C2

Summary

Gene Symbol: C2
Description: complement component 2
Alias: CO2, C3/C5 convertase, complement C2, complement component C2
Species: human

Top Publications

  1. pmc Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
    Bert Gold
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland 21702, USA
    Nat Genet 38:458-62. 2006
  2. doi Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families
    M C Eike
    Institute of Immunology, Rikshospitalet University Hospital, Oslo, Norway
    Genes Immun 10:141-50. 2009
  3. pmc C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes
    Johanna Jakobsdottir
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 3:e2199. 2008
  4. pmc Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
    Johanna M Seddon
    Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts 02111, USA
    Invest Ophthalmol Vis Sci 50:2044-53. 2009
  5. pmc Complement component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort
    Gareth J McKay
    Centre for Vision and Vascular Sciences, Queen s University of Belfast, Belfast, Northern Ireland BT12 6BA, UK
    Mol Vis 16:194-9. 2010
  6. pmc Human immunodeficiency virus type 1 induces expression of complement factors in human astrocytes
    C Speth
    Ludwig Boltzmann Institute for AIDS Research and Institute for Hygiene and Social Medicine, University of Innsbruck, Innsbruck, Austria
    J Virol 75:2604-15. 2001
  7. doi Further assessment of the complement component 2 and factor B region associated with age-related macular degeneration
    Gareth J McKay
    Centre for Vision Sciences, Queen s University of Belfast, Belfast, Northern Ireland, United Kingdom
    Invest Ophthalmol Vis Sci 50:533-9. 2009
  8. ncbi Responses of the red blood cells from two high-energy-demand teleosts, yellowfin tuna (Thunnus albacares) and skipjack tuna (Katsuwonus pelamis), to catecholamines
    T E Lowe
    Joint Institute for Marine and Atmospheric Research, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu 96822, USA
    J Comp Physiol B 168:405-18. 1998
  9. ncbi [General environmental pollutants and passive smoking]
    R Meister
    Marienkrankenhaus, , Asthma und Allergie, Bad Lippspringe
    Pneumologie 44:378-86. 1990
  10. ncbi Trace gases generated in closed plant cultivation systems and their effects on plant growth
    A Tani
    Osaka Prefecture University, Sakai
    Biol Sci Space 9:314-26. 1995

Detail Information

Publications236 found, 100 shown here

  1. pmc Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
    Bert Gold
    Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland 21702, USA
    Nat Genet 38:458-62. 2006
    ..We screened factor B (BF) and complement component 2 (C2) genes, located in the major histocompatibility complex class III region, for genetic variation in two independent ..
  2. doi Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families
    M C Eike
    Institute of Immunology, Rikshospitalet University Hospital, Oslo, Norway
    Genes Immun 10:141-50. 2009
    ..Our results illustrate the importance of a comprehensive adjustment for LD effects when performing association studies in this complex...
  3. pmc C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes
    Johanna Jakobsdottir
    Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 3:e2199. 2008
    ..Two other complement pathway genes, the closely linked complement component receptor (C2) and complement factor B (CFB), were recently shown to harbor variants associated with ARM.
  4. pmc Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
    Johanna M Seddon
    Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts 02111, USA
    Invest Ophthalmol Vis Sci 50:2044-53. 2009
    ..The joint effects of genetic, ocular, and environmental variables were evaluated and predictive models for prevalence and incidence of AMD were assessed...
  5. pmc Complement component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort
    Gareth J McKay
    Centre for Vision and Vascular Sciences, Queen s University of Belfast, Belfast, Northern Ireland BT12 6BA, UK
    Mol Vis 16:194-9. 2010
    ..We assess its effect on AMD risk in a Northern Irish sample, test for gene-gene and gene-environment interaction, and review a risk prediction model...
  6. pmc Human immunodeficiency virus type 1 induces expression of complement factors in human astrocytes
    C Speth
    Ludwig Boltzmann Institute for AIDS Research and Institute for Hygiene and Social Medicine, University of Innsbruck, Innsbruck, Austria
    J Virol 75:2604-15. 2001
    ..lines and primary astrocytes with HIV-1 induced a marked upregulation of the expression of the complement factors C2 and C3. The synthesis of other secreted or membrane-bound complement proteins was not found to be altered...
  7. doi Further assessment of the complement component 2 and factor B region associated with age-related macular degeneration
    Gareth J McKay
    Centre for Vision Sciences, Queen s University of Belfast, Belfast, Northern Ireland, United Kingdom
    Invest Ophthalmol Vis Sci 50:533-9. 2009
    ....
  8. ncbi Responses of the red blood cells from two high-energy-demand teleosts, yellowfin tuna (Thunnus albacares) and skipjack tuna (Katsuwonus pelamis), to catecholamines
    T E Lowe
    Joint Institute for Marine and Atmospheric Research, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu 96822, USA
    J Comp Physiol B 168:405-18. 1998
    ..We also use our data to investigate the extent of the Haldane effect and its relationship to blood O2 and CO2 transport in yellowfin tuna. Yellowfin tuna blood shows a large Haldane effect; intracellular pH increases 0...
  9. ncbi [General environmental pollutants and passive smoking]
    R Meister
    Marienkrankenhaus, , Asthma und Allergie, Bad Lippspringe
    Pneumologie 44:378-86. 1990
    ..Interiors are characterised by an accumulation of CO2, CO, NO2, dust aerosols and various organic substances such as benzene, benzypyrene, formaldehyde, nitrosamines etc...
  10. ncbi Trace gases generated in closed plant cultivation systems and their effects on plant growth
    A Tani
    Osaka Prefecture University, Sakai
    Biol Sci Space 9:314-26. 1995
    ..Ethylene release rates of intact lettuce plant were affected by cultivation conditions such as ambient CO2 concentration, light intensity and light/dark period...
  11. pmc A role for endothelin in bicuculline-induced neurogenic pulmonary oedema in rats
    C Herbst
    Department of Pharmacology and Toxicology, Ruhr University, Bochum, Germany
    Br J Pharmacol 115:753-60. 1995
    ..49 +/- 1.20 kPa to 7.51 +/- 2.21 kPa (P < 0.01) and arterial CO2 partial pressure (PaCO2) significantly increased from 4.64 +/- 0.56 kPa to 8.15 +/- 0.99 kPa (P < 0.01)...
  12. ncbi [Effects of angiotensin II and pressure on cellular fibronectin in the vascular wall in organotypic culture]
    N Bardy
    INSERM U141, , Paris
    Arch Mal Coeur Vaiss 87:991-5. 1994
    ..Vessels were pressurized at 0, 80 or 150 mmHg, and kept for 3 days in incubator at 37 degrees C under 5% CO2. De novo synthesis of fibronectin was detected by immunofluorescence using anti-cellular fibronectin antibodies (1/..
  13. pmc Loss of contractile activity of endothelin-1 induced by electrical field stimulation-generated free radicals
    N Yasuda
    Department of Pharmacology, Institute of Basic Medical Sciences, University of Tsukuba, Japan
    Br J Pharmacol 113:21-8. 1994
    ..5. The exchange of 95% O2/5% CO2 gas for 95% N2/5% CO2 gas significantly inhibited the EFS-induced decrease in release of ir-ET-1. 6...
