B4GALNT2

Summary

Gene Symbol: B4GALNT2
Description: beta-1,4-N-acetyl-galactosaminyltransferase 2
Alias: B4GALT, GALGT2, beta-1,4 N-acetylgalactosaminyltransferase 2, UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase, UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase, beta 1,4 N-acetylgalactosaminyltransferase/betal,4 GalNAcT/Sda-GalNAcT, beta-1,4-N-acetyl-galactosaminyl transferase 2, beta-4-N-acetylgalactosaminyltransferase, sd(a) beta-1,4-GalNAc transferase, sda beta-1,4-GalNAc transferase
Species: human
Products:     B4GALNT2

Top Publications

  1. Li Y, Ueng K, Jeng J, Charng M, Lin T, Chien K, et al. 2017 Taiwan lipid guidelines for high risk patients. J Formos Med Assoc. 2017;116:217-248 pubmed publisher
    ..The major purpose is to improve clinical outcomes of these high risk patients through the control of hyperlipidemia. ..
  2. Parkan Õ, Atalay M, Koc A, Pala C, Aydemir G, Kaynar L. [Fungemia and septic arthritis caused by Saprochaete capitata in a patient with fanconi aplastic anemia: a case report]. Mikrobiyol Bul. 2017;51:87-93 pubmed
    ..In conclusion, S.capitata infections should be taken into consideration in the presence of fungemia and septic arthritis in hematological patients who receive caspofungin therapy. ..
  3. Schmidt S, Moncada M, Burger S, Geyer J. Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes. BMC Neurosci. 2015;16:35 pubmed publisher
  4. Raj R, Bhatti J, Badada S, Ramteke P. Genetic basis of dyslipidemia in disease precipitation of coronary artery disease (CAD) associated type 2 diabetes mellitus (T2DM). Diabetes Metab Res Rev. 2015;31:663-71 pubmed publisher
  5. Chipkin S, Klugh S, Chasan Taber L. Exercise and diabetes. Cardiol Clin. 2001;19:489-505 pubmed
    ..Identifying and preventing potential problems beforehand can reduce adverse outcomes and promote this important approach to healthy living...
  6. Hadj Ahmed S, Kharroubi W, Kaoubaa N, Zarrouk A, Batbout F, Gamra H, et al. Correlation of trans fatty acids with the severity of coronary artery disease lesions. Lipids Health Dis. 2018;17:52 pubmed publisher
    ..The measurement of these Trans FA would be of great value for the screening of lipid metabolism disorders in CAD patients. ..
  7. Van de Wiele C, Rimbu A, Belhocine T, De Spiegeleer B, Sathekge M, Maes A. Reversible myocardial perfusion defects in patients not suffering from obstructive epicardial coronary artery disease as assessed by coronary angiography. Q J Nucl Med Mol Imaging. 2018;62:325-335 pubmed publisher
    ..Finally, physical training in patients with primary microvascular angina appears to be associated with reduction of myocardial perfusion abnormalities. ..
  8. Sharma S, Jangale N, Harsulkar A, Gokhale M, Joshi B. Chronic maternal calcium and 25-hydroxyvitamin D deficiency in Wistar rats programs abnormal hepatic gene expression leading to hepatic steatosis in female offspring. J Nutr Biochem. 2017;43:36-46 pubmed publisher
  9. Tsai I, Wang C, Lu Y, Hung W, Wu C, Lu L, et al. The burden of major adverse cardiac events in patients with coronary artery disease. BMC Cardiovasc Disord. 2017;17:1 pubmed publisher
    ..Fortunately, these factors are modifiable and should be identified and monitored early. ..

More Information

Publications159 found, 100 shown here

  1. LaFramboise W, Dhir R, Kelly L, Petrosko P, Krill Burger J, Sciulli C, et al. Serum protein profiles predict coronary artery disease in symptomatic patients referred for coronary angiography. BMC Med. 2012;10:157 pubmed publisher
  2. Moreira D, da Silva R, Vieira J, Fattah T, Lueneberg M, Gottschall C. Role of vascular inflammation in coronary artery disease: potential of anti-inflammatory drugs in the prevention of atherothrombosis. Inflammation and anti-inflammatory drugs in coronary artery disease. Am J Cardiovasc Drugs. 2015;15:1-11 pubmed publisher
    ..The blockage of other potential targets, such as the IL-6 receptor, CC2 chemokine receptor and CD20, could bring benefits in CAD. ..
  3. Kocyigit D, Tokgozoglu L, Kayikcioglu M, Altay S, Aydogdu S, Barcin C, et al. Is there a gender gap in secondary prevention of coronary artery disease in Turkey?. Turk Kardiyol Dern Ars. 2018;46:683-691 pubmed publisher
    ..This highlights the importance of the implementation of lifestyle measures and adherence to medications in women. ..
  4. Elmaci I, Altinoz M. Targeting the cellular schizophrenia. Likely employment of the antipsychotic agent pimozide in treatment of refractory cancers and glioblastoma. Crit Rev Oncol Hematol. 2018;128:96-109 pubmed publisher
  5. Wang S, Yu T, Tsai F, Weston C, Lin M, Hung C, et al. Inhibition of semicarbazide-sensitive amine oxidase reduces atherosclerosis in apolipoprotein E-deficient mice. Transl Res. 2018;197:12-31 pubmed publisher
    ..Our data suggest that plasma VAP-1/SSAO is a novel biomarker for the presence and the extent of CAD in humans. VAP-1/SSAO inhibition by PXS-4728A is a potential treatment for atherosclerosis. ..
