CAVIN2

Summary

Gene Symbol: CAVIN2
Description: caveolae associated protein 2
Alias: PS-p68, SDPR, SDR, cavin-2, caveolae-associated protein 2, phosphatidylserine-binding protein, serum deprivation response, serum deprivation-response protein
Species: human
Products:     CAVIN2

Top Publications

  1. Mineo C, Ying Y, Chapline C, Jaken S, Anderson R. Targeting of protein kinase Calpha to caveolae. J Cell Biol. 1998;141:601-10 pubmed
    ..A 68-kD PKCalpha-binding protein identified as sdr (serum deprivation response) was isolated by interaction cloning and localized to caveolae...
  2. Burgener R, Wolf M, Ganz T, Baggiolini M. Purification and characterization of a major phosphatidylserine-binding phosphoprotein from human platelets. Biochem J. 1990;269:729-34 pubmed
    ..Platelets appear to be the only blood cells containing PS-p68, which was not detected in neutrophils, monocytes and lymphocytes. ..
  3. Gustincich S, Vatta P, Goruppi S, Wolf M, Saccone S, Della Valle G, et al. The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein. Genomics. 1999;57:120-9 pubmed
    The serum deprivation response gene (SDPR, alias sdr) has been previously isolated for its high mRNA expression in serum-starved cells compared to contact-inhibited NIH3T3 cells; such regulation is not observed in single-oncogene ..
  4. Ogata T, Ueyama T, Isodono K, Tagawa M, Takehara N, Kawashima T, et al. MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol. 2008;28:3424-36 pubmed publisher
    ..Using the yeast two-hybrid system, we identified the serum deprivation response (SDPR) protein, a phosphatidylserine-binding protein, as a MURC-binding protein...
  5. Hansen C, Bright N, Howard G, Nichols B. SDPR induces membrane curvature and functions in the formation of caveolae. Nat Cell Biol. 2009;11:807-14 pubmed publisher
    ..Here we show that loss of SDPR (serum deprivation protein response) causes loss of caveolae...
  6. Ludwig A, Howard G, Mendoza Topaz C, Deerinck T, Mackey M, Sandin S, et al. Molecular composition and ultrastructure of the caveolar coat complex. PLoS Biol. 2013;11:e1001640 pubmed publisher
    ..The core interactions between caveolin 1 and cavin 1 are independent of cavin 2, cavin 3, and EHD2 expression, and the cavins themselves can still interact in the absence of caveolin 1...
  7. Gustincich S, Schneider C. Serum deprivation response gene is induced by serum starvation but not by contact inhibition. Cell Growth Differ. 1993;4:753-60 pubmed
    ..Here, we describe a gene, named sdr (serum deprivation response), whose mRNA level is highly induced in serum starved but not in density dependent growth arrested ..
  8. McMahon K, Zajicek H, Li W, Peyton M, Minna J, Hernandez V, et al. SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function. EMBO J. 2009;28:1001-15 pubmed publisher
    ..We conclude that SRBC (sdr-related gene product that binds to c-kinase) and two other family members [PTRF (Pol I and transcription release factor) and SDPR] function as caveolin adapter molecules that regulate caveolae function.
  9. Strehse J, Protopapas N, Maser E. Carbonyl reductase sniffer from the model organism daphnia: Cloning, substrate determination and inhibitory sensitivity. Chem Biol Interact. 2019;: pubmed publisher
    ..conclusion, the present results on sniffer from the protein superfamily of the short-chain dehydrogenase/reductase (SDR) in Daphnia ssp...

More Information

Publications123 found, 100 shown here

  1. Krawczyk K, Hansson J, Nilsson H, Krawczyk K, Swärd K, Johansson M. Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1. BMC Nephrol. 2017;18:320 pubmed publisher
    ..Viral overexpression of MKL1 induced caveolin-1/CAV1, caveolin-2/CAV2 and SDPR/CAVIN2. In kidney tissue, the mRNA level of MKL1 correlated with the mRNA levels for caveolin-1/CAV1, caveolin-2/CAV2 and ..
  2. Wang P, Zheng D, Wang Y, Liang R. One 3-oxoacyl-(acyl-Carrier-protein) reductase functions as 17β-hydroxysteroid dehydrogenase in the estrogen-degrading Pseudomonas putida SJTE-1. Biochem Biophys Res Commun. 2018;505:910-916 pubmed publisher
    ..showed it contained the two consensus regions and the conserved residues of short-chain dehydrogenase/reductase (SDR)...
  3. Wu C, Chiu T, Lin Y, Huang Y, Li L, Yang T. Role of smeU1VWU2X Operon in Alleviation of Oxidative Stresses and Occurrence of Sulfamethoxazole-Trimethoprim-Resistant Mutants in Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 2018;62: pubmed publisher
    ..additional genes, smeU1 and smeU2, which encode proteins of the short-chain dehydrogenase/reductase (SDR) family...
  4. Yang S, Jan Y, Mishin V, Heck D, Laskin D, Laskin J. Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells. Chem Res Toxicol. 2017;30:1406-1418 pubmed publisher
    ..DCXR is a member of the short-chain dehydrogenase/reductase (SDR) superfamily...
  5. Zhang D, Liu Z, Lu Z, Sun W, Ma X, Zhang P, et al. Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma. Onco Targets Ther. 2018;11:7133-7142 pubmed publisher
    ..Hydroxysteroid dehydrogenase-like 2 (HSDL2) belongs to the SDR subfamily of oxidoreductases, and it is involved in glioma oncogenesis, as it can promote cell proliferation and ..
