calretinin

Summary

Gene Symbol: calretinin
Description: calbindin 2
Alias: CAB29, CAL2, calretinin, 29 kDa calbindin, calbindin 2, (29kD, calretinin), calbindin D29K, testicular secretory protein Li 8
Species: human

Top Publications

  1. ncbi Selective immunocytochemical localisation of calretinin in the human ovary
    S Bertschy
    Institute of Histology and General Embryology, University of Fribourg, Switzerland
    Histochem Cell Biol 109:59-66. 1998
  2. pmc SV40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis
    Thomas Henzi
    Unit of Anatomy, Department of Medicine, University of Fribourg, Route Albert Gockel 1, CH 1700 Fribourg, Switzerland
    Am J Pathol 174:2324-36. 2009
  3. ncbi Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Semin Diagn Pathol 22:3-32. 2005
  4. doi Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors
    Chengquan Zhao
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 33:354-66. 2009
  5. ncbi [A comparative evaluation of immunohistochemical markers for the differential diagnosis between malignant mesothelioma, non-small cell carcinoma involving the pleura, and benign reactive mesothelial cell proliferation]
    Ewa Szczepulska-Wójcik
    Zakład Patomorfologii Instytutu Gruźlicy i Chorób Płuc w Warszawie
    Pneumonol Alergol Pol 75:57-69. 2007
  6. ncbi Correlation of morphology, electrophysiology and chemistry of neurons in the myenteric plexus of the guinea-pig distal colon
    A E Lomax
    Department of Anatomy, University of Melbourne, Parkville, Victoria, Australia
    J Auton Nerv Syst 76:45-61. 1999
  7. doi Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:1013-21. 2008
  8. ncbi CD10 and calretinin staining of endocervical glandular lesions, endocervical stroma and endometrioid adenocarcinomas of the uterine corpus: CD10 positivity is characteristic of, but not specific for, mesonephric lesions and is not specific for endometrial
    W G McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, UK
    Histopathology 43:144-50. 2003
  9. doi Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates
    Antón Barreiro-Iglesias
    Department of Cell Biology and Ecology, Faculty of Biology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain
    J Comp Neurol 511:438-53. 2008
  10. doi Single-dose and chronic corticosterone treatment alters c-Fos or FosB immunoreactivity in the rat cerebral cortex
    Réka Szakács
    Department of Psychiatry, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Acta Histochem 112:147-60. 2010

Research Grants

  1. Inhibitory Interneurons in Tourette Syndrome
    Flora M Vaccarino; Fiscal Year: 2010
  2. Schahram Akbarian; Fiscal Year: 2015
  3. Cerebellar Microcircuits: Organization &Development
    Marco Martina; Fiscal Year: 2012
  4. Mriganka Sur; Fiscal Year: 2016
  5. Phenotype analysis of tyrosine hydroxylase neurons in rat and human cortices
    STEPHEN ASMUS; Fiscal Year: 2009
  6. Mechanisms Underlying Activity-Dependent Interneuron Development
    NATALIA VANESA DE MARCO GARCIA; Fiscal Year: 2013
  7. The role of inhibition in the mapping and plasticity of representations in V1
    CAROLINE ANNE RUNYAN; Fiscal Year: 2011
  8. Neuronal Calcium Homeostasis and Synaptic Function
    Istvan Mody; Fiscal Year: 2006
  9. HUMAN MODEL OF VESTIBULAR DEAFFERENTATION
    Akira Ishiyama; Fiscal Year: 2001
  10. Amygdalar and Thalamic Abnormalities in Schizophrenia
    Sabina Berretta; Fiscal Year: 2002

Detail Information

Publications458 found, 100 shown here

  1. ncbi Selective immunocytochemical localisation of calretinin in the human ovary
    S Bertschy
    Institute of Histology and General Embryology, University of Fribourg, Switzerland
    Histochem Cell Biol 109:59-66. 1998
    b>Calretinin is a calcium-binding protein which is primarily expressed by certain cells of the nervous system, both central and peripheral. Its presence in nonexcitable cells has been little studied...
  2. pmc SV40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis
    Thomas Henzi
    Unit of Anatomy, Department of Medicine, University of Fribourg, Route Albert Gockel 1, CH 1700 Fribourg, Switzerland
    Am J Pathol 174:2324-36. 2009
    The calcium-binding protein calretinin has emerged as a useful marker for the identification of mesotheliomas of the epithelioid and mixed types, but its putative role in tumor development has not been addressed previously...
  3. ncbi Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors
    W Glenn McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
    Semin Diagn Pathol 22:3-32. 2005
    ..with sex-cord-like patterns may be greatly aided by the triad of epithelial membrane antigen (EMA), inhibin, and calretinin, the latter two being typically positive and EMA negative in sex cord tumors, the converse being typical of ..
  4. doi Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors
    Chengquan Zhao
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 33:354-66. 2009
    ..stains for markers which have known variable specificity for sex cord-stromal lineage [inhibin, calretinin, MART-1/melan-A, CD99, steroidogenic factor 1 (SF-1, adrenal 4-binding protein), and WT1], were performed in 127 ..
  5. ncbi [A comparative evaluation of immunohistochemical markers for the differential diagnosis between malignant mesothelioma, non-small cell carcinoma involving the pleura, and benign reactive mesothelial cell proliferation]
    Ewa Szczepulska-Wójcik
    Zakład Patomorfologii Instytutu Gruźlicy i Chorób Płuc w Warszawie
    Pneumonol Alergol Pol 75:57-69. 2007
    ..The objective of this study was to evaluate the significance of selected immunohistochemical stains in differentiating MM from non-small cell lung cancers infiltrating the pleura and from benign reactive mesothelial cell proliferation...
  6. ncbi Correlation of morphology, electrophysiology and chemistry of neurons in the myenteric plexus of the guinea-pig distal colon
    A E Lomax
    Department of Anatomy, University of Melbourne, Parkville, Victoria, Australia
    J Auton Nerv Syst 76:45-61. 1999
    ..Dogiel type I neurons were often immunoreactive for nitric oxide synthase or calretinin, as were some small filamentous neurons, while all filamentous ascending interneurons tested were calretinin ..
  7. doi Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:1013-21. 2008
    ..receptor (PR), androgen receptor (AR), CD10, WT1, smooth muscle actin, desmin, AE1/3 cytokeratin, CD34, calretinin, inhibin, c-kit, and Ki-67...
  8. ncbi CD10 and calretinin staining of endocervical glandular lesions, endocervical stroma and endometrioid adenocarcinomas of the uterine corpus: CD10 positivity is characteristic of, but not specific for, mesonephric lesions and is not specific for endometrial
    W G McCluggage
    Department of Pathology, Royal Group of Hospitals Trust, Belfast, UK
    Histopathology 43:144-50. 2003
    ..b>Calretinin has also been shown to be positive in mesonephric lesions...
  9. doi Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates
    Antón Barreiro-Iglesias
    Department of Cell Biology and Ecology, Faculty of Biology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain
    J Comp Neurol 511:438-53. 2008
    ..TH), gamma-aminobutyric acid (GABA), glutamate, calcitonin gene-related peptide (CGRP), neuropeptide Y (NPY), calretinin, and acetylated alpha-tubulin to characterize the neurochemistry and innervation of taste buds in the sea ..
  10. doi Single-dose and chronic corticosterone treatment alters c-Fos or FosB immunoreactivity in the rat cerebral cortex
    Réka Szakács
    Department of Psychiatry, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Acta Histochem 112:147-60. 2010
    ..At the same time we investigated the distribution of interneurons containing calretinin (CR), vasoactive intestinal polypeptide (VIP) and neuropeptide Y (NPY) in chronically treated animals in order ..
  11. ncbi Hippocampal interneurons expressing glutamic acid decarboxylase and calcium-binding proteins decrease with aging in Fischer 344 rats
    A K Shetty
    Department of Surgery Neurosurgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Comp Neurol 394:252-69. 1998
    ..for glutamic acid decarboxylase and those that expressed calcium-binding proteins (parvalbumin, calbindin, and calretinin) in young adult (4-5 months old) and aged (23-25 months old) male Fischer 344 rats...
