Gene Symbol: catalase
Description: catalase
Alias: catalase
Species: human
Products:     catalase

Top Publications

  1. Jiang Z, Akey J, Shi J, Xiong M, Wang Y, Shen Y, et al. A polymorphism in the promoter region of catalase is associated with blood pressure levels. Hum Genet. 2001;109:95-8 pubmed
    b>Catalase is an important antioxidant enzyme that detoxifies H2O2 into oxygen and water and thus limits the deleterious effects of reactive oxygen species (ROS)...
  2. Casp C, She J, McCormack W. Genetic association of the catalase gene (CAT) with vitiligo susceptibility. Pigment Cell Res. 2002;15:62-6 pubmed
    ..We report here case-control and family-based association studies for the catalase gene (CAT) in vitiligo patients...
  3. Christiansen L, Petersen H, Bathum L, Frederiksen H, McGue M, Christensen K. The catalase -262C/T promoter polymorphism and aging phenotypes. J Gerontol A Biol Sci Med Sci. 2004;59:B886-9 pubmed
    A low level of the central antioxidant enzyme catalase has been suggested to be a risk factor for diseases influenced by oxidative stress...
  4. Mak J, Ho S, Yu W, Choo K, Chu C, Yew W, et al. Polymorphisms and functional activity in superoxide dismutase and catalase genes in smokers with COPD. Eur Respir J. 2007;30:684-90 pubmed
    ..dismutase (Mn-SOD) and the cytosine to thymidine transition of nucleotide -262 (-262C>T) polymorphism of the catalase gene, and the activity of erythrocyte SOD and catalase...
  5. Kittur S, Hoppener J, Antonarakis S, Daniels J, Meyers D, Maestri N, et al. Linkage map of the short arm of human chromosome 11: location of the genes for catalase, calcitonin, and insulin-like growth factor II. Proc Natl Acad Sci U S A. 1985;82:5064-7 pubmed
    ..We have now added three other genes, those for catalase, calcitonin, and insulin-like growth factor II (IGF-II), to this map of chromosome 11p by use of restriction site ..
  6. Chistiakov D, Savost anov K, Turakulov R, Titovich E, Zilberman L, Kuraeva T, et al. A new type 1 diabetes susceptibility locus containing the catalase gene (chromosome 11p13) in a Russian population. Diabetes Metab Res Rev. 2004;20:219-24 pubmed
    ..This, therefore suggests that genes encoding catalase and other antioxidant enzymes may implicate in the development of type 1 diabetes...
  7. Cebrian A, Pharoah P, Ahmed S, Smith P, Luccarini C, Luben R, et al. Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. Cancer Res. 2006;66:1225-33 pubmed
    ..Even if confirmed, these four alleles would account for just 0.32% of the excess familial risk of breast cancer. ..
  8. Pask R, Cooper J, Walker N, Nutland S, Hutchings J, Dunger D, et al. No evidence for a major effect of two common polymorphisms of the catalase gene in type 1 diabetes susceptibility. Diabetes Metab Res Rev. 2006;22:356-60 pubmed
    ..Two single nucleotide polymorphisms (SNPs) in the catalase gene have been reported to be associated with T1D...
  9. Park H, Ha E, Uhm Y, Jin S, Kim Y, Chung J, et al. Association study between catalase gene polymorphisms and the susceptibility to vitiligo in Korean population. Exp Dermatol. 2006;15:377-80 pubmed
    ..Reactive oxygen species play an important role in the physiology of cell damage, and catalase is known to regulate oxidative stress...

More Information

Publications105 found, 100 shown here

  1. Gavalas N, Akhtar S, Gawkrodger D, Watson P, Weetman A, Kemp E. Analysis of allelic variants in the catalase gene in patients with the skin depigmenting disorder vitiligo. Biochem Biophys Res Commun. 2006;345:1586-91 pubmed
    ..and consequently damage to pigment cells have been reported in the skin of vitiligo patients, including low catalase activity and increases in hydrogen peroxide levels...
  2. Em S, Laddha N, Chatterjee S, Gani A, Malek R, Shah B, et al. Association of catalase T/C exon 9 and glutathione peroxidase codon 200 polymorphisms in relation to their activities and oxidative stress with vitiligo susceptibility in Gujarat population. Pigment Cell Res. 2007;20:405-7 pubmed
  3. Islam T, McConnell R, Gauderman W, Avol E, Peters J, Gilliland F. Ozone, oxidant defense genes, and risk of asthma during adolescence. Am J Respir Crit Care Med. 2008;177:388-95 pubmed
    ..cardinal feature of asthma, the roles of oxidant air pollutants and antioxidant genes heme oxygenase 1 (HMOX-1), catalase (CAT), and manganese superoxide dismutase (MNSOD) in asthma pathogenesis have yet to be determined...