  6. Boratyńska M, Wakulenko A, Klinger M, Szyber P. Chronic allograft dysfunction in kidney transplant recipients: long-term single-center study. Transplant Proc. 2014;46:2673-7 pubmed publisher
    ..Proteinuria, serum creatinine level >1.5 mg/dL at 12th and 24th month, and CMV infections were identified as the most significant CAD progression factors. CAD had detrimental effects both on graft and patient survival rates. ..
  7. Horckmans M, Bianchini M, Santovito D, Megens R, Springael J, Negri I, et al. Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction. Circulation. 2018;137:948-960 pubmed publisher
    ..Our findings unveil a new mechanism by which the pericardial AT coordinates immune cell activation, granulopoiesis, and outcome after MI. ..
  8. Mahendra J, Mahendra L, Nagarajan A, Mathew K. Prevalence of eight putative periodontal pathogens in atherosclerotic plaque of coronary artery disease patients and comparing them with noncardiac subjects: A case-control study. Indian J Dent Res. 2015;26:189-95 pubmed publisher
    ..Further, the number of bacteria was significantly associated between the subgingival and atherosclerotic plaques of the cardiac patients in south Indian population. ..
  9. Kennedy D, Okello E, Chazot P, Howes M, Ohiomokhare S, Jackson P, et al. Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central Nervous System Function. Nutrients. 2018;10: pubmed publisher
    ..Future investigations should consider investigating higher doses. ..
  10. Naito C, Hashimoto M, Watanabe K, Shirai R, Takahashi Y, Kojima M, et al. Facilitatory effects of fetuin-A on atherosclerosis. Atherosclerosis. 2016;246:344-51 pubmed publisher
    ..Our results indicate that fetuin-A exerts the stimulatory effects on inflammatory responses in HUVECs, macrophage foam cell formation, and proliferation and collagen production in HASMCs, leading to the development of atherosclerosis. ..
  11. Zhong R, Xiao J, Dai C, Yu Z. [Regulation of paxillin tyrosine phosphorylation via inhibition of c-Abl kinase to protect ventilator induce lung injury in vivo in rats]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017;29:596-601 pubmed publisher
  12. Chen C, Holbrook M, Duess M, Dohadwala M, Hamburg N, Asztalos B, et al. Effect of almond consumption on vascular function in patients with coronary artery disease: a randomized, controlled, cross-over trial. Nutr J. 2015;14:61 pubmed publisher
    ..The trial was registered with the ClinicalTrials.Gov with the identifier: NCT00782015. ..
  13. Hoffmann U, Akers S, Brown R, Cummings K, Cury R, Greenberg S, et al. ACR Appropriateness Criteria Acute Nonspecific Chest Pain-Low Probability of Coronary Artery Disease. J Am Coll Radiol. 2015;12:1266-71 pubmed publisher
    ..This recommendation is based on excellent evidence, including several randomized comparative effectiveness trials and blinded observational cohort studies. ..
  14. Liu M, Liu Z, Cai H, Guo C, Li X, Zhang C, et al. A Model To Identify Individuals at High Risk for Esophageal Squamous Cell Carcinoma and Precancerous Lesions in Regions of High Prevalence in China. Clin Gastroenterol Hepatol. 2017;15:1538-1546.e7 pubmed publisher
    ..This model might be used to select individuals and groups of persons who should undergo endoscopy analysis for esophageal cancer. ..
  15. Tsikas D, Hanff E, Bollenbach A, Kruger R, Pham V, Chobanyan Jürgens K, et al. Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings. Amino Acids. 2018;50:799-821 pubmed publisher
    ..369). In LEW.1AR1-iddm rats, mean UNOxR values were lower than in healthy rats (198 vs. 308) and comparable to those in APOE*3-Leiden.CETP mice (151). ..
  16. Avinash S, Singh V, Agarwal A, Chatterjee S, Araya V. Identification and Stratification of Diabetic Kidney Disease Using Serum Cystatin C and Serum Creatinine Based Estimating Equations in Type 2 Diabetes: A Comparative Analysis. J Assoc Physicians India. 2015;63:28-35 pubmed
  17. Risal A, Manandhar K, Holen A, Steiner T, Linde M. Comorbidities of psychiatric and headache disorders in Nepal: implications from a nationwide population-based study. J Headache Pain. 2016;17:45 pubmed publisher
    ..These findings call for reciprocal awareness, and a holistic coordinated approach to management and in the health service. Care for common headache and common psychiatric disorders should be integrated in primary care. ..
  18. Cheng Q, Shang Y. ORMDL3 may participate in the pathogenesis of bronchial epithelial?mesenchymal transition in asthmatic mice with airway remodeling. Mol Med Rep. 2018;17:995-1005 pubmed publisher
    ..Transfection of ORMDL3 into 16HBE 14o?cells in vitro induced EMT. Taken together, these findings suggest that ORMDL3 may regulate EMT in the bronchial epithelium, thereby affecting airway remodeling in asthma. ..