  12. ncbi Calbindin D28k-immunoreactive afferent nerve endings in the laryngeal mucosa
    Y Yamamoto
    Laboratory of Veterinary Anatomy, Department of Veterinary Science, Faculty of Agriculture, Gifu University, Japan
    Anat Rec 259:237-47. 2000
    ..structures was studied by immunohistochemistry, immunoelectronmicroscopy, and double immunofluorescence with calretinin-immunoreactivity. Moreover, origin of the nerve endings were observed using retrograde tracer, fast blue...
  13. ncbi [Effect of rabies virus infection on the expression of parvalbumin, calbindin and calretinin in mouse cerebral cortex]
    Orlando Torres-Fernández
    Laboratorio de Microscopia, Instituto Nacional de Salud, Bogota, DC, Colombia
    Biomedica 24:63-78. 2004
    ..identified by three neuronal markers: the calcium binding proteins (CaBPs) parvalbumin (PV), calbindin (CB) and calretinin (CR)...
  14. ncbi The immunohistochemical profile of malignant mesotheliomas of the tunica vaginalis: a study of 20 cases
    Alison M Winstanley
    University College Hospital NHS Trust, 3rd floor Rockefeller Bldg, University Street, London WC1E 6JJ, UK
    Am J Surg Pathol 30:1-6. 2006
    ..and selected sections from each case were then examined using an immunohistochemical panel of eight antibodies: calretinin (Zymed, 1:200), epithelial membrane antigen (EMA) (DAKO, 1:50), thrombomodulin (DAKO 1:5), CK7 (DAKO, 1:100), ..
  15. ncbi Calretinin: a novel immunocytochemical marker for mesothelioma
    C Doglioni
    Department of Pathology, City Hospital of Belluno, Italy
    Am J Surg Pathol 20:1037-46. 1996
    ..We now document that two different polyclonal antisera to calretinin consistently immunostain mesothelial cells and malignant mesotheliomas both in routinely fixed and embedded ..
  16. ncbi Development of calretinin immunoreactivity in the mouse inner ear
    C J Dechesne
    Laboratoire de Neurophysiologie Sensorielle, Unité INSERM 254, Montpellier, France
    J Comp Neurol 346:517-29. 1994
    b>Calretinin is a calcium-binding protein of the EF-hand family. It has been previously identified in particular cell types of adult guinea pig, rat, and chinchilla inner ear...
  17. ncbi Connectivity of GABAergic calretinin-immunoreactive neurons in rat primary visual cortex
    Y Gonchar
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Cereb Cortex 9:683-96. 1999
    In rat visual cortex neurons that are immunoreactive for the calcium-binding protein calretinin (CR+) constitute a distinct family which accounts for 17% of gamma-aminobutyric acid (GABA)-expressing cells...
  18. ncbi Primary thymic epithelial tumours of the pleura mimicking malignant mesothelioma
    R L Attanoos
    Department of Histopathology, Llandough Hospital, and Vale NHS Trust, Cardiff, UK
    Histopathology 41:42-9. 2002
    ..To investigate the expression of the mesothelial markers, cytokeratin (CK) 5/6, calretinin and thrombomodulin in a series of mediastinal thymic epithelial tumours.
  19. ncbi A new look at calretinin-immunoreactive amacrine cell types in the monkey retina
    Helga Kolb
    John Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    J Comp Neurol 453:168-84. 2002
    We have examined amacrine cells that are calretinin-immunoreactive (-IR) in the macaque monkey retina with the aim of classifying them into morphological and functional subtypes...
  20. ncbi The role of calretinin, inhibin, melan-A, BCL-2, and C-kit in differentiating adrenal cortical and medullary tumors: an immunohistochemical study
    Paul J Zhang
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19147, USA
    Mod Pathol 16:591-7. 2003
    ..We have recently observed a high level of calretinin expression in normal adrenal cortex but not the medulla and therefore evaluated its diagnostic application for ..
  21. doi Ectopic Leydig cells of testis An immunohistochemical study on tissue microarray
    Sun Young Jun
    Department of Pathology, Hallym University Sacred Heart Hospital, Seoul, Korea
    Ann Diagn Pathol 12:29-32. 2008
    ..Sertoli cells, epididymal cells, mesothelial cells, and epithelial cells in rete testis, immunostainings with calretinin, CD10, inhibin, CK7, and CK20 were performed in 40 cases of orchiectomy specimens using tissue microarray ..
  22. doi Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development
    Hiroyuki Ichikawa
    Department of Oral Function and Anatomy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama, 700 8525, Japan
    Cell Mol Neurobiol 29:691-8. 2009
    ..4% increase as compared to wild type mice). Calretinin (CR)-ir neuron profiles could not be detected in the TG of wild type mice at E12.5-16.5...
  23. ncbi Use of calretinin in the differential diagnosis of unicystic ameloblastomas
    H Coleman
    Division of Oral Pathology, Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa
    Histopathology 38:312-7. 2001
    b>Calretinin, a 29-kDa calcium-binding protein is expressed widely in normal human tissues and tumours including both unicystic and solid and multicystic ameloblastomas...
  24. doi Innervation of tracheal parasympathetic ganglia by esophageal cholinergic neurons: evidence from anatomic and functional studies in guinea pigs
    Stuart B Mazzone
    School of Biomedical Sciences, University of Queensland, St Lucia, QLD 4072, Australia
    Am J Physiol Lung Cell Mol Physiol 298:L404-16. 2010
    ..we describe a subset of nerve fibers, characterized by their immunoreactivity for the calcium-binding protein calretinin, that are densely and selectively associated with cholinergic postganglionic neurons in the guinea pig tracheal ..
  25. ncbi Calretinin-immunoreactive nerves in the uterus, pelvic autonomic ganglia, lumbosacral dorsal root ganglia and lumbosacral spinal cord
    R E Papka
    Department of Neurobiology, Northeastern Ohio Universities, College of Medicine, Rootstown 44272, USA
    Cell Tissue Res 298:63-74. 1999
    Nerves containing the calcium-binding protein calretinin have been reported in several organs but not in female reproductive organs and associated ganglia...
  26. ncbi Chemoarchitecture of the monotreme olfactory bulb
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, Sydney, Australia
    Brain Behav Evol 67:69-84. 2006
    ..reactivity for NADPH diaphorase, and immunoreactivity for calcium binding proteins (parvalbumin, calbindin and calretinin), neuropeptide Y, tyrosine hydroxylase and non-phosphorylated neurofilament protein (SMI-32 antibody) were ..
  27. ncbi Localization of calcium-binding protein (calretinin, 29 kD) in the brain and pituitary gland of teleost fish: an immunohistochemical study
    Arun G Jadhao
    Department of Anatomy and Embryology, Center of Anatomy, School of Medicine, University of Goettingen, Kreuzbergring 36, D 37075 Goettingen, Germany
    Neurosci Res 59:265-76. 2007
    Immunocytochemical techniques were used to investigate the distribution of calretinin in the brain and pituitary gland of the hardhead catfish Arius felis...
  28. ncbi The retina of Spalax ehrenbergi: novel histologic features supportive of a modified photosensory role
    Rafael Cernuda-Cernuda
    Department of Morphology and Cellular Biology, Faculty of Medicine, University of Oviedo, 33071 Oviedo, Spain
    Invest Ophthalmol Vis Sci 43:2374-83. 2002
    ..The retina of the blind mole rat Spalax ehrenbergi was compared with other vertebrate photosensitive organs in an attempt to correlate its histologic organization with a presumptive nonvisual photoreceptor role...
  29. ncbi Organization of human hypothalamus in fetal development
    Yuri Koutcherov
    Prince of Wales Medical Research Institute, Sydney, New South Wales 2031, Australia
    J Comp Neurol 446:301-24. 2002
    ..g.) to newborn, using immunohistochemistry for parvalbumin, calbindin, calretinin, neuropeptide Y, neurophysin, growth-associated protein (GAP)-43, synaptophysin, and the glycoconjugate 3-..
