Gene Symbol: ARID1B
Description: AT-rich interaction domain 1B
Alias: 6A3-5, BAF250B, BRIGHT, CSS1, DAN15, ELD/OSA1, MRD12, OSA2, P250R, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, AT rich interactive domain 1B (SWI1-like), BRG1-associated factor 250b, BRG1-binding protein ELD/OSA1, ELD (eyelid)/OSA protein
Species: human
Products:     ARID1B

Top Publications

  1. Wang X, Nagl N, Wilsker D, Van Scoy M, Pacchione S, Yaciuk P, et al. Two related ARID family proteins are alternative subunits of human SWI/SNF complexes. Biochem J. 2004;383:319-25 pubmed
    ..b>ARID1B is an independent gene product with an open reading frame that is more than 60% identical with p270...
  2. Inoue H, Giannakopoulos S, Parkhurst C, Matsumura T, Kono E, Furukawa T, et al. Target genes of the largest human SWI/SNF complex subunit control cell growth. Biochem J. 2011;434:83-92 pubmed publisher
    ..BRG1-associated factor) chromatin-remodelling complex is encoded by two related cDNAs hOsa1/BAF250a and hOsa2/BAF250b that are unique to the BAF complex and absent in the related PBAF (Polybromo BAF)...
  3. Phelan M, Sif S, Narlikar G, Kingston R. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Mol Cell. 1999;3:247-53 pubmed
    ..The addition of INI1, BAF155, and BAF170 to BRG1 increases remodeling activity to a level comparable to that of the whole hSWI/SNF complex. These data define the functional core of the hSWI/SNF complex. ..
  4. Santen G, Aten E, Sun Y, Almomani R, Gilissen C, Nielsen M, et al. Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome. Nat Genet. 2012;44:379-80 pubmed publisher
    We identified de novo truncating mutations in ARID1B in three individuals with Coffin-Siris syndrome (CSS) by exome sequencing...
  5. Tsurusaki Y, Okamoto N, Ohashi H, Mizuno S, Makita Y, Fukuda M, et al. Coffin-Siris syndrome is a SWI/SNF complex disorder. Clin Genet. 2014;85:548-54 pubmed publisher
    ..non-fermenting (SWI/SNF) ATP-dependent chromatin-remodeling complex: SMARCB1, SMARCA4, SMARCE1, ARID1A, and ARID1B. In this study, we examined 49 newly recruited CSS-suspected patients, and re-examined three patients who did not ..
  6. Inoue H, Furukawa T, Giannakopoulos S, Zhou S, King D, Tanese N. Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors. J Biol Chem. 2002;277:41674-85 pubmed
    ..These results suggest that hOsa1 and hOsa2 participate in promoting transcriptional activation by the steroid hormone receptors. ..
  7. Nagl N, Wang X, Patsialou A, Van Scoy M, Moran E. Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. EMBO J. 2007;26:752-63 pubmed
    ..The specific complexes control access of factors such as E2F1, Tip60, and HDAC1/2/3 to the promoters of various cell-cycle-specific genes, with c-Myc emerging as a particularly critical target. ..
  8. Li X, Trojer P, Matsumura T, Treisman J, Tanese N. Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B. Mol Cell Biol. 2010;30:1673-88 pubmed publisher
    ..The characteristic member of human SWI/SNF-A is BAF250/ARID1, of which there are two isoforms, BAF250a/ARID1a and BAF250b/ARID1b...
  9. Sato C, Yamazawa T, Ohtani A, Maruyama Y, Memtily N, Sato M, et al. Primary cultured neuronal networks and type 2 diabetes model mouse fatty liver tissues in aqueous liquid observed by atmospheric SEM (ASEM): Staining preferences of metal solutions. Micron. 2019;118:9-21 pubmed publisher
    ..Swollen bright balls occupied a large area of the cytoplasm and could be distinguished from vacuoles, suggesting that they are ..

More Information

Publications144 found, 100 shown here

  1. Bartlett D, Willis L, Slentz C, Hoselton A, KELLY L, Huebner J, et al. Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study. Arthritis Res Ther. 2018;20:127 pubmed publisher
    ..002), with both nonclassical (CD14dim/CD16bright) and intermediate (CD14bright/CD16positive) monocytes being reduced (both p < 0...
  2. Liu F, Lin Q, Liu Z. A study on the role of apoptotic human umbilical cord mesenchymal stem cells in bleomycin-induced acute lung injury in rat models. Eur Rev Med Pharmacol Sci. 2016;20:969-82 pubmed
    ..Human umbilical cord mesenchymal stem cell transplantation may have a bright future in the clinical setting for the treatment of ALI/acute respiratory distress syndrome (ARDS)...
  3. Freyer L, Schroter C, Saiz N, Schrode N, Nowotschin S, Martinez Arias A, et al. A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice. BMC Dev Biol. 2015;15:38 pubmed publisher
    ..a Gata6(H2B-Venus) knock-in reporter mouse allele for the purpose of labeling GATA6-expressing cells with a bright nuclear-localized fluorescent marker that is suitable for live imaging at single-cell resolution...