  19. Soubassi L, Papadakis E, Theodoropoulos I, Poulos G, Chaniotis D, Tsapakidis I, et al. Incidence and risk factors of coronary artery disease in patients on chronic hemodialysis. Int J Artif Organs. 2007;30:253-7 pubmed
    ..The incidence of CAD in dialysis pts is significantly increased with age, male sex, obesity, time on dialysis, the presence of anemia, hyperhomocysteinemia and inadequacy of HD...
  20. Fang S, Guo H, Cheng Y, Zhou Z, Zhang W, Han B, et al. circHECTD1 promotes the silica-induced pulmonary endothelial-mesenchymal transition via HECTD1. Cell Death Dis. 2018;9:396 pubmed publisher
    ..Our findings reveal a potentially new function for the circHECTD1/HECTD1 pathway and suggest a possible mechanism of fibrosis in patients with pulmonary silicosis. ..
  21. Badin J, Kole A, Stivers B, Progar V, Pareddy A, Alloosh M, et al. Alloxan-induced diabetes exacerbates coronary atherosclerosis and calcification in Ossabaw miniature swine with metabolic syndrome. J Transl Med. 2018;16:58 pubmed publisher
    ..These results recapitulate increased CAD in humans with diabetes and establish Ossabaw miniature swine as an animal model for future MetS/diabetes comorbidity studies. ..
  22. van Tilborg M, Al Marzooqi S, Wong W, Maan R, Vermehren J, Maasoumy B, et al. HCV core antigen as an alternative to HCV RNA testing in the era of direct-acting antivirals: retrospective screening and diagnostic cohort studies. Lancet Gastroenterol Hepatol. 2018;3:856-864 pubmed publisher
    ..This approach might improve access to care, particularly in low-income and middle-income countries. Abbott Diagnostics and Toronto Centre for Liver Disease. ..
  23. Pleuger C, Fietz D, Hartmann K, Schuppe H, Weidner W, Kliesch S, et al. Expression of ciliated bronchial epithelium 1 during human spermatogenesis. Fertil Steril. 2017;108:47-54 pubmed publisher
    ..The absence of CBE1 in spermatozoa suggests that CBE1 is important for the spermatid development but not for the maintenance of mature spermatozoa as a component of the flagellum. ..
  24. Santolim L, Amaral M, Fachi J, Mendes M, Oliveira C. Vitamin E and caloric restriction promote hepatic homeostasis through expression of connexin 26, N-cad, E-cad and cholesterol metabolism genes. J Nutr Biochem. 2017;39:86-92 pubmed publisher
    ..Finally, vitamin E, with or without CR, increased Cx26, probably modulated by expression of the Hmgcr and LDLr genes. This suggests important relationship of Cxs and cholesterol metabolism genes. ..
  25. Mangla A, Oliveros E, Williams K, Kalra D. Cardiac Imaging in the Diagnosis of Coronary Artery Disease. Curr Probl Cardiol. 2017;42:316-366 pubmed publisher
  26. Samman Tahhan A, Hammadah M, Raad M, Almuwaqqat Z, Alkhoder A, Sandesara P, et al. Progenitor Cells and Clinical Outcomes in Patients With Acute Coronary Syndromes. Circ Res. 2018;122:1565-1575 pubmed publisher
    ..Among patients with ACS, a lower number of hematopoietic-enriched CPCs are associated with a higher mortality. ..
  27. Mello C, Santiago Junior J, Galhano G, Quinelli Mazaro J, Scotti R, Pellizzer E. Analysis of Vertical Marginal Adaptation of Zirconia Fixed Dental Prosthesis Frameworks Fabricated by the CAD/CAM System: A Randomized, Double-Blind Study. Int J Prosthodont. 2016;29:157-60 pubmed publisher
    ..05). The CAD/CAM systems showed less marginal discrepancy than the conventional method for the fabrication of the frameworks. ..
  28. Fekrazad R, Poorsattar Bejeh Mir A, Kahyaie Aghdam M, Ghasemi Barghi V. Comparison of photoinactivation of T. rubrum by new methylene blue (NMB) and indocyanine green (EmunDo®). Photodiagnosis Photodyn Ther. 2017;18:208-212 pubmed publisher
    ..Irradiation by only red laser source was found superior to only infra-red laser source. Dark toxicity of EmunDo® was more successful than new methylene blue dye. ..
  29. Cardoso D, Moreira A, de Oliveira G, Raggio Luiz R, Rosa G. A COCONUT EXTRA VIRGIN OIL-RICH DIET INCREASES HDL CHOLESTEROL AND DECREASES WAIST CIRCUMFERENCE AND BODY MASS IN CORONARY ARTERY DISEASE PATIENTS. Nutr Hosp. 2015;32:2144-52 pubmed publisher
    ..Conclusión: se observó que el tratamiento nutricional asociado con el consumo de aceite de coco virgen extra redujo la CC e incrementó los niveles de HDL-C en pacientes con CAD. ..
  30. Alai M, Beig J, Kumar S, Yaqoob I, Hafeez I, Lone A, et al. Prevalence and characterization of coronary artery disease in patients with symptomatic bradyarrhythmias requiring pacemaker implantation. Indian Heart J. 2016;68 Suppl 3:S21-S25 pubmed publisher
    ..It could be argued that such patients should undergo a coronary work-up before pacemaker implantation. Treatment of concomitant CAD is likely to improve the long term prognosis of these patients. ..