  4. Polonikov A, Ivanov V, Solodilova M, Kozhuhov M, Panfilov V. Tobacco smoking, fruit and vegetable intake modify association between -21A>T polymorphism of catalase gene and risk of bronchial asthma. J Asthma. 2009;46:217-24 pubmed publisher
    ..The present study was conducted to investigate whether two common polymorphisms -21A > T and -262C > T of catalase (CAT) gene are associated with susceptibility to asthma in a Russian population and to test the hypothesis that ..
  5. Wenten M, Gauderman W, Berhane K, Lin P, Peters J, Gilliland F. Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Am J Epidemiol. 2009;170:1494-501 pubmed publisher
    The individual effect of functional single nucleotide polymorphisms within the catalase and myeloperoxidase genes (CAT and MPO) has been studied in relation to asthma; however, their interrelationship with ambient air pollution exposures ..
  6. Tang H, Dong X, Day R, Hassan M, Li D. Antioxidant genes, diabetes and dietary antioxidants in association with risk of pancreatic cancer. Carcinogenesis. 2010;31:607-13 pubmed publisher
    ..polymorphisms (SNPs) of genes coding for superoxide dismutase (SOD) 2, glutathione S-transferase alpha 4 (GSTA4), catalase and glutathione peroxidase in 575 patients with pancreatic adenocarcinoma and 648 healthy controls in a case-..
  7. Bulut H, Pehlivan M, Alper S, Tomatir A, Onay H, Yüksel S, et al. Lack of association between catalase gene polymorphism (T/C exon 9) and susceptibility to vitiligo in a Turkish population. Genet Mol Res. 2011;10:4126-32 pubmed publisher
    Accumulation of hydrogen peroxide (H(2)O(2)) and low catalase (CAT) activity have been demonstrated in the epidermis of vitiligo patients...
  8. Akbas H, Dertlioglu S, Dilmec F, Balkan M. No association between catalase (CAT) gene polymorphisms and susceptibility to vitiligo in a Turkish population. Clin Ter. 2013;164:e173-7 pubmed publisher
    ..Low catalase (CAT) activity and Accumulation of hydrogen peroxide (H2O2) have been demonstrated in the epidermis of vitiligo ..
  9. Shaffer J, Preston K. Molecular analysis of an acatalasemic mouse mutant. Biochem Biophys Res Commun. 1990;173:1043-50 pubmed
    The Csb acatalasemia mouse mutant differentially expresses reduced levels of catalase activity in a tissue specific manner...
  10. Forsberg L, Lyrenäs L, de Faire U, Morgenstern R. A common functional C-T substitution polymorphism in the promoter region of the human catalase gene influences transcription factor binding, reporter gene transcription and is correlated to blood catalase levels. Free Radic Biol Med. 2001;30:500-5 pubmed
    ..genetic tools that can be used to determine the potential impact of oxidative stress we examined the human catalase gene promoter for possible variation...
  11. Young R, Hopkins R, Black P, Eddy C, Wu L, Gamble G, et al. Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function. Thorax. 2006;61:394-9 pubmed
    ..determine whether genetic variants within genes encoding the antioxidant enzymes superoxide dismutase (SOD) and catalase may be associated with the development of impaired lung function...
  12. Lin S, Shyue S, Shih M, Chu T, Chen Y, Ku H, et al. Superoxide dismutase and catalase inhibit oxidized low-density lipoprotein-induced human aortic smooth muscle cell proliferation: role of cell-cycle regulation, mitogen-activated protein kinases, and transcription factors. Atherosclerosis. 2007;190:124-34 pubmed
    Several antioxidant enzymes, including copper, zinc-superoxide dismutase (Cu, Zn-SOD) and catalase, have been suggested to be protective against the proliferation of vascular smooth muscle cells exposed to oxidative stress...
  13. Flekac M, Skrha J, Hilgertova J, Lacinova Z, Jarolimkova M. Gene polymorphisms of superoxide dismutases and catalase in diabetes mellitus. BMC Med Genet. 2008;9:30 pubmed publisher
  14. Quick S, Shields P, Nie J, Platek M, McCann S, Hutson A, et al. Effect modification by catalase genotype suggests a role for oxidative stress in the association of hormone replacement therapy with postmenopausal breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2008;17:1082-7 pubmed publisher
    b>Catalase, a ubiquitous heme enzyme, catalyzes conversion of hydrogen peroxide to water and molecular oxygen, protecting cells from oxidative stress...
  15. Rajaraman P, Hutchinson A, Rothman N, Black P, Fine H, Loeffler J, et al. Oxidative response gene polymorphisms and risk of adult brain tumors. Neuro Oncol. 2008;10:709-15 pubmed publisher
    ..6; 95% CI, 0.3-1.0). These relationships persisted when major groups of disease controls were excluded from the analysis. Our results suggest that common variants in the SOD2, SOD3, and CAT genes may influence brain tumor risk. ..
