calretinin

Summary

Gene Symbol: calretinin
Description: calbindin 2
Alias: CAB29, CAL2, calretinin, 29 kDa calbindin, calbindin 2, (29kD, calretinin), calbindin D29K, testicular secretory protein Li 8
Species: human
Products:     calretinin

Top Publications

  1. Bertschy S, Genton C, Gotzos V. Selective immunocytochemical localisation of calretinin in the human ovary. Histochem Cell Biol. 1998;109:59-66 pubmed
    b>Calretinin is a calcium-binding protein which is primarily expressed by certain cells of the nervous system, both central and peripheral. Its presence in nonexcitable cells has been little studied...
  2. Henzi T, Blum W, Pfefferli M, Kawecki T, Salicio V, Schwaller B. SV40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis. Am J Pathol. 2009;174:2324-36 pubmed publisher
    The calcium-binding protein calretinin has emerged as a useful marker for the identification of mesotheliomas of the epithelioid and mixed types, but its putative role in tumor development has not been addressed previously...
  3. Camp A, Wijesinghe R. Calretinin: modulator of neuronal excitability. Int J Biochem Cell Biol. 2009;41:2118-21 pubmed publisher
    b>Calretinin is a member of the calcium-binding protein EF-hand family first identified in the retina...
  4. Barinka F, Druga R, Marusic P, Krsek P, Zamecnik J. Calretinin immunoreactivity in focal cortical dysplasias and in non-malformed epileptic cortex. Epilepsy Res. 2010;88:76-86 pubmed publisher
    ..Here, we wanted to show whether another interneuronal population, the calretinin immunoreactive (CR+) neurons, exhibits any change in human FCD...
  5. Raiko I, Sander I, Weber D, Raulf Heimsoth M, Gillissen A, Kollmeier J, et al. Development of an enzyme-linked immunosorbent assay for the detection of human calretinin in plasma and serum of mesothelioma patients. BMC Cancer. 2010;10:242 pubmed publisher
    b>Calretinin is one of the well-established immunohistochemical markers in the diagnostics of malignant mesothelioma (MM). Its utility as a diagnostic tool in human blood, however, is scarcely investigated...
  6. Yi P, Niu H, Gao Q, Wang F, Jia W, Chen Z, et al. [Pathologic features on gonadal changes of sexual developmental disorders in children]. Zhonghua Bing Li Xue Za Zhi. 2018;47:531-535 pubmed publisher
    ..Immunohistochemical stains were performed in 15 cases. D2-40, PLAP and CKIT were expressed in germ cells and Calretinin, WT1 and inhibin were positive in Setoli cells. SALL4 and OCT3/4 were positive in 3 cases...
  7. Takawira C, D Agostini S, Shenouda S, Persad R, Sergi C. Laboratory procedures update on Hirschsprung disease. J Pediatr Gastroenterol Nutr. 2015;60:598-605 pubmed publisher
    ..Recently, calretinin, a vitamin D-dependent calcium-binding protein with expression in ganglion cells and nerves, has been described ..
  8. Masliukov P, Budnik A, Nozdrachev A. [Developmental changes of neurotransmitter properties in sympathetic neurons]. Adv Gerontol. 2017;30:347-355 pubmed
    ..Separate groups of neurons differ in the content of neuronal calcium-binding proteins, such as calbindin, calretinin and parvalbumin and neurofilaments: low molecular weight, a medium molecular weight and high molecular weight...
  9. Fortofoiu M, Popescu D, Pădureanu V, Dobrinescu A, Dobrinescu A, Mită A, et al. Difficulty in positive diagnosis of ascites and in differential diagnosis of a pulmonary tumor. Rom J Morphol Embryol. 2017;58:1057-1064 pubmed
    ..peroxidase (HRP) method, as well as the antibodies: cytokeratin (CK) cocktail (AE1÷AE3), vimentin, calretinin, CK7, CK5÷6, CK20, epithelial specific antigen/epithelial cell adhesion molecule (Ep-CAM) (BerEP4), thyroid ..

More Information

Publications131 found, 100 shown here

  1. Atzpodien E, Jacobsen B, Funk J, Altmann B, Silva Munoz M, Singer T, et al. Advanced Clinical Imaging and Tissue-based Biomarkers of the Eye for Toxicology Studies in Minipigs. Toxicol Pathol. 2016;44:398-413 pubmed publisher
    ..of IHC and ISH markers on Davidson's fixed paraffin-embedded minipig eyes: neurofilament-160, neuronal nuclei, calretinin, protein kinase C-α, vimentin, glial fibrillary acidic protein, glutamine synthetase, ionized calcium-binding ..
  2. Ferrandina G, Palluzzi E, Fanfani F, Gentileschi S, Valentini A, Mattoli M, et al. Endometriosis-associated clear cell carcinoma arising in caesarean section scar: a case report and review of the literature. World J Surg Oncol. 2016;14:300 pubmed
    ..Tumor cells were positive for CK7 EMA, CKAE1/AE3, CD15, CA-125, while immunoreaction for Calretinin, WT1, estrogen, and progesterone receptors, cytokeratin 20, CD10, alpha fetoprotein, CDX2, TTF1, and ..
  3. Lin S, Chien Y, Chiang W, Liu Y, Lien C, Chen C. Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety. Eur J Neurosci. 2015;41:1553-68 pubmed publisher
    ..Colocalisation studies further revealed that ASIC4 was expressed mainly in three types of cells in the CNS: (i) calretinin (CR)-positive and/or vasoactive intestine peptide (VIP)-positive interneurons; (ii) neural/glial antigen 2 (NG2)-..
