COX18 function, and a chimeric COX3-COX2 mRNA did not suppress the respiratory defect in the null mutant, indicating that the mutation does not impair ..
  74. ncbi Men with oligoasthenoteratozoospermia harbour higher numbers of multiple mitochondrial DNA deletions in their spermatozoa, but individual deletions are not indicative of overall aetiology
    J C St John
    Assisted Conception Unit, Birmingham Women s Hospital, Birmingham B15 2TG, UK
    Mol Hum Reprod 7:103-11. 2001
    ..We further analysed the incidence of one other deletion, the 15 bp deletion in the cytochrome c oxidase subunit III (COX III) of complex IV to determine whether other deletions flanked by direct repeats could be ..
  75. pmc A comparison of three fission yeast mitochondrial genomes
    C E Bullerwell
    Program in Evolutionary Biology, Canadian Institute for Advanced Research, Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada
    Nucleic Acids Res 31:759-68. 2003
    ..mitochondrial small subunit ribosomal protein 3 (rps3), cytochrome oxidase subunits 1, 2 and 3 (cox1, cox2 and cox3) and ATP-synthase subunits 6, 8 and 9 (atp6, atp8 and atp9)...
  76. ncbi Cloning and sequence analysis of a mitochondrial gene cluster encoding cytochrome C oxidase subunit III from Trichoderma pseudokoningii
    Tian Hong Wang
    State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, Shandong, People s Republic of China
    DNA Seq 13:271-5. 2002
    A mitochondrial gene cluster encoding cytochrome c oxidase subunit III (COX3), an ORF (called ORF250) similar to NADH dehydrogenase subunit VI (ND6), ten tRNA molecules, partial rRNA small subunit and rRNA large subunit from Trichoderma ..
  77. ncbi Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster
    Aner Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, Austria
    FEMS Yeast Res 2:123-35. 2002
    ..DAPI staining for DNA in combination with Southern analysis using the mitochondrial genes COX3, 15S_rRNA_2, and COB revealed that a significant portion of the surviving meiotic progeny were [rho(0)] lacking ..
  78. pmc Sequence analysis of three mitochondrial DNA molecules reveals interesting differences among Saccharomyces yeasts
    R B Langkjaer
    BioCentrum DTU, Technical University of Denmark, Building 301, DK 2800 Kgl Lyngby, Denmark
    Nucleic Acids Res 31:3081-91. 2003
    ..cerevisiae mtDNA, are not present. Surprisingly, four genes (ATP6, COX2, COX3 and COB) in the mtDNA of S.servazzii contain, in total, five +1 frameshifts. mtDNAs of S.castellii, S...
  79. ncbi Mutant and wild-type alpha-synuclein interact with mitochondrial cytochrome C oxidase
    Hanock Elkon
    Felsenstein Medical Research Center, Department of Clinical Biochemistry, Sackler School of Medicine, Tel Aviv University, Petah Tikva, Israel
    J Mol Neurosci 18:229-38. 2002
    ..This interaction suggests that alpha-synuclein aggregation may contribute to enhance the mitochondrial dysfunction, which might be a key factor in the pathogenesis of PD...
  80. ncbi Partial kinetoplast-mitochondrial gene organization and expression in the respiratory deficient plant trypanosomatid Phytomonas serpens
    D A Maslov
    Department of Biology, University of California, Riverside 92521, USA
    Mol Biochem Parasitol 99:207-21. 1999
    ..A deletion of the genes for cytochrome c oxidase subunit III (COIII) and apocytochrome b (Cyb) was identified within the 6234 bp sequenced region of the 31 kb ..
  81. ncbi Complex II subunit 4 (sdh4) homologous sequences in plant mitochondrial genomes
    P Giegé
    Allgemeine Botanik, Universitat Ulm, Albert Einstein Allee, D 89069 Ulm, Germany
    Curr Genet 34:313-7. 1998
    ..frame (orf) is identified in the Arabidopsis thaliana mitochondrial genome, overlapping the 3'-end region of the cox3 gene...
  82. ncbi Molecular and biochemical analysis of Saccharomyces cerevisiae cox1 mutants
    C Lemaire
    Centre de Genetique Moleculaire, Laboratoire propre du CNRS associé à l Université Pierre et Marie Curie, F 91198 Gif sur Yvette Cedex, France
    Curr Genet 34:138-45. 1998
    ..A comparison of the steady state levels of Cox1p through Cox4p in the COX1, COX2, COX3 and COX4 mutants shows the interdependance of the accumulation of these four subunits in the mitochondrial membranes...
  83. pmc Site-directed mutagenesis of a Saccharomyces cerevisiae mitochondrial translation initiation codon
    L S Folley
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Genetics 129:659-68. 1991
    ..The mutation, cox3-1, substantially reduced, but did not eliminate, translation of cytochrome c oxidase subunit III (coxIII)...