  14. pmc Raman spectroscopy of DNA-metal complexes. I. Interactions and conformational effects of the divalent cations: Mg, Ca, Sr, Ba, Mn, Co, Ni, Cu, Pd, and Cd
    J Duguid
    Department of Biochemistry, University of Minnesota, St Paul 55108
    Biophys J 65:1916-28. 1993
    Interactions of divalent metal cations (Mg2+, Ca2+, Ba2+, Sr2+, Mn2+, Co2+, Ni2+, Cu2+, Pd2+, and Cd2+) with DNA have been investigated by laser Raman spectroscopy...
  15. pmc Hyperpolarization by opioids acting on mu-receptors of a sub-population of rat periaqueductal gray neurones in vitro
    B Chieng
    Department of Pharmacology, University of Sydney, NSW, Australia
    Br J Pharmacol 113:121-8. 1994
    ..1 microM tetrodotoxin + 4 mM Co2+, n = 3). 3...
  16. ncbi Effects of very high antibiotic concentrations on human intervertebral disc cell proliferation, viability, and metabolism in vitro
    G L Hoelscher
    Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
    Spine (Phila Pa 1976) 25:1871-7. 2000
    ..metabolism because it reflects the excretion over time of acidic products such as lactic acid from glycolysis and CO2 from cellular respiration...
  17. ncbi Relationship between six-minute walking test and pulmonary function and ventilatory drive in patients with airflow limitation
    L L Chiang
    Second Section of Thoracic Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Fu-Shin Street, Kweishan, Taoyuan, Taiwan
    Chang Gung Med J 24:159-66. 2001
    ..1 were measured before drawing blood gases. Then, a 6-minute walking test with pulse-oxymetry and end tidal CO2 monitoring was performed. Ventilation efficiency (O2SATp & ETCO2) was recorded every 6 seconds during exercise...
  18. ncbi Milk intake, growth and energy consumption in pups of ice-breeding grey seals (Halichoerus grypus) from the Gulf of St. Lawrence, Canada
    C Lydersen
    University of Oslo, Department of Biology, Norway
    J Comp Physiol B 164:585-92. 1995
    ..The total water influx was measured to be 43.23 +/- 8.07 ml.kg-1.day-1. Average CO2 production was 0.85 +/- 0.20 ml.g-1.h-1, which corresponds to a field metabolic rate of 0.55 +/- 0.13 MJ.kg-1...
  19. pmc Vascular actions of purines in the foetal circulation of the human placenta
    M A Read
    Department of Obstetrics and Gynaecology, John Hunter Hospital, NSW, Australia
    Br J Pharmacol 110:454-60. 1993
    ..placenta were bilaterally perfused in vitro with Krebs buffer (maternal and foetal sides 5 ml min-1 each, 95% O2:5% CO2, 37 degrees C)...
  20. pmc Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide
    C Jiang
    Department of Cardiac Medicine, University of London
    Br J Pharmacol 111:711-6. 1994
    ..glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial ..
  21. ncbi [Effects of nicorandil, a potassium agonist, on the human umbilical artery. Role of the vascular endothelium]
    A Tiritilli
    Laboratoire de Physiologie et Pharmacologie Cardiovasculaire, , Saint-Gerrmainen-Laye
    Arch Mal Coeur Vaiss 88:1095-9. 1995
    ..Rings of human umbilical artery 3 mm wide were placed in glycosated, oxygenated (95% O2, 5% CO2) Krebs-Henseleit solution, at 37 degrees C, pH 7.4 for isometric myography...
  22. ncbi [Studies on the influence of releasing hormones TRH and CRH on respiratory regulation]
    M Nink
    III. Medizinische Klinik und Poliklinik, Innere Medizin,
    Pneumologie 45:246-8. 1991
    ..persists also during hypercapnia, as we showed in patients and in 12 healthy test subjects while re-breathing CO2: when compared to placebo, CRH i.v. (200 micrograms...
  23. ncbi The effects of endogenous or exogenous catecholamines on blood respiratory status during acute hypoxia in rainbow trout (Oncorhynchus mykiss)
    S F Perry
    Laboratoire de Physiologie Animale, , Brest, France
    J Comp Physiol B 161:489-97. 1991
    ..on blood respiratory/acid-base status, and to provide in vivo evidence for adrenergic retention of carbon dioxide (CO2) in fish blood (cf. Wood and Perry 1985)...
  24. ncbi The electrogenic Na/HCO3 cotransporter
    W F Boron
    Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA
    Wien Klin Wochenschr 109:445-56. 1997
    ..Our expression assay was to apply 1.5% CO2/10 mM HCO3- (pH 7.5), allow pHi to stabilize from the CO2-induced acidification, and then remove bath Na+...
  25. ncbi Capacity of enzymes of the euphorbiacea Aleurites montana involved in CO2-fixation, compared to plants having C3-, C4- and Crassulacean acid metabolism
    N Grotjohann
    , , , Bundesrepublik Deutschland
    Z Naturforsch C 55:383-91. 2000
    ..ME) and of malate dehydrogenase (MDH) were measured in the Euphorbiacea Aleurites montana, grown under 700 ppm CO2 for four weeks prior to enzyme extraction. For comparison Bryophyllum daigremontiana (CAM)...
  26. ncbi The kinetics of hydroxyl-radical-induced strand breakage of hyaluronic acid. A pulse radiolysis study using conductometry and laser-light-scattering
    D J Deeble
    , Bundesrepublik Deutschland
    Z Naturforsch C 45:1031-43. 1990
    ..g. at pH 7 G(strand breaks) = 0.7 x 10(-7) mol J-1 and at pH 10.4, 4.8 x 10(-7) mol J-7. The radiolytic yields of CO2, H2O2, organic hydroperoxides, O2...
  27. ncbi [Toluene diisocyanate-induced bronchial hyperreactivity in an animal model of occupationally-induced lung diseases]
    W Marek
    ,
    Pneumologie 47:215-22. 1993
    ..of inspiratory pressure generation (dPoes/TI), arterial pressure (Pa) or arterial blood-gas tensions (PaO2, Pa-CO2) within time of exposure...
  28. ncbi Effects of PTH(1-34) on blood pressure, renal function, and hormones in essential hypertension: the altered pattern of reactivity may counteract raised blood pressure
    B Jespersen
    Department of Medicine and Nephrology B, Herlev Hospital, University of Copenhagen, Denmark
    Am J Hypertens 10:1356-67. 1997
    ..The pulse rate rose to a similar extent in the two groups, but cardiac output, measured by the CO2 rebreathing technique, was unchanged...