  16. Liu L, Li C, Gao J, Li K, Zhang R, Wang G, et al. Promoter variant in the catalase gene is associated with vitiligo in Chinese people. J Invest Dermatol. 2010;130:2647-53 pubmed publisher
    ..Reduced catalase enzyme activity and accumulation of excessive hydrogen peroxide have been observed in vitiligo...
  17. Lv Y, Liao W, Luan Q, Wang H, Wang L, Li Q. The polymorphism of catalase T/C codon 389 in exon 9 and vitiligo susceptibility: a meta-analysis. J Eur Acad Dermatol Venereol. 2011;25:955-8 pubmed publisher
    ..It has been described that some polymorphisms in the catalase (CAT) gene may affect the risk of vitiligo. However, the results were inconsistent...
  18. Singh D, Arya P, Sharma A, Dobhal M, Gupta R. Modulatory potential of α-amyrin against hepatic oxidative stress through antioxidant status in Wistar albino rats. J Ethnopharmacol. 2015;161:186-93 pubmed publisher
    ..vitamin C and vitamin E in serum concomitantly with the hepatic-antioxidants like superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glutathione-s-transferase (GST), and 5´-..
  19. Li C, Li L, Yang C, Zhong Y, Wu D, Shi L, et al. Hepatoprotective effects of Methyl ferulic acid on alcohol-induced liver oxidative injury in mice by inhibiting the NOX4/ROS-MAPK pathway. Biochem Biophys Res Commun. 2017;493:277-285 pubmed publisher
    ..MFA markedly increased levels of superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GSH-Px) and total antioxidative capacity (T-AOC), and reduced ..
  20. Tian M, Liu F, Liu H, Zhang Q, Li L, Hou X, et al. Grape seed procyanidins extract attenuates Cisplatin-induced oxidative stress and testosterone synthase inhibition in rat testes. Syst Biol Reprod Med. 2018;64:246-259 pubmed publisher
    ..anion; H2O2: hydrogen peroxide; •OH: hydroxyl radicals; SOD: superoxide dismutase; CAT: catalase; GSH-Px: glutathione peroxidase; LPO: lipid peroxidation; 8-OHdG: 8-hydroxy-2-deoxyguanosine; HO-1: heme ..
  21. Zhong W, Qian K, Xiong J, Ma K, Wang A, Zou Y. Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-?B related signaling. Biomed Pharmacother. 2016;83:302-313 pubmed publisher
    ..AST) and alkaline phosphatase (ALP), accelerated liver antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) and glutathione peroxidase (GSH-px) levels, and inhibited activation of the mitogen-..
  22. Das M, Basu S, Banerjee B, Sen A, Jana K, Datta G. Hepatoprotective effects of green Capsicum annum against ethanol induced oxidative stress, inflammation and apoptosis in rats. J Ethnopharmacol. 2018;227:69-81 pubmed publisher
    ..p.) for 30 days. Lipid peroxidation (LPO) and reduced glutathione content (GSH) in tissue homogenate, along with catalase (CAT), superoxide dismutase (Cu-Zn-SOD & Mn-SOD), glutathione peroxidase (GPx), glutathione reductase (GR), ..
  23. Batool R, Rashid Khan M, Ahmed Zai J, Ali S, Maryam S, Naz I, et al. Brachychiton populneus (Schott & Endl.) R.Br. ameliorate carbon tetrachloride induced oxidative stress through regulation of endoplasmic reticulum stress markers and inflammatory mediators in Sprague-Dawley male rats. Biomed Pharmacother. 2018;107:1601-1610 pubmed publisher
    ..Administration of CCl4 to rat decreased (p < 0.01) the level of catalase (CAT), total superoxide dismutase (SOD), peroxidase (POD), soluble protein and reduced glutathione (GSH) whereas ..
  24. Elmallah M, Elkhadragy M, Al Olayan E, Abdel Moneim A. Protective Effect of Fragaria ananassa Crude Extract on Cadmium-Induced Lipid Peroxidation, Antioxidant Enzymes Suppression, and Apoptosis in Rat Testes. Int J Mol Sci. 2017;18: pubmed publisher
    ..Considering cadmium toxicity, the level of the antioxidant enzyme activities including catalase (CAT), superoxide dismutase (SOD2), glutathione peroxidase (GPx1), and glutathione reductase (GR) were markedly ..
  25. Banerjee S, Aykin Burns N, Krager K, Shah S, Melnyk S, Hauer Jensen M, et al. Loss of C/EBPδ enhances IR-induced cell death by promoting oxidative stress and mitochondrial dysfunction. Free Radic Biol Med. 2016;99:296-307 pubmed publisher
    ..of wild type (WT) and KO MEFs with polyethylene glycol-conjugated Cu-Zn superoxide dismutase (PEG-SOD) and catalase (PEG-CAT) combination prior to irradiation showed a partial rescue of clonogenic survival, thus demonstrating a ..
