ATP5F1

Summary

Gene Symbol: ATP5F1
Description: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
Alias: PIG47, ATP synthase B chain, mitochondrial, ATP synthase subunit b, mitochondrial, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, ATPase subunit b, H+-ATP synthase subunit b, cell proliferation-inducing protein 47
Species: human

Top Publications

  1. pmc Two genes encoding the bovine mitochondrial ATP synthase proteolipid specify precursors with different import sequences and are expressed in a tissue-specific manner
    N J Gay
    EMBO J 4:3519-24. 1985
  2. doi Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss
    Yasuko Fujisawa
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Biochem J 423:219-31. 2009
  3. doi Selection of suitable reference genes for mRNA quantification studies using common marmoset tissues
    Yoshinori Shimamoto
    Department of Veterinary Teaching Hospital, School of Veterinary Medicine, Kitasato University, Towada, Aomori, 034 8628, Japan
    Mol Biol Rep 40:6747-55. 2013
  4. doi Low-intensity laser irradiation at 660 nm stimulates transcription of genes involved in the electron transport chain
    Roland T Masha
    Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, Johannesburg, South Africa
    Photomed Laser Surg 31:47-53. 2013
  5. doi Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance
    R J Li
    Department of Hematology Institute of Molecular Hematology, Second Xiang Ya Hospital, Central South University, Changsha, Hunan, China
    Ann Oncol 21:1506-14. 2010
  6. pmc Characterization of sINR, a strict version of the Initiator core promoter element
    Ganit Yarden
    Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 37:4234-46. 2009
  7. doi Comparative analysis of gene expression in brain, liver, skeletal muscles, and gills of zebrafish (Danio rerio) exposed to environmentally relevant waterborne uranium concentrations
    Adélaïde Lerebours
    Laboratoire de Radioecologie et d Ecotoxicologie, Institut de Radioprotection et de Surete Nucleaire, Bât 183, BP 3, 13115 Saint Paul lez Durance Cedex, France
    Environ Toxicol Chem 28:1271-8. 2009
  8. doi Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells
    Duck Woo Kim
    Department of Surgery, Seoul National University College of Medicine, Chongno Gu, Seoul, Korea
    Cancer Sci 99:1884-91. 2008
  9. pmc Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma
    Chun Feng Lee
    Institute of Molecular Medicine, National Tsing Hua University, Taiwan 30013, China
    World J Gastroenterol 14:6072-7. 2008
  10. ncbi Molecular motors: turning the ATP motor
    Richard L Cross
    Nature 427:407-8. 2004

Scientific Experts

  • Adélaïde Lerebours
  • Roland T Masha
  • Yoshinori Shimamoto
  • R J Li
  • Ganit Yarden
  • Yasuko Fujisawa
  • Duck Woo Kim
  • Chun Feng Lee
  • Richard L Cross
  • H Wang
  • Robert Aggeler
  • Libin Jia
  • Nicolette N Houreld
  • Mayumi Ishizuka
  • Fumio Hoshi
  • Heidi Abrahamse
  • Yasunaga Yoshikawa
  • Eiki Takahashi
  • Hiroshi Kitamura
  • Kimie Niimi
  • F J Gong
  • W Y Kuang
  • J F Zhu
  • Q J Lu
  • G S Zhang
  • Y H Chen
  • Kfir Gazit
  • Rivka Dikstein
  • Kazunobu Kato
  • Rofa Elfakess
  • Cecilia Giulivi
  • Young Kyoung Shin
  • Byong Chul Yoo
  • Sung Hye Hong
  • Jae Gahb Park
  • Zhi qiang Ling
  • Kuan Rong Lee
  • Kyung Hee Kim
  • Ting Zhao
  • Yong Chul Lim
  • G Oster
  • T Elston
  • John Powell
  • Robert Hotchkiss
  • Pamela Gehron Robey
  • Soumitra S Ghosh
  • Liming Yang
  • Jose J Garcia
  • Roderick A Capaldi
  • Michael F Marusich
  • Juliana Coons
  • Marian F Young
  • Steven W Taylor
  • Clair A Francomano
  • Nicola C Ho
  • J Houstek
  • P Tvrdik
  • U Andersson
  • B Cannon
  • J Nedergaard
  • T Higuti
  • L B Farrell
  • P D Boyer
  • N J Gay
  • W Momsen
  • Y Kawamura
  • H Tsujita
  • K Tanaka
  • J E Walker
  • I Tani
  • R L Cross
  • C Tsurumi
  • F Osaka
  • Y Yoshihara
  • P Nagley
  • A Ichihara