  29. pmc Activation of rabbit platelets by Ca2+ influx and thromboxane A2 release in an external Ca(2+)-dependent manner by zooxanthellatoxin-A, a novel polyol
    M C Rho
    Department of Pharmaceutical Molecular Biology, Faculty of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
    Br J Pharmacol 115:433-40. 1995
    ..2. ZT-A did not cause platelet aggregation or increase [Ca2+]i in a Ca(2+)-free solution, and Cd2+ (0.1-1 mM), Co2+ (1-10 mM) and Mn2+ (1-10 mM) inhibited ZT-A-induced aggregation...
  30. ncbi On the role of Ca2(+)-calmodulin-dependent and cAMP-dependent protein phosphorylation in the circadian rhythm of Neurospora crassa
    D Techel
    Department of Biology, University of Bremen, Federal Republic of Germany
    J Comp Physiol B 159:695-706. 1990
    Pulses of some Ca2+ channel blockers (dantrolene, Co2+, nifedipine) and calmodulin inhibitors (chlorpromazine) lead to medium (maximally 5-9 h) phase shifts of the circadian conidiation rhythm of Neurospora crassa...
  31. ncbi Resting distribution and stimulated translocation of protein kinase C isoforms alpha, epsilon and zeta in response to bradykinin and TNF in human endothelial cells
    D Ross
    Department of Physiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614, USA
    Endothelium 5:321-32. 1997
    ..HUVEC were incubated at 37 degrees C and 5% CO2 for 1 min, 15 min and 3 h with either bradykinin (1 microM) or TNF (100 U/ml)...
  32. ncbi [Postnatal development of breathing control]
    T Schafer
    Abteilung fur angewandte Physiologie, Ruhr Universitat Bochum
    Pneumologie 51:411-4. 1997
    ..The thresholds of the chemosensitive systems adapt during the first hours and days of life (CO2 sensitivity) or weeks (hypoxic sensitivity)...
  33. pmc Inhibition by opioids acting on mu-receptors of GABAergic and glutamatergic postsynaptic potentials in single rat periaqueductal gray neurones in vitro
    B Chieng
    Department of Pharmacology, University of Sydney, NSW, Australia
    Br J Pharmacol 113:303-9. 1994
    ..and were abolished during superfusion with solutions containing tetrodoxotoxin (100 nM to 1 microM, n = 5) or Co2+ (4 mM, n = 2). 3...
  34. pmc The influence of endothelin-1 on human foeto-placental blood vessels: a comparison with 5-hydroxytryptamine
    M R MacLean
    Autonomic Physiology Unit, Institute of Physiology, Glasgow University
    Br J Pharmacol 106:937-41. 1992
    ..Arterial preparations were gassed with 2.5% O2, 8% CO2 balance N2 and venous preparations were gassed with 5% O2, 6% CO2 balance N2 to simulate the conditions prevalent ..
  35. ncbi Energy intake and utilisation by nursing bearded seal (Erignathus barbatus) pups from Svalbard, Norway
    C Lydersen
    Norwegian Polar Institute, , Norway
    J Comp Physiol B 166:405-11. 1996
    ..Average daily water influx for the pups was 69.5 +/- 9.0 ml.kg-1. day-1. Average CO2 production during the study period was 0.99 +/- 0.10 ml.g-1...
  36. ncbi Acute cardiovascular effect of 1,25-dihydroxycholecalciferol in essential hypertension
    B Jespersen
    Department of Medicine, Herlev Hospital, University of Copenhagen, Denmark
    Am J Hypertens 11:659-66. 1998
    ..hypertensive patients, a transient increase in blood pressure and a reciprocal fall in cardiac output measured by a CO2 rebreathing technique (-15%, P < .05) were observed after 1,25-D injection...
  37. pmc Differential role of two Ca(2+)-permeable non-NMDA glutamate channels in rat retinal ganglion cells: kainate-induced cytoplasmic and nuclear Ca2+ signals
    T Leinders-Zufall
    Department of Neurology, Yale University School of Medicine, West Haven, Connecticut
    J Neurophysiol 72:2503-16. 1994
    ..In addition, divalent-permeable non-NMDA receptor channels were studied in retinal slices using a Co2+ staining technique. 2. Using Ca2+ (2...
  38. pmc [Standardization of the Neisseria meningitidis antibiogram. Detection of strains relatively resistant to penicillin]
    P Nicolas
    , France
    Bull World Health Organ 76:393-400. 1998
    ..agar dilution (reference method), E-test and disc diffusion method on Mueller-Hinton agar at 37 degrees C with 5% CO2 enabled us to standardize the antibiograms...
  39. ncbi Similarity of PO2 and PCO2 values in the air cell of eggs of birds and in the alveolar gas of humans at sea level and at high altitude
    C Monge
    Department of Physiological Sciences, Instituto de Investigaciones de la Altura IIA, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Comp Physiol B 164:156-8. 1994
    ..Air cell O2 (48.3 +/- 1.6 torr) and CO2 (20.9 +/- 0...
  40. ncbi Inhibition of acidification rate in cultured fibroblasts by glucocorticoids. Application of silicon microphysiometry to endocrinology
    D M Redish
    Department of Biological Sciences, Stanford University, California
    Horm Metab Res 25:264-7. 1993
    ..space of acidic metabolic products of glycolysis, respiration, and ATP hydrolysis, including lactic acid, CO2, and protons...
  41. ncbi [Haemophilus aphrophilus isolated from the blood of a patient with infective endocarditis]
    I Yoshioka
    Department of Medical Laboratory, Kansai Denryoku Hospital
    Kansenshogaku Zasshi 69:777-84. 1995
    ..Atmosphere with 5% CO2 failed to enhance their growth. All the five strains of H. aphrophilus isolated, required neither factors V nor X...
  42. ncbi The effects of exogenous extracellular carbonic anhydrase on CO2 excretion in rainbow trout (Oncorhynchus mykiss): role of plasma buffering capacity
    P R Desforges
    Department of Biology, University of Ottawa, Ontario, Canada
    J Comp Physiol B 171:465-73. 2001
    ..An injection of 5 mg kg(-1) carbonic anhydrase equally reduced (after 90 min) the arterial partial pressure of CO2 in trout with regular (-0.23+/-0.05 Torr) or high (-0.20+/-0...
  43. ncbi [Laser assisted uvulopalatoplasty (LAUP) in the treatment of snoring and obstructive sleep apnea syndrome]
    G Namysłowski
    Katedra i Oddział Kliniczny Laryngologii Slaskiej AM w Zabrzu
    Otolaryngol Pol 55:363-8. 2001
    ..by turbinate hypertrophy or septal deviation we performed septoplasty or partial inferior turbinectomy by laser CO2. In some cases with palatin or lingual tonsils hypertrophy we also performed tonsillectomy or lingual tonsil laser ..
  44. ncbi [Cardiac adaptation to muscular exercise in children after complete repair of tetralogy of Fallot]
    S Guillaumont
    , CHU Arnaud-de-Villeneuve, Montpellier
    Arch Mal Coeur Vaiss 89:587-92. 1996
    ..stress test with incremental load on a bicycle ergometer was carried out with measurement of the cardiac output by CO2 rebreathing (experimental method)...