  26. Katsukawa C, Umeda K, Inamori I, Kosono Y, Tanigawa T, Komiya T, et al. Toxigenic Corynebacterium ulcerans isolated from a wild bird (ural owl) and its feed (shrew-moles): comparison of molecular types with human isolates. BMC Res Notes. 2016;9:181 pubmed publisher
    ..ulcerans isolates from dogs and a cat, which are known to serve as sources for human infection. The findings suggest that the shrew-mole may be a potential reservoir of a zoonotic pathogen C. ulcerans. ..
  27. Mert T, Oksuz H, Tugtag B, Kilinc M, Sahin E, Altun İ. Anti-hypernociceptive and anti-oxidative effects of locally treated dobutamine in diabetic rats. Pharmacol Rep. 2015;67:1016-23 pubmed publisher
    ..showed significant increased malondialdehyde (MDA), nitric oxide (NO) and decreased superoxide dismutase (SOD), catalase (CAT), myeloperoxidase (MPO) in the paw...
  28. Horváthová F, Danielisova V, Domoráková I, Solar P, Rybarova S, Hodorová I, et al. The effect of R-(-)-deprenyl administration on antioxidant enzymes in rat testis. Eur J Pharmacol. 2016;788:21-28 pubmed publisher
    ..the effect of R-(-)-deprenyl administration on the activity and localization of superoxide dismutases (SODs) and catalase (CAT) in rat testis...
  29. Carbajal Hernández A, Valerio García R, Martínez Ruíz E, Jarquín Díaz V, Martínez Jerónimo F. Maternal-embryonic metabolic and antioxidant response of Chapalichthys pardalis (Teleostei: Goodeidae) induced by exposure to 3,4-dichloroaniline. Environ Sci Pollut Res Int. 2017;24:17534-17546 pubmed publisher
    ..We assessed the activity of antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), macromolecules content (proteins, lipids, carbohydrates), glucose, and ..
  30. Zhou W, Lin J, Wang S, Lin H. [Effect of Herba Scutellariae Barbatae flavonoids in delaying aging of Caenorhabditis elegans and human umbilical vein endothelial cells in vitro]. Nan Fang Yi Ke Da Xue Xue Bao. 2017;37:821-826 pubmed
    ..HF also may protect endothelial cells against oxidative damage. ..
  31. Karabencheva Christova T, Christov C, Fields G. Collagenolytic Matrix Metalloproteinase Structure-Function Relationships: Insights From Molecular Dynamics Studies. Adv Protein Chem Struct Biol. 2017;109:1-24 pubmed publisher
    ..Ultimately, the MD simulation studies have complemented structural (NMR spectroscopy, X-ray crystallography) and kinetic analyses to provide a more detailed mechanistic view of MMP-catalyzed collagenolysis. ..
  32. Per S, Kose M, Ozdemir A, Pandir D. Hepatoprotective effects of capping protein gelsolin against hyperoxia-induced hepatotoxicity, oxidative stress and DNA damage in neonatal rats. Environ Toxicol Pharmacol. 2018;58:189-195 pubmed publisher
    ..Based on these findings, gelsolin restored these changing to near normal levels but it does not protect completely in the hyperoxia conditions. ..
  33. Lynch S, Wood R, Boushey H, Bacharier L, Bloomberg G, Kattan M, et al. Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014;134:593-601.e12 pubmed publisher
    ..These findings suggest that concomitant exposure to high levels of certain allergens and bacteria in early life might be beneficial and suggest new preventive strategies for wheezing and allergic diseases. ..
  34. Priborsky J, Stara A, Rezabek J, Zuskova E, Lepic P, Velisek J. Comparison of the effect of four anaesthetics on haematological profiles, oxidative stress and antioxidant enzymes in barbel (Barbus barbus). Neuro Endocrinol Lett. 2015;36 Suppl 1:141-6 pubmed
    ..01) in Propiscin (10 min). The activity of catalase (CAT) was significantly increased (p<0.05) in the muscle 24 h after all anaesthetics...
  35. Song S, Yang L, Ye M, Chen X, Shi F, Shaikh F. Antioxidant activity of a Lachnum YM226 melanin-iron complex and its influence on cytokine production in mice with iron deficiency anemia. Food Funct. 2016;7:1508-14 pubmed publisher
    ..treatment with LM-Fe significantly increased the antioxidant enzyme activities of superoxidase dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) in plasma to normal or better...
  36. Costa L, Mohmood I, Trindade T, Anjum N, Duarte A, Pereira E. Phagocytic cell responses to silica-coated dithiocarbamate-functionalized iron oxide nanoparticles and mercury co-exposures in Anguilla anguilla L. Environ Sci Pollut Res Int. 2016;23:12272-86 pubmed publisher
    ..major enzymatic- (glutathione reductase, GR; glutathione peroxidase, GPX; glutathione sulfo-transferase, GST; catalase, CAT) and thiol- (non-protein thiols, NP-SH; total glutathione, TGSH)-based defense biomarkers, this study ..
