CHST7

Summary

Gene Symbol: CHST7
Description: carbohydrate sulfotransferase 7
Alias: C6ST-2, GST-5, carbohydrate sulfotransferase 7, N-acetylglucosamine 6-O-sulfotransferase 4, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7, chondroitin 6-sulfotransferase-2, galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5, glcNAc6ST-4, gn6st-4
Species: human
Products:     CHST7

Top Publications

  1. Lin R, Rosahl T, Whiting P, Fawcett J, Kwok J. 6-Sulphated chondroitins have a positive influence on axonal regeneration. PLoS ONE. 2011;6:e21499 pubmed publisher
  2. Oliveira Ferrer L, Heßling A, Trillsch F, Mahner S, Milde Langosch K. Prognostic impact of chondroitin-4-sulfotransferase CHST11 in ovarian cancer. Tumour Biol. 2015;36:9023-30 pubmed publisher
    ..For CHST3 and CHST7, no significant differences were found between the two groups...
  3. Bernstein H, Compans R. Sulfation of the human immunodeficiency virus envelope glycoprotein. J Virol. 1992;66:6953-9 pubmed
    ..Sulfation is a major determinant of negative charge and could play a role in biological functions and antigenic properties of HIV glycoproteins. ..
  4. Shilatifard A, Merkle R, Helland D, Welles J, Haseltine W, Cummings R. Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine. J Virol. 1993;67:943-52 pubmed
    ..Charge analysis of the [3H]galactose- and [3H]glucosamine-labeled glycopeptides from gp120 and gp160 indicates that approximately 14% of the complex-type N-linked oligosaccharides are sulfated. ..
  5. Kitagawa H, Fujita M, Ito N, Sugahara K. Molecular cloning and expression of a novel chondroitin 6-O-sulfotransferase. J Biol Chem. 2000;275:21075-80 pubmed
  6. Uchimura K, Fasakhany F, Kadomatsu K, Matsukawa T, Yamakawa T, Kurosawa N, et al. Diversity of N-acetylglucosamine-6-O-sulfotransferases: molecular cloning of a novel enzyme with different distribution and specificities. Biochem Biophys Res Commun. 2000;274:291-6 pubmed
    ..The distribution and the specificity of GlcNAc6ST are different from those of GlcNAc6STs identified previously. ..
  7. Thiselton D, McDowall J, Brandau O, Ramser J, d Esposito F, Bhattacharya S, et al. An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders. Genomics. 2002;79:560-72 pubmed
    ..68318), carbohydrate sulfotransferase-7 (CHST7), regucalcin (RGN), inactivation-escape-1 (INE1), the human ortholog of mouse neuronal protein 15...
  8. Bhakta S, Bartes A, Bowman K, Kao W, Polsky I, Lee J, et al. Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5). J Biol Chem. 2000;275:40226-34 pubmed

Detail Information

Publications8

  1. Lin R, Rosahl T, Whiting P, Fawcett J, Kwok J. 6-Sulphated chondroitins have a positive influence on axonal regeneration. PLoS ONE. 2011;6:e21499 pubmed publisher
  2. Oliveira Ferrer L, Heßling A, Trillsch F, Mahner S, Milde Langosch K. Prognostic impact of chondroitin-4-sulfotransferase CHST11 in ovarian cancer. Tumour Biol. 2015;36:9023-30 pubmed publisher
    ..For CHST3 and CHST7, no significant differences were found between the two groups...
  3. Bernstein H, Compans R. Sulfation of the human immunodeficiency virus envelope glycoprotein. J Virol. 1992;66:6953-9 pubmed
    ..Sulfation is a major determinant of negative charge and could play a role in biological functions and antigenic properties of HIV glycoproteins. ..
  4. Shilatifard A, Merkle R, Helland D, Welles J, Haseltine W, Cummings R. Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine. J Virol. 1993;67:943-52 pubmed
    ..Charge analysis of the [3H]galactose- and [3H]glucosamine-labeled glycopeptides from gp120 and gp160 indicates that approximately 14% of the complex-type N-linked oligosaccharides are sulfated. ..
  5. Kitagawa H, Fujita M, Ito N, Sugahara K. Molecular cloning and expression of a novel chondroitin 6-O-sulfotransferase. J Biol Chem. 2000;275:21075-80 pubmed
  6. Uchimura K, Fasakhany F, Kadomatsu K, Matsukawa T, Yamakawa T, Kurosawa N, et al. Diversity of N-acetylglucosamine-6-O-sulfotransferases: molecular cloning of a novel enzyme with different distribution and specificities. Biochem Biophys Res Commun. 2000;274:291-6 pubmed
    ..The distribution and the specificity of GlcNAc6ST are different from those of GlcNAc6STs identified previously. ..
  7. Thiselton D, McDowall J, Brandau O, Ramser J, d Esposito F, Bhattacharya S, et al. An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders. Genomics. 2002;79:560-72 pubmed
    ..68318), carbohydrate sulfotransferase-7 (CHST7), regucalcin (RGN), inactivation-escape-1 (INE1), the human ortholog of mouse neuronal protein 15...
  8. Bhakta S, Bartes A, Bowman K, Kao W, Polsky I, Lee J, et al. Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5). J Biol Chem. 2000;275:40226-34 pubmed