  30. doi Immunocytochemical study of calretinin and calbindin D-28K expression in the retina of three cartilaginous fishes and a cladistian (Polypterus)
    Patricia Graña
    Department of Cell and Molecular Biology, University of A Coruna, A Coruña 15008, Spain
    Brain Res Bull 75:375-8. 2008
    The distribution of two calcium-binding proteins, calbindin D-28K (CB) and calretinin (CR) was studied in the retina of a cladistian, Polypterus senegalus, and three cartilaginous fishes (Scyliorhinus canicula, Raja undulata and Torpedo ..
  31. ncbi Sensory system-predominant distribution of leukotriene A4 hydrolase and its colocalization with calretinin in the mouse nervous system
    Y Chiba
    Department of Pathology, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Aichi 480 0392, Japan
    Neuroscience 141:917-27. 2006
    ..staining demonstrated that most of the leukotriene A4-hydrolase-immunopositive neurons coexpressed calretinin, a calcium-binding protein in neurons...
  32. ncbi Distribution of calcium-binding proteins in the cerebellum
    Enrico Bastianelli
    Proskelia Pharmaceuticals, Romainville, France
    Cerebellum 2:242-62. 2003
    ..They are, almost all, calretinin negative...
  33. ncbi Diagnostic utility of WT1 immunostaining in ovarian sertoli cell tumor
    Chengquan Zhao
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 31:1378-86. 2007
    ..Additionally, inhibin and calretinin immunostaining were performed in all cases of Sertoli cell tumor for purposes of comparing expression with WT1...
  34. ncbi Calretinin in the entorhinal cortex of the rat: distribution, morphology, ultrastructure of neurons, and co-localization with gamma-aminobutyric acid and parvalbumin
    F G Wouterlood
    Department of Anatomy, Graduate School of Neurosciences, Research Institute of Neurosciences, Vrije Universiteit, 1081 BT Amsterdam, The Netherlands
    J Comp Neurol 425:177-92. 2000
    b>Calretinin is a marker that differentially labels neurons in the central nervous system. We used this marker to distinguish subtypes of neurons within the general population of neurons in the entorhinal cortex of the rat...
  35. ncbi The utility of calretinin, inhibin, and WT1 immunohistochemical staining in the differential diagnosis of ovarian tumors
    Helen P Cathro
    Department of Pathology, University of Virginia Health System, PO Box 800214, Charlottesville, VA 22908, USA
    Hum Pathol 36:195-201. 2005
    b>Calretinin has been proposed as a novel marker of ovarian sex cord-stromal tumors (SCST); this study aims to determine whether calretinin can complement or supplant the established utility of inhibin in the differential diagnosis of SCST...
  36. ncbi h-caldesmon, calretinin, estrogen receptor, and Ber-EP4: a useful combination of immunohistochemical markers for differentiating epithelioid peritoneal mesothelioma from serous papillary carcinoma of the ovary
    Camilla E Comin
    Department of Human Pathology and Oncology, University of Florence, Florence, Italy
    Am J Surg Pathol 31:1139-48. 2007
    ..carcinoma of the ovary (25 primary and 15 metastatic to the peritoneum) were immunostained for h-CD, D2-40, calretinin, cytokeratin 5/6, thrombomodulin, estrogen and progesterone receptors (ER and PR), Ber-EP4, B72...
  37. ncbi Distribution of the parvalbumin, calbindin-D28K and calretinin immunoreactivity in globus pallidus of the Brazilian short-tailed opossum (Monodelphis domestica)
    Beata Domaradzka-Pytel
    Department of Anatomy and Neurobiology, Medical University of Gdansk, 1 Debinki St, 80 211 Gdansk, Poland
    Acta Neurobiol Exp (Wars) 67:421-38. 2007
    ..domestica) and distribution of the three calcium binding proteins, parvalbumin (PV), calbindin D-28k (CB) and calretinin (CR) in that nucleus...
  38. pmc Quantitative changes in calretinin immunostaining in the cochlear nuclei after unilateral cochlear removal in young ferrets
    Veronica Fuentes-Santamaria
    Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1010, USA
    J Comp Neurol 483:458-75. 2005
    ..These cells are characterized by neurochemical phenotypes such as levels of calretinin. To test whether or not early deafferentation results in changes in calretinin immunostaining in the cochlear ..
  39. ncbi Calretinin-like immunoreactivity in the Ruffini endings, slowly adapting mechanoreceptors, of the periodontal ligament of the rat incisor
    K Ochi
    Department of Oral Anatomy, Niigata University School of Dentistry, Japan
    Brain Res 769:183-7. 1997
    The distribution and ultrastructural localization of calretinin (CR)-like immunoreactivity (-LI) were investigated in the lingual periodontal ligament of rat incisors...
  40. ncbi [Significance of combining detection of E-cadherin, carcinoembryonic antigen, and calretinin in cytological differential diagnosis of serous effusion]
    Xue Ying Su
    Department of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P R China
    Ai Zheng 23:1185-9. 2004
    ..This study was to evaluate the value of combining detection of E-cadherin,carcinoembryonic antigen (CEA),and calretinin in cytological differential diagnosis of serous effusion.
  41. ncbi Age-dependent alterations of striatal calretinin interneuron density in a genetic animal model of primary paroxysmal dystonia
    Melanie Hamann
    Institute of Pharmacology and Toxicology, School of Veterinary Medicine, Freie Universitat Berlin, Germany
    J Neuropathol Exp Neurol 64:776-81. 2005
    ..Therefore, we determined the density of calretinin-immunoreactive (CR) interneurons in the dt mutant at an age of maximum severity and after spontaneous remission ..
  42. ncbi Characterization of cochlear nucleus principal cells of Meriones unguiculatus and Monodelphis domestica by use of calcium-binding protein immunolabeling
    I Bazwinsky
    Institute of Biology II, University of Leipzig, D 04103 Leipzig, Germany
    J Chem Neuroanat 35:158-74. 2008
    Antibodies directed against calcium-binding proteins (CaBPs) parvalbumin, calbindin-D28k and calretinin were used as neuronal markers to identify and characterize different principal cell types in the mammalian cochlear nucleus...
  43. pmc Calretinin in the peripheral nervous system of the adult zebrafish
    M B Levanti
    Dipartmento di Morfologia, Biochimica, Fisiologia e Produzione Animale, Sezione di Morfologia, Facolta di Medicina Veterinaria, Universita di Messina, Italy
    J Anat 212:67-71. 2008
    b>Calretinin is a calcium-binding protein found widely distributed in the central nervous system and chemosensory cells of the teleosts, but its presence in the peripheral nervous system of fishes is unknown...
  44. pmc Subfield and layer-specific depletion in calbindin-D28K, calretinin and parvalbumin immunoreactivity in the dentate gyrus of amyloid precursor protein/presenilin 1 transgenic mice
    M Popovic
    Departamento de Anatomía Humana y Psicobiología, Facultad de Medicina, Universidad de Murcia, Campus Universitario de Espinardo, Murcia, Spain
    Neuroscience 155:182-91. 2008
    ..The aim of the present study was to investigate the expression of the calcium binding proteins, calbindin-D28K, calretinin and parvalbumin in the dentate gyrus (DG) of amyloid precursor protein (APP)/presenilin 1 (PS1) transgenic (Tg) ..
  45. ncbi Compartmental organization and chemical profile of dopaminergic and GABAergic neurons in the substantia nigra of the rat
    T Gonzalez-Hernandez
    Department of Anatomy Faculty of Medicine, University of La Laguna, La Laguna, Tenerife, Spain
    J Comp Neurol 421:107-35. 2000
    ..double immunostaining for tyrosine hydroxylase (TH), glutamic acid decarboxylase (GAD), cholecystokinin (CCK), calretinin (CR), calbindin (CB), parvalbumin (PV), and nitric oxide synthase (NOS)...