  4. Landolt H, Holst S, Valomon A. Clinical and Experimental Human Sleep-Wake Pharmacogenetics. Handb Exp Pharmacol. 2018;: pubmed publisher
    ..Apart from behavioral (e.g., cognitive behavioral therapy for insomnia), physiological (e.g., chronotherapy with bright light), and mechanical (e.g...
  5. Scholz R, Sobotka M, Caramoy A, Stempfl T, Moehle C, Langmann T. Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration. J Neuroinflammation. 2015;12:209 pubmed publisher vitro and studied its immuno-modulatory properties in a mouse model of acute retinal degeneration using bright white light exposure...
  6. Huang Y, Yang M, Yu Y, Yang Y, Zhou L, Huang X, et al. Grouper TRIM13 exerts negative regulation of antiviral immune response against nodavirus. Fish Shellfish Immunol. 2016;55:106-15 pubmed publisher
    ..transfected cells, but the RING domain mutant resulted in the fluorescence distribution was changed and the bright punctate fluorescence was evenly situated throughout the cytoplasm, suggesting that the RING domain was essential ..
  7. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X, et al. Fish TRIM8 exerts antiviral roles through regulation of the proinflammatory factors and interferon signaling. Fish Shellfish Immunol. 2016;54:435-44 pubmed publisher
    ..EcTRIM8 in grouper spleen (GS) cells, including punctate fluorescence evenly situated throughout the cytoplasm and bright aggregates...
  8. Hasselbalch H, Holmström M. Perspectives on interferon-alpha in the treatment of polycythemia vera and related myeloproliferative neoplasms: minimal residual disease and cure?. Semin Immunopathol. 2019;41:5-19 pubmed publisher
    ..We envisage a new and bright future with many more patients with MPNs obtaining MRD on the above therapies...
  9. Xu C, Qiao L, Guo Y, Ma L, Cheng Y. Preparation, characteristics and antioxidant activity of polysaccharides and proteins-capped selenium nanoparticles synthesized by Lactobacillus casei ATCC 393. Carbohydr Polym. 2018;195:576-585 pubmed publisher
    ..Moreover, 50-80?nm SeNPs were accumulated in the intracellular L. casei 393. The whole bacteria present distinct bright red color...
  10. Watanabe T, Tan Z, Wang X, Martinez Hernandez A, Frahm J. Magnetic resonance imaging of noradrenergic neurons. Brain Struct Funct. 2019;: pubmed publisher
    ..mice lacking noradrenergic neurons confirms that cell bodies of noradrenergic neurons are the source of the bright MRI appearance...
  11. Tenório D, Andrade C, Cabral Filho P, Sabino C, Kato I, Carvalho L, et al. CdTe quantum dots conjugated to concanavalin A as potential fluorescent molecular probes for saccharides detection in Candida albicans. J Photochem Photobiol B. 2015;142:237-43 pubmed publisher
    ..microscopy images of yeasts and hyphae cells, as well as biofilms, incubated with QDs-(Con A) showed a bright orange fluorescence profile, indicating that the cell walls were specifically labeled...
  12. Lima M. Aggressive mature natural killer cell neoplasms: from epidemiology to diagnosis. Orphanet J Rare Dis. 2013;8:95 pubmed publisher
    ..The tumor cells have cytoplasmatic azurophilic granules and usually show a CD45(+bright), CD2(+), sCD3(-), cytCD3epsilon(+), CD56(+bright), CD16(−/+), cytotoxic granules molecules(+) phenotype...
  13. Ma X, Wang J, Wang J, Ma C, Wang X, Liu F. Malat1 as an evolutionarily conserved lncRNA, plays a positive role in regulating proliferation and maintaining undifferentiated status of early-stage hematopoietic cells. BMC Genomics. 2015;16:676 pubmed publisher
    ..progenitor cells show a high level of Malat1 expression, while LRB (Lin - Hoechst(Low) Rhodamine(Bright)) cells that represent the late-stage progenitor cells had no detectable expression of Malat1...
  14. Jennes M, De Craeye S, Devriendt B, Dierick K, Dorny P, Cox E. Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8+ Lymphocytes in a Heterologous Challenge Model. Front Cell Infect Microbiol. 2017;7:232 pubmed publisher
    ..correlated with the infection dose and predominantly brought about by CD3+CD4-CD8αbright T-lymphocytes...
  15. Biswas M, Mano J. Lipid Peroxide-Derived Short-Chain Carbonyls Mediate Hydrogen Peroxide-Induced and Salt-Induced Programmed Cell Death in Plants. Plant Physiol. 2015;168:885-98 pubmed publisher
    ..Here, we investigated how oxylipin carbonyls cause cell death. When tobacco (Nicotiana tabacum) Bright Yellow-2 (BY-2) cells were exposed to hydrogen peroxide, several species of short-chain oxylipin carbonyls [i.e...
  16. Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang S, et al. Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells. Blood. 2017;129:1927-1939 pubmed publisher
    ..GATA-2) was expressed in hematopoietic stem cells, but not in NK-cell progenitors, CD3-CD56bright, canonical, or adaptive CD3-CD56dim NK cells...
