ARCN1

Summary

Gene Symbol: ARCN1
Description: archain 1
Alias: COPD, SRMMD, coatomer subunit delta, archain vesicle transport protein 1, coatomer delta subunit, coatomer protein complex, subunit delta, coatomer protein delta-COP, delta-COP, delta-coat protein
Species: human
Products:     ARCN1

Top Publications

  1. Perugi G, Quaranta G, Belletti S, Casalini F, Mosti N, Toni C, et al. General medical conditions in 347 bipolar disorder patients: clinical correlates of metabolic and autoimmune-allergic diseases. J Affect Disord. 2015;170:95-103 pubmed publisher
    ..Psoriasis, Seborrheic Dermatitis, Diabetes Mellitus, Bronchial Asthma, Cardiac Arrhythmias, Biliary Lithiasis, and COPD. In our sample, MD (n=148, 42.7%) and AAD (n=167, 48.1%) were the most common categories of GMCs...
  2. Abaza H, Marschollek M. mHealth Application Areas and Technology Combinations*. A Comparison of Literature from High and Low/Middle Income Countries. Methods Inf Med. 2017;56:e105-e122 pubmed publisher
    ..n=7), cancer (n=5), family health planning (n=5), TB (n=3), malaria (n=2), chronic obtrusive pulmonary disease (COPD) (n=2), vision care (n=2), and dermatology (n=2)...
  3. Jernigan N, Resta T, Gonzalez Bosc L. Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension. Adv Exp Med Biol. 2017;967:83-103 pubmed publisher
    ..hypoxia is a critical pathological factor associated with the development of PH resulting from airway obstruction (COPD, sleep apnea), diffusion impairment (interstitial lung disease), developmental lung abnormalities, or high altitude ..
  4. Wang Z, Li R, Zhong R. Extracellular matrix promotes proliferation, migration and adhesion of airway smooth muscle cells in a rat model of chronic obstructive pulmonary disease via upregulation of the PI3K/AKT signaling pathway. Mol Med Rep. 2018;18:3143-3152 pubmed publisher
    ..the tissue microenvironment and serves a role in airway wall remodeling in chronic obstructive pulmonary disease (COPD). However, the biological function of ECM in COPD remains to be elucidated...
  5. Yadav U, Ramana K, Srivastava S. Aldose reductase regulates acrolein-induced cytotoxicity in human small airway epithelial cells. Free Radic Biol Med. 2013;65:15-25 pubmed publisher
    ..and cigarette smoke, is known to be involved in various pathologies including atherosclerosis, airway inflammation, COPD, and age-related disorders, but the mechanism of acrolein-induced cytotoxicity is not clearly understood...
  6. Waschki B, Watz H, Holz O, Magnussen H, Olejnicka B, Welte T, et al. Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function. Int J Chron Obstruct Pulmon Dis. 2017;12:981-987 pubmed publisher
    ..dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). The role of PAI-1 in COPD with respect to metabolic and cardiovascular functions is unclear...
  7. Macedo Viñas M, Denning D. Estimating the Burden of Serious Fungal Infections in Uruguay. J Fungi (Basel). 2018;4: pubmed publisher
    ..12,000; acute myeloid leukemia 126; hematopoietic stem cell transplantation 30; solid organ transplants 134; COPD 272,006; asthma in adults 223,431; cystic fibrosis in adults 48; tuberculosis 613; lung cancer 1400...
  8. Hurraß J, Heinzow B, Aurbach U, Bergmann K, Bufe A, Buzina W, et al. Medical diagnostics for indoor mold exposure. Int J Hyg Environ Health. 2017;220:305-328 pubmed publisher
    ..Inadequate or insufficient evidence for an association is given for COPD, acute idiopathic pulmonary hemorrhage in children, rheumatism/arthritis, sarcoidosis, and cancer...
  9. Ortega R, Jiménez Ortega A, Perea Sánchez J, Cuadrado Soto E, Martínez García R, López Sobaler A. Oral feeding and nutritional improvement in hospitals and residential care homes. Industry innovations. Nutr Hosp. 2017;34:13-18 pubmed publisher
    ..cataract disease, COPD, cognitive impairment and less defense against infections...