  84. ncbi Molecular phylogeny of Allomyces macrogynus: congruency between nuclear ribosomal RNA- and mitochondrial protein-based trees
    B Paquin
    Departement de Biochimie, Universite de Montreal, Canada
    J Mol Evol 41:657-65. 1995
    ..rRNA genes (rns) and the mitochondrial genes coding for subunits 1 and 3 of the cytochrome oxidase (cox1 and cox3, respectively) of the chytridiomycete Allomyces macrogynus...
  85. ncbi Mitochondrial DNA mutations in Cuban optic and peripheral neuropathy
    D R Johns
    Department of Neurology, Harvard Medical School, Beth Israel Hospital, Boston, MA 02115
    J Neuroophthalmol 14:135-40. 1994
    ..mtDNA mutation at nucleotide position 9438 and a novel mutation at nucleotide position 9738 in the cytochrome c oxidase subunit III gene. None of the Cuban patients harbored any of the 8 other LHON-associated mtDNA mutations...
  86. pmc Reduced dosage of genes encoding ribosomal protein S18 suppresses a mitochondrial initiation codon mutation in Saccharomyces cerevisiae
    L S Folley
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Genetics 137:369-79. 1994
    A yeast mitochondrial translation initiation codon mutation affecting the gene for cytochrome oxidase subunit III (COX3) was partially suppressed by a spontaneous nuclear mutation...
  87. pmc Nucleotide sequence of the cox3 gene from Chondrus crispus: evidence that UGA encodes tryptophan and evolutionary implications
    C Boyen
    Centre d Etudes d Océanologie et de Biologie Marine, CNRS UPR 4601, Universite P and M Curie, Roscoff, France
    Nucleic Acids Res 22:1400-3. 1994
    ..However, phylogenetic analyses of cox3 amino acid and nucleotide sequences indicate that C...
  88. ncbi Cytochrome c oxidase mutations in Leber hereditary optic neuropathy
    D R Johns
    Department of Neurology, Beth Israel Hospital, Harvard Medical School, Boston, MA 02115
    Biochem Biophys Res Commun 196:810-5. 1993
    New mitochondrial DNA mutations were discovered in the cytochrome c oxidase subunit III gene in 8 independent Leber hereditary optic neuropathy probands...
  89. pmc Interactions among three proteins that specifically activate translation of the mitochondrial COX3 mRNA in Saccharomyces cerevisiae
    N G Brown
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Mol Cell Biol 14:1045-53. 1994
    ..with the yeast inner mitochondrial membrane, specifically activate translation of the mitochondrially encoded COX3 mRNA...
  90. pmc Suppression of a defect in the 5' untranslated leader of mitochondrial COX3 mRNA by a mutation affecting an mRNA-specific translational activator protein
    M C Costanzo
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Mol Cell Biol 13:4806-13. 1993
    Translation of the Saccharomyces cerevisiae mitochondrial COX3 mRNA, encoding subunit III of cytochrome c oxidase, specifically requires the action of the nuclear gene products PET54, PET122, and PET494 at a site encoded in the 612-base 5'..
  91. pmc Pet127p, a membrane-associated protein involved in stability and processing of Saccharomyces cerevisiae mitochondrial RNAs
    G Wiesenberger
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703, USA
    Mol Cell Biol 17:2816-24. 1997
    ..mutations that inactivate the Saccharomyces cerevisiae gene PET127 dramatically increased the levels of mutant COX3 and COX2 mitochondrial mRNAs that were destabilized by mutations in their 5' untranslated leaders...
  92. pmc Functional polypeptides can be synthesized from human mitochondrial transcripts lacking termination codons
    Zofia M A Chrzanowska-Lightowlers
    School of Neurology, The Medical School, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, NE2 4HH, U K
    Biochem J 377:725-31. 2004
    ..to carry a microdeletion, resulting in the loss of the termination codon for MTATP6 and in its juxtaposition with MTCO3. Cell lines from this patient exhibited low steady-state levels of RNA14, the bi-cistronic transcript encoding ..
  93. ncbi The complete maternal and paternal mitochondrial genomes of the Mediterranean mussel Mytilus galloprovincialis: implications for the doubly uniparental inheritance mode of mtDNA
    Athanasia Mizi
    Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, Panepistimioupolis, Athens, Greece
    Mol Biol Evol 22:952-67. 2005
    ..Both lack the ATPase8 subunit gene, have two tRNAs for methionine and a longer open-reading frame for cox3 than seen in other mollusks...