  46. ncbi 'New' functions for 'old' proteins: the role of the calcium-binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with knockout mice
    Beat Schwaller
    Institute of Histology and General Embryology, University of Fribourg, Fribourg, Switzerland
    Cerebellum 1:241-58. 2002
    b>Calretinin (CR), calbindin D-28k (CB) and parvalbumin (PV) belong to the large family of EF-hand calcium-binding proteins, which comprises more than 200 members in man...
  47. ncbi Characterization of gabaergic neurons within the human medial mamillary nucleus
    G Dixon
    Department of Pathology, The University of Sydney, Sydney, NSW 2006, Australia
    Neuroscience 127:365-72. 2004
    ..Results of double-labeling experiments revealed no evidence of calretinin, parvalbumin or calbindin immunoreactivities co-localizing with GAD-IR neurons...
  48. ncbi Analysis of calretinin immunoreactivity in the rat piriform cortex after open field stress during postnatal maturation
    Ewa Badowska-Szalewska
    Department of Anatomy and Neurobiology, Medical University of Gdansk, 80 211 Gdansk, Poland
    Folia Morphol (Warsz) 64:33-40. 2005
    In our study we used c-Fos protein to identify whether cells containing calretinin (CR) in the rat piriform cortex are engaged in the response to stress stimulation and to find out how this expression changes during maturation (PC)...
  49. ncbi The anterior olfactory nucleus and piriform cortex of the echidna and platypus
    Ken W S Ashwell
    Department of Anatomy, School of Medical Sciences, The University of New South Wales, New South Wales, Sydney, Australia
    Brain Behav Evol 67:203-27. 2006
    ..and acetylcholinesterase, and immunoreactivity for calcium-binding proteins (parvalbumin, calbindin and calretinin) and tyrosine hydroxylase. Golgi impregnations were also available for the echidna...
  50. doi Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor alpha1
    Karin Wallis
    Department of Cell and Molecular Biology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    J Neurosci 28:1904-15. 2008
    ..with severely delayed appearance of parvalbumin-immunoreactive GABAergic interneurons and increased numbers of calretinin-immunoreactive cells in the neocortex...
  51. pmc Dopaminergic innervation of interneurons in the rat basolateral amygdala
    C R Pinard
    Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, 6439 Garner s Ferry Rd, VA Building 1, D 46, Columbia, SC 29208, USA
    Neuroscience 157:850-63. 2008
    ..interneuronal populations in the rat basolateral nucleus labeled using antibodies to parvalbumin (PV) or calretinin (CR). The basolateral nucleus exhibited a dense innervation by TH+ axons...
  52. doi The diagnostic utility of immunohistochemistry in distinguishing primary skin adnexal carcinomas from metastatic adenocarcinoma to skin: an immunohistochemical reappraisal using cytokeratin 15, nestin, p63, D2-40, and calretinin
    Meera Mahalingam
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02114, USA
    Mod Pathol 23:713-9. 2010
    ..We performed CK15 and nestin, as well as previously reported stains (such as p63, D2-40, and calretinin) on 113 cases (59 primary adnexal carcinomas and 54 cutaneous metastases)...
  53. pmc Influence of a subtype of inhibitory interneuron on stimulus-specific responses in visual cortex
    Rong Mao
    Picower Institute for Learning and Memory, Cambridge, MA 02139, USA
    Cereb Cortex 22:493-508. 2012
    ..Dlx1(-/-) mice, which have a selective reduction in cortical dendrite-targeting interneurons (DTIs) that express calretinin, neuropeptide Y, and somatostatin...
  54. ncbi Morphological and quantitative analysis of cerebellar cortical cells in Alzheimer's disease
    Tomasz Stepien
    Department of Neuropathology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Folia Neuropathol 50:250-60. 2012
    ..The aim of our study was to analyze the expression of calcium-binding proteins (calbindin, calretinin, parvalbumin) in cortical neurons of the cerebellum in patients diagnosed with Alzheimer's disease (experimental ..
  55. doi Adenomatoid tumor of the small intestine: the first case report and review of the literature
    I Weng Lao
    Fudan University Shanghai Cancer Center, Shanghai, China
    Int J Surg Pathol 22:727-30. 2014
    ..nature of the lesion was subsequently verified by the immunopositivity for pancytokeratin (AE1/AE3), HBME-1, calretinin, D2-40, and WT1 with cells lining the tubules and glandular spaces...
  56. doi Inhibin-α, E-cadherin, calretinin and Ki-67 antigen in the immunohistochemical evaluation of canine and human testicular neoplasms
    Rafal Ciaputa
    Department of Pathomorphology and Forensic Veterinary Science, Chair of Pathology, Faculty of Veterinary Medicine, University of Environmental and Life Sciences, Wroclaw, Poland
    Folia Histochem Cytobiol 52:326-34. 2014
    ....
  57. doi Physical training decreases susceptibility to pilocarpine-induced seizures in the injured rat brain
    Zuzanna Setkowicz
    Department of Neuroanatomy, Institute of Zoology, Jagiellonian University, 9 Gronostajowa St, 30 387 Krakow, Poland
    Brain Res 1642:20-32. 2016
    ..effects of the brain injury and of physical training detected significant quantitative changes in parvalbumin-, calretinin- and NPY-immunopositive neuronal populations...
  58. pmc The Effects of Realistic Synaptic Distribution and 3D Geometry on Signal Integration and Extracellular Field Generation of Hippocampal Pyramidal Cells and Inhibitory Neurons
    Attila I Gulyás
    Laboratory of Cerebral Cortex Research, Institute of Experimental Medicine, Hungarian Academy of Sciences Budapest, Hungary
    Front Neural Circuits 10:88. 2016
    ..b>Calretinin-containing interneurons were found to be electrotonically extended, which suggests the possibility of complex ..
  59. ncbi Calcium binding by chick calretinin and rat calbindin D28k synthesised in bacteria
    W T Cheung
    Physiological Laboratory, University of Cambridge, England
    Eur J Biochem 215:401-10. 1993
    b>Calretinin is a member of the EF-hand calcium-binding protein family, with a high similarity with calbindin D28k...
  60. ncbi Local-circuit neurones in the medial prefrontal cortex (areas 25, 32 and 24b) in the rat: morphology and quantitative distribution
    P L Gabbott
    University Department of Pharmacology, Oxford, England
    J Comp Neurol 377:465-99. 1997
    ..Cortical interneurones were identified immunocytochemically by their expression of calretinin (CR), parvalbumin (PV), and calbindin D-28k (CB) immunoreactivity...
  61. ncbi Characterization of CHS4 (CAL2), a gene of Saccharomyces cerevisiae involved in chitin biosynthesis and allelic to SKT5 and CSD4
    J A Trilla
    Instituto de Microbiologia Bioquimica, Consejo Superior de Investigaciones Científicas Universidad de Salamance and Departamento de Microbiología y Genética, Spain
    Yeast 13:795-807. 1997
    We have cloned CHS4, a gene that complements the resistance to Calcofluor of the Saccharomyces cerevisiae cal2 mutant. We show that CHS4 is allelic to the previously described SKT5 and CSD4 genes...
  62. ncbi Postnatal development of calretinin- and parvalbumin-positive interneurons in the rat neostriatum: an immunohistochemical study
    B Schlosser
    Institute of Physiology, University of Munich, Germany
    J Comp Neurol 405:185-98. 1999
    ..proteins have been identified in the striatum of adult animals: neurons expressing either parvalbumin (PV) or calretinin (CR)...
  63. ncbi Cholecystokinin activates specific enteric neurons in the rat small intestine
    Ayman I Sayegh
    Gastroenterology Laboratory, Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, Tuskegee University, 36088, Tuskegee, AL, USA
    Peptides 24:237-44. 2003
    ..markers that we examined were: nitric oxide synthase (NOS), neurokinin-1 receptor (NK-1R), calbindin (Cal), Calretinin (Calr), and neurofilament-M (NF-M)...