  31. Paradis J, White J, Genereux P, Urena M, Doshi D, Nazif T, et al. Impact of Coronary Artery Disease Severity Assessed With the SYNTAX Score on Outcomes Following Transcatheter Aortic Valve Replacement. J Am Heart Assoc. 2017;6: pubmed publisher
    ..In our core laboratory-validated study, neither the severity of CAD nor completeness of revascularization after percutaneous coronary intervention or CABG were associated with clinical outcomes after TAVR, at both 30 days and 1 year. ..
  32. Bueno H, Pocock S, Medina J, Danchin N, Annemans L, Licour M, et al. Association Between Clinical Pathways Leading to Medical Management and Prognosis in Patients With NSTEACS. Rev Esp Cardiol (Engl Ed). 2017;70:817-824 pubmed publisher
    ..Medically managed NSTEACS patients represent a heterogeneous population with distinct risk profiles and outcomes. These differences should be considered when designing future studies in this population. ..
  33. Bowman K, Atkins J, Delgado J, Kos K, Kuchel G, Ble A, et al. Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants. Am J Clin Nutr. 2017;106:130-135 pubmed publisher
    ..The claimed BMI-defined overweight risk paradox may result in part from failing to account for central adiposity, rather than reflecting a protective physiologic effect of higher body-fat content in later life. ..
  34. Papadiochou S, Pissiotis A. Marginal adaptation and CAD-CAM technology: A systematic review of restorative material and fabrication techniques. J Prosthet Dent. 2018;119:545-551 pubmed publisher
    ..No clear conclusions can be drawn about the superiority of CAD-CAM milling over the casting technique and DMLS regarding marginal adaptation. ..
  35. Longo F, Nicetto T, Banzato T, Savio G, Drigo M, Meneghello R, et al. Automated computation of femoral angles in dogs from three-dimensional computed tomography reconstructions: Comparison with manual techniques. Vet J. 2018;232:6-12 pubmed publisher
    ..8). The computation of the 3D aCAD method provided the highest repeatability and reproducibility among the tested methodologies. ..
  36. Sanidas E, Papaioannou T, Papadopoulos D, Tatsi K, Velliou M, Dalianis N, et al. The impact of financial crisis on coronary artery disease burden in Greece. Hellenic J Cardiol. 2018;: pubmed publisher
    ..It seems that the impact of traditional risk factors for CAD is not an immediate process and is somewhat related to living conditions or other exogenous and social factors. ..
  37. Litjens G, Barentsz J, Karssemeijer N, Huisman H. Clinical evaluation of a computer-aided diagnosis system for determining cancer aggressiveness in prostate MRI. Eur Radiol. 2015;25:3187-99 pubmed publisher
    ..Combining PIRADS and computer-aided diagnosis improves differentiation between indolent and aggressive cancer. • Adding computer-aided diagnosis to PIRADS increases the correlation coefficient with respect to cancer grade. ..
  38. Shirai T, Nazarewicz R, Wallis B, Yanes R, Watanabe R, Hilhorst M, et al. The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease. J Exp Med. 2016;213:337-54 pubmed publisher
    ..In essence, PKM2 serves a previously unidentified role as a molecular integrator of metabolic dysfunction, oxidative stress and tissue inflammation and represents a novel therapeutic target in cardiovascular disease. ..
  39. Opstad T, Arnesen H, Pettersen A, Seljeflot I. Combined Elevated Levels of the Proinflammatory Cytokines IL-18 and IL-12 Are Associated with Clinical Events in Patients with Coronary Artery Disease: An Observational Study. Metab Syndr Relat Disord. 2016;14:242-8 pubmed publisher
    ..009) and IL-12 levels was considerably lower in current smokers (adjusted P?<?0.001). Simultaneous elevated circulating levels of IL-18 and IL-12 increased the event rate after 2 years in CAD patients, independent of hyperglycemia. ..
  40. Zhang L, Wei T, Li Y, Li J, Fan Y, Huang F, et al. Functional Metabolomics Characterizes a Key Role for N-Acetylneuraminic Acid in Coronary Artery Diseases. Circulation. 2018;137:1374-1390 pubmed publisher
    ..Functional metabolomics identified a key role for Neu5Ac in acute myocardial infarction, and targeting neuraminidase-1 may represent an unrecognized therapeutic intervention for CAD. ..
  41. Ljungberg J, Janiec M, Bergdahl I, Holmgren A, Hultdin J, Johansson B, et al. Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement. Circulation. 2018;: pubmed publisher
    ..b>Conclusions -We provide evidence that five proteins were altered years before AS surgery and that the associations seem to be driven by concurrent atherosclerotic disease. ..
  42. Ripley D, Motwani M, Brown J, Nixon J, Everett C, Bijsterveld P, et al. Individual component analysis of the multi-parametric cardiovascular magnetic resonance protocol in the CE-MARC trial. J Cardiovasc Magn Reson. 2015;17:59 pubmed publisher
    ..The LGE component alone was the optimal rule-in strategy. Finally the inclusion of coronary MRA provided no additional benefit when compared to the combination of perfusion/function/LGE. Current Controlled Trials ISRCTN77246133. ..