More Information

Publications159 found, 100 shown here

  1. Zhang X, Xiang S, Geng W, Cong W, Lu J, Jiang C, et al. Electro-acupuncture regulates the cholinergic anti-inflammatory pathway in a rat model of chronic obstructive pulmonary disease. J Integr Med. 2018;16:418-426 pubmed publisher
    Acupuncture has a definite therapeutic effect on chronic obstructive pulmonary disease (COPD), and the cholinergic anti-inflammatory pathway (CAP) has been shown to be involved in regulation of inflammation...
  2. Dong Y, Li Y, Sun Y, Mao J, Yao F, Tian Y, et al. Bufei Jianpi granules improve skeletal muscle and mitochondrial dysfunction in rats with chronic obstructive pulmonary disease. BMC Complement Altern Med. 2015;15:51 pubmed publisher
    ..walk distance and quality of life, and benefited in 12-month follow-up in chronic obstructive pulmonary disease (COPD) patients with syndrome of lung-spleen qi deficiency...
  3. Suzuki Y, Sato T, Sugimoto M, Baskoro H, Karasutani K, Mitsui A, et al. Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. Biochem Biophys Res Commun. 2017;492:74-81 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is predominantly a cigarette smoke (CS)-triggered disease with features of chronic systemic inflammation...
  4. Pascual C, Galán E, Guerrero J, Colino R, Soler P, Calvo M, et al. Rationale and methods of the multicenter randomised trial of a heart failure management programme among geriatric patients (HF-Geriatrics). BMC Public Health. 2011;11:627 pubmed publisher
    ..hearing loss, cognitive impairment, Parkinson's disease, diabetes mellitus, chronic obstructive pulmonary disease (COPD), anaemia, or constitutional syndrome...
  5. Dunham Snary K, Wu D, Sykes E, Thakrar A, Parlow L, Mewburn J, et al. Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine. Chest. 2017;151:181-192 pubmed publisher
    ..Conversely, impaired HPV, whether due to disease (eg, COPD, sepsis) or vasodilator drugs, promotes systemic hypoxemia...
  6. Goto T, Hirayama A, Faridi M, Camargo C, Hasegawa K. Obesity and Severity of Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2018;15:184-191 pubmed publisher
    Obesity is relatively common among individuals with chronic obstructive pulmonary disease (COPD). However, little is known about the association of obesity with severity of acute exacerbation of COPD and in-hospital mortality...
  7. Guedán A, Swieboda D, Charles M, Toussaint M, Johnston S, Asfor A, et al. Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication. J Virol. 2017;91: pubmed publisher
    ..which in itself is a relatively trivial infection; however, in asthma and chronic obstructive pulmonary disease (COPD) patients, this virus is a major cause of exacerbations resulting in an increased use of medication, worsening ..
  8. Liu Z, Geng W, Jiang C, Zhao S, Liu Y, Zhang Y, et al. Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats. Exp Biol Med (Maywood). 2017;242:1534-1541 pubmed publisher
    ..of hydrogen-rich saline, a novel antioxidant, on tobacco smoke (TS)-induced chronic obstructive pulmonary disease (COPD) in rats and explore the underlying mechanism...
  9. Zhang M, Tang J, Li Y, Xie Y, Shan H, Chen M, et al. Curcumin attenuates skeletal muscle mitochondrial impairment in COPD rats: PGC-1?/SIRT3 pathway involved. Chem Biol Interact. 2017;277:168-175 pubmed publisher
    ..is to investigate the effect of curcumin on skeletal muscle mitochondria in chronic obstructive pulmonary disease (COPD) and its underlying mechanism...
  10. Clapp P, Jaspers I. Electronic Cigarettes: Their Constituents and Potential Links to Asthma. Curr Allergy Asthma Rep. 2017;17:79 pubmed publisher
    ..as smoking-associated clinical endpoints, such as cancer, bronchitis, and chronic obstructive pulmonary disease (COPD)...
  11. Hirano T, Yamada M, Sato K, Murakami K, Tamai T, Mitsuhashi Y, et al. Invasive pulmonary mucormycosis: rare presentation with pulmonary eosinophilia. BMC Pulm Med. 2017;17:76 pubmed publisher
    ..A 74-year-old Japanese man with asthma-COPD overlap underwent emergency surgery for a ruptured abdominal aortic aneurysm...
