CISD3

Summary

Gene Symbol: CISD3
Description: CDGSH iron sulfur domain 3
Summary: CISD3 is a member of the CDGSH domain-containing family, which may play a role in regulating electron transport and oxidative phosphorylation (Wiley et al., 2007 [PubMed 17376863]).[supplied by OMIM]
Alias: Miner2, mitoNEET related 2
Species: human

Publications

  1. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity
    Sandra E Wiley
    Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 104:5318-23
  2. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster
    Sandra E Wiley
    Department of Pharmacology, University of California, San Diego, La Jolla, California 92093, USA
    J Biol Chem 282:23745-9

Detail Information

Publications2

  1. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity
    Sandra E Wiley
    Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 104:5318-23
    ..Cardiac mitochondria isolated from mitoNEET-null mice demonstrate a reduced oxidative capacity, suggesting that mito- NEET is an important iron-containing protein involved in the control of maximal mitochondrial respiratory rates...
  2. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster
    Sandra E Wiley
    Department of Pharmacology, University of California, San Diego, La Jolla, California 92093, USA
    J Biol Chem 282:23745-9
    ..mitoNEET is the first identified 2Fe-2S-containing protein located in the outer mitochondrial membrane. Based on the biophysical data and domain fusion analysis, mitoNEET may function in Fe-S cluster shuttling and/or in redox reactions...