  17. Vezzalini M, Mafficini A, Tomasello L, Lorenzetto E, Moratti E, Fiorini Z, et al. A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients. J Hematol Oncol. 2017;10:129 pubmed publisher
    ..downregulation at diagnosis in the Philadelphia-positive myeloid lineage (including CD34+/CD38bright/dim cells)...
  18. Kim Y, Griffin J, Nor M, Zhang J, Freestone P, Danesh Meyer H, et al. Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels. Neurotherapeutics. 2017;14:1148-1165 pubmed publisher
    ..Systemic delivery of tonabersat in a rat bright-light retinal damage model (a model for dry age-related macular degeneration) resulted in significantly improved ..
  19. Tsai K, Cherng J, Liu Y, Chen T, Wong H, Yang S, et al. Cinnamomum verum component 2-methoxycinnamaldehyde: a novel antiproliferative drug inducing cell death through targeting both topoisomerase I and II in human colorectal adenocarcinoma COLO 205 cells. Food Nutr Res. 2016;60:31607 pubmed publisher
    ..was evaluated by colorimetric assay; apoptosis was determined by flow cytometry and morphological analysis with bright field, acridine orange, and neutral red stainings, as well as comet assay; topoisomerase I activity was determined ..
  20. Julhakyan H, Al Radi L, Moiseeva T, Danishyan K, Kovrigina A, Glebova S, et al. A Single-center Experience in Splenic Diffuse Red Pulp Lymphoma Diagnosis. Clin Lymphoma Myeloma Leuk. 2016;16 Suppl:S166-9 pubmed publisher
    ..000 and 75.000 109/l). The circulating "villous" lymphocytes phenotype was CD20+ (bright), CD11c+/±, CD103 (weakly)+/±, LAIR-1+, CD25-, CD5-, CD10-, and CD23-. Mutation BRAFV600E was not detected...
  21. Malerba M, Cerana R. Effect of Selenium on the Responses Induced by Heat Stress in Plant Cell Cultures. Plants (Basel). 2018;7: pubmed publisher
    ..Previous results showed that in tobacco (Nicotiana tabacum cv. Bright-Yellow 2) cultures HS (5 min at 50 °C) induced cell death with apoptotic features, accompanied by oxidative ..
  22. Hao P. Monitoring of renal ischemia reperfusion injury in rabbits by ultrasonic contrast and its relationship with expression of VEGF in renal tissue. Asian Pac J Trop Med. 2016;9:188-92 pubmed publisher
    ..Because of the tissue ischemia, it could be seen that the color of kidney was changed from bright red to dark red, which indicated the successful modeling of ischemia...
  23. Gao Q, Yellapantula V, Fenelus M, Pichardo J, Wang L, Landgren O, et al. Tumor suppressor CD99 is downregulated in plasma cell neoplasms lacking CCND1 translocation and distinguishes neoplastic from normal plasma cells and B-cell lymphomas with plasmacytic differentiation from primary plasma cell neoplasms. Mod Pathol. 2018;31:881-889 pubmed publisher
    ..In contrast to the uniform bright expression on normal plasma cells, CD99 expression on neoplastic plasma cells was lost in 39 out of 56 (69...
  24. Sokol E, Miller D, Breggia A, Spencer K, Arendt L, Gupta P. Growth of human breast tissues from patient cells in 3D hydrogel scaffolds. Breast Cancer Res. 2016;18:19 pubmed publisher
    ..Tissue growth was monitored over time using bright-field and fluorescence microscopy, and maturation was assessed using morphological metrics and by immunostaining ..
  25. Robertson R, Levine S, Haynes S, Gutierrez P, Baratta J, Tan Z, et al. Use of labeled tomato lectin for imaging vasculature structures. Histochem Cell Biol. 2015;143:225-34 pubmed publisher
    ..Tissue labeled by biotinylated lectin was examined by bright field microscopy or electron microscopy after tissue processing for biotin...
  26. Nowak I, Wilczyńska K, Wilczynski J, Malinowski A, Radwan P, Radwan M, et al. KIR, LILRB and their Ligands' Genes as Potential Biomarkers in Recurrent Implantation Failure. Arch Immunol Ther Exp (Warsz). 2017;65:391-399 pubmed publisher
    ..The majority of these cells are of CD56bright phenotype...
  27. Cao Y, Du J, Chen D, Wang Q, Zhang N, Liu X, et al. RNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes. Cell Cycle. 2016;15:2608-2618 pubmed
    ..The majority oocytes were arrested at MI stage, with bright MAD1 at kinetochores, indicating activation of spindle assembly checkpoint (SAC)...
  28. Bista R, Lee D, Pepper O, Azorsa D, Arceci R, Aleem E. Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells. J Exp Clin Cancer Res. 2017;36:22 pubmed publisher
    ..The Ara-C-resistant DS-AMKL CMY cells had a high percentage of ALDHbright "stem-like" populations that may underlie Ara-C resistance...