  4. Meek J, Yang J, Han V, Bell C. Morphological analysis of the mormyrid cerebellum using immunohistochemistry, with emphasis on the unusual neuronal organization of the valvula. J Comp Neurol. 2008;510:396-421 pubmed publisher
    ..1; the anchoring protein for GABA and glycine receptors, gephyrin; the calcium binding proteins calbindin and calretinin; the NR1 subunit of the N-methyl-D-aspartate glutamate receptor; the metabotropic glutamate receptors ..
  5. Atkins H, Lombardini E, Caudell D, Appt S, Dubois A, Cline J. Decidualization of Endometriosis in Macaques. Vet Pathol. 2016;53:1252-1258 pubmed
    ..estrogen receptor, desmin, cytokeratin, kermix P8, chorionic gonadotropin, human placental lactogen, and calretinin. The most common clinical signs were abdominal pain (4 of 6) and anorexia (2 of 6)...
  6. Allen P, DeBold J, Rios M, Kanarek R. Chronic high-dose creatine has opposing effects on depression-related gene expression and behavior in intact and sex hormone-treated gonadectomized male and female rats. Pharmacol Biochem Behav. 2015;130:22-33 pubmed publisher
    ..mRNAs measured, including brain-derived neurotrophic factor (BDNF), tyrosine kinase B, doublecortin, calretinin, and calbindin, were downregulated in sham males given 4% creatine, and BDNF, doublecortin, and calbindin mRNAs ..
  7. Chen J, Kuo H, Lee K, Tsai T. Global proteomic analysis of brain tissues in transient ischemia brain damage in rats. Int J Mol Sci. 2015;16:11873-91 pubmed publisher
    ..After an ischemic stroke, one protein spot, namely the calretinin (CALB2) protein, showed increased expression...
  8. Young R. Ovarian sex cord-stromal tumours and their mimics. Pathology. 2018;50:5-15 pubmed publisher
    ..The microcystic stromal tumour may mimic a steroid cell tumour or thecoma but unlike them is inhibin and calretinin negative, and stains for CD10 and ?-catenin...
  9. Murphy S, Zweyer M, Henry M, Meleady P, Mundegar R, Swandulla D, et al. Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy. Clin Proteomics. 2015;12:27 pubmed publisher
    ..animal model were represented by the glial fibrillary acidic protein GFAP, the neuronal Ca(2+)-binding protein calretinin, annexin AnxA5, vimentin, the neuron-specific enzyme ubiquitin carboxyl-terminal hydrolase isozyme L1, the ..
  10. Sanchez Ramos J, Song S, Sava V, Catlow B, Lin X, Mori T, et al. Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice. Neuroscience. 2009;163:55-72 pubmed publisher
    ..immunostaining in hippocampal CA1 and CA3 regions and augmented neurogenesis, evidenced by increased numbers of calretinin-expressing cells in dentate gyrus...
  11. Santos F, Pereira C, Sánchez Pérez A, Otero García M, Ma S, Gundlach A, et al. Comparative Distribution of Relaxin-3 Inputs and Calcium-Binding Protein-Positive Neurons in Rat Amygdala. Front Neuroanat. 2016;10:36 pubmed publisher
    ..the amygdala, relative to the distribution of neurons expressing the calcium-binding proteins, parvalbumin (PV), calretinin (CR) and/or calbindin...
  12. Taylor Walker G, Lynn S, Keeling E, Munday R, Johnston D, Page A, et al. The Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2). Exp Eye Res. 2016;153:110-121 pubmed publisher
    ..associated protein-2 (MAP-2) by confocal immunofluorescence which has not been shown before, but also calretinin which has not been reported previously...
  13. Lyu C, Mulder J, Barde S, Sahlholm K, Zeberg H, Nilsson J, et al. G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy. Mol Pain. 2015;11:44 pubmed publisher
    ..gene-related peptide, isolectin-B4 and neurofilament-200, and the calcium-binding proteins calbindin D28k, calretinin, parvalbumin and secretagogin. Both GIRK subunits were expressed in DRG neurons with nociceptive characteristics...
  14. Shimizu S, Funakoshi Y, Yoon H, Okuma T, Utsumi T, Ito N, et al. Small calcifying fibrous pseudotumor of the heart confined to the epicardium. Cardiovasc Pathol. 2015;24:191-3 pubmed publisher
    ..staining for CD34, but did not indicate positive staining for other pertinent antigens such as cytokeratins, calretinin, desmin, α-smooth muscle actin, ALK, and estrogen and progesterone receptors as well as IgG4 in plasma cells...
  15. Chintala S, Cheng M, Zhang X. Decreased Expression of DREAM Promotes the Degeneration of Retinal Neurons. PLoS ONE. 2015;10:e0127776 pubmed publisher
    ..Degeneration of amacrine cells and bipolar cells was determined by using antibodies against calretinin and protein kinase C (PKC)-alpha respectively...
  16. Andrici J, Farzin M, Clarkson A, Sioson L, Sheen A, Watson N, et al. Mutation specific immunohistochemistry is highly specific for the presence of calreticulin mutations in myeloproliferative neoplasms. Pathology. 2016;48:319-24 pubmed publisher
    ..immunohistochemistry for pathogenic CALR mutations using a commercially available mouse monoclonal antibody (clone CAL2)...