  6. Endo S, Miyagi N, Matsunaga T, Hara A, Ikari A. Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenase. Biochem Biophys Res Commun. 2016;472:231-6 pubmed publisher
    ..Thus, DHRS11 represents a novel type of 17β-hydroxysteroid dehydrogenase with unique catalytic properties and tissue distribution. ..
  7. Feng S, Ma J, Yang J, Hu Z, Zhu L, Bi H, et al. Ralstonia solanacearum fatty acid composition is determined by interaction of two 3-ketoacyl-acyl carrier protein reductases encoded on separate replicons. BMC Microbiol. 2015;15:223 pubmed publisher
    ..conserved catalytic triad and the N-terminal cofactor binding sequence of the short chain dehydrogenase/reductase (SDR) family...
  8. Stapelfeld C, Maser E. Sex hormones reduce NNK detoxification through inhibition of short-chain dehydrogenases/reductases and aldo-keto reductases in vitro. Chem Biol Interact. 2017;276:167-173 pubmed publisher
    ..Detoxification of NNK through carbonyl reduction is catalyzed by members of the AKR- and the SDR-superfamilies which include AKR1B10, AKR1C1, AKR1C2, AKR1C4, 11?-HSD1 and CBR1...
  9. Tome M, Herndon J, Schaefer C, Jacobs L, Zhang Y, Jarvis C, et al. P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain. J Cereb Blood Flow Metab. 2016;36:1913-1928 pubmed
    ..increased endothelial cell luminal staining of polymerase 1 and transcript release factor/cavin1 and serum deprivation response protein/cavin2, two caveolar scaffold proteins, without changing caveolin1 or protein kinase C delta binding ..
  10. Sone Y, Nakamura S, Sasaki M, Hasebe F, Kim S, Funa N. Bacterial Enzymes Catalyzing the Synthesis of 1,8-Dihydroxynaphthalene, a Key Precursor of Dihydroxynaphthalene Melanin, from Sorangium cellulosum. Appl Environ Microbiol. 2018;84: pubmed publisher
    ..synthesis of 1,8-DHN is composed of a type I PKS, naphthol reductases of the short-chain dehydrogenase/reductase (SDR) superfamily, and scytalone dehydratase (SD)...
  11. Zhang H, Ji Y, Wang Y, Zhang X, Yu Y. Cloning and characterization of a novel β-ketoacyl-ACP reductase from Comamonas testosteroni. Chem Biol Interact. 2015;234:213-20 pubmed publisher
    ..DNA sequence comparison showed that BKR belongs to the short-chain alcohol dehydrogenase (SDR) family. Our results showed that BKR is necessary for the degradation of steroid hormones in C. testosteroni...
  12. Lago D, Humann F, Barchuk A, Abraham K, Hartfelder K. Differential gene expression underlying ovarian phenotype determination in honey bee, Apis mellifera L., caste development. Insect Biochem Mol Biol. 2016;79:1-12 pubmed publisher
    ..This revealed a significant up-regulation for two genes, a short chain dehydrogenase reductase (sdr) and a heat shock protein 90 (hsp90)...
  13. Wu Y, Huang P, Xiong G, Maser E. Identification and isolation of a regulator protein for 3,17β-HSD expressional regulation in Comamonas testosteroni. Chem Biol Interact. 2015;234:197-204 pubmed publisher
    ..testosteroni is a member of the short-chain dehydrogenase/reductase (SDR) superfamily. It is an inducible and key enzyme in steroid degradation...
  14. Hara A, Endo S, Matsunaga T, El Kabbani O, Miura T, Nishinaka T, et al. Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. Biochem Pharmacol. 2017;138:185-192 pubmed publisher
    Human carbonyl reductase 1 (CBR1), a member of the short-chain dehydrogenase/reductase (SDR) superfamily, reduces a variety of carbonyl compounds including endogenous isatin, prostaglandin E2 and 4-oxo-2-nonenal...
  15. Hua T, Wu D, Ding W, Wang J, Shaw N, Liu Z. Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids. J Biol Chem. 2012;287:28956-65 pubmed publisher
    ..seen in the active site of mDCR, which together with a lysine and an asparagine have been deemed a hallmark of the SDR family of enzymes...
  16. Agnihotri A, Gupta P, Dwivedi A, Seth C. Counteractive mechanism (s) of salicylic acid in response to lead toxicity in Brassica juncea (L.) Czern. cv. Varuna. Planta. 2018;248:49-68 pubmed publisher
    ..Lead accumulation in root, shoot and its sub-cellular distribution ratio (SDR) and localization was also determined using atomic absorption spectroscopy (AAS) and rhodizonate-dye staining ..
  17. Moon J, Liu Z. Direct enzyme assay evidence confirms aldehyde reductase function of Ydr541cp and Ygl039wp from Saccharomyces cerevisiae. Yeast. 2015;32:399-407 pubmed publisher
    ..is a recently characterized member of an intermediate subfamily within the short-chain dehydrogenase/reductase (SDR) superfamily that clarified mechanisms of in situ detoxification of 2-furaldehyde and 5-hydroxymethyl-2-furaldehyde ..