  29. Byun Y, Chung W. A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes. J Vis Exp. 2018;: pubmed publisher
    ..detection of engulfment and degradation is possible using pH indicator-conjugated synaptosomes, which emit bright red fluorescence in acidic organelles, such as lysosomes...
  30. Eshaghi M, Sun G, Grüter A, Lim C, Chee Y, Jung G, et al. Rational Structure-Based Design of Bright GFP-Based Complexes with Tunable Dimerization. Angew Chem Int Ed Engl. 2015;54:13952-6 pubmed publisher
    ..The vGFP strategy thus allows upgrading of existing applications, is applicable to other fluorescent proteins, and suggests a method for tuning dimerization of arbitrary proteins and optimizing protein properties in general. ..
  31. Wu F, Yuan H, Zhou C, Mao M, Liu Q, Shen H, et al. Multiplexed detection of influenza A virus subtype H5 and H9 via quantum dot-based immunoassay. Biosens Bioelectron. 2016;77:464-70 pubmed publisher
    ..This complex produced a bright fluorescent band in response to 365 nm ultraviolet excitation...
  32. Kim Y, Pennycook S, Borisevich A. Quantitative comparison of bright field and annular bright field imaging modes for characterization of oxygen octahedral tilts. Ultramicroscopy. 2017;181:1-7 pubmed publisher
    ..two major approaches for quantitative imaging of tilts in scanning transmission electron microscopy (STEM), bright field (BF) and annular bright field (ABF)...
  33. Ahn J, Ahn S, Yang K, Kim S, Oh J. Effects of a high level of illumination before sleep at night on chorioretinal thickness and ocular biometry. Exp Eye Res. 2017;164:157-167 pubmed publisher
    ..However, the effects of bright light before sleep at night on the human eye are not well established...
  34. Tullius R, Platt G, Khosravi Khorashad L, Gadegaard N, Lapthorn A, Rotello V, et al. Superchiral Plasmonic Phase Sensitivity for Fingerprinting of Protein Interface Structure. ACS Nano. 2017;: pubmed publisher
    ..interaction of proteins with superchiral fields induces asymmetric changes in retardation phase effects of excited bright and dark modes of a chiral plasmonic nanostructure...
  35. Yao X, Meng Q, Li G. RNA interference-mediated functional characterization of aquaporin genes in Tribolium castaneum. Insect Mol Biol. 2017;: pubmed publisher
    ..RNA interference (RNAi)-mediated knockdown of TcEglp3 caused a grey larval cuticle, in contrast to a smooth and bright cuticle in control larvae...
  36. Rizzo S, Belting C, Cinelli L, Allegrini L, Genovesi Ebert F, Barca F, et al. The Argus II Retinal Prosthesis: 12-month outcomes from a single-study center. Am J Ophthalmol. 2014;157:1282-90 pubmed publisher
    ..Wound dehiscence, endophthalmitis or retinal detachment was not observed. All patients were able to locate a bright light on the ceiling and a dark line on the floor after the surgery...
  37. Kudek M, Shanley R, Zantek N, McKenna D, Smith A, Miller W. Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Nonmalignant Disease. Biol Blood Marrow Transplant. 2016;22:2019-2024 pubmed publisher
    ..Because the future for umbilical cord blood (UCB) expansion technologies is bright, we assessed whether this typically overlooked graft characteristic impacted various outcomes after UCB ..
  38. Kaczmarek A, Porebski P, Mortier T, Lynen F, Van Deun R, Van Hecke K. Near-infrared luminescence and RNA cleavage ability of lanthanide Schiff base complexes derived from N,N'-bis(3-methoxysalicylidene)ethylene-1,2-diamine ligands. J Inorg Biochem. 2016;163:194-205 pubmed publisher
    ..A detailed luminescence study was additionally carried out and revealed that the Eu3+ complex emitted bright red light upon excitation at both 285.8nm and 394.4nm...
  39. Tyler C, Likova L. Studying the Retinal Source of Photophobia by Facial Electroretinography. Optom Vis Sci. 2017;94:511-518 pubmed publisher
    Photophobia is a debilitating clinical condition that disrupts the ability to use vision for everyday tasks in bright lighting conditions...
  40. Jeong J, Kim H, Lee D, Jung B, Lee J. RCA-Based Biosensor for Electrical and Colorimetric Detection of Pathogen DNA. Nanoscale Res Lett. 2016;11:242 pubmed publisher
    ..existence of the target DNA was readily detected by the naked eyes through change in colors of the electrodes from bright yellow to orange-red after RCA reaction...
  41. Liu R, Tao L, Liu B, Tian X, Mohammad M, Yang Y, et al. A Miniaturized On-Chip Colorimeter for Detecting NPK Elements. Sensors (Basel). 2016;16: pubmed publisher
    ..All these advantages enable a low-cost and high-precision sensing operation in a monitoring network. The colorimeter developed herein has bright prospects for environmental and biological applications.