  64. ncbi Expression of Notch1 and Jagged2 in the enteric nervous system
    Guy R Sander
    Child Health Research Institute, Womens and Childrens Hospital, 72 King William Road, North Adelaide, South Australia 5006, Australia
    J Histochem Cytochem 51:969-72. 2003
    ..Notch1 was preferentially expressed in cholinergic neurons lacking calretinin or nitric oxide synthase (NOS), whereas Jagged2 was present in most neuron subtypes...
  65. ncbi The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma
    Nelson G Ordonez
    University of Texas, Texas 77030, USA
    Am J Surg Pathol 27:1031-51. 2003
    ..epithelioid mesotheliomas and 50 lung adenocarcinomas were investigated for expression of the following markers: calretinin, cytokeratin 5/6, WT1, thrombomodulin, mesothelin, CD44S, HBME-1, N-cadherin, E-cadherin, MOC-31, thyroid ..
  66. ncbi Neural progenitor cells do not differentiate prematurely in presenilin-1 null mutant mice
    Paul H Wen
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Neurosci Lett 371:249-54. 2004
    ..with seven neuronal specific markers (MAP2, beta-III tubulin, GABA, reelin, GluR2/3, calbindin, and calretinin) failed to reveal any evidence of premature neuronal differentiation in PS1-/- telencephalon...
  67. ncbi [Tenosynovial giant cell tumor]
    C Kuhnen
    Institut fur Pathologie, Register für Gliedmassentumoren, Berufsgenossenschaftliche Kliniken Bergmannsheil, Ruhr Universitat Bochum
    Pathologe 26:96-110. 2005
    ..Immunohistochemically, the diffuse-type exhibited focal expression of CD31 (in 75% of tumors) and calretinin (in 63%) besides CD68-staining.
  68. ncbi The calcium binding proteins calbindin, parvalbumin, and calretinin have specific patterns of expression in the gray matter of cat spinal cord
    Roberta Anelli
    Department of Physiology, Northwestern Feinberg School of Medicine, Chicago, Illinois, USA
    J Neurocytol 34:369-85. 2005
    ..the localization and morphology of neurons expressing the CBPs calbindin-28 KD (CB), parvalbumin (PV), and calretinin (CR), and co-expressing CB and PV, CB and CR, and PV and CR...
  69. ncbi Postnatal subventricular zone progenitors give rise not only to granular and periglomerular interneurons but also to interneurons in the external plexiform layer of the rat olfactory bulb
    Zhengang Yang
    Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, People s Republic of China 200032
    J Comp Neurol 506:347-58. 2008
    ..A subset of these cells was made up of calcium-binding protein calretinin (CR)(+) interneurons...
  70. ncbi Primary malignant mesothelioma developed in liver
    Dong Sik Kim
    Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Hepatogastroenterology 55:1081-4. 2008
    ..Immunohistochemically, the tumor cells were strongly positive for calretinin and cytokeratin 5 and negative for hepatocyte markers...
  71. doi Increased neurogenesis after hypoxic-ischemic encephalopathy in humans is age related
    Wulf Rainer C Mattiesen
    Department of Neurology, Georg August University, Gottingen, Germany
    Acta Neuropathol 117:525-34. 2009
    ..immature granule cells during axon guidance and outgrowth (assessed by TUC-4 immunohistochemistry) and of young calretinin-expressing postmitotic neurons were increased in the granule cell layer of cases who had suffered from HIE (P = ..
  72. pmc Activity-dependent codevelopment of the corticospinal system and target interneurons in the cervical spinal cord
    Samit Chakrabarty
    Department of Neuroscience, Columbia University, New York, New York 10032, USA
    J Neurosci 29:8816-27. 2009
    ..We used immunohistochemistry of choline acetyltransferase (ChAT), calbindin, calretinin, and parvalbumin to mark interneurons...
  73. ncbi Pure Sertoli cell tumor. a case report and review of the literature
    A Zizi-Sermpetzoglou
    Pathology Department of Tzaneion General Hospital of Pireaus, Greece
    Eur J Gynaecol Oncol 31:117-9. 2010
    ..The immunohistochemical panel which usually includes EMA, inhibin, chromogranine, CD99 and calretinin is often helpful in establishing the diagnosis...
  74. doi Malignant pleural mesothelioma in a female lion (Panthera leo)
    E Bollo
    Dipartimento di Patologia Animale, Universita degli Studi di Torino, Via L da Vinci 44, 10095 Grugliasco TO, Italy
    Res Vet Sci 91:116-8. 2011
    ..Immunohistochemistry revealed immunoreactivity for pancytokeratin and vimentin. None of the cells expressed calretinin antigen...
  75. doi Exclusion of all three calbindins from a calcium-ferry role in rat enamel cells
    Michael J Hubbard
    Department of Biochemistry, University of Otago, Dunedin, New Zealand
    Eur J Oral Sci 119:112-9. 2011
    ..and proteomic approaches to obtain definitive identification and quantification of the 30-kDa calbindin (calretinin) and calbindin-9 kDa (S100-G) in enamel epithelium from rat...
  76. doi Age-related changes in calbindin and calretinin immunoreactivity in the central auditory system of the rat
    Ladislav Ouda
    Department of Auditory Neuroscience, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Exp Gerontol 47:497-506. 2012
    ..with immunohistochemistry and the western blot technique the effect that aging has on the calbindin- and calretinin-expressing system of neurons in the higher structures of the central auditory pathway, in the inferior ..
  77. pmc Chronic levodopa administration followed by a washout period increased number and induced phenotypic changes in striatal dopaminergic cells in MPTP-monkeys
    Carla Dicaudo
    Laboratory of Regenerative Therapy and Department of Neurology, Division of Neuroscience, University of Navarra, Pamplona, Spain
    PLoS ONE 7:e50842. 2012
    ..of the striatal TH-ir cells using antibodies against: TH, anti-glutamate decarboxylase (GAD(67)) anti-calretinin (CR) anti-dopa decarboxylase (DDC) and anti-dopamine and cyclic AMP-regulated phosphoprotein (DARPP-32)...
  78. pmc Malignancy knows no boundaries
    Sandeep Batra
    Department of Medical Oncology, Medanta, The Medicity, Gurgaon, Haryana, India
    BMJ Case Rep 2013:. 2013
    ..The tumour cells were pancytokeratin, CA125, WT1 positive and CDX2, CD10, villin, calretinin negative; thus immunohistochemically suggesting a primary tumor arising from ovary...
  79. doi α7 nicotinic receptor agonist reactivates neurogenesis in adult brain
    Sridhar Narla
    Department of Pathology and Anatomical Sciences, State University of New York at Buffalo, Buffalo, NY, USA
    Biochem Pharmacol 86:1099-104. 2013
    ..is observed in different brain regions, including: (1) βIII Tubulin-expressing cortical neurons, (2) calretinin expressing hippocampal neurons and (3) cells in substantia nigra (SN) expressing predopaminergic Nurr1+phenotype...
  80. doi The clinical significance of pathological studies of congenital intestinal atresia
    Xiuliang Wang
    Department of General Surgery, Children s Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, P R China Key Laboratory of Pediatrics in Chongqing, CSTC2009CA5002, Chongqing, P R China Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing 400014, P R China
    J Pediatr Surg 48:2084-91. 2013
    ..disorders in intestinal atresia patients by investigating the expression profiles of proteins, including calretinin (CR), glial-derived neurotrophic factor (GDNF), bone morphogenetic protein 2 (BMP-2), c-kit, α-smooth muscle ..
  81. doi Dendritic inhibition provided by interneuron-specific cells controls the firing rate and timing of the hippocampal feedback inhibitory circuitry
    Leonid Tyan
    Axis of Cellular and Molecular Neuroscience, Institut universitaire en santé mentale de Québec, Department of Biochemistry, Microbiology and Bio informatics, Universite Laval, Quebec G1J 2G3, Canada, and Department of Bioengineering, Stanford University, Stanford, California 94305 5444
    J Neurosci 34:4534-47. 2014
    ..We found that type 3 IS (IS3) cells that coexpress the vasoactive intestinal polypeptide (VIP) and calretinin contact several distinct types of interneurons within the hippocampal CA1 stratum oriens/alveus (O/A), with ..