  17. Wang X, Liu C, Wang X, Gao F, Zhan R. Density and neurochemical profiles of neuronal nitric oxide synthase-expressing interneuron in the mouse basolateral amygdala. Brain Res. 2017;1663:106-113 pubmed publisher
    ..Proportions of nNOS-positive interneurons that expressed calbindin, calretinin, parvalbumin, somatostatin and neuropeptide Y were approximately 5.20%, 15.63%, 26.50%, 87.50% and 88...
  18. Calvani J, Lopez P, Sarnacki S, Molina T, Gibault L, Fabre M, et al. Solid-pseudopapillary neoplasms of the pancreas do not express major pancreatic markers in pediatric patients. Hum Pathol. 2018;: pubmed publisher
    ..2, chromogranin A, glucagon, insulin, somatostatin, ghrelin, pancreatic polypeptide, amylase, GFAP, calretinin, EPCAM and estrogen receptor ?...
  19. Bárez López S, Montero Pedrazuela A, Bosch García D, Venero C, Guadaño Ferraz A. Increased anxiety and fear memory in adult mice lacking type 2 deiodinase. Psychoneuroendocrinology. 2017;84:51-60 pubmed publisher
    ..We found a downregulation in the gene encoding for the calcium-binding protein calretinin (Calb2) in the amygdala of D2KO mice that could affect the GABAergic transmission...
  20. Tsuiji H, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, et al. TDP-43 accelerates age-dependent degeneration of interneurons. Sci Rep. 2017;7:14972 pubmed publisher
    ..Intriguingly, the aggregates contained some interneuron-specific proteins such as parvalbumin and calretinin, suggesting that GABAergic interneurons were degenerated in these mice...
  21. Godisela K, Reddy S, Kumar C, Saravanan N, Reddy P, Jablonski M, et al. Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome. Mol Vis. 2017;23:263-274 pubmed
    ..and increased levels of glial fibrillary acidic protein (GFAP), vascular endothelial growth factor (VEGF), and calretinin in WNIN/GR-Ob rats compared with the age-matched lean controls, further supporting cellular stress/damage and ..
  22. Haji Ali R, Khalife M, El Nounou G, Zuhri Yafi R, Nassar H, Aidibe Z, et al. Giant primary malignant mesothelioma of the liver: A case report. Int J Surg Case Rep. 2017;30:58-61 pubmed publisher
    ..Pathology showed a biphasic cellular pattern. In addition, the tumor cells were positive for Calretinin, Creatine Kinase (CK)5/6, CK7, CKAEI 1/3, Wilms Tumor protein (WT-1), and Vimentin, but were negative for Alpha ..
  23. FILIPOVIC D, Costina V, Perić I, Stanisavljević A, Findeisen P. Chronic fluoxetine treatment directs energy metabolism towards the citric acid cycle and oxidative phosphorylation in rat hippocampal nonsynaptic mitochondria. Brain Res. 2017;1659:41-54 pubmed publisher
    ..Of the identified proteins, the expressions of calretinin and parvalbumine were confirmed...
  24. Relan V, Morrison L, Parsonson K, Clarke B, Duhig E, Windsor M, et al. Phenotypes and karyotypes of human malignant mesothelioma cell lines. PLoS ONE. 2013;8:e58132 pubmed publisher
    ..At passage 2 to 6 all lines stained positively for calretinin and cytokeratin 19, and demonstrated capacity for anchorage-independent growth...
  25. Blake E, Sheridan T, Wang K, Takiuchi T, Kodama M, Sawada K, et al. Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature. Eur J Obstet Gynecol Reprod Biol. 2014;181:163-70 pubmed publisher
    ..0%). Mean tumor size was 6.2cm, and extra-uterine spread was seen in 7.0%. By immunohistochemistry, calretinin expression was significantly correlated with CAM5.2, inhibin, and progesterone receptor expression (all, p<0...
  26. Gangadharan V, Kuner R. Unravelling Spinal Circuits of Pain and Mechanical Allodynia. Neuron. 2015;87:673-5 pubmed publisher
    ..VGLUT3-expressing neurons and their polysynaptic connectivity to calretinin-expressing neurons are now identified as key determinants of the spinal circuitry underlying mechanical ..
  27. Zakowski W. Neurochemistry of the Anterior Thalamic Nuclei. Mol Neurobiol. 2017;54:5248-5263 pubmed publisher
    ..acid, glutamate and aspartate, acetylcholine, serotonin) and their receptors, (2) calcium-binding proteins (calretinin, calbindin, parvalbumin), and (3) others (cocaine- and amphetamine regulated transcript, enkephalins, substance ..
  28. Morris M, Soglio D, Ouimet A, Aspirot A, Patey N. A study of calretinin in Hirschsprung pathology, particularly in total colonic aganglionosis. J Pediatr Surg. 2013;48:1037-43 pubmed publisher
    b>Calretinin, a calcium-binding protein, has been reported to be an important new marker in Hirschsprung's disease (HD)...
  29. Károly N, Dobó E, Mihály A. Comparative immunohistochemical study of the effects of pilocarpine on the mossy cells, mossy fibres and inhibitory neurones in murine dentate gyrus. Acta Neurobiol Exp (Wars). 2015;75:220-37 pubmed
    ..NPY) immunohistochemistry, and the numbers of MCs were counted by means of immunohistochemistry, for calretinin (CR) in mice and calcitonin gene-related peptide (CGRP) in rats...