  42. Shin I, An C, Lim J, Kim M, Chung Y. T1 bright appendix sign to exclude acute appendicitis in pregnant women. Eur Radiol. 2017;27:3310-3316 pubmed publisher
    To evaluate the diagnostic value of the T1 bright appendix sign for the diagnosis of acute appendicitis in pregnant women...
  43. Suzuki M, Udaka H, Fukuda T. Quantum dot-linked immunosorbent assay (QLISA) using orientation-directed antibodies. J Pharm Biomed Anal. 2017;143:110-115 pubmed publisher
    ..In this study, CdSe/ZnS quantum dots are introduced as bright and photobleaching-tolerant fluorescent materials...
  44. Nalla V, Valente J, Sun H, Zheludev N. 11-fs dark pulses generated via coherent absorption in plasmonic metamaterial. Opt Express. 2017;25:22620-22625 pubmed publisher
    ..of our approach in comparison with previously developed laser sources of dark pulses is that, in principle, it allows transferring arbitrary pattern of bright pulses into a pattern of dark pulses in another optical signal channel.
  45. Sexton T, Bleckert A, Turner M, Van Gelder R. Type I intrinsically photosensitive retinal ganglion cells of early post-natal development correspond to the M4 subtype. Neural Dev. 2015;10:17 pubmed publisher
    ..We now show that Type I cells show have rapid and robust recovery from long and short bright light exposures compared with Type II and III cells, suggesting differential light adaptation mechanisms between ..
  46. Kawai M, Goda R, Otsuka T, Iwamoto A, Uotsu N, Furuse M, et al. Antidepressant-like effect of bright light is potentiated by L-serine administration in a mouse model of seasonal affective disorder. Brain Res Bull. 2015;118:25-33 pubmed publisher
    b>Bright light therapy is used as the primary treatment for seasonal affective disorder; however, the mechanisms underlying its antidepressant effect are not fully understood...
  47. Tsukamoto M, Seta N, Yoshimoto K, Suzuki K, Yamaoka K, Takeuchi T. CD14brightCD16+ intermediate monocytes are induced by interleukin-10 and positively correlate with disease activity in rheumatoid arthritis. Arthritis Res Ther. 2017;19:28 pubmed publisher
    Three different subsets of circulating human monocytes, CD14brightCD16- (classical), CD14brightCD16+ (intermediate), and CD14dimCD16+ (non-classical) have been recently identified...
  48. Wan H, Yue J, Zhu S, Uno T, Zhang X, Yang Q, et al. A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues. Nat Commun. 2018;9:1171 pubmed publisher
    ..Here we develop a bright organic nanofluorophore (named p-FE) for high-performance biological imaging in the NIR-II window...
  49. Ford K, Baumgartner K, Henricot B, Bailey A, Foster G. A reliable in vitro fruiting system for Armillaria mellea for evaluation of Agrobacterium tumefaciens transformation vectors. Fungal Biol. 2015;119:859-869 pubmed publisher
    ..Following medium colonisation for 4 weeks, cultures were incubated under warm/bright conditions for 4-6 weeks before incubation in dim/cool conditions...
  50. Jeong J, Baek K, Kirst H, Melis A, Jin E. Loss of CpSRP54 function leads to a truncated light-harvesting antenna size in Chlamydomonas reinhardtii. Biochim Biophys Acta Bioenerg. 2017;1858:45-55 pubmed publisher microalgae can serve to generate tla mutants with a markedly smaller photosystem Chl antenna size, improved solar energy conversion efficiency, and photosynthetic productivity in high-density cultures under bright sunlight conditions.
  51. Pode Shakked N, Gershon R, Tam G, Omer D, Gnatek Y, Kanter I, et al. Evidence of In Vitro Preservation of Human Nephrogenesis at the Single-Cell Level. Stem Cell Reports. 2017;9:279-291 pubmed publisher
    ..NCAM+/CD133-/EpCAMdim, NCAM+/CD133-/EpCAMbright), we show at single-cell resolution a preservation of uninduced and induced cap mesenchyme as well as a ..
  52. Min J, Nayak J, Hulse K, Stevens W, Raju P, Huang J, et al. Evidence for altered levels of IgD in the nasal airway mucosa of patients with chronic rhinosinusitis. J Allergy Clin Immunol. 2017;140:1562-1571.e5 pubmed publisher
    ..We also found that IgD+CD19+CD38bright plasmablast numbers were significantly increased in tissues from patients with CRSsNP compared with control ..
  53. Letelier J, Bovolenta P, Martínez Morales J. The pigmented epithelium, a bright partner against photoreceptor degeneration. J Neurogenet. 2017;:1-13 pubmed publisher
  54. Penna Martinez M, Filmann N, Bogdanou D, Shoghi F, Huenecke S, Schubert R, et al. High-dose vitamin D in Addison's disease regulates T-cells and monocytes: A pilot trial. Nutrition. 2018;49:66-73 pubmed publisher
    ..CD3+CD4+HLA-DR+), regulatory T cells (CD3+CD4+CD25brightCD127dim/neg), cytotoxic T cells (Tc; CD3+CD8+), late-activated Tc cells (..