  45. ncbi Properties of a protein from Staphylococcus capitis that binds human serum high density lipoprotein
    A Osland
    Department of Microbiology and Immunology, Gade Institute, University of Bergen, Norway
    Zentralbl Bakteriol Mikrobiol Hyg A 268:435-47. 1988
    ..Growth of the bacteria on medium containing cysteine or in presence of CO2, was found to induce the synthesis of this factor...
  46. ncbi Comparison between the growth of Yersinia enterocolitica, listeria monocytogenes, escherichia coli O157:H7 and salmonella spp. in ground beef packed by three commercially used packaging techniques
    H Nissen
    MATFORSK, Norwegian Food Research Institute, Oslovn
    Int J Food Microbiol 59:211-20. 2000
    ..coli O157:H7 and strains of Salmonella were compared in ground beef packed in modified atmospheres of 60% CO2/40% N2/0...
  47. ncbi [Acute disorder of ventilation-perfusion of the lung caused by inhalative smoking of 20 cigarettes]
    F W Rieben
    Medizinische Universitäts Klinik, Heidelberg
    Pneumologie 49:596-600. 1995
    ..025) by 1.0 (mmHg) in ergometric exercise (women 75 Watts, men 100 Watts) as well as of the partial pressure of CO2 (p < 0.05) by 0.9 (mmHg) at rest. At the same time, the alveolo-arterial CO2 difference increased (p < 0...
  48. ncbi Bicarbonate permeability and immunological evidence for an anion exchanger-like protein in the red blood cells of the sea lamprey, Petromyzon marinus
    B A Cameron
    Department of Biology, Queen s University, Kingston, Ontario, Canada
    J Comp Physiol B 166:197-204. 1996
    ..Results of the physiological experiments which measured CO2 production after adding H14CO3- to the extracellular saline, indicated significant transmembrane bicarbonate ..
  49. ncbi [Effect of surgical positioning and spinal anesthesia on lung function]
    B Rassler

    Pneumologie 55:31-7. 2001
    ..Under spinal anaesthesia, the arterial O2 saturation and the end-expiratory partial pressure of CO2 were measured additionally...
  50. ncbi UDP-glucose: flavonol 7-O-glucosyltransferase activity in flower extracts of Chrysanthemum segetum
    K Stich
    TU Wien, , Technische Mikroskopie und Organische Rohstofflehre, Vienna, Austria
    Z Naturforsch C 52:153-8. 1997
    ..Addition of Mg2+, Ca2+ and KCN slightly stimulated 7-O-glucosylation, whereas Co2+, Cu2+, Fe2+, Hg2+, p-hydroxymercuribenzoate and N-ethylmaleimide showed a strong inhibitory effect...
  51. ncbi On-line computer system to minimize laser injuries during surgery: preliminary system layout and proposal of the key features
    F Canestri
    Hewlett Packard Company GmbH, , Germany
    Proc Inst Mech Eng H 213:69-76. 1999
    ..According to surgeons operating with a variety of CO2 lasers available at both the National Cancer Institute in Milan, Italy, and the Sackler School of Medicine, Tel ..
  52. ncbi Activity, milk intake and energy consumption in free-living ringed seal (Phoca hispida) pups
    C Lydersen
    University of Oslo, Department of Biology, Norway
    J Comp Physiol B 163:433-8. 1993
    ..The total water flux was measured to be 52 +/- 10 ml.kg-1.day-1. Average CO2 production was 0.85 +/- 0.16 ml.g-1.h-1, corresponding to a field metabolic rate of 0.55 +/- 0.10 MJ.kg-1...
  53. ncbi [Infectious endocarditis induced by Actinobacillus actinomycetemcomitans. 8 new cases]
    A Grand
    Service de cardiologie, Centre Hospitalier de Valence
    Arch Mal Coeur Vaiss 87:1721-9. 1994
    ..The diagnosis is confirmed on blood cultures but the organism grows slowly in CO2 enriched atmosphere...
  54. ncbi Pulmonary receptors in reptiles: discharge patterns of receptor populations in snakes versus turtles
    L Sundin
    Department of Zoology, University of British Columbia, Vancouver, Canada
    J Comp Physiol B 171:103-11. 2001
    This study examines the effects of lung inflation/deflation with and without CO2 on the entire population of pulmonary receptors in the vagus nerve in two species of snakes and two species of turtles...
  55. ncbi [Measurement of the Fowler dead space in patients with pulmonary emphysema using C18O2]
    T Meyer
    GSF, ,
    Pneumologie 55:126-9. 2001
    ..1; expirogram 1). CO2 labeled with the stable oxygen isotope 18O (C18O2) is completely taken up in the gas exchanging region of the lung, ..
  56. ncbi Short-chain fatty acids and CO2 as regulators of Na+ and Cl- absorption in isolated sheep rumen mucosa
    G Gabel
    Institut für Veterinärphysiologie, Freie Universitat Berlin, Federal Republic of Germany
    J Comp Physiol B 161:419-26. 1991
    ..In both CO2/HCO3(-)-containing and CO2/HCO3(-)-free solutions, replacement of gluconate by short-chain fatty acids (SCFA, 39mM) ..
  57. ncbi [Efficiency of portable sleep apnea screening instruments]
    N Netzer
    Klinik Bad Reichenhall der LVA Niederbayern/Oberpfalz
    Pneumologie 47:126-9. 1993
    ..by parallel measurements on 19 female and male patients and controlled the results obtained by measurements with a CO2 infrared absorption spectrometer in our sleep lab...
  58. ncbi [In vitro exposure of a human bronchial epithelial cell line with nitrogen dioxide induces enhanced transcription and liberation of pro-inflammatory cytokines]
    K Kienast

    Pneumologie 49:695-9. 1995
    ..5 ppm with the apical fluids removed with 5% CO2 at 37 degrees C. The cells were hydrated with Hanks' Balanced Salt Solution (HBSS) in the basolateral compartment...
  59. pmc Laparoscopic intestinal injury: a review and case presentation
    A Ostrzenski
    Institute of Gynecology and the Department of Gynecology and Obstetrics, University of South Florida, Tampa, USA
    J Natl Med Assoc 93:440-3. 2001
    ..Enough time elapsed from laparoscopic surgery for CO2 and irrigation-fluid absorption; therefore, additional studies were ordered (an abdominal upright x-ray was ..
  60. ncbi Respiratory gas exchange, nitrogenous waste excretion, and fuel usage during starvation in juvenile rainbow trout, Oncorhynchus mykiss
    R F Lauff
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    J Comp Physiol B 165:542-51. 1996
    Oxygen consumption, CO2 excretion, and nitrogenous waste excretion (75% ammonia-N and 25% urea-N) were measured daily in 4-g rainbow trout over a 15-day starvation period...
  61. ncbi Cerebral blood flow and CO2 reactivity in interictal migraineurs: a transcranial Doppler study
    A Kastrup
    Department of Neurology, , Germany
    Headache 38:608-13. 1998
    ..01). The broad overlap of cerebrovascular blood flow velocities and CO2 reactivities in patients and controls precluded identification of values diagnostic of migraine...