  30. Christel C, Schaer R, Wang S, Henzi T, Kreiner L, Grabs D, et al. Calretinin regulates Ca2+-dependent inactivation and facilitation of Ca(v)2.1 Ca2+ channels through a direct interaction with the ?12.1 subunit. J Biol Chem. 2012;287:39766-75 pubmed publisher
    ..Here, we show that calretinin (CR), a Ca(2+)-binding protein highly expressed in subpopulations of neurons in the brain, inhibits CDI and ..
  31. Kresoja Rakic J, Sulemani M, Kirschner M, Ronner M, Reid G, Kao S, et al. Posttranscriptional Regulation Controls Calretinin Expression in Malignant Pleural Mesothelioma. Front Genet. 2017;8:70 pubmed publisher
    b>Calretinin (CALB2) is a diagnostic and prognostic marker in malignant pleural mesothelioma (MPM). We previously reported that calretinin expression is regulated at the mRNA level...
  32. DeVilliers P, Liu H, Suggs C, Simmons D, Daly B, Zhang S, et al. Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor. Am J Surg Pathol. 2008;32:256-60 pubmed publisher
    ..The expression of calretinin [calbindin2 (CALB2)] was investigated on both ameloblastoma and KCOT...
  33. Kresoja Rakic J, Kapaklikaya E, Ziltener G, Dalcher D, Santoro R, Christensen B, et al. Identification of cis- and trans-acting elements regulating calretinin expression in mesothelioma cells. Oncotarget. 2016;7:21272-86 pubmed publisher
    b>Calretinin (CALB2) is a diagnostic marker for epithelioid mesothelioma. It is also a prognostic marker since patients with tumors expressing high calretinin levels have better overall survival...
  34. Thapa B, Walkiewicz M, Murone C, Asadi K, Deb S, BARNETT S, et al. Calretinin but not caveolin-1 correlates with tumour histology and survival in malignant mesothelioma. Pathology. 2016;48:660-665 pubmed publisher
    Malignant mesothelioma (MM) continues to be a disease with poor prognosis and limited treatment options. Calretinin and caveolin-1 expression by tumour in MM have recently been described to be associated with tumour histology, ..
  35. Yoshida A, Goto K, Kodaira M, Kobayashi E, Kawamoto H, Mori T, et al. CIC-rearranged Sarcomas: A Study of 20 Cases and Comparisons With Ewing Sarcomas. Am J Surg Pathol. 2016;40:313-23 pubmed publisher
    ..Distinguishing immunohistochemical features included heterogenous CD99 reactivity, nuclear WT1 expression, and calretinin expression in the CIC-rearranged sarcomas and NKX2.2 expression in the Ewing sarcomas...
  36. Bayguinov P, Ma Y, Gao Y, Zhao X, Jackson M. Imaging Voltage in Genetically Defined Neuronal Subpopulations with a Cre Recombinase-Targeted Hybrid Voltage Sensor. J Neurosci. 2017;37:9305-9319 pubmed publisher
    ..this mouse with Cre drivers generated double transgenics expressing hVOS probe in GABAergic, parvalbumin, and calretinin interneurons, as well as hilar mossy cells, new adult-born neurons, and recently active neurons...
  37. Zhang M, Barde S, Szodorai E, Josephson A, Mitsios N, Watanabe M, et al. Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord. Brain Struct Funct. 2016;221:3803-23 pubmed publisher
    ..Rodent ependymal cells expressed calbindin-D28k. In humans, they instead were NECAB2(+) and/or calretinin(+)...
  38. Najdzion J. Cocaine- and amphetamine-regulated transcript peptide and calcium binding proteins immunoreactivity in the superficial layers of the superior colliculus in the guinea pig: Implications for visual sensory processing. J Chem Neuroanat. 2017;79:66-79 pubmed publisher
    ..of cocaine- and amphetamine-regulated transcript peptide (CART) and three calcium-binding proteins (calbindin, calretinin and parvalbumin) in the superficial layers of the superior colliculus (SCs) in the guinea pig...
  39. Koperski Ł, Szczepankiewicz B, Pihowicz P, Fus Ł, Wolinska E, Gornicka B. Adrenal cyst with both Müllerian and mesothelial differentiation- a clinicopathological and immunohistochemical study with implications for histogenesis. Histol Histopathol. 2017;32:1141-1149 pubmed publisher
    ..epithelium were strongly positive for PAX8, ER, Ep-CAM and EMA, focally positive for PR, and were negative for calretinin, whereas the cells of the flat-to-cuboidal lining were positive for calretinin and podoplanin and showed only a ..
  40. Bar Shira Maymon B, Yavetz H, Yogev L, Kleiman S, Lifschitz Mercer B, Schreiber L, et al. Detection of calretinin expression in abnormal immature Sertoli cells in non-obstructive azoospermia. Acta Histochem. 2005;107:105-12 pubmed
    The current study identified for the first time calretinin expression in abnormal Sertoli cells of azoospermic men who underwent testicular biopsy for sperm recovery and application of the retrieved sperm by in vitro fertilization ..
  41. Ahn J, Chen B, Yan B, Park J, Kang I, Lee T, et al. Effects of long?term scopolamine treatment on cognitive deficits and calcium binding proteins immunoreactivities in the mouse hippocampus. Mol Med Rep. 2018;17:293-299 pubmed publisher
    ..on numerous hippocampal interneurons containing calcium binding proteins (CBPs), including calbindin D?28k (CB), calretinin (CR) and parvalbumin (PV)...