  43. Gretarsdottir S, Helgason H, Helgadottir A, Sigurdsson A, Thorleifsson G, Magnusdottir A, et al. A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease. PLoS Genet. 2015;11:e1005379 pubmed publisher
    ..This demonstrates that sequence variants that disrupt the LDL receptor can lower non-HDL-C and protect against CAD. ..
  44. Wu L, Zhao M, Geng G, Mao L, Liu H. Statistical analysis of the relationship between IL-10 gene promoter polymorphisms and the development of coronary artery disease. Genet Mol Res. 2016;15: pubmed publisher
    ..In conclusion, our study suggests that the IL-10-1082A/G genetic variation could influence the development of CAD in a Chinese population. ..
  45. Markl D, Zeitler J, Rasch C, Michaelsen M, Mullertz A, Rantanen J, et al. Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging. Pharm Res. 2017;34:1037-1052 pubmed publisher
    ..The microstructural information extracted by X?CT and TPI will assist to gain a better understanding about the performance of 3D printed dosage forms. ..
  46. Dawson J, Hyde B, Hurst M, Harris B, Lin W. Polyetherketoneketone (PEKK), a framework material for complete fixed and removable dental prostheses: A clinical report. J Prosthet Dent. 2018;119:867-872 pubmed publisher
    ..The performance of PEKK as a framework material needs to be assessed in clinical trials. ..
  47. Ouyang H, Xie P, Deng Y, Yang Y, Chen P, Huang H, et al. [Finite element modeling of material property assignment based on CT gray value and its application in simulation of osteotomy for deformities]. Nan Fang Yi Ke Da Xue Xue Bao. 2016;36:979-83 pubmed
  48. Ballocca F, D Ascenzo F, Moretti C, Diletti R, Budano C, Palazzuoli A, et al. High sensitive TROponin levels In Patients with Chest pain and kidney disease: A multicenter registry - The TROPIC study. Cardiol J. 2017;24:139-150 pubmed publisher
    ..Peak level of both troponin assays predicts events at 30 days, with troponin I being more accurate than troponin T. (Cardiol J 2017; 24, 2: 139-150). ..
  49. Drennan C, DeOtte R, Lawrence T. Documentation of 50% water conservation in a single process at a beef abattoir. Meat Sci. 2017;131:183-186 pubmed publisher
    ..Prior to altering operating parameters, the post-wash red saturation was 5%; after modification this increased slightly to 7.5%. Water use was reduced by 48.4% without altering head cleanliness acceptance. ..
  50. Deseive S, Straub R, Kupke M, Broersen A, Kitslaar P, Massberg S, et al. Quantification of coronary low-attenuation plaque volume for long-term prediction of cardiac events and reclassification of patients. J Cardiovasc Comput Tomogr. 2018;12:118-124 pubmed publisher
    ..5%) patients as high risk (annual event rate 0.99%). Quantification of LAPV provides incremental prognostic information beyond established CT risk patterns and permits improved stratification of patients into different risk categories. ..
  51. Plank F, Beyer C, Friedrich G, Stuhlinger M, Hintringer F, Dichtl W, et al. Influence of vitamin K antagonists and direct oral anticoagulation on coronary artery disease: A CTA analysis. Int J Cardiol. 2018;260:11-15 pubmed publisher
    ..014) and napkin-ring sign (0 vs. 5.0%, p = 0.029). Vitamin K antagonists are associated with a higher plaque burden and increased high-risk plaque features, whereas DOACs may yield a benefit in cardiovascular atherosclerosis. ..
  52. Enevoldsen L, Heaf J, Højgaard L, Zerahn B, Hasbak P. Increased technetium-99 m hydroxy diphosphonate soft tissue uptake on bone scintigraphy in chronic kidney disease patients with secondary hyperparathyroidism: correlation with hyperphosphataemia. Clin Physiol Funct Imaging. 2017;37:131-136 pubmed publisher
    ..In conclusion, dialysis-treated CKD patients with secondary hyperparathyroidism have a high incidence of soft tissue uptake, and this finding is strongly correlated with elevated phosphate, but not calcium values. ..
  53. Hirata Y, Yamada H, Kusunose K, Iwase T, Nishio S, Hayashi S, et al. Clinical Utility of Measuring Epicardial Adipose Tissue Thickness with Echocardiography Using a High-Frequency Linear Probe in Patients with Coronary Artery Disease. J Am Soc Echocardiogr. 2015;28:1240-1246.e1 pubmed publisher
    ..EAT-AIG was thicker in the CAD group than in the non-CAD group, as was EAT-RV thickness. This noninvasive index may have potential as a diagnostic marker for predicting coronary atherosclerosis. ..
  54. Kim K, Lim S, Moon J, Jin H, Jung K, Shin C, et al. Lower uncarboxylated osteocalcin and higher sclerostin levels are significantly associated with coronary artery disease. Bone. 2016;83:178-183 pubmed publisher
    ..Longitudinal studies are warranted to establish the precise roles of ucOCN and sclerostin in the pathogenesis of atherosclerosis. ..
  55. Cox J, Hamelin A, McLinden T, Moodie E, Anema A, Rollet Kurhajec K, et al. Food Insecurity in HIV-Hepatitis C Virus Co-infected Individuals in Canada: The Importance of Co-morbidities. AIDS Behav. 2017;21:792-802 pubmed publisher
    ..Engagement of co-infected individuals in substance use treatments, harm reduction programs, and mental health services may mitigate FI in this vulnerable subset of the HIV-positive population. ..