  18. Le Cras T, Kim D, Markham N, Abman A. Early abnormalities of pulmonary vascular development in the Fawn-Hooded rat raised at Denver's altitude. Am J Physiol Lung Cell Mol Physiol. 2000;279:L283-91 pubmed
    ..the lungs of fetal, 1- and 7-day-old, 3-week-old, and adult FHRs compared with that in the normal Sprague-Dawley (SDR) and Fischer rat strains, all raised at Denver's altitude...
  19. Stapelfeld C, Neumann K, Maser E. Different inhibitory potential of sex hormones on NNK detoxification in vitro: A possible explanation for gender-specific lung cancer risk. Cancer Lett. 2017;405:120-126 pubmed publisher
    ..It is mediated by different carbonyl reductases of the SDR (CBR1 and 11βHSD1) and AKR (AKR1B10, AKR1C1, AKR1C2 and AKR1C4) superfamilies...
  20. Yamada T, Nanashima N, Shimizu T, Nakazawa Y, Nakazawa M, Tsuchida S. Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene. Biochem J. 2015;471:293-305 pubmed publisher
    ..analysis revealed that expression level of the Nufip2 gene in the HiSER eye was 40% of that in the SDR eye...
  21. Richardson B, Rossi D. Recreational concentrations of alcohol enhance synaptic inhibition of cerebellar unipolar brush cells via pre- and postsynaptic mechanisms. J Neurophysiol. 2017;118:267-279 pubmed publisher
    ..Sprague-Dawley rat (SDR) UBCs exhibited sIPSCs mediated by GABAARs, GlyRs, or both, and EtOH dose-dependently (10, 26, 52 mM) ..
  22. Bi S, Xiu B, Ye J, Dong Y. Target-Catalyzed DNA Four-Way Junctions for CRET Imaging of MicroRNA, Concatenated Logic Operations, and Self-Assembly of DNA Nanohydrogels for Targeted Drug Delivery. ACS Appl Mater Interfaces. 2015;7:23310-9 pubmed publisher
    ..DNA four-way junction (DNA-4WJ) on the basis of toehold-mediated DNA strand displacement reaction (TM-SDR), which is readily applied in enzyme-free amplified chemiluminescence resonance energy transfer (CRET) imaging of ..
  23. Haq I, Dini Andreote F, van Elsas J. Transcriptional Responses of the Bacterium Burkholderia terrae BS001 to the Fungal Host Lyophyllum sp. Strain Karsten under Soil-Mimicking Conditions. Microb Ecol. 2017;73:236-252 pubmed publisher
    ..coupled to an oxidative stress response, and two genes encoding short-chain dehydrogenases/oxidoreductases (SDR), were highly upregulated...
  24. Li W, Jiang W, Ding Y, Wang L. Highly selective and sensitive detection of miRNA based on toehold-mediated strand displacement reaction and DNA tetrahedron substrate. Biosens Bioelectron. 2015;71:401-406 pubmed publisher
    ..counting method for miRNA analysis was proposed based on toehold-mediated strand displacement reaction (SDR) and DNA tetrahedron substrate...
  25. Beck K, Kaserer T, Schuster D, Odermatt A. Virtual screening applications in short-chain dehydrogenase/reductase research. J Steroid Biochem Mol Biol. 2017;171:157-177 pubmed publisher
    Several members of the short-chain dehydrogenase/reductase (SDR) enzyme family play fundamental roles in adrenal and gonadal steroidogenesis as well as in the metabolism of steroids, oxysterols, bile acids, and retinoids in peripheral ..
  26. Moreno L, Ahmed A, Brankovics B, Cuomo C, Menken S, Taj Aldeen S, et al. Genomic Understanding of an Infectious Brain Disease from the Desert. G3 (Bethesda). 2018;8:909-922 pubmed publisher
    ..Specifically, protein family contractions were found, including short-chain dehydrogenase/reductase SDR, the cytochrome P450 (CYP) (E-class), and the G-protein β WD-40 repeat...
  27. Wang X, Ma M, Liu Z, Xiang Q, Li X, Liu N, et al. GRE2 from Scheffersomyces stipitis as an aldehyde reductase contributes tolerance to aldehyde inhibitors derived from lignocellulosic biomass. Appl Microbiol Biotechnol. 2016;100:6671-6682 pubmed publisher
    ..analysis indicated that it is a member of the subclass "intermediate" of the short-chain dehydrogenase/reductase (SDR) superfamily. Although GRE2 from S. stipitis is similar to GRE2 from S...
  28. Adams M, Lee S, Belyaeva O, Wu L, Kedishvili N. Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10. Chem Biol Interact. 2017;276:88-94 pubmed publisher
    ..dehydrogenase 10 (RDH10, SDR16C4), which belongs to the 16C family of the short chain dehydrogenase/reductase (SDR) superfamily of proteins, is the major enzyme responsible for the oxidation of retinol to retinaldehyde for RA ..
  29. Pikkemaat M, Melander O, Bengtsson Boström K. Association between copeptin and declining glomerular filtration rate in people with newly diagnosed diabetes. The Skaraborg Diabetes Register. J Diabetes Complications. 2015;29:1062-5 pubmed publisher
    ..People with newly diagnosed type 2 diabetes in 1996-1998 from Skaraborg Diabetes Register (SDR) were reinvestigated in 2008-2010. Copeptin concentration at the time of diagnosis was determined...
  30. Lukaszewska Kuska M, Wirstlein P, Majchrowski R, Dorocka Bobkowska B. Osteoblastic cell behaviour on modified titanium surfaces. Micron. 2018;105:55-63 pubmed publisher
    ..In the case of the blasted and etched samples, etching decreased the surface development as indicated by the Sdr and also reduced the amount of chemical compounds incorporated into the surfaces during the blasting procedure...