  37. Ogunyinka B, Oyinloye B, Osunsanmi F, Opoku A, Kappo A. Protective Effects of Parkia biglobosa Protein Isolate on Streptozotocin-Induced Hepatic Damage and Oxidative Stress in Diabetic Male Rats. Molecules. 2017;22: pubmed publisher
    ..AST), total protein, total glutathione (Total GSH), glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), and interleukin-6 (IL-6) activities. Histology of liver sections was also performed...
  38. Liu L, Fang C, Yang J, Zhang H, Huang Y, Xuan C, et al. The effect of noise exposure on insulin sensitivity in mice may be mediated by the JNK/IRS1 pathway. Environ Health Prev Med. 2018;23:6 pubmed publisher
    ..Impaired insulin sensitivity in noise-exposed mice might be mediated by an enhancement of the JNK/IRS1 pathway. Inflammation and oxidative stress might contribute to insulin resistance after chronic noise exposure. ..
  39. Hurteau M, Thibaudier Y, Dambreville C, Danner S, Rybak I, Frigon A. Intralimb and Interlimb Cutaneous Reflexes during Locomotion in the Intact Cat. J Neurosci. 2018;38:4104-4122 pubmed publisher
    ..The comparatively stronger descending pathways from cervical to lumbar circuits controlling the forelimbs and hindlimbs, respectively, could serve a protective function. ..
  40. Jiang W, Tang R, Liu Y, Kuang S, Jiang J, Wu P, et al. Manganese deficiency or excess caused the depression of intestinal immunity, induction of inflammation and dysfunction of the intestinal physical barrier, as regulated by NF-κB, TOR and Nrf2 signalling, in grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2015;46:406-16 pubmed publisher
    ..90 and 8.99 mg kg(-1) diet, respectively. ..
  41. Eloy Y, Vasconcelos I, Barreto A, Freire Filho F, Oliveira J. H2O2 plays an important role in the lifestyle of Colletotrichum gloeosporioides during interaction with cowpea [Vigna unguiculata (L.) Walp]. Fungal Biol. 2015;119:747-57 pubmed publisher
    ..primary leaves of cowpea were excised, infiltrated with salicylic acid (SA), glucose oxidase + glucose (GO/G), catalase (CAT) or diphenyliodonium chloride (DPI), followed by spore inoculation on the adaxial leaf surface...
  42. Araki M, Ohshima N, Aso C, Konishi A, Obinata H, Tatei K, et al. Enzymatic characterization of recombinant rat DDHD2: a soluble diacylglycerol lipase. J Biochem. 2016;160:269-279 pubmed
    ..These results therefore support the idea that DDHD2 functions as a DG lipase in vivo and produces 2-AG. ..
  43. Carbotta G, Tartaglia F, Giuliani A, Carbotta S, Tromba L, Jacomelli I, et al. Cardiovascular risk in chronic autoimmune thyroiditis and subclinical hypothyroidism patients. A cluster analysis. Int J Cardiol. 2017;230:115-119 pubmed publisher
    ..Confirmation of these results in larger series of patients could justify hormone therapy for prevention of CHD in these thyroid patients versus placebo treatment. ..
  44. Buisson Y. [Control of Opisthorchis viverrini infection for cholangiocarcinoma prevention]. Bull Soc Pathol Exot. 2017;110:61-67 pubmed publisher
  45. Zhao B, Zhou L, Ma L, He Y, Gao J, Li D, et al. Co-immobilization of glucose oxidase and catalase in silica inverse opals for glucose removal from commercial isomaltooligosaccharide. Int J Biol Macromol. 2018;107:2034-2043 pubmed publisher
    In this work, glucose oxidase (GOD) and catalase (CAT) were co-immobilized on novel silica inverse opals (IO-SiO2) through sol-gel process...
  46. Koenig A, Cooper T, Greene C, Sharma A, Sakamoto K. Clinical Salmonellosis in a Closed Colony of Blood Donor Cats. Comp Med. 2017;67:524-528 pubmed
    ..This case report highlights the potential for unlikely infections to occur, even in a closed colony of research animals, as well as the important role of sanitation in the elimination of this enteric pathogen. ..
  47. Lohmann C, Gabler B, Kroher G, Spiegel D, Linde H, Reischl U. Disciforme keratitis caused by Bartonella henselae: an unusual ocular complication in cat scratch disease. Eur J Ophthalmol. 2000;10:257-8 pubmed
    ..With the use of the 16S rDNA-PCR technique with subsequent DANN sequencing on corneal material obtained by corneal scrape we were able to identify Bartonella henselae in an unusual form of disciforme keratitis...