  12. MareÈ™ M, Moroti Constantinescu V, Denning D. The Burden of Fungal Diseases in Romania. J Fungi (Basel). 2018;4: pubmed publisher
    ..98/100,000 (1768 cases). The prevalence of chronic obstructive pulmonary disease (COPD) and asthma in adults is 6% and 6.5%, respectively...
  13. Li Y, Tian Y, Li J, Dong Y, Wang M, Feng S, et al. Bufei Yishen granules combined with acupoint sticking therapy suppress oxidative stress in chronic obstructive pulmonary disease rats: Via regulating peroxisome proliferator-activated receptor-gamma signaling. J Ethnopharmacol. 2016;193:354-361 pubmed publisher
    ..effective for treating the syndrome of lung-kidney qi deficiency in chronic obstructive pulmonary disease (COPD) patients...
  14. Shergis J, Di Y, Zhang A, Vlahos R, Helliwell R, Ye J, et al. Therapeutic potential of Panax ginseng and ginsenosides in the treatment of chronic obstructive pulmonary disease. Complement Ther Med. 2014;22:944-53 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is a major global health burden and will become the third largest cause of death in the world by 2030...
  15. Gan L, Li C, Wang J, Guo X. Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model. Int J Chron Obstruct Pulmon Dis. 2016;11:2765-2773 pubmed
    ..suggested that histone modification has a positive impact on various aspects associated with the progression of COPD. Histone deacetylase 2 (HDAC2) suppresses proinflammatory gene expression through deacetylation of core histones...
  16. Milger K, Holdt L, Teupser D, Huber R, Behr J, Kneidinger N. Identification of a novel SERPINA-1 mutation causing alpha-1 antitrypsin deficiency in a patient with severe bronchiectasis and pulmonary embolism. Int J Chron Obstruct Pulmon Dis. 2015;10:891-7 pubmed publisher
    ..She had never smoked, and had been diagnosed with COPD 9 years earlier. Three months previously, she had suffered a pulmonary embolism...
  17. Crotty Alexander L, Shin S, Hwang J. Inflammatory Diseases of the Lung Induced by Conventional Cigarette Smoke: A Review. Chest. 2015;148:1307-1322 pubmed publisher
    ..We review here the known cellular and molecular mechanisms of CS-induced diseases, including COPD, respiratory bronchiolitis-interstitial lung disease, desquamative interstitial pneumonia, acute eosinophilic ..
  18. Pal S, Khan K, China S, Mittal M, Porwal K, Shrivastava R, et al. Theophylline, a methylxanthine drug induces osteopenia and alters calciotropic hormones, and prophylactic vitamin D treatment protects against these changes in rats. Toxicol Appl Pharmacol. 2016;295:12-25 pubmed publisher
    ..is frequently used as an additive to medications for people suffering from chronic obstructive pulmonary diseases (COPD)...
  19. Magitta N, Walker R, Apte K, Shimwela M, Mwaiselage J, Sanga A, et al. Prevalence, risk factors and clinical correlates of COPD in a rural setting in Tanzania. Eur Respir J. 2018;51: pubmed publisher
    Chronic obstructive pulmonary disease (COPD) causes substantial burden of disease in developed countries, but there are limited data from Africa...
  20. Baba S, Takashima T, Hirota M, Kawashima M, Horikawa E. Relationship between pulmonary function and elevated glycated hemoglobin levels in health checkups: A cross-sectional observational study in Japanese participants. J Epidemiol. 2017;27:511-515 pubmed publisher
    ..tumor necrosis factor alpha soluble receptor, both of which are elevated in chronic obstructive pulmonary disease (COPD)...
  21. Kemeny A, Csekő K, Szitter I, Varga Z, Bencsik P, Kiss K, et al. Integrative characterization of chronic cigarette smoke-induced cardiopulmonary comorbidities in a mouse model. Environ Pollut. 2017;229:746-759 pubmed publisher
    ..inflammatory cascades and consequent tissue damage are the main causes of chronic obstructive pulmonary disease (COPD)...
  22. Şanel S, Sezgin G, Sarıman N, Ugutmen E, Solakoglu C. Bilateral non-traumatic hip fractures in a heavy smoker COPD patient on inhaled steroids. Arch Osteoporos. 2016;11:8 pubmed publisher
    ..He had a background of chronic obstructive pulmonary disease (COPD) and had been taking inhaled steroids (budesonide) 800 µg per day for 10 years...