  62. ncbi Gas chromatographic kinetic study of carbon monoxide oxidation over platinum-rhodium alloy catalysts
    D Gavril
    Department of Chemistry, University of Patras, Greece
    J Chromatogr A 852:507-23. 1999
    ..All the catalysts show a maximum rate constant for the production of CO2 at a characteristic temperature close to that found in the literature...
  63. pmc Effect of the putative cognitive enhancer, linopirdine (DuP 996), on quantal parameters of acetylcholine release at the frog neuromuscular junction
    S D Provan
    Department of Pharmacology, James H Quillen College of Medicine, East Tennessee State University, Johnson City 37614 0577
    Br J Pharmacol 111:1103-10. 1994
    ..3. Block of presynaptic Na(+)- and Ca(2+)-channels with 3 microM tetrodoxin and 1.8 mM Co2+ prevented the m.e.p.p. frequency increase to DuP996, and this effect was completely reversed by washing. 4...
  64. ncbi Energetics during nursing and early postweaning fasting in hooded seal (Cystophora cristata) pups from the Gulf of St Lawrence, Canada
    C Lydersen
    Norwegian Polar Institute, , Norway
    J Comp Physiol B 167:81-8. 1997
    ..During the nursing period the average daily water influx for the pups was 124.6 +/- 25.8 ml.kg-1. The average CO2 .production during this period was 1.10 +/- 0.20 ml.g-1...
  65. ncbi [Inducibility of tumor necrosis factor alpha to peritoneal macrophages and lethality to mice of clinical isolates of Staphylococcus aureus]
    N Endo
    Department of Immunology, Kyorin University School of Health Sciences
    Kansenshogaku Zasshi 72:231-7. 1998
    ..aureus (21 strains)(S. aureus-CS) for 4 hrs at 37 degrees C in a 5% CO2-air humidified incubator, TNF alpha induction from the treated cells was observed in 20/21 strains...
  66. ncbi Chronic cluster headache: provocation with carbon dioxide breathing and nitroglycerin
    J Hannerz
    Department of Neurology, Karolinska Hospital, Stockholm, Sweden
    Headache 36:174-7. 1996
    ..artery blood flow, vascular resistance, and intensity and duration of pain before, during, and after breathing 6% CO2 in air for 6 minutes and before and after administration of 1 mg nitroglycerin sublingually...
  67. ncbi Active calcium ion transport Xenopus laevis skin
    S M Guirguis
    Biological Sciences Department, California State Polytechnic University, Pomona 91768, USA
    J Comp Physiol B 167:328-34. 1997
    ..l-1; Ni2+ was also effective at 500 mumol.l-1 but Co2+ was ineffective up to 500 mumol.l-1...
  68. doi Chapter 1. Impacts of the oceans on climate change
    Philip C Reid
    Sir Alister Hardy Foundation for Ocean Science, The Laboratory, Citadel Hill, Plymouth PL1 2PB, United Kingdom
    Adv Mar Biol 56:1-150. 2009
    ..The oceans are also the main store of carbon dioxide (CO2), and are estimated to have taken up approximately 40% of anthropogenic-sourced CO2 from the atmosphere since the ..
  69. ncbi Mitigation of global greenhouse gas emissions from waste: conclusions and strategies from the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report. Working Group III (Mitigation)
    Jean Bogner
    Landfills, Inc, Wheaton, Illinois 60187, USA
    Waste Manag Res 26:11-32. 2008
    ..Emissions for 2004-2005 totalled 1.4 Gt CO2-eq year(-1) relative to total emissions from all sectors of 49 Gt CO2-eq year(-1) [including carbon dioxide (CO2), ..
  70. ncbi Ventilation time of the middle ear in otitis media with effusion (OME) after CO2 laser myringotomy
    Benedikt Sedlmaier
    Ear, Nose and Throat Department, Medical Center Benjamin Franklin, Free University of Berlin, Germany
    Laryngoscope 112:661-8. 2002
    ..ventilation time, the healing course of the tympanic membrane, the early and late complications, and the recurrence rate of otitis media with effusion (OME) within 6 months after CO2 laser myringotomy with the CO2 laser otoscope Otoscan.
  71. ncbi Effects of elevated carbon dioxide concentration on growth and nitrogen fixation in Alnus glutinosa in a long-term field experiment
    V M Temperton
    Institute of Ecology and Resource Management, University of Edinburgh, Darwin Building, King s Buildings, Mayfield Road, Edinburgh EH9 3JU, UK
    Tree Physiol 23:1051-9. 2003
    Nitrogen-fixing plant species may respond more positively to elevated atmospheric carbon dioxide concentrations ([CO2]) than other species because of their ability to maintain a high internal nutrient supply...
  72. doi Effect of modified atmosphere and temperature abuse on the growth from spores and cereulide production of Bacillus weihenstephanensis in a cooked chilled meat sausage
    Line Thorsen
    Department of Food Science, Faculty of Life Science, Copenhagen University, Frederiksberg C, Denmark
    Int J Food Microbiol 130:172-8. 2009
    ..weihenstephanensis is sensitive to MAP containing CO2. The sensitivity to 20% CO2 was dependent on strain and oxygen level, being increased when oxygen was excluded from ..
  73. ncbi CO2/H(+) sensing: peripheral and central chemoreception
    Sukhamay Lahiri
    Department of Physiology, University of Pennsylvania Medical Center, Richards Building, Philadelphia, PA 19104, USA
    Int J Biochem Cell Biol 35:1413-35. 2003
    ..But CO2 relates to ventilation and H(+) to kidney. Hence, the title of the chapter...
  74. ncbi Kinetic and mutational studies of the number of interacting divalent cations required by bacterial and human methionine aminopeptidases
    Xiaoyi V Hu
    Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Biochemistry 46:12833-43. 2007
    ..the mitochondrial targeting sequence (residues 1-55) have been characterized as metal-requiring proteases, with Co2+ being the best activator. At the optimal pH (8.0), the kcat of MetAP1D of 0...
  75. ncbi Low CO2 stimulates inositol phosphate turnover and increased inositol 1,4,5-trisphosphate levels in piglet cerebral microvascular smooth muscle cells
    M L Albuquerque
    Department of Physiology and Biophysics, University of Tennessee, Memphis 38163, USA
    Proc Soc Exp Biol Med 209:14-9. 1995
    ..The hypothesis that increased pH or decreased CO2 tension increases inositol phosphate turnover in piglet cerebral microvascular smooth muscle (SM) cells was ..
  76. doi Effect of packaging atmosphere on the microbial attributes of pearlspot (Etroplus suratensis Bloch) stored at 0-2 degrees C
    C N Ravi Sankar
    Central Institute of Fisheries Technology, Cochin 682 029, India
    Food Microbiol 25:518-28. 2008
    Effect of packaging atmosphere (air and under different modified atmospheres (MAs), 40% CO2/60% O2, 50%/50% O2, 60% CO2/40% O2, 70% CO2/30% O2 and 40% CO2/30% O2/30% N2) on the microbial and biochemical attributes of fresh pearlspot (..