  48. Taschetto L, Scaini G, Zapelini H, Ramos A, Strapazzon G, Andrade V, et al. Acute and long-term effects of intracerebroventricular administration of ?-ketoisocaproic acid on oxidative stress parameters and cognitive and noncognitive behaviors. Metab Brain Dis. 2017;32:1507-1518 pubmed publisher
    ..From the biochemical and behavioral findings, it we presume that KIC provokes oxidative damage, and the persistence of brain oxidative stress is associated with long-term memory impairment and prepulse inhibition. ..
  49. Ausec L, Berini F, Casciello C, Cretoiu M, van Elsas J, Marinelli F, et al. The first acidobacterial laccase-like multicopper oxidase revealed by metagenomics shows high salt and thermo-tolerance. Appl Microbiol Biotechnol. 2017;101:6261-6276 pubmed publisher
    ..g., 34% activity preserved at 500 mM NaCl) and in the presence of organic solvents. Remarkably, LacM decolored azo and triphenylmethane dyes, also in the absence of redox mediators. ..
  50. Puffe L, Dittrich K, Klauer K. The influence of the Japanese waving cat on the joint spatial compatibility effect: A replication and extension of Dolk, Hommel, Prinz, and Liepelt (2013). PLoS ONE. 2017;12:e0184844 pubmed publisher
  51. Onishi A, Takano K, Kawase T, Ora H, Kansaku K. Affective Stimuli for an Auditory P300 Brain-Computer Interface. Front Neurosci. 2017;11:522 pubmed publisher
    ..Additionally, an ALS patient achieved 90% online classification accuracy. These results suggest that affective stimuli may be useful for preparing a practical auditory BCI system for patients with disabilities...
  52. Han X, Zhang Y, Wang K, Huang Y, Yang Z, Liu Z. The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO2-induced hepatotoxicity. Oncotarget. 2017;8:65302-65312 pubmed publisher
    ..analyses were conducted to observe morphological changes; Biochemical indexes such as oxidative stress (Catalase (CAT), malonyldialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH), reactive oxygen species (ROS)), ..
  53. Rok J, Wrześniok D, Beberok A, Otręba M, Delijewski M, Buszman E. Phototoxic effect of oxytetracycline on normal human melanocytes. Toxicol In Vitro. 2018;48:26-32 pubmed publisher
    ..The obtained results suggest that phototoxicity of oxytetracycline towards normal human melanocytes depends on both time of UVA exposure and the drug concentration. ..
  54. Akinola O, Biliaminu S, Adediran R, Adeniye K, Abdulquadir F. Characterization of prefrontal cortex microstructure and antioxidant status in a rat model of neurodegeneration induced by aluminium chloride and multiple low-dose streptozotocin. Metab Brain Dis. 2015;30:1531-6 pubmed publisher
    ..cortex was homogenized in phosphate buffer solution and the supernatants assayed for some antioxidant enzymes (catalase, CAT; superoxide dismutase, SOD; and reduced glutathione, GSH)...
  55. Kinoshita M, Okayama H, Kawamura G, Shigematsu T, Takahashi T, Miyoshi T, et al. A calcified amorphous tumor that developed on both sides of the atrioventricular valve annulus. J Echocardiogr. 2015;13:148-50 pubmed publisher
    ..Surgery was performed on the 14th day after hospital admission. The patient underwent mitral valve replacement, tricuspid annuloplasty, and tumor resection. Based on the pathological findings, the cardiac tumor was diagnosed as a CAT. ..
  56. Gonçalves Schemitt E, Raskopf Colares J, Minuzzo Hartmann R, Morgan Martins M, Marroni C, Tuñón M, et al. [In Process Citation]. Nutr Hosp. 2016;33:92 pubmed publisher
    ..Conclusión: la glutamina ha demostrado tener efectos protectores contra el daño hepático en un modelo de IHF inducida por TAA en la rata. ..
  57. Chunhua M, Long H, Zhu W, Liu Z, Jie R, Zhang Y, et al. Betulin inhibited cigarette smoke-induced COPD in mice. Biomed Pharmacother. 2017;85:679-686 pubmed publisher
    ..Besides, BE could restore the activities of superoxide dismutase (SOD) in serum and in lung, catalase (CAT) in serum and reduce the content of malondialdehyde (MDA) in serum and in lung...
  58. Suliburska J, Skrypnik K, Szulińska M, Kupsz J, Bogdański P. Effect of hypotensive therapy combined with modified diet or zinc supplementation on biochemical parameters and mineral status in hypertensive patients. J Trace Elem Med Biol. 2018;47:140-148 pubmed publisher
    ..protein (CRP), tumor necrosis factor α (TNF-α), nitric oxide (NO), superoxide dismutase (SOD) and catalase (CAT) were assayed in serum...