  31. Liu H, Lv J, Qi X, Ding Y, Li D, Hu L, et al. The carriage of the serine-aspartate repeat protein-encoding sdr genes among Staphylococcus aureus lineages. Braz J Infect Dis. 2015;19:498-502 pubmed publisher
    The serine-aspartate repeat proteins (Sdr) are members of a family of surface proteins and contribute to the pathogenicity of Staphylococcus aureus. Among 288 S...
  32. Fronza B, Rueggeberg F, Braga R, Mogilevych B, Soares L, Martin A, et al. Monomer conversion, microhardness, internal marginal adaptation, and shrinkage stress of bulk-fill resin composites. Dent Mater. 2015;31:1542-51 pubmed publisher
    ..Bulk-fill composites tested were Surefil SDR (SDR), Filtek Bulk-Fill (FBF), Tetric EvoCeram Bulk-Fill (TEC), and EverX Posterior (EXP)...
  33. Samadder N, Smith K, Wong J, Hanson H, Boucher K, Burt R, et al. Familial Risk of Biliary Tract Cancers: A Population-Based Study in Utah. Dig Dis Sci. 2016;61:3627-3632 pubmed
    ..We quantified the risk of BTC in first-degree (FDR), second-degree (SDR), and first cousin (FC) relatives of individuals with BTC, stratified by tumor subsite...
  34. Baijnath S, Murugesan S, Mackraj I, Gathiram P, Moodley J. The effects of sildenafil citrate on urinary podocin and nephrin mRNA expression in an L-NAME model of pre-eclampsia. Mol Cell Biochem. 2017;427:59-67 pubmed publisher
    ..One hundred and twenty Sprague-Dawley rats (SDR) were divided into five groups like pregnant control (PC), early-onset PE (EOPE), late-onset PE(LOPE), early and ..
  35. Zhao K, Zeng J, Zhao T, Zhang H, Qiu F, Yang C, et al. Enhancing Tropane Alkaloid Production Based on the Functional Identification of Tropine-Forming Reductase in Scopolia lurida, a Tibetan Medicinal Plant. Front Plant Sci. 2017;8:1745 pubmed publisher
    ..Here, we report on the isolation and characterization of a putative short chain dehydrogenase (SDR) gene. Sequence analysis showed that SlTRI belonged to the SDR family...
  36. Cheng S, Yang J, Liao T, Zhu X, Suo Y, Zhang P, et al. Transcriptomic changes following synthesis of a Populus full-sib diploid and allotriploid population with different heterozygosities driven by three types of 2n female gamete. Plant Mol Biol. 2015;89:493-510 pubmed publisher
    ..to produce triploids of Populus [originating from first-division restitution (FDR), second-division restitution (SDR), and postmeiotic restitution (PMR) 2n eggs]...
  37. He C, Huang X, Liu Y, Li F, Yang Y, Tao H, et al. Structural insights on mouse L-threonine dehydrogenase: A regulatory role of Arg180 in catalysis. J Struct Biol. 2015;192:510-518 pubmed publisher
    Mouse L-threonine dehydrogenase (mTDH), which belongs to the short-chain dehydrogenase/reductase (SDR) superfamily and mediates threonine catabolism, plays pivotal roles in both powerful biosynthesis and signaling in mouse stem cells and ..
  38. Alshali R, Salim N, Sung R, Satterthwaite J, Silikas N. Analysis of long-term monomer elution from bulk-fill and conventional resin-composites using high performance liquid chromatography. Dent Mater. 2015;31:1587-98 pubmed publisher
    ..Six bulk-fill (SureFil SDR, Venus Bulk Fill, X-tra base, Filtek Bulk Fill flowable, Sonic Fill, and Tetric EvoCeram Bulk Fill) and eight ..
  39. Arnaud M, Salvo F, Ahmed I, Robinson P, Moore N, Bégaud B, et al. A Method for the Minimization of Competition Bias in Signal Detection from Spontaneous Reporting Databases. Drug Saf. 2016;39:251-60 pubmed publisher
    The two methods for minimizing competition bias in signal of disproportionate reporting (SDR) detection--masking factor (MF) and masking ratio (MR)--have focused on the strength of disproportionality for identifying competitors and have ..
  40. Sommershof A, Scheuermann L, Koerner J, Groettrup M. Chronic stress suppresses anti-tumor TCD8+ responses and tumor regression following cancer immunotherapy in a mouse model of melanoma. Brain Behav Immun. 2017;65:140-149 pubmed publisher
    ..Exposure of mice to social disruption stress (SDR), a well-established model mimicking psychological chronic stress in humans, significantly impaired tumor ..
  41. Hauben M, Hung E, Hanretta K, Bangalore S, Snow V. Safety of Perflutren Ultrasound Contrast Agents: A Disproportionality Analysis of the US FAERS Database. Drug Saf. 2015;38:1127-39 pubmed publisher
    ..A signal of disproportionate reporting (SDR) was defined as EB05 >2. Overall, 18/380 Preferred Terms and 1/83 Standardized Medical Queries had SDRs...
  42. Engeli R, Rhouma B, Sager C, Tsachaki M, Birk J, Fakhfakh F, et al. Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development. J Steroid Biochem Mol Biol. 2016;155:147-54 pubmed publisher
    ..on 17β-HSD3 is located in a motif highly conserved in 17β-HSDs and other short-chain dehydrogenase/reductase (SDR) enzymes...