  82. pmc Adult type granulosa cell tumor of the testis with a heterologous sarcomatous component: case report and review of the literature
    Thomas E O Schubert
    Institute of Pathology, Medical University Innsbruck, Muellerstrasse 44, A 6020 Innsbruck, Austria
    Diagn Pathol 9:107. 2014
    ..CD 99 and the progesterone receptor were positive in both tumor components, inhibin and calretinin only in the granulosa cells, and pancytokeratin only in the sarcomatouse one...
  83. pmc Trajectory of the main GABAergic interneuron populations from early development to old age in the rat primary auditory cortex
    Lydia Ouellet
    Department of Neurology and Neurosurgery, Montreal Neurological Institute Montreal, QC, Canada
    Front Neuroanat 8:40. 2014
    ..methods, using antibodies against gamma aminobutyric acid (GABA), parvalbumin (PV), somatostatin (SOM), calretinin (CR), vasoactive intestinal peptide (VIP), choline acetyltransferase (ChAT), neuropeptide Y (NPY), and ..
  84. pmc Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract
    Hercules T Maguma
    Department of Pharmacology and Toxicology, VCU Program in Enteric Neuromuscular Sciences, Virginia Commonwealth University, Richmond, Virginia, United States of America
    PLoS ONE 9:e103894. 2014
    ..arrestin2 co-localized with choline acetyltransferase and calretinin. In contrast, β-arrestin2 neither co-localized with substance P, nitric oxide synthase nor calbindin...
  85. pmc Calcium-binding proteins in focal cortical dysplasia
    Giorgi Kuchukhidze
    Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria
    Epilepsia 56:1207-16. 2015
    ..We compared numbers of neurons containing calcium-binding proteins parvalbumin (PV), calbindin (CB), and calretinin (CR) and densities of respective fibers in lateral temporal lobe surgical specimens of 17 patients with FCD with ..
  86. pmc Selective reduction of cerebral cortex GABA neurons in a late gestation model of fetal alcohol spectrum disorder
    John F Smiley
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA Department of Psychiatry, New York University Medical Center, New York, NY, USA Electronic address
    Alcohol 49:571-80. 2015
    ..However, counts of calretinin (CR) and parvalbumin (PV) subtypes of GABAergic neurons showed a striking >30% reduction of neuron number...
  87. pmc Visuo-vestibular information processing by unipolar brush cells in the rabbit flocculus
    Robert A Hensbroek
    Department of Neuroscience and Physiology, New York University Medical School, New York, NY, 10016, USA
    Cerebellum 14:578-83. 2015
    ..5 s. We suggest that the UBCs recorded in this study mostly belong to the type I UBC category (calretinin-positive) and that they can play diverse roles in floccular visuo-vestibular information processing, such as ..
  88. doi Organization of the nitrergic neuronal system in the primitive bony fishes Polypterus senegalus and Erpetoichthys calabaricus (Actinopterygii: Cladistia)
    Jesus M Lopez
    Department of Cell Biology, Faculty of Biology, University Complutense, 28040, Madrid, Spain
    J Comp Neurol 524:1770-804. 2016
    ..was conducted for simultaneous detection of NOS with tyrosine hydroxylase, choline acetyltransferase, calbindin, calretinin, and serotonin, to establish accurately the localization of the nitrergic neurons and fibers and to assess ..
  89. pmc Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments
    Guillermo Coronas-Samano
    The John B Pierce Laboratory New Haven, CT, USA
    Front Aging Neurosci 8:268. 2016
    ..These neurobehavioral deficits of the Fus1 KO mice at this relatively young age are highly relevant to sAD, making them suitable for effective research on pharmacological targets in the context of early intervention of sAD...
  90. pmc The enteric nervous system and the musculature of the colon are altered in patients with spina bifida and spinal cord injury
    Marjanne den Braber-Ymker
    Department of Pathology, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
    Virchows Arch . 2017
    ..periodic acid Schiff, and elastic von Gieson staining, and immunohistochemistry with antibodies against HuC/D, calretinin, S100, CD117, α-smooth muscle actin, and desmin...
  91. ncbi Vasoactive intestinal polypeptide containing neurones in monkey medial prefrontal cortex (mPFC): colocalisation with calretinin
    P L Gabbott
    University Department of Pharmacology, Oxford, UK
    Brain Res 744:179-84. 1997
    ..The majority (78.0%) of VIP+ neurones were bipolar cells located mainly in layers 2/3. Calretinin (CR) immunoreactivity was colocalised in 80.5% of VIP+ neurones...
  92. ncbi Two distinct subgroups of cholecystokinin-immunoreactive cortical interneurons
    Y Kubota
    Laboratory for Neural Circuits, Institute of Physical and Chemical Research RIKEN, Moriyama ku, Nagoya Aichi, Japan
    Brain Res 752:175-83. 1997
    ..or bitufted although some were multipolar and demonstrated vasoactive intestinal polypeptide and in a few case calretinin immunoreactivity...
  93. ncbi Dendrite development and target innervation of displaced retinal ganglion cells of the chick (Gallus gallus)
    J Mey
    Institut fur Biologie II, RWTH Aachen, Kopernikusstrasse 16, 52074, Aachen, Germany
    Int J Dev Neurosci 19:517-31. 2001
    ..The histological development of the nBOR proceeded such that calretinin-immunoreactive neurons were observed from E10 onwards and morphologically described cell types evolved after E12.
  94. ncbi Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus
    Angela A Coutts
    Department of Biomedical Sciences, University of Aberdeen, Aberdeen, Scotland AB25 2ZD, United Kingdom
    J Comp Neurol 448:410-22. 2002
    ..with antibodies against the CB(1) receptor and choline acetyltransferase, neurofilament proteins, calbindin, calretinin, synapsin I, microtubule-associated protein-2, calcitonin gene-related peptide, or substance P...
  95. ncbi Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons
    Wolfgang Hartig
    Paul Flechsig Institute for Brain Research, University of Leipzig, D 04109 Leipzig, Germany
    J Comp Neurol 465:1-10. 2003
    ..VGLUT2 was shown to be coexpressed with calretinin in the dense axonal plexus known to emanate from the paraventricular thalamic nucleus...
  96. ncbi Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse
    Nobuaki Tamamaki
    Department of Morphological Brain Science, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
    J Comp Neurol 467:60-79. 2003
    ..Moreover, we used the knock-in mice to investigate the colocalization of GFP with NeuN, calretinin (CR), parvalbumin (PV), and somatostatin (SS) in the frontal motor cortex...
  97. ncbi Hypothalamus of the human fetus
    Yuri Koutcherov
    Prince of Wales Medical Research Institute, The University of New South Wales, Barker Street, NSW 2031, Randwick, Australia
    J Chem Neuroanat 26:253-70. 2003
    ..g.) to newborn, using immunohistochemistry for parvalbumin, calbindin, calretinin, neuropeptideY, neurophysin, growth associated protein GAP43, synaptophysin and glycoconjugate, 3-fucosyl-N-..
  98. ncbi Postnatal development of calcium-binding proteins immunoreactivity (parvalbumin, calbindin, calretinin) in the human entorhinal cortex
    L Grateron
    Department of Health Sciences, School of Medicine and CRIB, University of Castilla La Mancha, Avenida de Almansa 02006, Albacete, Spain
    J Chem Neuroanat 26:311-6. 2003
    ..The presence of interneurons expressing calcium-binding proteins (parvalbumin, calbindin-D28K (calbindin) and calretinin) is well documented in the adult human entorhinal cortex...
  99. ncbi Ber-EP4 and anti-calretinin antibodies: a useful combination for differential diagnosis of various histological types of ovarian cancer cells and mesothelial cells
    Satoshi Okamoto
    Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
    Tohoku J Exp Med 206:31-40. 2005
    ..In the tissue specimens, Ber-EP4, a monoclonal antibody of epithelial antigen, and a polyclonal antibody against calretinin, which is expressed in mesothelium, are used in differentiating reactive mesothelial cells from ovarian ..