  42. Smiley J, Hackett T, Bleiwas C, Petkova E, Stankov A, Mann J, et al. Reduced GABA neuron density in auditory cerebral cortex of subjects with major depressive disorder. J Chem Neuroanat. 2016;76:108-121 pubmed publisher
    ..In MDD, densities of GABAergic interneurons immunolabeled for calretinin (CR) and calbindin (CB) were 23-29% lower than non-psychiatric controls in both areas...
  43. Stewart C, Crook M, Tan A. SF1 immunohistochemistry is useful in differentiating uterine tumours resembling sex cord-stromal tumours from potential histological mimics. Pathology. 2016;48:434-40 pubmed publisher
    ..All cases were stained immunohistochemically for SF1, FOXL2, calretinin and inhibin, and for the less specific markers smooth muscle actin, desmin, CD10, CD56, CD99, cytokeratin, ..
  44. Ochs C, Suntres T, Zygowska A, Pitcher T, Zielinski B. Organization of glomerular territories in the olfactory bulb of post-embryonic wild chinook salmon Oncorhynchus tshawytscha. J Morphol. 2017;278:464-474 pubmed publisher
    ..sensory neurons to amino acids, corresponding glomeruli in the lateral bulbar region were mapped using anti-calretinin. The dorsolateral territory, distinct glomeruli of the lateral glomerular territory and the ventromedial ..
  45. Uesaka T, Nagashimada M, Enomoto H. Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. J Neurosci. 2015;35:9879-88 pubmed publisher
    ..up to 20% of enteric neurons in the large intestine and gave rise mainly to restricted neuronal subtypes, calretinin-expressing neurons...
  46. Alshammari M, Alshammari T, Nenov M, Scala F, Laezza F. Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus. Mol Neurobiol. 2016;53:7254-7270 pubmed
    ..This results in an increase in the late immature and early mature population of DCX and calretinin (CR)-positive neurons...
  47. Adorjan I, Ahmed B, Feher V, Torso M, Krug K, Esiri M, et al. Calretinin interneuron density in the caudate nucleus is lower in autism spectrum disorder. Brain. 2017;140:2028-2040 pubmed publisher
    ..We used immunohistochemistry for calretinin and neuropeptide Y in 24 age- and gender-matched patients with autism spectrum disorder and control subjects ..
  48. Unal G, Joshi A, Viney T, Kis V, Somogyi P. Synaptic Targets of Medial Septal Projections in the Hippocampus and Extrahippocampal Cortices of the Mouse. J Neurosci. 2015;35:15812-26 pubmed publisher
    ..somata or dendrites immunopositive for interneuron cell-type molecular markers, such as parvalbumin, calbindin, calretinin, N-terminal EF-hand calcium-binding protein 1, cholecystokinin, reelin, or a combination of these molecules...
  49. Fazel Darbandi S, Poitras L, Monis S, Lindtner S, Yu M, Hatch G, et al. Functional consequences of I56ii Dlx enhancer deletion in the developing mouse forebrain. Dev Biol. 2016;: pubmed publisher
    ..I56ii reduces the expression of the ISLET1 and CTIP2 in the striatum and disrupts the number of parvalbumin and calretinin expressing cells in the adult somatosensory cortex of the ?I56ii mice...
  50. Wild J. Dorsal pallidal neurons directly link the nidopallium and midbrain in the zebra finch (Taeniopygia guttata). J Comp Neurol. 2017;525:1731-1742 pubmed publisher
    ..The size and morphology of these neurons were similar to those of large pallidal neurons labeled by calretinin immunoreactivity, which could be co-localized to the same cells...
  51. Ruby K, Falvey K, Kulesza R. Abnormal neuronal morphology and neurochemistry in the auditory brainstem of Fmr1 knockout rats. Neuroscience. 2015;303:285-98 pubmed publisher
    ..decarboxylase (GAD67) in neurons of the superior paraolivary nucleus (SPON) and a reduction in the number of calretinin-immunoreactive terminals associated with neurons of the medial nucleus of the trapezoid body (MNTB)...
  52. Ludwig K, Volpe A, Guzzardo V, Santoro L, Midrio P, Gamba P, et al. Anti-Glypican 3, a Novel Ancillary Maker in the Histological Assessment of Hirschsprung's Disease. J Pediatr Gastroenterol Nutr. 2016;62:692-7 pubmed publisher
    ..The presence/absence of ganglion cells was evaluated retrospectively by immunohistochemical staining for calretinin and GPC-3 in tissue specimens; a total of 15 patients who underwent colectomy (total or sub-total) for ..
  53. Mîndrilă I, Buteică S, Mihaiescu D, Burada F, Mîndrilă B, Predoi M, et al. Magnetic nanoparticles-based therapy for malignant mesothelioma. Rom J Morphol Embryol. 2017;58:457-463 pubmed
    ..In order to assess the human MPM xenograft growth characteristics, calretinin, HBME-1 (Hector Battifora mesothelial epitope-1), and cytokeratins immunohistochemical stainings were performed...
  54. Freire M, Faber J, Lemos N, Santos J, Cavalcanti P, Lima R, et al. Distribution and Morphology of Calcium-Binding Proteins Immunoreactive Neurons following Chronic Tungsten Multielectrode Implants. PLoS ONE. 2015;10:e0130354 pubmed publisher
    ..impact the distribution and morphology of interneurons reactive to calcium-binding proteins calbindin (CB), calretinin (CR) and parvalbumin (PV) across the rat's motor cortex...