  43. Ma T, Chen Q, Gui M, Li C, Ni J. Simultaneous denitrification and phosphorus removal by Agrobacterium sp. LAD9 under varying oxygen concentration. Appl Microbiol Biotechnol. 2016;100:3337-46 pubmed publisher
    ..received increasing attention, few studies have been made on simultaneous denitrification and phosphorus removal (SDPR) under aerobic condition. In this study, SDPR by an efficient aerobic denitrifier, Agrobacterium sp...
  44. Kinatukara P, Patel K, Haque A, Singh R, Gokhale R, Sankaranarayananan R. Structural insights into the regulation of NADPH binding to reductase domains of nonribosomal peptide synthetases: A concerted loop movement model. J Struct Biol. 2016;194:368-74 pubmed publisher
    ..Reductase domains (R-domains) of short-chain dehydrogenase/reductase (SDR) family offer an alternative offloading mechanism by reducing 4'-phosphopantetheine (4'-PPant) arm-tethered ..
  45. Xiu F, Weng H, Qi Y, Yu G, Zhang Z, Zhang F. A novel reutilization method for waste printed circuit boards as flame retardant and smoke suppressant for poly (vinyl chloride). J Hazard Mater. 2016;315:102-9 pubmed publisher
    ..LOI) and char yield (CY) increased with increasing SCWO-treated PCBs content in PVC, while smoke density rating (SDR) and maximum smoke density (MSD) decreased markedly...
  46. Kovanen L, Donner K, Kaunisto M, Partonen T. PRKCDBP (CAVIN3) and CRY2 associate with major depressive disorder. J Affect Disord. 2017;207:136-140 pubmed publisher
    ..The protein kinase C delta binding protein (PRKCDBP, or CAVIN3), similar to the serum deprivation response protein (SDPR, or CAVIN2), reduces metabolic stability of the PER2-CRY2 transcription factor complex that ..
  47. Yadav A, Mehrotra A, Agnihotri S, Swami S. Study of factors influencing response and outcome of Cat-IV regimen in MDRTB patients. Indian J Tuberc. 2016;63:255-261 pubmed publisher
    CAT IV regimen or the standardized drug regimen (SDR) under the Revised National Control Program (RNTCP) uses six second-line anti-tubercular drugs in the initial intensive phase (IP)...
  48. Cheng R, Tao M, Shi Z, Zhang X, Jin Y, Li B. Label-free and sensitive detection of T4 polynucleotide kinase activity via coupling DNA strand displacement reaction with enzymatic-aided amplification. Biosens Bioelectron. 2015;73:138-145 pubmed publisher
    ..exo) from 5' to 3' direction to release a single-stranded DNA as a trigger of DNA strand displacement reaction (SDR)...
  49. Frisbee J, Butcher J, Frisbee S, Olfert I, Chantler P, Tabone L, et al. Increased peripheral vascular disease risk progressively constrains perfusion adaptability in the skeletal muscle microcirculation. Am J Physiol Heart Circ Physiol. 2016;310:H488-504 pubmed publisher
    ..and used a multiscale approach to interrogate microvascular function and outcomes: healthy: Sprague-Dawley rats (SDR) and lean Zucker rats (LZR); mild risk: SDR on high-salt diet (HSD) and SDR on high-fructose diet (HFD); moderate ..
  50. Lempel E, Czibulya Z, Kovacs B, Szalma J, Toth A, Kunsági Máté S, et al. Degree of Conversion and BisGMA, TEGDMA, UDMA Elution from Flowable Bulk Fill Composites. Int J Mol Sci. 2016;17: pubmed publisher
    ..Four millimeter-thick samples were prepared from SureFil SDR Flow (SDR), X-tra Base (XB), Filtek Bulk Fill (FBF) and two and four millimeter samples from Filtek Ultimate Flow (..
  51. Sharma J, Bonfield C, Steinbok P. Selective dorsal rhizotomy for hereditary spastic paraparesis in children. Childs Nerv Syst. 2016;32:1489-94 pubmed publisher
    The aim of this study was to determine the outcomes for children who underwent selective dorsal rhizotomy (SDR) for the treatment of spasticity related to spinal pathology...
  52. Metzler M, Sandell L. Enzymatic Metabolism of Vitamin A in Developing Vertebrate Embryos. Nutrients. 2016;8: pubmed
    ..vitamin A to the active retinoid RA is mediated by retinol dehydrogenase 10 (RDH10) and dehydrogenase/reductase (SDR family) member 3 (DHRS3), two related membrane-bound proteins that functionally activate each other to mediate the ..
  53. Pikkemaat M, Melander O, Hjerpe P, Bengtsson Boström K. Prediction of treatment response in patients with newly diagnosed type 2 diabetes: the Skaraborg diabetes register. J Diabetes Complications. 2017;31:854-858 pubmed publisher
    ..data and blood samples from 460 newly diagnosed type 2 diabetes patients from the Skaraborg diabetes register (SDR) at diagnosis and after 5years and were analyzed with linear and logistic regressions...
  54. Oerum S, Roovers M, Leichsenring M, Acquaviva Bourdain C, Beermann F, Gemperle Britschgi C, et al. Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein. Biochim Biophys Acta Mol Basis Dis. 2017;1863:3294-3302 pubmed publisher
    ..The protein belongs to the short-chain dehydrogenase/reductases (SDR) family and is involved in the catabolism of isoleucine in vivo and steroid metabolism in vitro...