  23. Liu C, Lee T, Chen Y, Liang C, Wang S, Lue J, et al. PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-κB-dependent pathway. Part Fibre Toxicol. 2018;15:4 pubmed publisher
    ..Furthermore, patients with chronic obstructive pulmonary disease (COPD) had higher plasma levels of ICAM-1 and IL-6 compared to healthy subjects...
  24. Nicolini A, Barbagelata E, Tagliabue E, Colombo D, Monacelli F, Braido F. Gender differences in chronic obstructive pulmonary diseases: a narrative review. Panminerva Med. 2018;60:192-199 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is generally considered to be prevalent in males...
  25. Anello P, Cestari L, Canova C, Vianello L, Pistollato S, Lorenzet K, et al. [Investigation on the health effects of traffic-related air pollution from Mestre motorway (Veneto Region, Northern Italy)]. Epidemiol Prev. 2015;39:251-60 pubmed
    ..12; 95%CI 1.01-1.26) in both genders. Results were borderline for COPD in males (OR: 1.17; 95%CI 0.97-1.41)...
  26. Dodd A, Bulka C, Jahangir A, Mir H, Obremskey W, Sethi M. Predictors of 30-day mortality following hip/pelvis fractures. Orthop Traumatol Surg Res. 2016;102:707-10 pubmed publisher
    ..functional status, history of congestive heart failure (CHF), history of chronic obstructive pulmonary disease (COPD), a recent blood transfusion, and the postoperative complications: pneumonia, myocardial infarction, stroke, and ..
  27. Koulenti D, Tsigou E, Rello J. Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study. Eur J Clin Microbiol Infect Dis. 2017;36:1999-2006 pubmed publisher
    ..NP resulted in 6 % higher mortality, longer ICU stay and duration of mechanical ventilation (12 and 10 days). COPD and age ?45 years were not associated with higher VAP incidence but did correlate with increased mortality...
  28. Barnes P. Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2016;138:16-27 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation affecting predominantly the lung parenchyma and peripheral airways that results in largely irreversible and progressive airflow limitation...
  29. Tang Y, Cai Q, Wang Y, Fan S, Zhang Z, Xiao M, et al. Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD. Biosci Rep. 2017;37: pubmed publisher
    ..apoptosis belonging to alveolar epithelial cells (AECs) in rat models with chronic obstructive pulmonary disease (COPD)...
  30. Williams M, Cafarella P, Paquet C, Frith P. Cognitive Behavioral Therapy for Management of Dyspnea: A Pilot Study. Respir Care. 2015;60:1303-13 pubmed publisher
    In patients with COPD, psychological interventions usually target generalized anxiety and depression rather than the sensation of breathlessness...
  31. Jácome C, Marques A. Computerized Respiratory Sounds Are a Reliable Marker in Subjects With COPD. Respir Care. 2015;60:1264-75 pubmed publisher
    Computerized respiratory sounds have shown potential in monitoring respiratory status in patients with COPD. However, the variability and reliability of this promising marker in COPD are unknown...
  32. Ranjita R, Hankey A, Nagendra H, Mohanty S. Yoga-based pulmonary rehabilitation for the management of dyspnea in coal miners with chronic obstructive pulmonary disease: A randomized controlled trial. J Ayurveda Integr Med. 2016;7:158-166 pubmed publisher
    ..limitation in coal miners resulting in dyspnea, fatigue, and eventually chronic obstructive pulmonary disease (COPD)...
  33. Zhou Z, Zhou A, Zhao Y, Chen P. Evaluating the Clinical COPD Questionnaire: A systematic review. Respirology. 2017;22:251-262 pubmed publisher
    The Clinical COPD Questionnaire (CCQ) is recommended by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) to evaluate health status in patients with COPD...
  34. Qiu H, Tian L, Ho K, Yu I, Thach T, Wong C. Who is more vulnerable to death from extremely cold temperatures? A case-only approach in Hong Kong with a temperate climate. Int J Biometeorol. 2016;60:711-7 pubmed publisher
    ..causes including hypertensive diseases, stroke, congestive heart failure, chronic obstructive pulmonary disease (COPD), and pneumonia...
  35. Wu Q, Jiang D, Matsuda J, Ternyak K, Zhang B, Chu H. Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production. Am J Respir Cell Mol Biol. 2016;55:429-38 pubmed publisher
    ..airway epithelial senescence has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD), although the underlying mechanisms remain largely unknown...