  55. Muller C, Hobeika C, Montalva L, Berrebi D, Bonnard A. Calretinin Variant in Hirschsprung Disease: Pretransitional Sign and Surgical Planning. Eur J Pediatr Surg. 2016;26:449-453 pubmed
    b>Objectives Calretinin immunohistochemistry (IHC) with slight submucosal positivity (variant) has been reported in short forms of Hirschsprung disease (HD)...
  56. Zhang X, Sullivan C, Kratz M, Kasten M, Maness P, Manis P. NCAM Regulates Inhibition and Excitability in Layer 2/3 Pyramidal Cells of Anterior Cingulate Cortex. Front Neural Circuits. 2017;11:19 pubmed publisher
    ..mice, NCAM is expressed postnatally at perisomatic synaptic puncta of EYFP-labeled parvalbumin, somatostatin and calretinin-positive interneurons, and in the neuropil in the anterior cingulate cortex (ACC)...
  57. Gulyás A, Freund T, Káli S. The Effects of Realistic Synaptic Distribution and 3D Geometry on Signal Integration and Extracellular Field Generation of Hippocampal Pyramidal Cells and Inhibitory Neurons. Front Neural Circuits. 2016;10:88 pubmed
    ..b>Calretinin-containing interneurons were found to be electrotonically extended, which suggests the possibility of complex ..
  58. Guo Z, Sun W, Michele Y, Zhang J, Hu D, Su H, et al. [Loss of BRCA associated protein 1 expression in malignant mesothelioma and its diagnostic application]. Zhonghua Bing Li Xue Za Zhi. 2017;46:699-703 pubmed publisher
    ..A differential diagnosis antibody panel, including calretinin, WT1, CK5/6, D2-40, CAM5.2, CEA, TTF1, Napsin A, p63 and p40 was tested in all cases...
  59. Karadi K, Janszky J, Gyimesi C, Horvath Z, Lucza T, Doczi T, et al. Correlation between calbindin expression in granule cells of the resected hippocampal dentate gyrus and verbal memory in temporal lobe epilepsy. Epilepsy Behav. 2012;25:110-9 pubmed publisher
  60. Hoffman L, Choy K, Sultemeier D, Simmons D. Oncomodulin Expression Reveals New Insights into the Cellular Organization of the Murine Utricle Striola. J Assoc Res Otolaryngol. 2018;19:33-51 pubmed publisher
    ..Immunohistochemistry was conducted using antibodies to OCM, calretinin, and ?3-tubulin...
  61. Kim K, Lee J, Bae J. Significant growth of adrenal lymphangioma: A case report and review of the literature. Int J Surg Case Rep. 2015;17:48-50 pubmed publisher
    ..On immunohistochemical examination, D2-40 cytoplastic staining was positive, whereas calretinin and CD34 were negative, thus, confirming their lymphatic nature...
  62. Hoeijmakers L, Meerhoff G, de Vries J, Ruigrok S, van Dam A, Van Leuven F, et al. The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis. Neurobiol Aging. 2018;61:112-123 pubmed publisher
    ..Notably, aging reduced the AHN marker doublecortin, but not calretinin, to a similar extent in wild-type and APP.V717I mice between 10 and 26 months...
  63. Blum W, Pecze L, Felley Bosco E, Wu L, de Perrot M, Schwaller B. Stem Cell Factor-Based Identification and Functional Properties of In Vitro-Selected Subpopulations of Malignant Mesothelioma Cells. Stem Cell Reports. 2017;8:1005-1017 pubmed publisher
    ..In contrast, downregulation of calretinin strongly decreased proliferation and viability of both populations...
  64. Qiu T, Teng Y, Tong J, Tao W, Xu L. Recurrent female adnexal tumor of probably Wolffian origin: A case report. Taiwan J Obstet Gynecol. 2017;56:382-384 pubmed publisher
    ..Immunohistochemistry revealed that the lesions were inhibin A, calretinin, estrogen receptor, progesterone receptor, cluster of differentiation 99, and Pax2 positive...
  65. Cabibi D, Tutino R, Salamone G, Cocorullo G, Agrusa A, Gulotta G. Diffuse malignant biphasic peritoneal mesothelioma with cystic areas. Ann Ital Chir. 2016;87: pubmed
    ..Atypia and mitoses were very scanty. EMA, vimentin, CK5/6, D2-40, calretinin and P53 were positive and desmin was negative in both epithelial and spindle areas, including the ones ..
  66. Guo Z, Carbone M, Zhang X, Su D, Sun W, Lou J, et al. Improving the Accuracy of Mesothelioma Diagnosis in China. J Thorac Oncol. 2017;12:714-723 pubmed publisher
    ..MMs were characterized by tumor cells showing nuclear Wilms tumor 1 and calretinin staining and by strong membranous staining for cytokeratin CAM5.2...
  67. Zetzmann K, Strehl J, Geppert C, Kuerten S, Jabari S, Brehmer A. Calbindin D28k-Immunoreactivity in Human Enteric Neurons. Int J Mol Sci. 2018;19: pubmed publisher
    ..evaluate (1) the proportion of CALB? neurons in the total neuron population, (2) the colocalization of CALB with calretinin (CALR), somatostatin (SOM) and vasoactive intestinal peptide (VIP) and (3) the morphology of CALB+ ..