  55. Baig A, Bao X, Haslam R. Proteomic identification of pleckstrin-associated proteins in platelets: possible interactions with actin. Proteomics. 2009;9:4254-8 pubmed publisher
    ..including cytoskeletal reorganization (moesin, radixin and alpha-actinin) and signal transduction (serum deprivation response protein, 17 beta-hydroxysteroid dehydrogenase 4 and factor XIIIA)...
  56. Touyama M, Touyama J, Aguni A. [Postoperative course of a patient undergoing selective dorsal rhizotomy for cerebral palsy]. No To Hattatsu. 2011;43:277-81 pubmed
    Selective dorsal rhizotomy (SDR) is a surgical technique for reducing spasticity associated with cerebral palsy (CP)...
  57. Jiang X, Lai J. Sparse and Dense Hybrid Representation via Dictionary Decomposition for Face Recognition. IEEE Trans Pattern Anal Mach Intell. 2015;37:1067-79 pubmed publisher
    ..A sparse- and dense-hybrid representation (SDR) framework is proposed in this paper to alleviate the problems of SRC...
  58. Saeki K, Chin A, Nonomura G, Hilton J, Chien Y, Marshall S, et al. In vitro evaluation of adhesive characteristics of 4-META/MMA-TBB resin with organic filler. Dent Mater. 2015;31:1567-78 pubmed publisher
    ..EB was used with Z (EBZ) or with a resin marketed for bulk-fill base (SureFil-SDR-flow (EBSF)). Shear bond strengths (Mean ± Standard Deviation (S.D.)) of BF (37.4 ± 2...
  59. Rothmund L, Reichl F, Hickel R, Styllou P, Styllou M, Kehe K, et al. Effect of layer thickness on the elution of bulk-fill composite components. Dent Mater. 2017;33:54-62 pubmed publisher
    ..The composites ELS Bulk fill, SDR Bulk fill and Venus Bulkfill were polymerized according to the instruction of the manufacturers...
  60. Mondal A, Banerjee P, Somkuwar A. Enhancement of lung sounds based on empirical mode decomposition and Fourier transform algorithm. Comput Methods Programs Biomed. 2017;139:119-136 pubmed publisher
    ..Our method gives cross correlation index (CCI) of 0.9488, signal to deviation ratio (SDR) of 9.8262, and normalized maximum amplitude error (NMAE) of 26.94 for 0?dB SNR value.
  61. Ahoba Sam C, Boodhoo K, Olsbye U, Jens K. Tailoring Cu Nanoparticle Catalyst for Methanol Synthesis Using the Spinning Disk Reactor. Materials (Basel). 2018;11: pubmed publisher
    ..The spinning disk reactor (SDR), which operates based on shear effect and plug flow in thin films, can be used to rapidly micro-mix reactants in ..
  62. Ozyurek T, Ülker Ö, Demiryürek E, Yilmaz F. The Effects of Endodontic Access Cavity Preparation Design on the Fracture Strength of Endodontically Treated Teeth: Traditional Versus Conservative Preparation. J Endod. 2018;44:800-805 pubmed publisher
    ..using traditional endodontic cavity (TEC) and conservative endodontic cavity (CEC) methods and restored using SDR (Dentsply Caulk, Milford, DE) and EverX Posterior (GC Dental, Tokyo, Japan) base composite materials...
  63. Kamalak H, Kamalak A, Taghizadehghalehjoughi A, Hacimuftuoglu A, Nalcı K. Cytotoxic and biological effects of bulk fill composites on rat cortical neuron cells. Odontology. 2018;106:377-388 pubmed publisher
    ..The study group included five different bulk-fill flow able composites; Surefil SDR Flow, X-tra Base Flow, Venus Bulk Flow, Filtek Bulk Flow and Tetric-Evo Flow...
  64. Paolone M, Kaitsas R, Obach P, Kaitsas V, Benedicenti S, Sorrenti E, et al. Tensile test and interface retention forces between wires and composites in lingual fixed retainers. Int Orthod. 2015;13:210-20 pubmed publisher
    ..022″ Ormco); and three composites: two micro-hybrids (Micro-Hybrid Enamel Plus HFO Micerium, and Micro-Hybrid SDR U Dentsply) and a micro-nano-filled composite (Micro-Nano-Filled Transbond LR 3M)...
  65. Wang Y, Ying B, Chen M, Shen W, Liu Z, Zheng Y. An NADPH-dependent Lactobacillus composti short-chain dehydrogenase/reductase: characterization and application to (R)-1-phenylethanol synthesis. World J Microbiol Biotechnol. 2017;33:144 pubmed publisher
    A new anti-Prelog short-chain dehydrogenase/reductase (SDR) encoding gene lcsdr was cloned from Lactobacillus composti DSM 18527, and heterologously expressed in Escherichia coli...
  66. Sheppard A, Chen G, Manohar S, Ding D, Hu B, Sun W, et al. Prolonged low-level noise-induced plasticity in the peripheral and central auditory system of rats. Neuroscience. 2017;359:159-171 pubmed publisher
    ..16 channel electrodes were used to measure the local field potentials (LFP) and multi-unit spike discharge rates (SDR) from the IC immediately after and one-week post-exposure...