  59. Alho A, Lima C, Colella V, Madeira de Carvalho L, Otranto D, Cardoso L. Awareness of zoonotic diseases and parasite control practices: a survey of dog and cat owners in Qatar. Parasit Vectors. 2018;11:133 pubmed publisher
    ..These results highlight the need to raise pet owners' awareness towards prophylactic measures to minimize the potential impact of zoonotic diseases on the health of both animals and humans in Qatar. ..
  60. Xu W, Chen D, Chen Q, Liu W. Growth performance, innate immune responses and disease resistance of fingerling blunt snout bream, Megalobrama amblycephala adapted to different berberine-dietary feeding modes. Fish Shellfish Immunol. 2017;68:458-465 pubmed publisher
    ..05) improved superoxide dismutase (SOD) and catalase (CAT) activities. Fish mortality after challenged by Aeromonas hydrophila was decreased...
  61. Pantall A, Hodson Tole E, Gregor R, Prilutsky B. Increased intensity and reduced frequency of EMG signals from feline self-reinnervated ankle extensors during walking do not normalize excessive lengthening. J Neurophysiol. 2016;115:2406-20 pubmed publisher
    ..Possible effects of morphological reorganization of motor units of ankle extensors and altered sensory and central inputs on the changes in myoelectric activity of self-reinnervated SO and LG are discussed. ..
  62. Zschockelt L, Amelkina O, Siemieniuch M, Kowalewski M, Dehnhard M, Jewgenow K, et al. Synthesis and reception of prostaglandins in corpora lutea of domestic cat and lynx. Reproduction. 2016;152:111-26 pubmed publisher
    ..In contrast, expression of PTGFR was evident in nearly all investigated CL of cat and lynxes, implying that luteal regression, e.g. at the end of pregnancy, is triggered by extra-luteal PGF2?. ..
  63. Shahi S, Fokkens L, Houterman P, Rep M. Suppressor of fusion, a Fusarium oxysporum homolog of Ndt80, is required for nutrient-dependent regulation of anastomosis. Fungal Genet Biol. 2016;95:49-57 pubmed publisher
    ..Our data provides further proof for the divergence in the functions of different members Ndt80 family. We propose that Ndt80 homologs mediate responses to nutrient quality and quantity, with specific responses varying between species. ..
  64. Hohendanner F, DeSantiago J, Heinzel F, Blatter L. Dyssynchronous calcium removal in heart failure-induced atrial remodeling. Am J Physiol Heart Circ Physiol. 2016;311:H1352-H1359 pubmed publisher
    ..In summary, HF atrial myocytes show accelerated but dyssynchronous diastolic Ca removal and altered sarcoplasmic reticulum Ca-ATPase (SERCA) and NCX activity that result in increased susceptibility to arrhythmia. ..
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    ..11.1.7), superoxide dismutase (SOD; EC, catalase (CAT; EC, ascorbate peroxidase (APX; EC and NADP-malate dehydrogenase (NADP-MDH; EC1.1.1...
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    ..Activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione-S-transferase (GST) were also measured in the homogenates of in vitro reared honeybee ..
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    ..Our results provide insights into how an unstructured C-tail contributes to DEAD-box protein activity and suggest parallels with other families of RNA- and DNA-binding proteins. ..
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    ..and zymographic analysis to determine the levels of antioxidant enzymes [superoxide dismutase (SOD) and catalase (CAT)], interleukin (IL)-1?, and transforming growth factor (TGF)-?1 and the activities of matrix ..
  70. Hamed H, Abdel Tawwab M. Ameliorative effect of propolis supplementation on alleviating bisphenol-A toxicity: Growth performance, biochemical variables, and oxidative stress biomarkers of Nile tilapia, Oreochromis niloticus (L.) fingerlings. Comp Biochem Physiol C Toxicol Pharmacol. 2017;202:63-69 pubmed publisher
    ..Levels of malondialdehyde (MDA) as well as superoxide dismutase (SOD) and catalase (CAT) activities increased significantly due to BPA exposure, whereas significant reductions in the activity of ..
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    ..Here we examined the effects of catalase (Cat), reduced and oxidized hemoglobin (Hb and metHb), albumin (alb), manganese (III) tetrakis (4-benzoic acid) ..
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    ..Our experimental and computational results allow us to elucidate the underlying mechanism for the ionic effect on PD and the subsequent PT process at the molecular level. ..
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    ..This study offers a simple CTDI-like measurement that can approximate the AAPM [Formula: see text] in clinical CBCT scanners capable of providing four or more scan lengths...
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    ..Various evidence-based CAT methods have been proved to be effective in the management of both acute and chronic pain. Nurses are well placed to implement various CAT modalities. ..
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    ..These data indicate that EAA-mediated synaptic drive to RVLM-spinal sympathoexcitatory neurons accounts for a significant component of their basal activity...