  94. ncbi Evolutionary rates, divergence dates, and the performance of mitochondrial genes in Bayesian phylogenetic analysis
    Rachel Lockridge Mueller
    Museum of Vertebrate Zoology, University of California, 3101 Valley Life Sciences Building Berkeley, California 94720 3160, USA
    Syst Biol 55:289-300. 2006
    ..Despite having conserved amino acid sequences, cox1, cox2, cox3, and cob have the fastest mean rates of nucleotide substitution, and the greatest variation in rates, whereas rrnS ..
  95. ncbi Melatonin as antioxidant, geroprotector and anticarcinogen
    Vladimir N Anisimov
    Department of Carcinogenesis and Oncogerontology, N N Petrov Research Institute of Oncology, Pesochny 2, St Petersburg 197758, Russia
    Biochim Biophys Acta 1757:573-89. 2006
    ..Melatonin also increased the expression of some mitochondrial genes (16S, cytochrome c oxidases 1 and 3 (COX1 and COX3), and NADH dehydrogenases 1 and 4 (ND1 and ND4)), which agrees with its ability to inhibit free radical processes...
  96. ncbi The complete mitochondrial genome of the vascular wilt fungus Verticillium dahliae: a novel gene order for Verticillium and a diagnostic tool for species identification
    Malena P Pantou
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistemiopolis, Greece
    Curr Genet 50:125-36. 2006
    ..Sordariomycetes, namely rnl-trn ((11-12))-nad2-nad3, nad4L-nad5-cob-cox1, nad1-nad4-atp8-atp6 and rns-trn ((1-5))-cox3-trn ((1-5))-nad6-trn ((2-5))...
  97. ncbi The mitochondrial DNA of Allomyces macrogynus: the complete genomic sequence from an ancestral fungus
    B Paquin
    Departement de Biochimie, Universite de Montreal, Centre Ville, Canada
    J Mol Biol 255:688-701. 1996
    ..atp6, atp8 and atp9), apocytochrome b(cob), three subunits of the cytochrome oxidase complex (cox1, cox2 and cox3), and seven subunits of the NADH dehydrogenase complex (nad1, nad2, nad3, nad4, nad4L, nad5 and nad6)...
  98. ncbi The mitochondrial genome of Priapulus caudatus Lamarck (Priapulida: Priapulidae)
    Bonnie L Webster
    Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
    Gene 389:96-105. 2007
    ..The gene order was: cox1, cox2, trnK, trnD, atp8, atp6, cox3, trnG, nad3, trnA, trnR, trnN, rrnS, trnV, rrnL, trnL(yaa), trnL(nag), nad1, -trnS(nga), -cob, -nad6, trnP, -trnT, ..
  99. ncbi Molecular phylogeography of two sibling species of Eurema butterflies
    Satoko Narita
    Laboratory of Applied Entomology and Zoology, Faculty of Horticulture, Chiba University, Matsudo, Chiba 271 8510, Japan
    Genetica 131:241-53. 2007
    ..nucleotide sequence variation of three mitochondrial regions: cytochrome c oxidase subunit I (COI), cytochrome c oxidase subunit III (COIII) and NADH dehydrogenase subunit 5 (ND5)...
  100. pmc Heterocyst development and diazotrophic metabolism in terminal respiratory oxidase mutants of the cyanobacterium Anabaena sp. strain PCC 7120
    Ana Valladares
    Instituto de Bioquimica Vegetal y Fotosintesis, Centro de Investigaciones Cientificas Isla de la Cartuja, Americo Vespucio 49, E 41092 Seville, Spain
    J Bacteriol 189:4425-30. 2007
    ..strain PCC 7120 bearing inactivated cox2 and/or cox3 genes, encoding heterocyst-specific terminal respiratory oxidases...

Research Grants14

  1. HYDROPHOBIC ASSOCIATIONS OF MEMBRANE COMPLEXES
    NEAL ROBINSON; Fiscal Year: 1990
    ..Together, these four approaches will probe the importance of specific lipids and subunits in the structure and function of this inner mitochondiral membrane protein...
  2. TRANSLATIONAL CONTROL OF YEAST MITOCHONDRIAL GENES
    Thomas Fox; Fiscal Year: 2001
    ..specific translational activators play key roles in localizing translation of the yeast mitochondrial COX2 and COX3 mRNAs to the inner membrane, and in their regulation...
  3. The Impact of HLA in Children Receiving HAART
    Akihiko Saitoh; Fiscal Year: 2007
    ..This research will also suggest modes of pathogenesis that can lead to the development of vaccine strategies. ..
  4. mt-Nd2 and Resistance to Autoimmune Diabetes
    Clayton Mathews; Fiscal Year: 2007
    ..As the SNP and its accompanying amino acid change in the T1D resistant human population and ALR mouse are similar, it is likely that the information gleened from this application can directly impact future work to prevent or cure T1D. ..