  77. pmc Seasonal variation in CO2 efflux of stems and branches of Norway spruce trees
    Manuel Acosta
    Laboratory of Plants Ecological Physiology, Institute of Systems Biology and Ecology, Academy of Sciences of the Czech Republic, Porici 3b, 603 00 Brno, The Czech Republic
    Ann Bot 101:469-77. 2008
    ..from May to October in four consecutive years in order (1) to evaluate the influence of temperature on woody tissue CO2 efflux with special focus on variation in Q10 (change in respiration rate resulting from a 10 degrees C increase in ..
  78. doi [Air quality in schools - classroom levels of carbon dioxide (CO2), volatile organic compounds (VOC), aldehydes, endotoxins and cat allergen]
    H Fromme
    Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Sachgebiet Umweltmedizin, Oberschleissheim
    Gesundheitswesen 70:88-97. 2008
    ..Indoor air climate parameters (temperature, relative humidity), carbon dioxide (CO2) and various volatile organic compounds, aldehydes and ketones were measured...
  79. ncbi Photodynamic therapy for premalignant lesions in DMBA-treated hamsters: a preliminary study
    J S Kingsbury
    Department of Oral and Maxillofacial Surgery, State University of New York at Buffalo, School of Dental Medicine 14214, USA
    J Oral Maxillofac Surg 55:376-81; discussion 381-2. 1997
    ..The aim of this investigation was to determine if this premalignant tissue could be selectively destroyed by systemically administered Photofrin activated by 630 nm red light via an argon dye laser...
  80. ncbi Control of carbon partitioning and photosynthesis by the triose phosphate/phosphate translocator in transgenic tobacco plants (Nicotiana tabacum). II. Assessment of control coefficients of the triose phosphate/phosphate translocator
    R E Häusler
    Botanisches Institut der Universitat zu Koln, Germany
    Planta 210:383-90. 2000
    ..TPT) were used to study the control the TPT exerts on the flux of starch and sucrose biosynthesis, as well as CO2 assimilation, respiration and photosynthetic electron transport...
  81. ncbi The combined affects of modified atmosphere, temperature, nisin and ALTA 2341 on the growth of Listeria monocytogenes
    E A Szabo
    Food Science Australia, North Ryde Laboratory, Sydney
    Int J Food Microbiol 43:21-31. 1998
    ..activity of the bacteriocins nisin and ALTA 2341 in combination with various atmospheres: air, 100% N2, 40% CO2:60% N2, or 100% CO2. Buffered tryptone soya broth (pH 6...
  82. ncbi Diameter growth of Scots pine (Pinus sylvestris) trees grown at elevated temperature and carbon dioxide concentration under boreal conditions
    Heli Peltola
    University of Joensuu, Faculty of Forestry, FIN 80101 Joensuu, Finland
    Tree Physiol 22:963-72. 2002
    We investigated the impacts of elevated temperature and carbon dioxide concentration ([CO2]) on diameter growth of Scots pine (Pinus sylvestris L...
  83. ncbi Effects of an experimentally developed adhesive resin system and CO2 laser irradiation on direct pulp capping
    Masaya Suzuki
    Advanced Operative Dentistry Endodontics, Graduate School of Dentistry at Niigata, The Nippon Dental University, Japan
    Oper Dent 30:702-18. 2005
    ..process of rat pulp directly capped with various experimentally developed adhesive resin systems and treated with CO2 laser irradiation. The experimental adhesive resins used in this study were made from Clearfil Mega Bond (MB)...
  84. ncbi Collagen tightening induced by carbon dioxide laser versus erbium: YAG laser
    R E Fitzpatrick
    Department of Medicine, University of California at San Diego, USA
    Lasers Surg Med 27:395-403. 2000
    Pulsed CO2 laser resurfacing improves photodamage and acne scarring by ablation of abnormal tissue with subsequent regeneration and remodeling of collagen and through heat induced collagen contraction...
  85. pmc CO2 assimilation, ribulose-1,5-bisphosphate carboxylase/oxygenase, carbohydrates and photosynthetic electron transport probed by the JIP-test, of tea leaves in response to phosphorus supply
    Zheng He Lin
    Institute of Horticultural Plant Physiology, Biochemistry and Molecular Biology, Fujian Agriculture and Forestry University, Fuzhou, 350002, PR China
    BMC Plant Biol 9:43. 2009
    ..This objective of this study was to determine how P deficiency affects CO2 assimilation, Rubisco, carbohydrates and photosynthetic electron transport in tea leaves to understand the ..
  86. ncbi Field sampling of the tick Amblyomma variegatum (Acari: Ixodidae) on pastures in Guadeloupe; attraction of CO2 and/or tick pheromones and conditions of use
    N Barre
    CIRAD EMVT, Pointe à Pitre Guadeloupe, FWI, France
    Exp Appl Acarol 21:95-108. 1997
    ..b>CO2 was absolutely necessary to activate ticks, including the larvae...
  87. ncbi Maintenance of subcutaneous cavities with CO2
    Martin Iglesias
    Plastic Surgery Service, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico DF, Mexico
    Ann Plast Surg 57:418-21. 2006
    ..in endoscopic plastic surgery cause certain drawbacks, we developed a model in dogs, which, by insufflating CO2 into a subcutaneous cavity, we were able to maintain...
  88. ncbi Spatial and temporal performance of the miniface (free air CO2 enrichment) system on Bog Ecosystems in northern and Central Europe
    F Miglietta
    IATA-CNR, Institute of Agrometeorology and Environmental Analysis, National Research Council, P. le delle Cascine 18, 50144 Firenze, Italy
    Environ Monit Assess 66:107-27. 2001
    ..project was initiated to investigate, at five climatically different sites across Europe, the effects of elevated CO2 and N deposition on the net exchange of CO2 and CH4 between bogs and the atmosphere, and to study the effects of ..
  89. pmc Elevated atmospheric CO2 and strain of rhizobium alter freezing tolerance and cold-induced molecular changes in alfalfa (Medicago sativa)
    Annick Bertrand
    Agriculture and Agri Food Canada, 2560, Soils and Crops Research and Development Centre, 2560 Hochelaga Boulevard, Quebec, Quebec, G1V 2J3, Canada
    Ann Bot 99:275-84. 2007
    The objective of the study was to assess the impact of elevated CO2 in interaction with rhizobial strains on freezing tolerance and cold-induced molecular changes in alfalfa.
  90. doi Microdrill, CO2-laser, and piezoelectric stapedotomy: a comparative study
    Domenico Cuda
    Department of Otolaryngology, Guglielmo da Saliceto Hospital, Piacenza, Italy
    Otol Neurotol 30:1111-5. 2009
    ..To compare 3 different devices used to perforate the stapes footplate in otosclerotic patients...
  91. ncbi Successful pig embryonic development in vitro outside a CO2 gas-regulated incubator: effects of pH and osmolality
    Manabu Ozawa
    Genetic Diversity Department, National Institute of Agrobiological Sciences, Kannondai 2 1 2, Tsukuba, Ibaraki 305 8602, Japan
    Theriogenology 65:860-9. 2006
    ..the developmental ability of porcine embryos produced in vitro using tightly closed glass tubes in the absence of a CO2 gas-regulated incubator...