  56. Farjood E, Vojdani M, Torabi K, Khaledi A. Marginal and internal fit of metal copings fabricated with rapid prototyping and conventional waxing. J Prosthet Dent. 2017;117:164-170 pubmed publisher
    ..However, the marginal and internal fit for both groups were within clinically acceptable ranges. ..
  57. Kang S, Park G, Lee S, Yun S, Kim Y, Cho Y, et al. Long-Term Prognostic Value of Coronary CT Angiography in Asymptomatic Type 2 Diabetes Mellitus. JACC Cardiovasc Imaging. 2016;9:1292-1300 pubmed publisher
    ..These findings suggest long-term prognostic value of coronary CTA for asymptomatic type 2 diabetes mellitus. ..
  58. Harada M, Miura T, Kobayashi T, Kobayashi H, Kobayashi M, Nakajima H, et al. Clinical impact of complete revascularization in elderly patients with multi-vessel coronary artery disease undergoing percutaneous coronary intervention: A sub-analysis of the SHINANO registry. Int J Cardiol. 2017;230:413-419 pubmed publisher
    ..2% vs. 18.4%, p=0.015). Even in elderly patients over 75years old with multi-vessel CAD, CR-PCI appears to suppress mid-term ischemic events. ..
  59. Juárez Rojas J, Posadas Sánchez R, Martínez Alvarado M, Torres Tamayo M, Jorge Galarza E, Mancilla Valenzuela E, et al. Association of Adiponectin with Subclinical Atherosclerosis in a Mexican-Mestizo Population. Arch Med Res. 2017;48:73-78 pubmed publisher
    ..505 [1.051-2.153]). In the studied population, low adiponectin concentrations are associated with a higher prevalence of subclinical atherosclerosis, independent of traditional cardiovascular risk factors. ..
  60. Cabezas J, González Martínez S, Collada C, Guevara M, Boury C, de María N, et al. Nucleotide polymorphisms in a pine ortholog of the Arabidopsis degrading enzyme cellulase KORRIGAN are associated with early growth performance in Pinus pinaster. Tree Physiol. 2015;35:1000-6 pubmed publisher
    ..1, lp3.3 and cad were included in RR-BLUP models. These results point towards a desirable integration of candidate-gene studies as a means to pre-select relevant markers, and aid genomic selection in maritime pine breeding programs. ..
  61. Bouzas Mosquera M, Bouzas Mosquera A, Peteiro J. Excessive blood pressure increase with exercise and risk of all-cause mortality and cardiac events. Eur J Clin Invest. 2016;46:833-9 pubmed publisher
    ..An EBPIE was associated with a significantly lower risk of mortality and MACE in patients with known or suspected CAD referred for stress testing. ..
  62. Zhang L, Wu W, Ma H, Wang H. Usefulness of layer-specific strain for identifying complex CAD and predicting the severity of coronary lesions in patients with non-ST-segment elevation acute coronary syndrome: Compared with Syntax score. Int J Cardiol. 2016;223:1045-1052 pubmed publisher
    ..05). Strains, particularly endocardial GLS and TLS measurement by 2DSTE might enable a non-invasive method to identify complex CAD and predict the severity of coronary lesions in patients with NSTE-ACS. ..
  63. Li S, Li H, Yuan Z, Zhang B, Chen A, Zhou M, et al. Off-pump coronary artery bypass surgery outcomes in patients with ischaemic left ventricular systolic dysfunction with or without detected viable myocardium. Interact Cardiovasc Thorac Surg. 2017;25:218-224 pubmed publisher
    ..The present study evaluated the effects of off-pump coronary artery bypass (OPCAB) grafting on patients with coronary artery disease (CAD) with or without viable myocardium (VM) preoperatively detected via nuclear imaging...
  64. Mahajan A, Surti N, Koladiya P. Solid dispersion adsorbate technique for improved dissolution and flow properties of lurasidone hydrochloride: characterization using 32 factorial design. Drug Dev Ind Pharm. 2018;44:463-471 pubmed publisher
  65. Ukena C, Mahfoud F, Kindermann M, Kindermann I, Bals R, Voors A, et al. The cardiopulmonary continuum systemic inflammation as 'common soil' of heart and lung disease. Int J Cardiol. 2010;145:172-176 pubmed publisher
    ..These complex interactions between heart and lung can be denoted as 'cardiopulmonary continuum'. Common risk factors induce systemic inflammatory processes which lead to progression of atherosclerotic diseases as well as COPD. ..
  66. Shao B, Heinecke J. Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathway. J Proteomics. 2011;74:2289-99 pubmed publisher
    ..Thus, the presence of chlorinated HDL might serve as a marker of CAD risk. Because HDL damaged by MPO in vitro becomes dysfunctional, inhibiting MPO in vivo might be cardioprotective...
  67. Bal Z, Bal U, Okyay K, Yilmaz M, Balcioglu S, Turgay O, et al. Hematological parameters can predict the extent of coronary artery disease in patients with end-stage renal disease. Int Urol Nephrol. 2015;47:1719-25 pubmed publisher
    ..001), NLR (p = 0.001), and MPV (p = 0.005) were independent predictors of the extent of CAD. Aside from the well-known traditional factors, NLR and MPV are independent predictors of the extent of CAD in patients with ESRD. ..