  55. Sweeney N, Nahas S, Chowdhury S, del Campo M, Jones M, Dimmock D, et al. The case for early use of rapid whole genome sequencing in management of critically ill infants: Late diagnosis of Coffin-Siris syndrome in an infant with left congenital diaphragmatic hernia, congenital heart disease and recurrent infections. Cold Spring Harb Mol Case Stud. 2018;: pubmed publisher
    ..3096_3100delCAAAG (p.Lys1033Argfs*32) variant in ARID1B, providing a diagnosis of Coffin-Siris syndrome. Her parents elected palliative care and she died later that day...
  56. Geng J, Goh C, Qin W, Liu R, Tomczak N, Ng L, et al. Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging. Chem Commun (Camb). 2015;51:13416-9 pubmed publisher
    ..The co-pretected NPs show bright red fluorescence (50% quantum yield) with a large two-photon action cross-section (450 GM at 840 nm), which have ..
  57. Zheng S, Xie R, Guan R, Guo J. [Amount Change of Peripheral Blood NK Cells in Patients with Hematologic Malignancies and Its Clinical Significance]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2015;23:1133-7 pubmed publisher
    ..05). In control group, the number of CD56(bright) subgroup was (25.28 ± 4.72) %, the number of CD56(bright) subgroup at the acute stage of leukemia was (65...
  58. Huang Y, Zhang J, Liu J, Hu Y, Ni S, Yang Y, et al. Fish TRIM35 negatively regulates the interferon signaling pathway in response to grouper nodavirus infection. Fish Shellfish Immunol. 2017;69:142-152 pubmed publisher
    ..Under fluorescence microscopy, the bright fluorescence aggregates were observed in EcTRIM35 transfected cells, but the fluorescence distribution was ..
  59. Li X, Liu R, Shi T, Dong S, Ren F, Yang F, et al. Primary pulmonary malignant fibrous histiocytoma: case report and literature review. J Thorac Dis. 2017;9:E702-E708 pubmed publisher
    ..Five gene mutations in TSC2, ARID1B, CDK8, KDM5C and CASP8 were detected, and the mTOR inhibitor might be an effective treatment for this patient...
  60. Zhang S, Dong Y, Fu H, Huang S, Zhang L. A Spectral Reconstruction Algorithm of Miniature Spectrometer Based on Sparse Optimization and Dictionary Learning. Sensors (Basel). 2018;18: pubmed publisher
    ..As for the non-directly sparse spectra, their sparsity can be enhanced by dictionary learning. In conclusion, the proposed approach has a bright application prospect in fabricating a practical miniature spectrometer.
  61. Ye L, Huang Y, Dai F, Ning H, Li C, Zhou M, et al. Identification of two key genes controlling chill haze stability of beer in barley (Hordeum vulgare L). BMC Genomics. 2015;16:449 pubmed publisher
    In bright beer, haze formation is a serious quality problem, degrading beer quality and reducing its shelf life...
  62. Wang F, Chen M, Yan Y, Zhaoping L, Li W. Modulation of Neuronal Responses by Exogenous Attention in Macaque Primary Visual Cortex. J Neurosci. 2015;35:13419-29 pubmed publisher
    ..A bright annular cue was flashed either around the receptive fields of recorded neurons or in the opposite visual field to ..
  63. Hatano K, Sugimura K, Crocetti E. Looking at the dark and bright sides of identity formation: New insights from adolescents and emerging adults in Japan. J Adolesc. 2016;47:156-68 pubmed publisher
    The aim of the present study was to gain new insights into the dark and bright sides of identity formation with a sample of 1851 Japanese adolescents and emerging adults, applying a three-dimensional model of identity formation (i.e...
  64. McCuen Wurst C, Ruggieri M, Allison K. Disordered eating and obesity: associations between binge-eating disorder, night-eating syndrome, and weight-related comorbidities. Ann N Y Acad Sci. 2017;: pubmed publisher
    ..including cognitive behavior therapy (CBT), interpersonal psychotherapy, lisdexamfetamine, and selective serotonin reuptake inhibitors (SSRIs) for BED; and CBT, SSRIs, progressive muscle relaxation, and bright light therapy for NES.
  65. Liu S, Yang M, Liu Y, Chen H, Li H. A novel "turn-on" fluorescent probe based on triphenylimidazole-hemicyanine dyad for colorimetric detection of CN- in 100% aqueous solution. J Hazard Mater. 2018;344:875-882 pubmed publisher
    ..from orange to light pink in the sunlight as well as an obvious fluorescence color change from non-emissive to bright blue under a UV lamp. The detection limit of CN- in aqueous solution can be as low as 20...
  66. Rey F, Stiasny K, Vaney M, Dellarole M, Heinz F. The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design. EMBO Rep. 2018;19:206-224 pubmed publisher
    ..We end by proposing a strategy for developing an epitope-focused vaccine approach to avoid eliciting undesirable antibodies while focusing the immune system on producing protective antibodies only. ..