  100. ncbi Expression of A-type K channel alpha subunits Kv 4.2 and Kv 4.3 in rat spinal lamina II excitatory interneurons and colocalization with pain-modulating molecules
    Hsin Yi Huang
    Institute of Neuroscience, National Yang Ming University, Brain Research Centre, University System of Taiwan, Taipei, Taiwan 112, Republic of China
    Eur J Neurosci 22:1149-57. 2005
    ..Kv 4.3(+) neurons were a subset of excitatory inerneurons with calretinin(+)/calbindin(-)/PKCgamma(-) markers, and a fraction of them expressed micro-opioid receptors. Kv 4...
  101. doi Immunohistochemical analysis of neuron types in the mouse small intestine
    Zheng Dong Qu
    Department of Anatomy and Cell Biology and Centre for Neuroscience, University of Melbourne, Parkville, Victoria, 3010, Australia
    Cell Tissue Res 334:147-61. 2008
    ..b>Calretinin immunoreactivity was found in a high proportion of neurons (52%). Many of these had TK immunoreactivity...

Research Grants60

  1. Inhibitory Interneurons in Tourette Syndrome
    Flora M Vaccarino; Fiscal Year: 2010
    ..In the first specific aim we will ascertain whether the number and relative proportion of PV, calretinin (CR), calbindin (CB) and cholinergic (Ach) neurons is altered in striatum and globus pallidus of TS brains as ..
  2. Schahram Akbarian; Fiscal Year: 2015
    ..defined by differential expression of calcium buffering proteins Parvalbumin (PARV) or Calbindin (CALB) or Calretinin (CALR)...
  3. Cerebellar Microcircuits: Organization &Development
    Marco Martina; Fiscal Year: 2012
    ..is chemically heterogeneous and consists of two main chemotypes, a subset expressing the calcium binding protein calretinin, and a calretinin-negative subset expressing the metabotropic glutamate receptor mGluR1a...
  4. Mriganka Sur; Fiscal Year: 2016
    ..subpopulations in mouse V1 marked by a genetic cre-lox system, and examine the hypothesis that parvalbumin- and calretinin-expressing interneurons have distinct response properties...
  5. Phenotype analysis of tyrosine hydroxylase neurons in rat and human cortices
    STEPHEN ASMUS; Fiscal Year: 2009
    ..A subset of these cells colocalizes with the GABA synthetic enzyme GAD and with calretinin, present in one of three distinct interneuron subpopulations...
  6. Mechanisms Underlying Activity-Dependent Interneuron Development
    NATALIA VANESA DE MARCO GARCIA; Fiscal Year: 2013
    ..Indeed, my previous work indicates that the radial migration and morphological development of calretinin and reelin but not vasoactive intestinal peptide interneurons, the major subtypes derived from the caudal ..
  7. The role of inhibition in the mapping and plasticity of representations in V1
    CAROLINE ANNE RUNYAN; Fiscal Year: 2011
    ..label three subtypes of inhibitory cells, soma-targeting parvalbumin-positive (PV+), dendrite-targeting calretinin-positive (CR+), and dendrite-targeting somatostatin- positive cells (SOM+)...
  8. Neuronal Calcium Homeostasis and Synaptic Function
    Istvan Mody; Fiscal Year: 2006
    ..resolve the Ca2+-binding kinetics of three neuronal CBPs including calbindin-D28K (CB28K) Parvalbumin (PV), and calretinin (CR) at or near physiological conditions; 2) to determine the physiological Ca2+-binding kinetics of substrate-..
  9. HUMAN MODEL OF VESTIBULAR DEAFFERENTATION
    Akira Ishiyama; Fiscal Year: 2001
    ..3) Does retrograde degeneration occur in the presence of intact afferent dendrites? 4) Is there a subtype of calretinin immunoreactive Scarpa~s ganglion neuron which is resistant to retrograde degeneration? 5) Is there a qualitative ..
  10. Amygdalar and Thalamic Abnormalities in Schizophrenia
    Sabina Berretta; Fiscal Year: 2002
    ..Using irnmunocytochemical (ICC) localization of glutamate, glutamate amino decarboxylase (GAD), parvalbumin, calretinin, calbindin-D28k, somatostatin, cholecystokinin, corticotropin releasing factor, neuropeptide Y, and vasoactive ..
  11. OLFACTORY NEURODEVELOPMENTAL PATHOLOGY IN SCHIZOPHRENIA
    STEVEN ARNOLD; Fiscal Year: 2002
    ..composition of the glomerulus will be quantified after immunolabeling for synaptophysin, tyrosine hydroxylase, calretinin, calbindin D28k, NCAMs and GAP- 43...
  12. Methylphenidate & gene expression in the rat brain.
    JOAN BAIZER; Fiscal Year: 2004
    ..abstract_text> ..
  13. CELL INTERACTIONS IN THE DEVELOPING AUDITORY SYSTEM
    Thomas Parks; Fiscal Year: 2003
    ..neurons employ several calcium- regulating mechanisms, including high levels of the calcium- binding protein calretinin. The characteristic features of AMPA receptors in auditory neurons develop after the onset of spontaneous ..
  14. SYNAPTIC ORGANIZATION OF THE BASOLATERAL AMYGDALA
    ALEXANDER MCDONALD; Fiscal Year: 2008
    ..abstract_text> ..
  15. SYNAPTIC REGENERATION IN LESIONED, GRAFTED HIPPOCAMPUS
    Ashok Shetty; Fiscal Year: 1999
    ..This reviewer would have liked to have seen one of the quantitative analyses for parvalbumin, calbindin, calretinin or GAD actually carried through to fruition...
  16. CHARACTERIZATION OF INTRINSIC VISUAL CORTICAL NEURONS
    Andreas Burkhalter; Fiscal Year: 2007
    ..we propose to use transgenic mice, which express Green Fluorescent Protein (GFP) either in parvalbumin (PV)- or calretinin/somatostatin-immunoreactive (i.e...
  17. Muller glia and neuronal regeneration in the retina
    Andy Fischer; Fiscal Year: 2009
    ..This information could be applied to not only stimulate neural regeneration to treat sight-threatening diseases of the retina, but also to control gliosis that may be detrimental to the pathogenesis of retinal disorders. ..
  18. Auditory cortex asymmetry in normals and schizophrenics
    John Smiley; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  19. Non-Homeostatic Neural Controls of Food Intake
    Hans Rudolf Berthoud; Fiscal Year: 2010
    ..abstract_text> ..
  20. Multiscale Analysis of Neuronal Morphology
    Patrick Hof; Fiscal Year: 2009
    ..Such studies will provide crucial insight into general mechanisms of memory induction and maintenance that underlie normal cognitive function, its dysfunction in diseased states, and potential mechanisms for its restoration. ..
  21. QUANTITATIVE MORPHOPHYSIOLOGY OF VESTIBULAR AFFERENTS
    GOLDA KEVETTER; Fiscal Year: 2004
    ..g., calretinin. These experiments will extend this data, documenting significant correlations between the afferent's distal ..
  22. HIPPOCAMPAL NETWORK STRUCTURE AND FUNCTION IN EPILEPSY
    ROBERT SLOVITER; Fiscal Year: 2006
    ..abstract_text> ..
  23. Repair of Chronially Injured Hippocampus by Grafts
    Ashok Shetty; Fiscal Year: 2006
    ..These studies also have implications for the treatment of other neurodegenerative conditions such as stroke and head injury. [unreadable] [unreadable]..
  24. Behavior of Stem Cells in the Lesioned Aging Hippocampus
    Ashok Shetty; Fiscal Year: 2006
    ..abstract_text> ..
  25. FUNCTIONAL ORGANIZATION OF THE VAGAL-ENTERIC INTERFACE
    Hans Rudolf Berthoud; Fiscal Year: 2003
    ..abstract_text> ..