  36. El Mallakh P, McPeak D, Khara M, Okoli C. Smoking Behaviors and Medical Co-Morbidities in Patients With Mental Illnesses. Arch Psychiatr Nurs. 2016;30:740-746 pubmed publisher
    ..with psychotic disorders included associations between a history of emphysema/chronic obstructive pulmonary (COPD) disease and cigarettes smoked per day (r's=.35, p≤.01), Confidence in quitting (r's=-.33, p≤...
  37. Simon C, Allou N, Schlossmacher P, Gendry T, Delay L, Gazaille V. [Lung transplantation in Reunion Island, current situation from January 2005 till May 2015]. Rev Pneumol Clin. 2017;73:75-80 pubmed publisher
    ..with pulmonary fibrosis, 1 patients with bronchiectasis, 1 patient with chronic obstructive pulmonary disease (COPD) and 1 patient with pulmonary arterial hypertension...
  38. Begic A, Opanković E, Cukić V, Lindqvist A, Miniati M, Bajc M. Ancillary findings assessed by ventilation/perfusion tomography. Impact and clinical outcome in patients with suspected pulmonary embolism. Nuklearmedizin. 2015;54:223-30 pubmed publisher
    ..Moreover, it is possible to recognize other pathologies in addition to PE, such as pneumonia, COPD and left heart failure (LHF)...
  39. Babaoglu E, Kilic H, Hezer H, Dag O, Parlak E, Sentürk A, et al. Comparison of thiol/disulphide homeostasis parameters in patients with COPD, asthma and ACOS. Eur Rev Med Pharmacol Sci. 2016;20:1537-43 pubmed
    Chronic obstructive pulmonary disease (COPD), asthma and asthma-COPD overlap syndrome (ACOS) are obstructive pulmonary disorders with different manifestations. Status of oxidation in tissues is important in obstructive pulmonary disorders...
  40. Burney P. Chronic respiratory disease - the acceptable epidemic?. Clin Med (Lond). 2017;17:29-32 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is a major cause of disability and death in the UK but is an even greater problem in low income countries. It is assumed by many to be almost entirely attributed to smoking...
  41. Holas P, MichaÅ‚owski J, GawÄ™da Å, DomagaÅ‚a Kulawik J. Agoraphobic avoidance predicts emotional distress and increased physical concerns in chronic obstructive pulmonary disease. Respir Med. 2017;128:7-12 pubmed publisher
    Anxiety and panic attacks are more common in chronic obstructive pulmonary disease (COPD) than in the overall population...
  42. Lai K, Chen R, Peng W, Zhan W. Non-asthmatic eosinophilic bronchitis and its relationship with asthma. Pulm Pharmacol Ther. 2017;47:66-71 pubmed publisher
    ..long term follow-up study suggested that NAEB should be a distinct entity rather than an early stage of asthma or COPD. The relapse rate is high after treatment...
  43. Bruguera Avila N, MarIn A, Garcia Olivé I, Radua J, Prat C, Gil M, et al. Effectiveness of treatment with nebulized colistin in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2017;12:2909-2915 pubmed publisher
    To analyze whether the introduction of nebulized colistin in patients with chronic obstructive pulmonary disease (COPD) and infection with Pseudomonas aeruginosa (PA) is associated with a decrease of the number and duration of ..
  44. Siouta N, Van Beek K, Payne S, Radbruch L, Preston N, Hasselaar J, et al. Is the content of guidelines/pathways a barrier for the integration of palliative Care in Chronic Heart Failure (CHF) and chronic pulmonary obstructive disease (COPD)? A comparison with the case of cancer in Europe. BMC Palliat Care. 2017;16:62 pubmed publisher
    ..palliative care (PC) services between cancer and Chronic Heart Failure (CHF)/Chronic Obstructive Pulmonary Disease (COPD) patients which also translates into discrepancies in the level of integration of PC...
  45. Toczyska I, Zwolińska E, Chcialowski A. Influence of Inhaled Corticosteroids on Bronchial Inflammation and Pulmonary Function in Chronic Obstructive Pulmonary Disease with Moderate Obstruction. Adv Exp Med Biol. 2018;1047:41-52 pubmed publisher
    ..respiratory tract and lung parenchyma underlies the pathogenesis of chronic obstructive pulmonary disease (COPD)...