  68. Polinas M, Burrai G, Marras V, Ariu R, Zedda M, Pau S, et al. Co-occurrence of a metastatic mammary liposarcoma and an ovarian sex-cord stromal tumor in a dog. Res Vet Sci. 2016;109:157-160 pubmed publisher
    ..Moreover, the ovarian tumor was positive for calretinin. This is the first report to the authors' knowledge, of the co-occurrence of a pleomorphic liposarcoma of the ..
  69. Hashemi E, Ariza J, Rogers H, Noctor S, Martinez Cerdeno V. The Number of Parvalbumin-Expressing Interneurons Is Decreased in the Medial Prefrontal Cortex in Autism. Cereb Cortex. 2017;27:1931-1943 pubmed publisher
    ..into 3 subpopulations based on expression of the calcium-binding proteins parvalbumin, calbindin, or calretinin. We quantified the number of each interneuron subtype in postmortem neocortical tissue from 11 autistic cases ..
  70. Weissferdt A, Kalhor N, Rodriguez Canales J, Fujimoto J, Wistuba I, Moran C. Spindle cell and pleomorphic ("sarcomatoid") carcinomas of the lung: an immunohistochemical analysis of 86 cases. Hum Pathol. 2017;59:1-9 pubmed publisher
    ..2, cytokeratin (CK) 7, thyroid transcription factor 1, napsin A, CK5/6, p40, desmocollin 3, Sox2, calretinin, and D2-40. The percentage of positive tumor cells as well as the staining intensity were evaluated and scored...
  71. Galinsky R, Davidson J, Lear C, Bennet L, Green C, Gunn A. Connexin hemichannel blockade improves survival of striatal GABA-ergic neurons after global cerebral ischaemia in term-equivalent fetal sheep. Sci Rep. 2017;7:6304 pubmed publisher
    ..Cerebral ischaemia was associated with reduced numbers of calbindin-28k, calretinin, parvalbumin and GAD positive striatal neurons (P?<?0.05 ischaemia?+?vehicle, n?=?6 vs...
  72. Murueta Goyena A, Ortuzar N, Gargiulo P, Lafuente J, Bengoetxea H. Short-Term Exposure to Enriched Environment in Adult Rats Restores MK-801-Induced Cognitive Deficits and GABAergic Interneuron Immunoreactivity Loss. Mol Neurobiol. 2018;55:26-41 pubmed publisher
    ..We quantified different interneuron populations based on their calcium-binding protein expression (parvalbumin, calretinin, and calbindin), glutamic acid decarboxylase 67, and neuronal nuclei-positive cells by means of unbiased ..
  73. Kuehn S, Rodust C, Stute G, Grotegut P, Meißner W, Reinehr S, et al. Concentration-Dependent Inner Retina Layer Damage and Optic Nerve Degeneration in a NMDA Model. J Mol Neurosci. 2017;63:283-299 pubmed publisher
    ..At days 3 and 14, Brn-3a+ RGCs were degenerated. A damage of calretinin+ amacrine cells was also recognized at day 14...
  74. Serafini S, Santos M, Aoun Tannuri A, Zerbini M, de Mendonça Coelho M, de Oliveira Gonçalves J, et al. Is hematoxylin-eosin staining in rectal mucosal and submucosal biopsies still useful for the diagnosis of Hirschsprung disease?. Diagn Pathol. 2017;12:84 pubmed publisher
    ..of the current investigation were to evaluate the concordance of the results obtained by HE staining and the calretinin method with acetylcholinesterase (AChE) activity in fragments of mucosa and submucosa in the diagnosis of HD...
  75. Acebo E, Val Bernal J, Gómez Román J. Thrombomodulin, calretinin and c-kit (CD117) expression in cardiac myxoma. Histol Histopathol. 2001;16:1031-6 pubmed publisher
    ..This study comprised the immunoreactivity of the tumors for thrombomodulin, calretinin and and c-kit (CD117)...
  76. Massouh M, Wallman M, Pourcher E, Parent A. The fate of the large striatal interneurons expressing calretinin in Huntington's disease. Neurosci Res. 2008;62:216-24 pubmed publisher
    ..However, little is known about the fate of the large interneurons that express calretinin (Cr) in HD...
  77. Wooff J, Weinreb I, Perez Ordonez B, Magee J, Bullock M. Calretinin staining facilitates differentiation of olfactory neuroblastoma from other small round blue cell tumors in the sinonasal tract. Am J Surg Pathol. 2011;35:1786-93 pubmed publisher
    ..The purpose of this study is to determine the usefulness of calretinin and p63 as an aid to distinguish ONB from other sinonasal SRBCTs...
  78. Xu G, Zhang J. [Giant solitary fibrous tumor of the pleura: A case report and literature review]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2016;41:1111-1116 pubmed
    ..Immunohistochemical results showed: CD34 (+), cytokeratin (-), cytokeratin 5/6 (-), calretinin (-), epithelial membrane antigen(-), mesothelial cell (-), vimentin (++), Wilm's tumor-1 (+), Bcl-2 (+), CD56 (-)..
  79. Masliukov P, Moiseev K, Budnik A, Nozdrachev A, Timmermans J. Development of Calbindin- and Calretinin-Immunopositive Neurons in the Enteric Ganglia of Rats. Cell Mol Neurobiol. 2017;37:1257-1267 pubmed publisher
    Calbindin D28 K (CB) and calretinin (CR) are the members of the EF-hand family of calcium-binding proteins that are expressed in neurons and nerve fibers of the enteric nervous system...
