Gene Symbol: ATP9B
Description: ATPase phospholipid transporting 9B (putative)
Alias: ATPASEP, ATPIIB, HUSSY-20, NEO1L, hMMR1, ATPase type IV, phospholipid transporting (P-type), ATPase, class II, type 9B, macrophage MHC receptor 1
Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, et al
. Characterization of 16 novel human genes showing high similarity to yeast sequences. Yeast. 2001;18:69-80 pubmed
..More information on this work can be obtained at the website http://grup.bio.unipd.it/hussy ..
Takatsu H, Baba K, Shima T, Umino H, Kato U, Umeda M, et al
. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. J Biol Chem. 2011;286:38159-67 pubmed publisher
..In contrast, class 2 P4-ATPases (ATP9A and ATP9B) are able to exit the ER in the absence of exogenous CDC50 expression: ATP9B, but not ATP11B, was able to exit the ..
Halleck M, Pradhan D, Blackman C, Berkes C, Williamson P, Schlegel R. Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs. Genome Res. 1998;8:354-61 pubmed
Halleck M, Lawler JF J, Blackshaw S, Gao L, Nagarajan P, Hacker C, et al
. Differential expression of putative transbilayer amphipath transporters. Physiol Genomics. 1999;1:139-50 pubmed
..These results suggest that the genes are expressed in a tissue-specific manner, are not simply redundant, and may represent isoforms that transport a variety of different amphipaths...
Nusbaum C, Zody M, Borowsky M, Kamal M, Kodira C, Taylor T, et al
. DNA sequence and analysis of human chromosome 18. Nature. 2005;437:551-5 pubmed
..This has important implications for the nature and roles of non-protein-coding sequence elements. ..
Tashiro Yamaji J, Shimizu T, Hayashi M, Yamana H, Tanigawa N, Uchiyama K, et al
. Specific binding of HLA-B44 to human macrophage MHC receptor 1 on monocytes. Gene. 2012;501:127-34 pubmed publisher
..mice exhibit major histocompatibility complex (MHC) haplotype-specific killing of allografts in a macrophage MHC receptor 1 (MMR1; for H-2D(d))- and MMR2 (for H-2K(d))-dependent manner...
van Beek N, Patsatsi A, Gupta Y, Möller S, Freitag M, Lemcke S, et al
. A family with atypical Hailey Hailey disease--is there more to the underlying genetics than ATP2C1?. PLoS ONE. 2015;10:e0121253 pubmed publisher
..7 additional SNPs in 4 ATPase genes (ATP9B, ATP11A, ATP2B3 and ATP13A5) were identified...
Barber R, Phillips N, Tilson J, Huebinger R, Shewale S, Koenig J, et al
. Can Genetic Analysis of Putative Blood Alzheimer's Disease Biomarkers Lead to Identification of Susceptibility Loci?. PLoS ONE. 2015;10:e0142360 pubmed publisher
..Additional signals were observed in MAP3K13, ZNF320, ATP9B and TREM1...
Zhou Z, Du D, Huang G, Chen A, Zhu L. Circular RNA Atp9b, a competing endogenous RNA, regulates the progression of osteoarthritis by targeting miR-138-5p. Gene. 2018;646:203-209 pubmed publisher
..Our findings provide novel insight into the regulatory mechanism of circRNA_Atp9b in OA and may contribute to establishing potential therapeutic strategies. ..