  68. Wimmer T, Huffmann A, Eichberger M, Schmidlin P, Stawarczyk B. Two-body wear rate of PEEK, CAD/CAM resin composite and PMMA: Effect of specimen geometries, antagonist materials and test set-up configuration. Dent Mater. 2016;32:e127-36 pubmed publisher
    ..Wear of PEEK was lower than that of the resin-based materials when lateral forces were applied, but showed comparable antagonist wear rates at the same time. ..
  69. Hoogslag G, Joyce E, Bax J, Ajmone Marsan N, Delgado V. Assessment of global left ventricular excursion using three-dimensional dobutamine stress echocardiography to identify significant coronary artery disease. Echocardiography. 2016;33:1532-1538 pubmed publisher
    ..29, 95% confidence interval 0.12-0.72, P=.008). Analysis of 3D echocardiographic LV excursion at global level on full-protocol DSE may be a helpful tool to detect CAD on coronary angiography. ..
  70. Boxio R, Wartelle J, Nawrocki Raby B, Lagrange B, Malleret L, Hirche T, et al. Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epithelium. Respir Res. 2016;17:129 pubmed
    ..These data suggest a mechanism by which unchecked NE participates potentially to the pathogenesis of neutrophil-rich lung inflammatory and tissue-destructive diseases. ..
  71. Schauerte C, Hübner A, Rong S, Wang S, Shushakova N, Mengel M, et al. Antagonism of profibrotic microRNA-21 improves outcome of murine chronic renal allograft dysfunction. Kidney Int. 2017;92:646-656 pubmed publisher
    ..miR-21a-5p silencing may therefore be a viable therapeutic option in the treatment of patients following kidney transplantation to halt the development of CAD. ..
  72. Shao X, Wang Y, Wang J, Zhou R, Ke H, Yang Y. Characteristics of coronary artery calcium and its relationship to myocardial ischemia in Chinese patients with suspected coronary artery disease. Hell J Nucl Med. 2016;19:105-10 pubmed publisher
    ..CACS was weakly correlated with ischemic MPI, the accuracy of the presence of CAC for predicting ischemic MPI was low. CACS was not a reliable screening tool prior to MPI in Chinese patients with SCAD. ..
  73. Niinaga R, Yamamoto H, Yoshii M, Uekita H, Yamane N, Kochi I, et al. Marked elevation of serum M2BP-adiponectin complex in men with coronary artery disease. Atherosclerosis. 2016;253:70-74 pubmed publisher
    ..The increment of serum M2BP-APN complex could be a novel risk factor for CAD, through the abolishment of the anti-atherogenic effects of APN. ..
  74. Joseph P, Pare G, Asma S, Engert J, Yusuf S, Anand S. Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations. Can J Cardiol. 2016;32:1440-1446 pubmed publisher
    ..A CAD GRS is associated with MI across a multiethnic cohort, with significant and consistent effects across 4 distinct ethnicities. However, it only modestly improves MI risk prediction beyond clinical factors. ..
  75. Quercioli A, Carbone F, Bonaventura A, Liberale L, Pataky Z, Thomas A, et al. Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function. Int J Cardiol. 2017;231:1-5 pubmed publisher
    ..Larger trials are needed to confirm PEA as a potential circulating biomarker of coronary dysfunction in both MOB patients and the general population. ..
  76. Lima E, Carvalho F, Linhares Filho J, Pitta F, Serrano C. Ischemic left ventricle systolic dysfunction: An evidence-based approach in diagnostic tools and therapeutics. Rev Assoc Med Bras (1992). 2017;63:793-800 pubmed publisher
    ..Finally, authors discuss interventional procedures in this population, focusing on coronary artery bypass grafting and evolution of evidence from CASS to post-STICH era...
  77. Morgan C, Diaz J, Zeitlin S, Gray D, Wells J. Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling. Proc Natl Acad Sci U S A. 2015;112:8344-9 pubmed publisher
    ..Furthermore, the PTGR approach provides a general means for replacing wild-type protein function with a precisely engineered mutant at the transcriptional level that should be useful for cell engineering studies. ..
  78. Berezin A, Kremzer A, Samura T. Circulating thrombospondine-2 in patients with moderate-to-severe chronic heart failure due to coronary artery disease. J Biomed Res. 2015;30: pubmed publisher
    ..12; 95%CI=1.07-1.25; P<0.001). In conclusion, among CAD patients with symptomatic CHF, increased circulating TSP-2 is correlated with increased 3-year CHF-related death, all-cause mortality, and risk for recurrent hospitalization. ..
  79. Riaz F, Hassan A, Nisar R, Dinis Ribeiro M, Coimbra M. Content-Adaptive Region-Based Color Texture Descriptors for Medical Images. IEEE J Biomed Health Inform. 2017;21:162-171 pubmed publisher
    ..e., gastroenterology and dermoscopy . Experiments demonstrate that the proposed descriptors compares favorably to several other state-of-the-art methods, elucidating on the effectiveness of adapted features for image characterization...
  80. Saras A, Tanouye M. Seizure Suppression by High Temperature via cAMP Modulation in Drosophila. G3 (Bethesda). 2016;6:3381-3387 pubmed publisher
    ..In summary, we describe an unusual phenomenon, where high temperature can suppress SLA in flies by modulating cAMP concentration. ..