  46. Oh J, Lee Y, Min K, Lee S, Shim J, Kang K, et al. Osteoporosis in Patients with Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome. Tuberc Respir Dis (Seoul). 2018;81:73-79 pubmed publisher
    ..in patients with chronic inflammatory airway diseases, including asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap syndrome (ACOS)...
  47. Guiedem E, Ikomey G, Nkenfou C, Walter P, Mesembe M, Chegou N, et al. Chronic obstructive pulmonary disease (COPD): neutrophils, macrophages and lymphocytes in patients with anterior tuberculosis compared to tobacco related COPD. BMC Res Notes. 2018;11:192 pubmed publisher
    The inflammatory profile of chronic obstructive pulmonary disease (COPD) related to tobacco is known in certain studies while that of the post tuberculosis form is not yet known...
  48. Sharma G, Hanania N, Shim Y. The aging immune system and its relationship to the development of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2009;6:573-80 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the lungs that usually manifests late in life. Physiologic and immunologic changes that occur in COPD often mimic changes seen in the aging lung...
  49. Siederer S, Allen A, Yang S. Population Pharmacokinetics of Inhaled Fluticasone Furoate and Vilanterol in Subjects with Chronic Obstructive Pulmonary Disease. Eur J Drug Metab Pharmacokinet. 2016;41:743-758 pubmed
    ..clinical studies in healthy subjects and from global trials in patients with chronic obstructive pulmonary disease (COPD)...
  50. Ferrari A, Compagnoni A, Nandeuil A, Maison Blanche P. Evaluation of the Effects of CHF6001, an Inhaled PDE4 Inhibitor, on Cardiac Repolarization and Cardiac Arrhythmias in Healthy Volunteers. J Cardiovasc Pharmacol. 2016;68:41-8 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is a multicomponent condition characterized by airway inflammation and associated to comorbidities, including cardiovascular diseases...
  51. Fabbri L, Kerwin E, Spangenthal S, Ferguson G, Rodriguez Roisin R, Pearle J, et al. Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension™ Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD. Respir Res. 2016;17:109 pubmed publisher
    ..dose range to determine an optimal dose for patients with moderate-to-severe chronic obstructive pulmonary disease (COPD)...
  52. Schumacher F, Schubert S, Hannus M, Sönnichsen B, Ittrich C, Kreideweiss S, et al. RNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical Stress. PLoS ONE. 2016;11:e0166352 pubmed publisher
    Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent condition characterized by inflammation and progressive obstruction of the airways...
  53. Reilev M, Lykkegaard J, Halling A, Vestbo J, Søndergaard J, Pottegård A. Stability of the frequent COPD exacerbator in the general population: A Danish nationwide register-based study. NPJ Prim Care Respir Med. 2017;27:25 pubmed publisher
    ..VARIATIONS IN DISEASE PROGRESSION: Patients with chronic obstructive pulmonary disease (COPD) who suffer from frequent exacerbations do not necessarily persist with such severity over time...
  54. Seys L, Widagdo W, Verhamme F, Kleinjan A, Janssens W, Joos G, et al. DPP4, the MERS coronavirus receptor, is upregulated in lungs of smokers and COPD patients. Clin Infect Dis. 2017;: pubmed publisher
    ..Smokers and chronic obstructive pulmonary disease (COPD) patients have been reported to be more susceptible to MERS-CoV infection...
  55. Benam K, Konigshoff M, Eickelberg O. Breaking the In Vitro Barrier in Respiratory Medicine: Engineered Microphysiological Systems for COPD and Beyond. Am J Respir Crit Care Med. 2017;: pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is a leading global health problem; however, our ability to understand the disease pathogenic processes and discover new pharmacotherapies have been significantly hindered due to lack of ..
  56. Johnstone T, Smith K, Koziol White C, Li F, Kazarian A, Corpuz M, et al. PDE8 is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2AR-AC6. Am J Respir Cell Mol Biol. 2017;: pubmed publisher
    ..In airway diseases such as asthma and COPD, PDE8 may represent a novel therapeutic target to modulate HASM responsiveness and airway remodeling.
