Gene Symbol: C14orf177
Description: chromosome 14 open reading frame 177
Yang Q, Kathiresan S, Lin J, Tofler G, O Donnell C. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. BMC Med Genet. 2007;8 Suppl 1:S12 pubmed
..Further study of additional strongly associated SNPs and linked regions may identify novel variants that influence the inter-individual variability in hemostatic factors and hematological phenotypes. ..
Chu A, Guilianini F, Grallert H, Dupuis J, Ballantyne C, Barratt B, et al
. Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. Circ Cardiovasc Genet. 2012;5:676-85 pubmed publisher
..In addition, genome-wide significant associations with rosuvastatin-induced change in Lp-PLA(2) activity were observed in ABCG2 and LPA, likely because of their impact on statin-induced low-density lipoprotein cholesterol lowering. ..
Kunkle B, Jaworski J, Barral S, Vardarajan B, Beecham G, Martin E, et al
. Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease. Alzheimers Dement. 2016;12:2-10 pubmed publisher
..2 (LOD* = 4.18). The 1-LOD confidence interval for this region contains one gene, C14orf177, and the microRNA Mir_320, whereas IBD analyses implicates an additional gene BCL11B, a regulator of brain-..