  81. Kern J, Wolfart S, Hilgers R, Marré B, Scheller H, Strub J, et al. The randomized shortened dental arch study: influence of two different treatments on interdental spacing over 5 years. Clin Oral Investig. 2017;21:1945-1951 pubmed publisher
    ..Major interdental spacing could be observed in neither of the groups. The SDA concept resulted in a slightly better outcome. When deciding whether to replace missing molars, the present results give further support to the SDA concept. ..
  82. Saleem M, Herrmann N, Dinoff A, Mielke M, Oh P, Shammi P, et al. A Lipidomics Approach to Assess the Association Between Plasma Sphingolipids and Verbal Memory Performance in Coronary Artery Disease Patients Undertaking Cardiac Rehabilitation: A C18:0 Signature for Cognitive Response to Exercise. J Alzheimers Dis. 2017;60:829-841 pubmed publisher
    ..Sphingolipids have been associated with the development and progression of CAD, and impairments in sphingolipid metabolism may play roles in neurodegeneration and in the neural adaptation response to exercise...
  83. Desperak P, Hawranek M, Gasior P, Desperak A, Lekston A, Gasior M. Long-term outcomes of patients with multivessel coronary artery disease presenting non-ST-segment elevation acute coronary syndromes. Cardiol J. 2019;26:157-168 pubmed publisher
    ..Performance of PCI is an independent factor for improving long-term prognosis. ..
  84. Lai H, Li X, Yang Y, Ma Y, Xu R, Pan S, et al. Genetic Variation in NFKB1 and NFKBIA and Susceptibility to Coronary Artery Disease in a Chinese Uygur Population. PLoS ONE. 2015;10:e0129144 pubmed publisher
  85. Ramos N, Campos T, Paz I, Machado J, Bottino M, Cesar P, et al. Microstructure characterization and SCG of newly engineered dental ceramics. Dent Mater. 2016;32:870-8 pubmed publisher
    ..The overall strength and SCG of the new materials did not benefit from the additional phase or microconstituents present in them. ..
  86. Sil S, Ghosh A, Ghosh T. Impairment of blood brain barrier is related with the neuroinflammation induced peripheral immune status in intracerebroventricular colchicine injected rats: An experimental study with mannitol. Brain Res. 2016;1646:278-286 pubmed publisher
    ..It can be concluded from this study that impairment of BBB in cAD rats is related to the changes of peripheral immune responses observed in that condition. ..
  87. Egilmez F, Ergun G, Cekic Nagas I, Vallittu P, Lassila L. Does artificial aging affect mechanical properties of CAD/CAM composite materials. J Prosthodont Res. 2018;62:65-74 pubmed publisher
    ..Cyclic loading or HCl exposure does not affect to the flexural strength and structural reliability of Cerasmartâ„¢ and Lavaâ„¢ Ultimate. ..
  88. Tani S, Yagi T, Atsumi W, Kawauchi K, Matsuo R, Hirayama A. Relation between low-density lipoprotein cholesterol/apolipoprotein B ratio and triglyceride-rich lipoproteins in patients with coronary artery disease and type 2 diabetes mellitus: a cross-sectional study. Cardiovasc Diabetol. 2017;16:123 pubmed publisher
    ..Further studies are needed to investigate the useful clinical indices and outcomes of these patients. Clinical Trial Registration UMIN (http://www.umin.ac.jp/) Study ID: UMIN000028029 retrospectively registered 1 July 2017. ..
  89. McLaughlin J, Ramos V, Dickinson D. Comparison of Fit of Dentures Fabricated by Traditional Techniques Versus CAD/CAM Technology. J Prosthodont. 2017;: pubmed publisher
    ..To compare the shrinkage of denture bases fabricated by three methods: CAD/CAM, compression molding, and injection molding. The effect of arch form and palate depth was also tested...
  90. Piller F, Blanchard D, Huet M, Cartron J. Identification of a alpha-NeuAc-(2----3)-beta-D-galactopyranosyl N-acetyl-beta-D-galactosaminyltransferase in human kidney. Carbohydr Res. 1986;149:171-84 pubmed
    ..When these structures were presented as sialyl-(2----3)-lactose or as a tryptic peptide from glycophorin A, they were shown to be rather good acceptor substrates for the N-acetyl-beta-D-galactosaminyltransferase from human kidney. ..
  91. Diamantis E, Kyriakos G, Quiles Sanchez L, Farmaki P, Troupis T. The Anti-Inflammatory Effects of Statins on Coronary Artery Disease: An Updated Review of the Literature. Curr Cardiol Rev. 2017;13:209-216 pubmed publisher
    ..It is well known that statins can actually reduce the circulating levels of these agents slowing therefore the inflammatory process; interestingly not all types have the same outcome...
  92. Li C, Zhao L, Jiang W, Che L, Xu Y. Correct microarray analysis approaches in 'Hsa-circRNA11783-2 in peripheral blood is correlated with coronary artery disease and type 2 diabetes mellitus'. Diab Vasc Dis Res. 2017;:1479164117739435 pubmed publisher
    ..Only selecting circular RNA with greater than two fold change with unadjusted p values < 0.05 in expression is not reliable and suitable for high-level microarray analysis...