  67. Almekkawy M, McMahon D, Alqarni H, Jiayu He -. Optimization of transcostal phased-array refocusing using sparse semidefinite relaxation method. Conf Proc IEEE Eng Med Biol Soc. 2017;2017:1449-1452 pubmed publisher
    ..method builds on the limited power deposition (LPD) method, which took advantage of the semidefinite relaxation (SDR) method to relax nonconvex constraints into convex form...
  68. Gambin Y, Ariotti N, McMahon K, Bastiani M, Sierecki E, Kovtun O, et al. Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. elife. 2013;3:e01434 pubmed publisher
    ..cavin family members, single-molecule analysis reveals an exquisite specificity of interactions between cavin1, cavin2 and cavin3...
  69. Fork C, Hitzel J, Nichols B, Tikkanen R, Brandes R. Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells. Basic Res Cardiol. 2014;109:439 pubmed publisher
    ..Collectively, these data suggest that interaction between flotillin-1 and caveolin-1 may facilitate the transport of TLR3-ligands to its intracellular receptor and enables inflammatory TLR3 signaling. ..
  70. Kashio S, Obata F, Miura M. How tissue damage MET metabolism: Regulation of the systemic damage response. Fly (Austin). 2017;11:27-36 pubmed publisher
    ..required for tissue repair in Drosophila wing discs, thus highlighting the importance of systemic damage response (SDR) in tissue repair...
  71. Gallo F, Caprioglio A, Castagno R, Ronco G, Segnan N, Giordano L. Inequalities in cervical cancer screening utilisation and results: A comparison between Italian natives and immigrants from disadvantaged countries. Health Policy. 2017;121:1072-1078 pubmed publisher
    ..43 vs OR=1.04). The Standardised Detection Ratio (SDR) suggested a frequency of severe lesions nearly double among immigrants in first screens (SDR=1.94; 95% CI: 1.82-2...
  72. Saracyn M, Czarzasta K, Brytan M, Murawski P, Lewicki S, Zabkowski T, et al. Role of Nitric Oxide Pathway in Development and Progression of Chronic Kidney Disease in Rats Sensitive and Resistant to its Occurrence in an Experimental Model of 5/6 Nephrectomy. Med Sci Monit. 2017;23:4865-4873 pubmed
    ..MATERIAL AND METHODS Two rat strains were used: Wistar (WR) and Sprague-Dawley rats (SDR) in a model of CKD - 5/6 nephrectomy...
  73. Kisiela M, Faust A, Ebert B, Maser E, Scheidig A. Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans. FEBS J. 2017;: pubmed publisher
    The human dehydrogenase/reductase SDR family member 4 (DHRS4) is a tetrameric protein that is involved in the metabolism of several aromatic carbonyl compounds, steroids and bile acids...
  74. Karacolak G, Türkün L, Boyacioglu H, Ferracane J. Influence of increment thickness on radiant energy and microhardness of bulkfill resin composites. Dent Mater J. 2017;: pubmed publisher
    ..For groups of Aura 2 mm, X-tra Fil 2 and 4 mm, SDR 2 and 4 mm, X-tra Base 2 mm no significant difference was found between top and bottom microhardness...
  75. Medvedeva N, Kazakova O, Lopatina T, Smirnova I, Giniyatullina G, Baikova I, et al. Synthesis and antimycobacterial activity of triterpeni? A-ring azepanes. Eur J Med Chem. 2018;143:464-472 pubmed publisher
    ..tuberculosis (MTB) H37Rv and SDR-TB in the National Institute of Allergy and Infectious Diseases...
  76. Nogami H, Watanabe T, Kobayashi S. IGF-I and IGF-binding protein gene expressions in spontaneous dwarf rat. Am J Physiol. 1994;267:E396-401 pubmed
    ..factor I (IGF-I) and IGF-I-binding protein (IGFBP)-1, -2, -3, and -4 were examined in spontaneous dwarf rats (SDR), which completely and specifically lack GH among pituitary hormones...
  77. Jing W, Luo P, Zhu M, Ai Q, Chai H, Tu J. Prognostic and Diagnostic Significance of SDPR-Cavin-2 in Hepatocellular Carcinoma. Cell Physiol Biochem. 2016;39:950-60 pubmed publisher
    ..9%) for detecting HCC with the serum α‑fetoprotein (AFP) levels below 200 ng/ml from those hepatitis B and cirrhosis cases. Our data suggested that cavin-2 might be considered as a potential prognostic and diagnostic indicator in HCC. ..
  78. Exposito A, Patterson D, Mansor W, Monteagudo J, Emanuelsson E, Sanmartín I, et al. Antipyrine removal by TiO2 photocatalysis based on spinning disc reactor technology. J Environ Manage. 2017;187:504-512 pubmed publisher
    ..the emerging contaminant antipyrine (AP) was studied and optimized in a novel photocatalytic spinning disc reactor (SDR). A heterogeneous process (UV/H2O2/TiO2) was used...
  79. Sitthinamsuwan B, Phonwijit L, Khampalikit I, Nitising A, Nunta aree S, Suksompong S. Comparison of efficacy between dorsal root entry zone lesioning and selective dorsal rhizotomy for spasticity of cerebral origin. Acta Neurochir (Wien). 2017;159:2421-2430 pubmed publisher
    ..study has compared efficacy between dorsal root entry zone lesioning (DREZL) and selective dorsal rhizotomy (SDR) for reduction of spasticity...
