B3GNT7

Summary

Gene Symbol: B3GNT7
Description: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
Alias: beta3GnT7, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7, BGnT-7, beta 1,3-N-acetylglucosaminyltransferase 7, beta-1,3-Gn-T7, beta3Gn-T7
Species: human
Products:     B3GNT7

Top Publications

  1. Canevari R, Marchi F, Domingues M, de Andrade V, Caldeira J, Verjovski Almeida S, et al. Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma. Tumour Biol. 2016;37:13855-13870 pubmed
    ..The upregulation of B3GNT7, PPM1D, TNKS2, PHB, and GTSE1 in patients with poor outcomes was confirmed by quantitative reverse transcription ..
  2. Seko A, Yamashita K. beta1,3-N-Acetylglucosaminyltransferase-7 (beta3Gn-T7) acts efficiently on keratan sulfate-related glycans. FEBS Lett. 2004;556:216-20 pubmed
    ..These results indicate that beta3Gn-T7 is the one that most efficiently elongates L2L2 and may be involved in the biosynthesis of keratan sulfate. ..
  3. Kitayama K, Hayashida Y, Nishida K, Akama T. Enzymes responsible for synthesis of corneal keratan sulfate glycosaminoglycans. J Biol Chem. 2007;282:30085-96 pubmed
    ..Here we analyzed enzymatic activity of two glycosyltransferases, beta1,3-N-acetylglucosaminyltansferase-7 (beta3GnT7) and beta1,4-galactosyltransferase-4 (beta4GalT4), in the production of keratan sulfate carbohydrate in vitro...
  4. Lu C, Wu W, Lai Y, Yang C, Yu L. Suppression of B3GNT7 gene expression in colon adenocarcinoma and its potential effect in the metastasis of colon cancer cells. Glycobiology. 2014;24:359-67 pubmed publisher
    ..In the present investigation, expression of the B3GNT7 gene, which encodes a ?-1,3-N-acetylglucosaminyltransferase that mainly acts on and extends sulfated poly-LacNAc ..
  5. Kataoka K, Huh N. A novel beta1,3-N-acetylglucosaminyltransferase involved in invasion of cancer cells as assayed in vitro. Biochem Biophys Res Commun. 2002;294:843-8 pubmed
    ..approximately 5 (beta3GnT2 approximately 5), and the protein was therefore named beta3GnT7. A possible human ortholog was identified and its chromosomal locus was determined to be 2q37.1...