Gene Symbol: ATP8B3
Description: ATPase phospholipid transporting 8B3
Alias: ATPIK, phospholipid-transporting ATPase IK, ATPase, aminophospholipid transporter, class I, type 8B, member 3, ATPase, class I, type 8B, member 3, aminophospholipid translocase ATP8B3, potential phospholipid-transporting ATPase IK
Wang J, Molday L, Hii T, Coleman J, Wen T, Andersen J, et al
. Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues. Sci Rep. 2018;8:10795 pubmed publisher
..ATP8B1 was detected only in liver, ATP8B3 and ATP10A only in testes, and ATP8B2 primarily in brain...
Atikuzzaman M, Alvarez Rodriguez M, Vicente Carrillo A, Johnsson M, Wright D, Rodriguez Martinez H. Conserved gene expression in sperm reservoirs between birds and mammals in response to mating. BMC Genomics. 2017;18:98 pubmed publisher
..genes were found in both the chicken and pig, either involved in pH-regulation (SLC16A2, SLC4A9, SLC13A1, SLC35F1, ATP8B3, ATP13A3) or immune-modulation (IFIT5, IFI16, MMP27, ADAMTS3, MMP3, MMP12)...
Fries A, Svendsen O. Studies on Tyzzer's disease in rats. Lab Anim. 1978;12:1-4 pubmed
..By testing sera from healthy rats in 3 different colonies by use of immunofluorescence technique, antibodies were found in several sera. ..
Halleck M, Lawler JF J, Blackshaw S, Gao L, Nagarajan P, Hacker C, et al
. Differential expression of putative transbilayer amphipath transporters. Physiol Genomics. 1999;1:139-50 pubmed
..These results suggest that the genes are expressed in a tissue-specific manner, are not simply redundant, and may represent isoforms that transport a variety of different amphipaths...
Harris M, Arias I. FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body. Biochim Biophys Acta. 2003;1633:127-31 pubmed
..We identified two familial intrahepatic cholestasis type 1 (FIC1) homologues, ATP8B2 and ATP8B3, with 53% and 45% amino acid identity, respectively...
Scott L, Muglia P, Kong X, Guan W, Flickinger M, Upmanyu R, et al
. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci U S A. 2009;106:7501-6 pubmed publisher
..37, P = 0.042). Although these results are promising, analysis of additional samples will be required to confirm that variant(s) in these regions influence BP risk. ..