  57. Barken T, Thygesen E, Söderhamn U. Advancing beyond the system: telemedicine nurses' clinical reasoning using a computerised decision support system for patients with COPD - an ethnographic study. BMC Med Inform Decis Mak. 2017;17:181 pubmed publisher
    ..Future studies are warranted to develop more accurate algorithms, increase system maturity, and improve the integration of the digital clinical information with clinical experiences, to support telemedicine nurses' reasoning process. ..
  58. Seys L, Verhamme F, Schinwald A, Hammad H, Cunoosamy D, Bantsimba Malanda C, et al. Role of B Cell-Activating Factor in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2015;192:706-18 pubmed publisher
    ..In chronic obstructive pulmonary disease (COPD), lymphoid follicles have been associated with disease severity, and overexpression of BAFF has been demonstrated ..
  59. Smith M, Chang A, Hodges P. Balance recovery is compromised and trunk muscle activity is increased in chronic obstructive pulmonary disease. Gait Posture. 2016;43:101-7 pubmed publisher
    Increased respiration in chronic obstructive pulmonary disease (COPD) requires greater abdominal muscle activation, which may impact on contribution of the trunk to postural control...
  60. Haraguchi M, Nakamura H, Sasaki M, Miyazaki M, Chubachi S, Takahashi S, et al. Determinants of chronic obstructive pulmonary disease severity in the late-elderly differ from those in younger patients. BMC Res Notes. 2016;9:7 pubmed publisher
    Although the age range of chronic obstructive pulmonary disease (COPD) patients is broad, few studies have focused on the effects of age on disease characteristics...
  61. Liu Y, Kheradmand F, Davis C, Scheurer M, Wheeler D, Tsavachidis S, et al. Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. J Thorac Oncol. 2016;11:52-61 pubmed publisher
    The association between smoking-induced chronic obstructive pulmonary disease (COPD) and lung cancer (LC) is well documented...
  62. Rodrigues F, Papoila A, Ligeiro D, Gomes M, Trindade H. Acute exercise amplifies inflammation in obese patients with COPD. Rev Port Pneumol (2006). 2016;22:315-322 pubmed publisher
    Systemic inflammation has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD) systemic effects...
  63. Jeppesen S, Hansen N, Schytte T, Nielsen M, Hansen O. Comparison of survival of chronic obstructive pulmonary disease patients with or without a localized non-small cell lung cancer. Lung Cancer. 2016;100:90-95 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) and non-small cell lung cancer (NSCLC) are often co-existing diseases with poor prognosis...
  64. García García S, Carazo Fernández L, Juan García J, Naveiro Rilo J. [Chronic obstructive pulmonary disease in real life. LEONPOC study]. Aten Primaria. 2017;49:603-610 pubmed publisher
    The purpose of this study was to evaluate different characteristics of COPD patients according to phenotypes and GOLD guidelines.according to GesEPOC phenotypes and GOLD 2011 ABCD guidelines and pharmacological treatment agreement...
  65. Bodas M, Vij N. Augmenting autophagy for prognosis based intervention of COPD-pathophysiology. Respir Res. 2017;18:83 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is foremost among the non-reversible fatal ailments where exposure to tobacco/biomass-smoke and aging are the major risk factors for the initiation and progression of the obstructive lung ..
  66. Zhang Y, Ni H, Zhou H. Study on the expression of Toll-like receptor 4 and matrix metalloproteinase-9 in patients with chronic obstructive pulmonary disease and their clinical significance. Eur Rev Med Pharmacol Sci. 2017;21:2185-2191 pubmed
    ..receptor 4 (TLR4) and matrix metalloproteinase-9 (MMP-9) in patients with chronic obstructive pulmonary disease (COPD) and their clinical significance...
  67. Montes de Oca M, Menezes A, Wehrmeister F, López Varela M, Casas A, Ugalde L, et al. Adherence to inhaled therapies of COPD patients from seven Latin American countries: The LASSYC study. PLoS ONE. 2017;12:e0186777 pubmed publisher
    This study assessed the adherence profiles to inhaled therapies and the agreement between two patient self-report adherence methods in stable COPD lpatients from seven Latin American countries.
  68. Shivappa N, Blair C, Prizment A, Jacobs D, Steck S, Hebert J. Association between inflammatory potential of diet and mortality in the Iowa Women's Health study. Eur J Nutr. 2016;55:1491-502 pubmed publisher
    ..17; 95 % CI 1.05-1.30; p-trend = 0.001) and chronic obstructive pulmonary disease (COPD) mortality (HRQ4vsQ1 1.43; 95 % CI 1.18-1.75; p-trend = 0.0006)...