  26. SYNAPTIC ORGANIZATION OF THE BASOLATERAL AMYGDALA
    ALEXANDER MCDONALD; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  27. DEVELOPMENT OF THE GUSTATORY SYSTEM
    RICHARD NORTHCUTT; Fiscal Year: 2005
    ..To test the hypothesis that retinoic acid acts as a signal to pattern endoderm directly during gastrulation (aim 3), presumptive pharyngeal endoderm will be excised, exposed to retinoic acid, and cultured. ..
  28. Novel Brain Neuroimaging Markers of Age-Related Mobility Impairment
    Caterina Rosano; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  29. Estrogenic Effect on Hippocampal Theta Rhythm and Memory
    Csaba Leranth; Fiscal Year: 2004
    ....
  30. Calcium Homeostasis and Neonatal Brain Injury
    Christopher Turner; Fiscal Year: 2009
    ....
  31. Regulation of Laminar Fate in Cerebral Cortex
    Robert Hevner; Fiscal Year: 2006
    ..If molecular fates are aEered in heterochronic or Rein mutant cortex, this would suggest that certain aspects of laminar fate can be regulated post-mitotically. ..
  32. Cell Type-Specific Gene Delivery in Mammalian Retina
    Vijay Sarthy; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  33. Negative Effects of Bisphenol A on the Monkey CNS
    Csaba Leranth; Fiscal Year: 2008
    ..Therefore, we propose to reveal the effect of BPA on estrogen-induced spine synapse formation in the brain of non-human primates, which will provide more relevance to human health. [unreadable] [unreadable] [unreadable]..
  34. Muller Cell Role in Retinal Diseases
    Vijay P Sarthy; Fiscal Year: 2010
    ..abstract_text> ..
  35. Antiepileptogenic & Disease Modifying Effects of AEDs
    Asla Pitkanen; Fiscal Year: 2005
    ..abstract_text> ..
  36. K-OPIOID SYSTEMS--SEX AND PREGNANCY LINKED DIFFERENCES
    CARRIE DRAKE; Fiscal Year: 2002
    ..The results of these studies will be relevant to understanding gender differences in analgesia, and may aid in the development of analgesic drugs and their targeting to appropriate patient populations. ..
  37. DOPAMINE AND RETINAL ADAPTATION
    Paul Witkovsky; Fiscal Year: 2001
    ....
  38. NEUROTRANSMITTER TRANSPORTERS IN THE RETINA
    Vijay Sarthy; Fiscal Year: 2003
    ....
  39. Altered Inhibitory Prefrontal Circuitry in Schizophrenia
    DAVID VOLK; Fiscal Year: 2003
    ..After a 3 month survival period, we will quantify any changes in the mRNA expression of PFC GABA markers using in situ hybridization and grain counting techniques. ..
  40. Molecular mechanisms of vestibular hair cell exocytosis
    FELIX SCHWEIZER; Fiscal Year: 2009
    ..A detailed understanding of the proteins and mechanisms of release at this initial sensory synapse aid in identifying novel therapeutic approaches targeting vestibular dysfunction. ..
  41. delta-Catenin and Cell-Cell Adhesion in Prostate Cancer
    Qun Lu; Fiscal Year: 2010
    ..Understanding the posttranslational modifications that control 8-catenin functions will unravel mechanisms by which S-catenin modulates gene expression and promotes CaP in vivo. ..
  42. PLASTICITY AND DESCENDING CONTROL OF SENSORY PROCESSING
    CURTIS BELL; Fiscal Year: 2004
    ..The results are expected to be a source of hypotheses into the central processing of sensory information in general as well as into the processing of information in other cerebellum-like structures. ..
  43. CELL AND MOLECULAR BIOLOGY OF RETINAL MULLER CELLS
    Vijay Sarthy; Fiscal Year: 2001
    ..The importance of studying Muller cells is emphasized by their involvement in many human retinal diseases leading to blindness. ..
  44. Global vs. Focal Neuroimaging Markers of Dementia Risk
    Caterina Rosano; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  45. Differential Gene Expression in the Cochlear Nucleus
    David Friedland; Fiscal Year: 2008
    ..These data will also provide a powerful template upon which to test and design novel treatments for improving hearing, discrimination and tinnitus in a significant portion of the population. ..
  46. Genomic Characterization in Depression and Suicide.
    Etienne Sibille; Fiscal Year: 2007
    ..The training program proposes formal courses, supervised training and frequent interactions with several research groups involved in pioneering aspects of genomic research in mood disorders. [unreadable] [unreadable]..
  47. GENETIC MODEL FOR THE ROLE OF NEUROGENESIS IN ANTIDEPRESSANT RESPONSE
    ROBERT BEECH; Fiscal Year: 2007
    ..This, in turn, should allow for a more rational search for new medications for the treatment of depression, and potentially other mental illnesses as well. [unreadable] [unreadable] [unreadable]..
  48. AN ADAPTIVE SENSORY PROCESSOR
    CURTIS BELL; Fiscal Year: 2006
    ..The results may also be a source of insight into other cerebellum-like structures, such as the dorsal cochlear nucleus of mammals or the cerebellum itself. ..
  49. Delta-Catenin Cleavage by Presenilin and Synaptic Remodeling
    Qun Lu; Fiscal Year: 2006
    ..It will also lay the foundation for future R01 investigation of the roles of delta-catenin proteolytic fragments in AD pathogenesis. ..
  50. Brain, Behavior and Biological Rhythms
    LAWRENCE MORIN; Fiscal Year: 2006
    ..The overall goal of the project is to further elucidate the contribution of the visual system to the regulation of circadian rhythm response to light with particular emphasis on phase control. ..
  51. Female Reproductive Organs and Their Innervation.
    RAYMOND PAPKA; Fiscal Year: 2006
    ..Finally, knowledge of estrogen responsive sensory neurons has important implications for understanding neuropathic pain syndromes influenced by estrogen levels. ..
  52. Opioid Regulation of cAMP in the Vestibular Epithelia
    Paul Popper; Fiscal Year: 2006
    ..In addition, characterization distributions of the neurotransmitter pathways and of their molecular organization may lead to advances in the pharmacotherapy of patients with vestibular dysfunction. ..
  53. Olympus FV 1000 Confocal Microscope for Neurobiology and Cellular Biology Researc
    Francisco Alvarez; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  54. Regulatory Molecules in Enteric Nervous System
    ALCMENE CHALAZONITIS; Fiscal Year: 2006
    ....
  55. Intrinsic Anatomy of the Circadian Rhythm System
    LAWRENCE MORIN; Fiscal Year: 2005
    ..There are neuron groups in the hamster SCN immunoreactive to GAGA, substance P, calbindin, calretinin, vasoactive intestinal polypeptide, vasopressin, cholecystokinin, and gastrin releasing peptide...
  56. Subcortical Estrogen Effect on The Hippocampus
    Csaba Leranth; Fiscal Year: 2005
    ..cholinergic and GABAergic septo-hippocampal neurons involved in mediating estrogenic effect to the hippocampus? and (d) Do SUM neurons mediate estrogenic effect to the hippocampus directly or indirectly, via the MSDB? ..
  57. SACRAL CREST CELLS AND ENTERIC NEURODEVELOPMENT
    Raj Kapur; Fiscal Year: 2005
    ..The results of this study will further our understanding of normal enteric neurodevelopment and congenital disorders of intestinal motility. ..
  58. Dynamic Molecular Mechanisms of Neurotransmitter Release
    FELIX SCHWEIZER; Fiscal Year: 2004
    ..By revealing novel mechanisms for the modulation of neurotransmitter release they may identify targets for therapeutic intervention in neurological diseases. ..
  59. CELLULAR BASIS FOR DOPAMINE ACTIONS IN PREFRONTAL CORTEX
    SUSAN SESACK; Fiscal Year: 2004
    ..Elucidating the synaptic organization of the mesocortical DA system will improve knowledge of the cellular mechanisms of DA modulation in cognition and the pathophysiology and treatment of major psychiatric disorders. ..