  67. da Silva Jñnior M, de Fz Lizarelli R, Bagnato V, Tonetto M, Simões F, Borges A, et al. Effect of the Curing Temperature of Dental Composites evaluated with a Fluorescent Dye. J Contemp Dent Pract. 2018;19:3-12 pubmed
    ..Gnatus Optilight Digital (halogen) and two LEDs that use a new technology to assembly the diodes: LEC 1000 and bright LEC (MM Optics) (LED 1 and LED 2 respectively)...
  68. Zhang F, Feng X, Zhang Y, Yan L, Yang Y, Liu X. Photoluminescent carbon quantum dots as a directly film-forming phosphor towards white LEDs. Nanoscale. 2016;8:8618-32 pubmed publisher
    ..The optical properties of the as-obtained CQDs were investigated in detail. The CQD aqueous solution emits bright blue-white light under ultraviolet (UV) illumination with a quantum yield of 57...
  69. Krebs M, Xiao M, Sheppard K, Hicks W, Nishina P. Bright-Field Imaging and Optical Coherence Tomography of the Mouse Posterior Eye. Methods Mol Biol. 2016;1438:395-415 pubmed publisher
    Noninvasive live imaging has been used extensively for ocular phenotyping in mouse vision research. Bright-field imaging and optical coherence tomography (OCT) are two methods that are particularly useful for assessing the posterior mouse ..
  70. Oppermann D, Schramme J, Neumeyer C. Rod-cone based color vision in seals under photopic conditions. Vision Res. 2016;125:30-40 pubmed publisher
    ..The results show that the animals could see the colored triangle despite minimal or zero brightness contrast. Thus, seals have color vision based on the contribution of cones and rods even in bright daylight.
  71. Engelen W, van de Wiel K, Meijer L, Saha B, Merkx M. Nucleic acid detection using BRET-beacons based on bioluminescent protein-DNA hybrids. Chem Commun (Camb). 2017;53:2862-2865 pubmed publisher
    ..Bioluminescent molecular beacons have been developed using a modular design approach that relies on BRET between the bright luciferase NanoLuc and a Cy3 acceptor...
  72. Minoda H, Tamai T, Ohmori Y, Iijima H. Contrast enhancement of nanomaterials using phase plate STEM. Ultramicroscopy. 2017;182:163-168 pubmed publisher
    ..The PCTF for P-STEM with a spatial frequency below 1 nm-1 is about three times stronger than that of bright field STEM...
  73. Brigo F, Lattanzi S, Trinka E, Nardone R, Bragazzi N, Ruggieri M, et al. 'Infantile convulsions' in the early nineteenth century. Abnormal brain blood flow and leeches, teething and gums' scarification and food and purgatives: the historical contribution of John Clarke (1760-1815). Childs Nerv Syst. 2018;34:1271-1278 pubmed publisher
    ..that could trigger convulsions, including bad digestion (more pronounced at the time of teething), loud noise, and bright light...
  74. Daniels R, Culham S, Hunter M, Durrant M, Probert M, Clegg W, et al. When two are better than one: bright phosphorescence from non-stereogenic dinuclear iridium(III) complexes. Dalton Trans. 2016;45:6949-62 pubmed publisher
  75. Shcherbakova D, Baloban M, Emelyanov A, Brenowitz M, Guo P, Verkhusha V. Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging. Nat Commun. 2016;7:12405 pubmed publisher
    ..We report three bright and spectrally distinct monomeric NIR FPs, termed miRFPs, engineered from bacterial phytochrome, which can be used ..
  76. Pushkarev A, Balashova T, Kukinov A, Arsenyev M, Yablonskiy A, Kryzhkov D, et al. Sensitization of NIR luminescence of Yb3+ by Zn2+ chromophores in heterometallic complexes with a bridging Schiff-base ligand. Dalton Trans. 2017;46:10408-10417 pubmed publisher
    ..The compounds 1-4 were structurally characterized. The ytterbium derivatives 2-4 exhibited bright NIR metal-centred photoluminescence (PL) of Yb3+ ion under one- (λex = 380 nm) and two-..
  77. Huang J, Zhou J, Zhuang J, Gao H, Huang D, Wang L, et al. Strong Near-Infrared Absorbing and Biocompatible CuS Nanoparticles for Rapid and Efficient Photothermal Ablation of Gram-Positive and -Negative Bacteria. ACS Appl Mater Interfaces. 2017;9:36606-36614 pubmed publisher
    ..68%), the BSA-CuS nanocomposites combined with NIR irradiation will shed bright light on the treatment of antibiotic-resistant pathogenic bacteria.
  78. Ricciardi M. Principles and applications of the balanced steady-state free precession sequence in small animal low-field MRI. Vet Res Commun. 2018;42:65-86 pubmed publisher the ratio of T2 and T1, resulting in low soft-tissue signal, poor cerebral grey/white matter distinction and a bright signal from free fluid and fat...
  79. Zhai Y, Shim M. Benefitting from Dopant Loss and Ostwald Ripening in Mn Doping of II-VI Semiconductor Nanocrystals. Nanoscale Res Lett. 2015;10:423 pubmed publisher
    ..These results provide an improved understanding of the doping process in a simple and potentially scalable synthetic strategy for achieving "pure" and bright dopant emission.