  80. Melotti A, Daga A, Marubbi D, Zunino A, Mutti L, Corte G. In vitro and in vivo characterization of highly purified human mesothelioma derived cells. BMC Cancer. 2010;10:54 pubmed publisher
    ..Our work was aimed to establish from fresh human pleural mesothelioma samples cell cultures maintaining tumorigenic properties...
  81. Boscia F, Casamassa A, Secondo A, Esposito A, Pannaccione A, Sirabella R, et al. NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. Mol Neurobiol. 2016;53:1365-76 pubmed publisher
    Recently, the Na(+)/Ca(+2) exchanger NCX1 and the calcium binding protein calretinin have emerged as new molecular effectors of delayed preconditioning in the brain...
  82. Sahin N, Akatli A, Çelik M, Ulutas H, Samdanci E, Colak C. The Role of CD90 in the Differential Diagnosis of Pleural Malignant Mesothelioma, Pulmonary Carcinoma and Comparison with Calretının. Pathol Oncol Res. 2017;23:487-491 pubmed publisher
    ..differential diagnosis of MM and lung carcinoma, its prognostic significance and compare its value with that of Calretinin. Ninety pathology specimens including MM (n:30), pulmonary adenocarcinoma (n:30) and pulmonary squamous cell ..
  83. Altobelli G, Pentimalli F, D Armiento M, Van Noorden S, Cimini V. Calretinin Immunoreactivity in the Human Testis Throughout Fetal Life. J Cell Physiol. 2017;232:1872-1878 pubmed publisher
    ..Calcium homeostasis and signaling rely on many calcium-binding proteins including calretinin, of the "EF-hand" protein family...
  84. Kuehn S, Hurst J, Rensinghoff F, Tsai T, Grauthoff S, Satgunarajah Y, et al. Degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model. Exp Eye Res. 2017;155:107-120 pubmed publisher
    ..A loss of retinal ganglion cells (RGCs, Brn-3a), amacrine cells (calretinin) and bipolar cells (PKC?) was observed...
  85. Guinard Samuel V, Bonnard A, De Lagausie P, Philippe Chomette P, Alberti C, El Ghoneimi A, et al. Calretinin immunohistochemistry: a simple and efficient tool to diagnose Hirschsprung disease. Mod Pathol. 2009;22:1379-84 pubmed publisher
    ..The aim of this study was to assess the diagnostic value of calretinin immunochemistry as a simple and reliable method in the diagnosis of HD...
  86. Michalova K, Michal M, Kazakov D, Sedivcová M, Hes O, Hadravsky L, et al. Primary signet ring stromal tumor of the testis: a study of 13 cases indicating their phenotypic and genotypic analogy to pancreatic solid pseudopapillary neoplasm. Hum Pathol. 2017;67:85-93 pubmed publisher
    ..claudin 7, ?-1-antitrypsin, CD56, and neuron-specific enolase and negativity for chromogranin, inhibin, calretinin, SF-1, NANOG, OCT3/4, and SALL4...
  87. Boulanger J, Messier C. Oligodendrocyte progenitor cells are paired with GABA neurons in the mouse dorsal cortex: Unbiased stereological analysis. Neuroscience. 2017;362:127-140 pubmed publisher
    ..cortex, GABAergic interneurons represent the most common neuronal component of the pairs, and that calbindin, calretinin and parvalbumin GABAergic interneurons found in the cortex take part in these pairs...
  88. Homann V, Kinne Saffran E, Arnold W, Gaengler P, Kinne R. Calcium transport in human salivary glands: a proposed model of calcium secretion into saliva. Histochem Cell Biol. 2006;125:583-91 pubmed
  89. De Santis L, Gandolfi F, Pennarossa G, Maffei S, Gismano E, Intra G, et al. Expression and intracytoplasmic distribution of staufen and calreticulin in maturing human oocytes. J Assist Reprod Genet. 2015;32:645-52 pubmed publisher
    ..Moreover, the unique disposition of CALR at the MII spindle uncovers a physical interaction with endoplasmic reticulum that may mediate cytoskeletal remodelling during oocyte maturation. ..
  90. da Silva M, Marosti A, Mendes C, Palombit K, Castelucci P. Submucosal neurons and enteric glial cells expressing the P2X7 receptor in rat experimental colitis. Acta Histochem. 2017;119:481-494 pubmed publisher
    ..of the P2X7 receptor with calbindin (marker for intrinsic primary afferent neurons, IPANs, submucosal plexus), calretinin (marker for secretory and vasodilator neurons of the submucosal plexus), HuC/D and S100? was performed in the ..
  91. Dinday M, Girskis K, Lee S, Baraban S, Hunt R. PAFAH1B1 haploinsufficiency disrupts GABA neurons and synaptic E/I balance in the dentate gyrus. Sci Rep. 2017;7:8269 pubmed publisher
    ..density of parvalbumin- and somatostatin-positive interneurons in dentate gyrus, but no change in density of calretinin interneurons...
  92. Qin S, Ware S, Waclaw R, Campbell K. Septal contributions to olfactory bulb interneuron diversity in the embryonic mouse telencephalon: role of the homeobox gene Gsx2. Neural Dev. 2017;12:13 pubmed publisher
    ..Notably, the embryonic septum was found to give rise largely to the calretinin+ (CR+) GL subtype, while the dLGE was more diverse, generating all major GL subpopulations ..