  80. D Aquino D, Moussa A, Ammar A, Ingale H, Vloeberghs M. Selective dorsal rhizotomy for the treatment of severe spastic cerebral palsy: efficacy and therapeutic durability in GMFCS grade IV and V children. Acta Neurochir (Wien). 2018;160:811-821 pubmed publisher
    Selective dorsal rhizotomy (SDR) has been established as an effective surgical treatment for spastic diplegia...
  81. Liu J, Cao Z, Zou S, Liu H, Hai X, Wang S, et al. An investigation of the leaf retention capacity, efficiency and mechanism for atmospheric particulate matter of five greening tree species in Beijing, China. Sci Total Environ. 2018;616-617:417-426 pubmed publisher
    ..The experimental leaf samples were collected from trees with similar sizes 4 (SDR) and 14days (LDR) after rainfall...
  82. Rosa J, Cox C, Cancela M, Laizé V. Identification of a fish short-chain dehydrogenase/reductase associated with bone metabolism. Gene. 2018;645:137-145 pubmed publisher
    ..analysis of the deduced protein revealed the presence of domains typical of short-chain dehydrogenase/reductases (SDR)...
  83. Bai L, Deng X, Li Q, Wang M, An W, Deli A, et al. Down-regulation of the cavin family proteins in breast cancer. J Cell Biochem. 2012;113:322-8 pubmed publisher
    ..We report here that the cavin family protein PTRF, SRBC and serum deprivation response protein were down regulated in breast cancer cell lines and breast tumor tissue...
  84. Tiwari A, Mieras L, Dhakal K, Arif M, Dandel S, Richardus J. Introducing leprosy post-exposure prophylaxis into the health systems of India, Nepal and Indonesia: a case study. BMC Health Serv Res. 2017;17:684 pubmed publisher
    ..Exposure Prophylaxis (LPEP) program is ongoing to investigate the feasibility of providing single dose rifampicin (SDR) as post-exposure prophylaxis (PEP) to the contacts of leprosy cases in various health systems...
  85. Motoyama T, Nakano S, Yamamoto Y, Tokiwa H, Asano Y, Ito S. Product Release Mechanism Associated with Structural Changes in Monomeric l-Threonine 3-Dehydrogenase. Biochemistry. 2017;56:5758-5770 pubmed publisher
    A short chain dehydrogenase like l-threonine 3-dehydrogenase (SDR-TDH) from metagenome data (mtTDH) was identified by database mining...
  86. Wang H, Ouyang Y, Zhou C, Xiao D, Guo Y, Wu L, et al. YKL071W from Saccharomyces cerevisiae encodes a novel aldehyde reductase for detoxification of glycolaldehyde and furfural derived from lignocellulose. Appl Microbiol Biotechnol. 2017;101:8405-8418 pubmed publisher
    ..cerevisiae encodes a novel "classical" short-chain dehydrogenase/reductase (SDR) protein with NADH-dependent enzymatic activities for reduction of furfural (FF), glycolaldehyde (GA), formaldehyde ..
  87. Barnes C, Krzywda E, Lahiff S, McDowell D, Christians K, Knechtges P, et al. Development of a high risk pancreatic screening clinic using 3.0 T MRI. Fam Cancer. 2018;17:101-111 pubmed publisher
    ..for screening included the presence of PC in: ≥ 2 first degree relatives (FDR), 1 FDR and 1 s degree relative (SDR), ≥ 3 any degree relatives (ADR), or any known hereditary cancer syndrome with increased PC risk. Imaging with 3...
  88. Sasaki H, Tangkaratt V, Niu G, Sugiyama M. Sufficient Dimension Reduction via Direct Estimation of the Gradients of Logarithmic Conditional Densities. Neural Comput. 2018;30:477-504 pubmed publisher
    Sufficient dimension reduction (SDR) is aimed at obtaining the low-rank projection matrix in the input space such that information about output data is maximally preserved...
  89. Gholampour A, Sakhaei S, Andargoli S. A robust approach to apodization design in phased arrays for ultrasound imaging. Ultrasonics. 2017;76:10-18 pubmed publisher
    ..Furthermore, the optimization problem is reformulated as a convex problem using semidefinite relaxation (SDR) method to be solved more efficiently...
  90. Malátková P, Skarka A, Musilova K, Wsol V. Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes. Chem Biol Interact. 2017;276:121-126 pubmed publisher
    ..Next, a panel of recombinant carbonyl reducing enzymes from AKR and SDR superfamilies has been studied to find the enzymes responsible for the cytosolic reduction of tiaprofenic acid...
  91. Yeh Y, Chen C, Tseng H, Wang H, Tsai H, Lin N, et al. Enlarging vascular stents after pediatric liver transplantation. J Pediatr Surg. 2017;52:1934-1939 pubmed publisher
    ..Morphologic changes of stents were assessed from plain films by a new index: the stent diameter ratio (SDR). The median age of the patients at LT was 8.9 months...
  92. Yu S, Li H, Lu Y, Zheng G. A Catalyst from Burkholderia cenocepacia for Efficient Anti-Prelog's Bioreduction of 3,5-Bis(Trifluoromethyl) Acetophenone. Appl Biochem Biotechnol. 2018;184:1319-1331 pubmed publisher
    ..a genome mining approach, an NADPH-dependent short-chain dehydrogenases derived from Burkholderia cenocepacia (Bc-SDR) was discovered with excellent anti-Prelog's stereoselectivity of reducing 3, 5-bis(trifluoromethyl) acetophenone...