  80. Wadhwani S, Shedbalkar U, Singh R, Chopade B. Biogenic selenium nanoparticles: current status and future prospects. Appl Microbiol Biotechnol. 2016;100:2555-66 pubmed publisher
    ..They can be synthesized by physical, chemical, and biological methods and have distinct bright orange-red color. Biogenic SeNPs are stable and do not aggregate owing to natural coating of the biomolecules...
  81. Yu Y, Liang C, Lv Q, Li D, Xu X, Liu B, et al. Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers. Int J Mol Sci. 2016;17:358 pubmed publisher
    ..stages of clinical evaluation for various disease therapies including macular degeneration, cancer, inflammation and coagulation to highlight the bright commercial future and potential challenges of therapeutic oligonucleotide aptamers.
  82. Johansen V, Catón L, Hamidjaja R, Oosterink E, Wilts B, Rasmussen T, et al. Genetic manipulation of structural color in bacterial colonies. Proc Natl Acad Sci U S A. 2018;115:2652-2657 pubmed publisher
    Naturally occurring photonic structures are responsible for the bright and vivid coloration in a large variety of living organisms...
  83. Bernatchez M, Savard J, Ivers H. Disruptions in sleep-wake cycles in community-dwelling cancer patients receiving palliative care and their correlates. Chronobiol Int. 2017;:1-14 pubmed publisher
    ..Effective non-pharmacological interventions are needed to improve patients' circadian rhythms, including perhaps bright light therapy.
  84. Fitter S, Gronthos S, Ooi S, Zannettino A. The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70. Stem Cells. 2017;35:940-951 pubmed publisher
    ..with heat shock protein 70 (HSP70), however all the clonogenic cell activity is restricted to the STRO-1BRIGHT /HSP70- fraction...
  85. Wang L, Huang J, Chen H, Wu H, Xu Y, Li Y, et al. Exerting Enhanced Permeability and Retention Effect Driven Delivery by Ultrafine Iron Oxide Nanoparticles with T1-T2 Switchable Magnetic Resonance Imaging Contrast. ACS Nano. 2017;11:4582-4592 pubmed publisher
    ..Moreover, in vivo magnetic resonance imaging revealed that uIONPs exhibited "bright" T1 contrast when dispersed in the tumor vasculature and peripheral area at 1 h after intravenous ..
  86. Hurlstone A, Olave I, Barker N, van Noort M, Clevers H. Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein. Biochem J. 2002;364:255-64 pubmed
    ..EHD1 and EHD2 also appear capable of interacting with each other. Using an antibody raised against EHD2 of hELD/OSA1, we detected Eld/Osa1 in endogenous SWI/SNF complexes derived from mouse brain. ..
  87. Leahy L. Overcoming Seasonal Affective Disorder. J Psychosoc Nurs Ment Health Serv. 2017;55:10-14 pubmed publisher
    ..after reading the article, nurses of all disciplines will have a better understanding of the evidence-based bright light therapy (also known as light box therapy) and how to incorporate this treatment when caring for patients ..
  88. Castillo J, Treon S. Toward personalized treatment in Waldenström macroglobulinemia. Hematology Am Soc Hematol Educ Program. 2017;2017:365-370 pubmed publisher
    ..Finally, we propose a genomically driven algorithm for the treatment of WM. The future of therapies for WM appears bright and hopeful, but we should be mindful of the cost-effectiveness and long-term toxicity of novel agents.
  89. Zhang Y, Sheng W, Li Y. Dark excitons and tunable optical gap in graphene nanodots. Phys Chem Chem Phys. 2017;19:23131-23137 pubmed publisher
    ..The first excited state in most of the cases is found to be a dark singlet; however, the order of dark and bright excitonic states is shown to be quite sensitive to the strength of electron-electron interactions such as the ..
  90. Konwar M, Laven P, Prabha T. Simultaneous observation of a glory and in-situ microphysical cloud properties. Appl Opt. 2017;56:G5-G8 pubmed publisher
    While making airborne measurements of cloud particles, a bright glory was observed on a thin layer cloud. By deliberately flying through this glory-producing cloud on several occasions, cloud particle size distributions were obtained...
  91. Yang W, Shi S, Wang Y, Ma W, Zheng Y, Peng K. Detection of stably bright squeezed light with the quantum noise reduction of 12.6??dB by mutually compensating the phase fluctuations. Opt Lett. 2017;42:4553-4556 pubmed publisher
    ..fluctuations, originating from the residual amplitude modulation (RAM) in the phase modulation process, in the bright squeezed light generation system...
  92. Wu L, Amidi A, Valdimarsdottir H, Ancoli Israel S, Liu L, Winkel G, et al. The Effect of Systematic Light Exposure on Sleep in a Mixed Group of Fatigued Cancer Survivors. J Clin Sleep Med. 2017;: pubmed
    Sleep disturbances are commonly reported by cancer survivors. Systematic light exposure using bright light has been used to improve sleep in other populations...