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    ..We also suggest that other species are likely to have a small-celled area of red nucleus projecting to the spinal cord...
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    ..we characterized behavioral and cognitive performance of 5- to 6-month-old mice over-expressing mitochondrial catalase (MCAT)...
  78. Safari R, Hoseinifar S, Van Doan H, Dadar M. The effects of dietary Myrtle (Myrtus communis) on skin mucus immune parameters and mRNA levels of growth, antioxidant and immune related genes in zebrafish (Danio rerio). Fish Shellfish Immunol. 2017;66:264-269 pubmed publisher
    ..These results on zebrafish model also highlights the potential use of Myrtle supplements as additive in human diets. ..
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    ..The results clearly indicated that the Al-MPS could be used as a beneficial health food and potentially natural candidate medicine in preventing the high-fat emulsion-induced hyperlipidemia. ..
  81. Prendergast M, Quintana Morales E, Crowther A, Horton M, Boivin N. Dietary Diversity on the Swahili Coast: The Fauna from Two Zanzibar Trading Locales. Int J Osteoarchaeol. 2017;27:621-637 pubmed publisher
    ..This diversity in early Swahili coast foodways is essential to discussions of the agents engaged in long-distance maritime trade...
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    ..This article is protected by copyright. All rights reserved...
  83. Zabłocka Słowińska K, Płaczkowska S, Prescha A, Pawełczyk K, Porebska I, Kosacka M, et al. Serum and whole blood Zn, Cu and Mn profiles and their relation to redox status in lung cancer patients. J Trace Elem Med Biol. 2018;45:78-84 pubmed publisher
    ..Moreover, the type of biological fluid influences both - alterations in the metal profile and relationships with redox status parameters. ..
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    ..growth hormone altered the degree of lung and liver lipid peroxidation and the activity of glutathione and catalase in lung and liver tissue after burn injury...
  85. Kolusari A, Kurdoglu M, Bugdayci G, Adali E, Yildizhan R, Cebi A, et al. Relationship between erythrocyte catalase and serum adenosine deaminase activities in eclampsia. J Matern Fetal Neonatal Med. 2009;22:321-4 pubmed publisher
    ..status and T-cell activation in the pathogenesis of eclampsia by measuring the activities of erythrocyte catalase, an enzyme of antioxidant mechanism, and serum adenosine deaminase (ADA), regarded as a marker of T-cell ..
  86. Gonçalves A, Hall C, Kowbel D, Glass N, Videira A. CZT-1 is a novel transcription factor controlling cell death and natural drug resistance in Neurospora crassa. G3 (Bethesda). 2014;4:1091-102 pubmed publisher
    ..crassa isolates pointed out genes associated with a cell death role of CZT-1, including catalase-1 (cat-1) and apoptosis-inducing factor-homologous mitochondrion-associated inducer of death 2 (amid-2)...
  87. Kudin A, Baron G, Zsurka G, Hampel K, Elger C, Grote A, et al. Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy. Free Radic Biol Med. 2017;106:270-277 pubmed publisher
    ..The mutant fibroblasts were also found to be less resistant to a hydrogen peroxide challenge. Our data agree with a potential role of insufficient ROS detoxification for disease manifestation in genetic generalized epilepsy. ..
  88. González E, Jiménez M, Hernández S, Martín Martín I, Molina R. Phlebotomine sand fly survey in the focus of leishmaniasis in Madrid, Spain (2012-2014): seasonal dynamics, Leishmania infantum infection rates and blood meal preferences. Parasit Vectors. 2017;10:368 pubmed publisher
    ..These results reinforce the need for an extensive and permanent surveillance in this region, and others of similar characteristics, in order to control the vector and regulate the populations of wild reservoirs. ..
  89. Meachen J. Ancient DNA: Saber-Toothed Cats Are the Same Beasts After All. Curr Biol. 2017;27:R1165-R1167 pubmed publisher
    ..Ancient DNA from the saber-toothed cat Homotherium reveals that the late Pleistocene species from Europe and North America were the same. Homotherium turns out to be only distantly related to the well-known saber-toothed Smilodon...
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  91. Hunt C, Antonopoulou I, Tanksale A, Rova U, Christakopoulos P, Haritos V. Insights into substrate binding of ferulic acid esterases by arabinose and methyl hydroxycinnamate esters and molecular docking. Sci Rep. 2017;7:17315 pubmed publisher
    ..The findings of this study provide a basis for developing a robust classification system for FAE and form the basis of sequence-function relationships for this class. ..
  92. Ando T, Mimura K, Johansson C, Hanson M, Mougiakakos D, Larsson C, et al. Transduction with the antioxidant enzyme catalase protects human T cells against oxidative stress. J Immunol. 2008;181:8382-90 pubmed
    ..In this study, we have evaluated whether enhanced expression of the antioxidant enzyme catalase in human T cells can protect them against reactive oxygen species...