Detail Information

Publications18

  1. pmc Two genes encoding the bovine mitochondrial ATP synthase proteolipid specify precursors with different import sequences and are expressed in a tissue-specific manner
    N J Gay
    EMBO J 4:3519-24. 1985
    ..They are related to each other in regions which probably are recognition signals for the processing protease. The corresponding genes are expressed differently in various tissues in a way that reflects their embryonic origin...
  2. doi Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss
    Yasuko Fujisawa
    Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Biochem J 423:219-31. 2009
    ..Nitration at this residue would be more relevant under conditions of low nitrative stress. Conversely, at high nitrative stress conditions, both tyrosine residues would contribute equally to ATPase inactivation...
  3. doi Selection of suitable reference genes for mRNA quantification studies using common marmoset tissues
    Yoshinori Shimamoto
    Department of Veterinary Teaching Hospital, School of Veterinary Medicine, Kitasato University, Towada, Aomori, 034 8628, Japan
    Mol Biol Rep 40:6747-55. 2013
    ..In this study, we evaluated the expressions of 11 widely used reference genes: ACTB, ATP5F1, B2M, GAPDH, HPRT1, PGK1, PPIA, RN18S1, RPLP0, TBP and UBC in 12 tissues and five brain areas of healthy common ..
  4. doi Low-intensity laser irradiation at 660 nm stimulates transcription of genes involved in the electron transport chain
    Roland T Masha
    Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Doornfontein, Johannesburg, South Africa
    Photomed Laser Surg 31:47-53. 2013
    ..This study was undertaken to evaluate the effect of LILI on genes involved in the mitochondrial electron transport chain (ETC, complexes I-IV) and oxidative phosphorylation (ATP synthase)...
  5. doi Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance
    R J Li
    Department of Hematology Institute of Molecular Hematology, Second Xiang Ya Hospital, Central South University, Changsha, Hunan, China
    Ann Oncol 21:1506-14. 2010
    ..To identify novel proteins involved in multidrug resistance in chronic myeloid leukemia (CML)...
  6. pmc Characterization of sINR, a strict version of the Initiator core promoter element
    Ganit Yarden
    Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 37:4234-46. 2009
    ..Analysis of the sINR-containing DHX9 and ATP5F1 genes showed that the entire sINR sequence, including the strict core and the conserved flanking sequences, is ..
  7. doi Comparative analysis of gene expression in brain, liver, skeletal muscles, and gills of zebrafish (Danio rerio) exposed to environmentally relevant waterborne uranium concentrations
    Adélaïde Lerebours
    Laboratoire de Radioecologie et d Ecotoxicologie, Institut de Radioprotection et de Surete Nucleaire, Bât 183, BP 3, 13115 Saint Paul lez Durance Cedex, France
    Environ Toxicol Chem 28:1271-8. 2009
    ..Mitochondrial metabolism and DNA integrity also were affected, because coxI, atp5f1, and rad51 genes were up-regulated at day 21 and during the depuration phase...
  8. doi Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells
    Duck Woo Kim
    Department of Surgery, Seoul National University College of Medicine, Chongno Gu, Seoul, Korea
    Cancer Sci 99:1884-91. 2008
    ..In the presence of cell cycle synchronizing drugs, doxorubicin, etoposide, or nocodazole, suppression of galectin-3 induced cell cycle progression to G0/G1 phase...
  9. pmc Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma
    Chun Feng Lee
    Institute of Molecular Medicine, National Tsing Hua University, Taiwan 30013, China
    World J Gastroenterol 14:6072-7. 2008
    ....
  10. ncbi Molecular motors: turning the ATP motor
    Richard L Cross
    Nature 427:407-8. 2004
  11. ncbi A functionally active human F1F0 ATPase can be purified by immunocapture from heart tissue and fibroblast cell lines. Subunit structure and activity studies
    Robert Aggeler
    Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA
    J Biol Chem 277:33906-12. 2002
    ..The system is therefore suitable to screen patient-derived samples for alterations in amount or functionality of both the F(1)F(0) ATPase and IF(1)...
  12. ncbi Energy transduction in the F1 motor of ATP synthase
    H Wang
    Department of Molecular and Cellular Biology, College of Natural Resources, University of California, Berkeley 94720 3112, USA
    Nature 396:279-82. 1998
    ....
  13. ncbi Energy transduction in ATP synthase
    T Elston
    Department of Molecular and Cellular Biology, University of California, Berkeley 94720 3112, USA
    Nature 391:510-3. 1998
    ..Moreover, the motor's reversibility-supplying torque from ATP hydrolysis in F1 converts the motor into an efficient proton pump-can also be explained by our model...
  14. ncbi The expression of subunit c correlates with and thus may limit the biosynthesis of the mitochondrial F0F1-ATPase in brown adipose tissue
    J Houstek
    Institute of Physiology, Academy of Sciences of the Czech Republic, Prague
    J Biol Chem 270:7689-94. 1995
    ..An analogous regulatory role of the c-F0 subunit could be postulated in other tissues...
  15. pmc A new concept for energy coupling in oxidative phosphorylation based on a molecular explanation of the oxygen exchange reactions
    P D Boyer
    Proc Natl Acad Sci U S A 70:2837-9. 1973
    ..This release could logically involve energy-requiring protein conformational change...
  16. ncbi Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex
    L B Farrell
    Biochem Biophys Res Commun 144:1257-64. 1987
    ..Thus, as in bovine cells there appears to be at least two human genes encoding subunit 9...
  17. ncbi Molecular cloning of cDNA for the import precursor of human subunit B of H(+)-ATP synthase in mitochondria
    T Higuti
    Faculty of Pharmaceutical Sciences, University of Tokushima, Japan
    Biochem Biophys Res Commun 178:1014-20. 1991
    ..The presequence of 42 amino acids could be the import signal peptide for directing the protein into the mitochondrial matrix...
  18. ncbi Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis
    Libin Jia
    Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 79:7-17. 2002
    ..It is expected that high-throughput EST sequencing and data mining analysis will greatly promote our understanding of gene expression in these cells and of growth and development of the skeleton...