  92. ncbi Effects of carbon dioxide inhalation on hematology, coagulation, and serum clinical chemistry values in rats
    G L Walter
    MPI Research, Mattawan, Michigan, USA
    Toxicol Pathol 27:217-25. 1999
    ..at weekly intervals for 4 wk to evaluate the effects of inhalation of an anesthetic dose of carbon dioxide (CO2) or of a carbon dioxide-oxygen mixture (CO2/O2) on hematology, coagulation, and serum biochemistry values...
  93. ncbi Peritoneal, systemic, and distant organ inflammatory responses are reduced by a laparoscopic approach and carbon dioxide versus air
    B M Ure
    Department of Pediatric Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Surg Endosc 16:836-42. 2002
    ..surgery have, among other factors, been attributed to a shorter length of abdominal incision and the use of CO2 versus air. An analysis of these factors taking pressure-induced alterations into account is lacking...
  94. ncbi A randomized controlled study evaluating the effects of the temperature of insufflated CO2 on core body temperature and blood gases (an experimental study)
    E Bashirov
    Department of General Surgery, Mustafa Kemal University School of Medicine, Bagriyanik Mah, 31100, Antakya, Hatay, Turkey
    Surg Endosc 21:1820-5. 2007
    Heated carbon dioxide (CO2) was used for pneumoperitoneum (Pp) to prevent hypothermia...
  95. ncbi Leaf respiration at different canopy positions in sweetgum (Liquidambar styraciflua) grown in ambient and elevated concentrations of carbon dioxide in the field
    David T Tissue
    Department of Biology, Texas Tech University, Lubbock, TX 79409 3131, USA
    Tree Physiol 22:1157-66. 2002
    Trees exposed to elevated CO2 partial pressure ([CO2]) generally show increased rates of photosynthesis and growth, but effects on leaf respiration are more variable. The causes of this variable response are unresolved...
  96. pmc Increased propensity for central apnea in patients with obstructive sleep apnea: effect of nasal continuous positive airway pressure
    Anan Salloum
    Wayne State University School of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Harper University Hospital, 3 Hudson 3990 John R, Detroit, MI 48201, USA
    Am J Respir Crit Care Med 181:189-93. 2010
    ..There is increasing evidence of increased ventilatory instability in patients with obstructive sleep apnea (OSA), but previous investigations have not studied whether the hypocapnic apneic threshold is altered in this group...
  97. ncbi Separation and capture of CO2 from large stationary sources and sequestration in geological formations--coalbeds and deep saline aquifers
    Curt M White
    DOE, National Energy Technology Laboratory, Pittsburgh, Pennsylvania 15236, USA
    J Air Waste Manag Assoc 53:645-715. 2003
    The topic of global warming as a result of increased atmospheric CO2 concentration is arguably the most important environmental issue that the world faces today. It is a global problem that will need to be solved on a global level...
  98. ncbi Histopathologic and morphometric evaluation of the skin abnormalities induced by erbium:YAG and carbon dioxide lasers in 10 patients
    L de Noronha
    Division of Plastic Surgery, Hospital Nossa Senhora das Gracas, Laboratory of Experimental Pathology, Curitiba, Brazil
    Plast Reconstr Surg 108:1380-8. 2001
    In the 1960s, carbon dioxide (CO2) laser therapy started to be applied to eliminate wrinkles, actinic scars, and acne because of its capacity of induce intracellular water vaporization...
  99. doi Stem juice production of the C4 sugarcane (Saccharum officinarum) is enhanced by growth at double-ambient CO2 and high temperature
    Joseph C V Vu
    United States Department of Agriculture Agricultural Research Service, Center for Medical, Agricultural and Veterinary Entomology, Chemistry Research Unit, 1600 1700 SW 23rd Drive, Gainesville, FL 32608 1069, USA
    J Plant Physiol 166:1141-51. 2009
    ..and CP88-1508) were grown for 3 months in paired-companion, temperature-gradient, sunlit greenhouses under daytime [CO2] of 360 (ambient) and 720 (double ambient) micromol mol(-1) and at temperatures of 1...
  100. pmc Effects of manganese-excess on CO2 assimilation, ribulose-1,5-bisphosphate carboxylase/oxygenase, carbohydrates and photosynthetic electron transport of leaves, and antioxidant systems of leaves and roots in Citrus grandis seedlings
    Qing Li
    Institute of Horticultural Plant Physiology, Biochemistry and Molecular Biology, Fujian Agriculture and Forestry University, Fuzhou, China
    BMC Plant Biol 10:42. 2010
    ..The objective of this study were to understand the mechanisms by which Mn-excess leads to a decrease in CO2 assimilation and to test the hypothesis that Mn-induced changes in antioxidant systems differ between roots and ..
  101. ncbi Influence of elevated CO2 and mycorrhizae on nitrogen acquisition: contrasting responses in Pinus taeda and Liquidambar styraciflua
    J V Constable
    Department of Biological Sciences, University of Illinois at Chicago, 60607, USA
    Tree Physiol 21:83-91. 2001
    ..system capacity to acquire nitrogen (N) is critical in assessing the long-term growth impact of rising atmospheric CO2 concentration ([CO2]) on trees and forest ecosystems...

Research Grants96

  1. LUNG DRUG DELIVERY WITH CARBON DIOXIDE AEROSOL INHALERS
    Brian Hansen; Fiscal Year: 2007
    ..Aerophase has developed an inexpensive carbon dioxide (CO2) propellant MDI that is competitive with the HFA MDIs, with high drug delivery efficiency and dose reproducibility...
  2. Disruption of Host-Seeking Behavior in Aedes and Culex Mosquitoes using Odorants
    Anandasankar Ray; Fiscal Year: 2010
    ..To achieve these goals we will focus on functional analyses of the CO2 sensing neuron...
  3. SURGICAL STUDIES OF SEVERE RESPIRATORY FAILURE
    Joseph Zwischenberger; Fiscal Year: 2004
    ..gas exchanger in a simple percutaneous arteriovenous shunt achieves near-total extracorporeal removal of CO2 production with only 800-1200 mL/min flow...
  4. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..A three-year BRP effort is proposed: Year 1 will confirm whether, and under what conditions, dense phase CO2 is an effective medium for sterilizing and cleaning common biomaterials and will focus on simple solid metallic, ..
  5. Utilizing Ethyl Nitrate Gas in Laparoscopic Surgery
    James Reynolds; Fiscal Year: 2006
    ..In addition, due to its plasma solubility, insufflation with CO2 will increase pCOz and decrease blood pH, actions that can produce respiratory acidosis, tachycardia, and ..
  6. A Transcutaneous Gas Sensor for Noninvasive Diagnosis of Necrotizing Enterocoliti
    OOMMAN VARGHESE; Fiscal Year: 2007
    ..In Phase II, we will develop a hydrogen and carbon dioxide (H2-CO2) sensor array for simultaneously detecting transcutaneous H2 and CO2 levels...
  7. Developmental defects in serotonin neurons and the response to O2 and CO2
    George B Richerson; Fiscal Year: 2010
    ..that respond to hypercapnia by inducing arousal, an increase in breathing, and other changes aimed at restoring pH/CO2 homeostasis...
  8. Developmental defects in serotonin neurons and the response to O2 and CO2
    George Richerson; Fiscal Year: 2007
    ..that respond to hypercapnia by inducing arousal, an increase in breathing, and other changes aimed at restoring pH/CO2 homeostasis...
  9. Multiscale Model of Neural Control of Breathing
    ILYA A contact RYBAK; Fiscal Year: 2010
    Respiration in mammals is a primal homeostatic process, regulating levels of oxygen (O2) and carbon dioxide (CO2) in blood and tissues and is crucial for life...
  10. TRAIT MARKER FOR PANIC DISORDER
    William Coryell; Fiscal Year: 2001
    ..The project also seeks to refine the definitions and thresholds used to identify meaningful hypersensitivity to CO2 and to explore relationships between such hypersensitivity and morbid childhood separation anxiety...
  11. Developmental defects in serotonin neurons and the response to O2 and CO2
    George Richerson; Fiscal Year: 2009
    ..that respond to hypercapnia by inducing arousal, an increase in breathing, and other changes aimed at restoring pH/CO2 homeostasis...
  12. MRI Progression Markers of Cognitive Decline in the Elderly
    Henry Rusinek; Fiscal Year: 2010
    ..artifact free measures of cerebral blood flow (CBF) in the HIP and test the vasoreactivity to carbon dioxide (VR-CO2). Aim 1 is to evaluate among MCI patients, CBF and VR-CO2 as predictors of cognitive decline...
  13. CATALYTIC MECHANISM OF CARBONIC ANHYDRASE
    David Silverman; Fiscal Year: 2007
    The reaction of physiological significance catalyzed by carbonic anhydrase (CA) is the hydration of carbon dioxide: CO2 + H20 -> <-HCO3- + H+...
  14. Genes and Neural Circuits Mediating Avoidance Behavior
    GREG S SUH; Fiscal Year: 2010
    ..Carbon dioxide (CO2), in contrast, elicits avoidance over a wide range of concentrations in the fly, Drosophila melanogaster, and ..
  15. CATALYTIC MECHANISM OF CARBONIC ANHYDRASE
    David Silverman; Fiscal Year: 1999
    The reaction of physiological significance catalyzed by the carbonic anhydrases is the hydration of carbon dioxide: CO2 + H2O yields or reversible action HCO3 + H+...
  16. Ambulatory Arteriovenous Carbon Dioxide Removal
    Joseph Zwischenberger; Fiscal Year: 2005
    ..gas exchanger in a simple percutaneous arteriovenous shunt to achieve near-total extracorporeal removal of CO2 production with only 800-1000 ml/min blood flow...
  17. Arterial Cannula with Permissive Distal Perfusion
    Kathryn Osterholzer; Fiscal Year: 2007
    ..AVCO2R is a respiratory treatment that uncouples oxygenation from CO2 removal by utilizing a low-resistance gas exchanger in a simple percutaneous arteriovenous shunt (i.e...
  18. CO2/H+ Modulation of Rhythmogenic Inspiratory Neurons
    SHEREE JOHNSON; Fiscal Year: 2007
    ..on a breath to breath basis ensure that breathing is commensurate with the oxygen supply and carbon dioxide (CO2) washout...
  19. PROKARYOTIC CARBONIC ANHYDRASE
    JAMES FERRY; Fiscal Year: 2000
    ..It facilitates in the liberation of CO stored in the form of HCO3- as in red cells and in the diffusion of CO2 across membranes...
  20. ROLE OF CALCINEURIN IN CRYPTOCOCCUS NEOFORMANS VIRULENCE
    Joseph Heitman; Fiscal Year: 2002
    ..strains are viable but sensitive to conditions in the infected host: elevated temperature, alkaline pH and 5% CO2. As a consequence, strains lacking calcineurin are nonpathogenic in animals...
  21. Terminal Sterilization of Tendon Allografts Using Supercritical CO2- Phase II
    Renee Christopher; Fiscal Year: 2007
    ..result of Phase 1 funding has been the development of a terminal sterilization technology using supercritical CO2 and a proprietary additive that will allow tissue banks to easily process soft tissue allografts to a sterility ..
  22. Heat Stress and Circulatory Control
    Craig G Crandall; Fiscal Year: 2010
    ..in: central blood volume, control of left ventricular end-diastolic volume, Frank-Starling relationship, arterial CO2 modulation of cerebral perfusion, and cerebrovascular autoregulation...
  23. CHEMICAL MECHANISMS OF BIOSYNTHESIS
    Richard Wolfenden; Fiscal Year: 2009
    ..molecule in its inhibitory complex with ODCase, in a gap deep in the active site that is believed to be occupied by CO2 released during decarboxylation...
  24. Targeting CO2 levels in breathing training for asthma
    THOMAS EKKEHARD contact RITZ; Fiscal Year: 2010
    ..Patients will participate in a four-week intervention with five training sessions and breathing home exercises, which is expected to improve their asthma control and well-being. ..
  25. CHEMICAL MECHANISMS OF BIOSYNTHESIS
    RICHARD VANCE WOLFENDEN; Fiscal Year: 2010
    ..molecule in its inhibitory complex with ODCase, in a gap deep in the active site that is believed to be occupied by CO2 released during decarboxylation...
  26. Targeting CO2 levels in breathing training for asthma
    Thomas Ritz; Fiscal Year: 2009
    ..Patients will participate in a four-week intervention with five training sessions and breathing home exercises, which is expected to improve their asthma control and well-being. ..
  27. CONTROL OF BREATHING DURING PHYSIOLOGIC CONDITIONS
    HUBERT FORSTER; Fiscal Year: 2004
    ..Major hypotheses are: 1) focal acidosis (equivalent to that breathing 7 percent inspired CO2, delta brain pH approximately -...
  28. MECHANISM(S) OF HYPERPNEA ELICITED BY CO2 INHALATION
    HUBERT FORSTER; Fiscal Year: 1980
    ..regarding the role of pulmonary, aortic, carotid and intracranial chemoreceptors in the hyperpnea elicited by CO2 inhalation...
  29. Signal Transduction in Intrapulmonary Chemoreceptors
    STEVEN HEMPLEMAN; Fiscal Year: 2007
    b>CO2-sensing respiratory chemoreceptors are found in diverse locations in air-breathing vertebrates, including multiple sites within the brainstem, carotid and aortic bodies, and lungs, affirming their functional importance in ..
  30. Molecular mechanisms of central chemoreception in breathing
    Marco Martina; Fiscal Year: 2010
    Chemoreceptors sensitive to the levels of CO2 or pH in the central nervous system are critical to the regulation of cardiorespiratory homeostasis...