  69. Marcos P, Nieto Codesido I, de Jorge Dominguez Pazos S, Huerta A, Marquez E, Maiso A, et al. Treatment With Systemic Steroids in Severe Chronic Obstructive Pulmonary Disease Exacerbations: Use of Short Regimens in Routine Clinical Practice and Their Impact on Hospital Stay. Arch Bronconeumol. 2017;53:611-615 pubmed publisher
    It is not known whether clinical practice guidelines for the treatment of COPD exacerbations with short coursesofsystemic corticosteroids(SC-SCS) are followed in clinical practice...
  70. Lai T, Tian B, Cao C, Hu Y, Zhou J, Wang Y, et al. HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD. Chest. 2018;153:863-875 pubmed publisher
    Although airway remodeling is a central feature of COPD, the mechanisms underlying its development have not been fully elucidated...
  71. Bournival R, Coutu R, Goettel N, Yang C, Cantin Lafleur A, Lemieux C, et al. Preferences and Inhalation Techniques for Inhaler Devices Used by Patients with Chronic Obstructive Pulmonary Disease. J Aerosol Med Pulm Drug Deliv. 2017;: pubmed publisher
    ..are often overlooked when selecting maintenance treatments for patients with chronic obstructive pulmonary disease (COPD), but are important issues in ensuring drug efficacy and patient adherence...
  72. North C, Allen J, Okello S, Sentongo R, Kakuhikire B, Ryan E, et al. HIV Infection, Pulmonary Tuberculosis, and COPD in Rural Uganda: A Cross-Sectional Study. Lung. 2018;196:49-57 pubmed publisher
    HIV is associated with chronic obstructive pulmonary disease (COPD) in high resource settings. Similar relationships are less understood in low resource settings...
  73. Carder M, Darnton A, Gittins M, Stocks S, Ross D, Barber C, et al. Chest physician-reported, work-related, long-latency respiratory disease in Great Britain. Eur Respir J. 2017;50: pubmed publisher
    ..4 (4.8-6.0); pneumoconiosis, 1.9 (1.7-2.2); lung cancer, 0.8 (0.6-1.0); chronic obstructive pulmonary disease (COPD), 0.3 (0.2-0.4)...
  74. Liang G, Bowen J. Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based Rationales. Curr Top Med Chem. 2016;16:1506-29 pubmed
    ..with indications ranging from thrombosis and inflammation to asthma and chronic obstructive pulmonary disease (COPD)...
  75. Werlé C, Anstine D, Karmazin L, Bailly C, Ricard L, Djukic J. New Pd(II) hemichelates devoid of incipient bridging COPd interactions. Dalton Trans. 2016;45:607-17 pubmed publisher
    ..moiety and the Pd(ii) centers, which according to X-ray diffraction analyses lack significant incipient bridging COPd character...
  76. Kim H, Lee J, Park Y, Lee C, Lee S, Yim J, et al. Impact of GOLD groups of chronic pulmonary obstructive disease on surgical complications. Int J Chron Obstruct Pulmon Dis. 2016;11:281-7 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is associated with increased postoperative complications...
  77. Li H, Liu Y, Wang L, Shen T, DU W, Liu Z, et al. High apolipoprotein M serum levels correlate with chronic obstructive pulmonary disease. Lipids Health Dis. 2016;15:59 pubmed publisher
    ..HDL), namely apolipoprotein M (apoM), were found to be associated with chronic obstructive pulmonary disease (COPD). The aim of this study was to evaluate the association between apoM and COPD severity...
  78. Klotz R, Hofer S, Schellhaaß A, Dörr Harim C, Tenckhoff S, Bruckner T, et al. Intravenous versus epidural analgesia to reduce the incidence of gastrointestinal complications after elective pancreatoduodenectomy (the PAKMAN trial, DRKS 00007784): study protocol for a randomized controlled trial. Trials. 2016;17:194 pubmed publisher
    ..Patients with chronic pancreatitis, severe chronic obstructive pulmonary disease (COPD), American Society of Anesthesiologists (ASA) physical status classification???IV, or chronic pain syndrome will be ..
  79. Jiang T, Shi L, Wei L, Li X, Yang S, Wang C, et al. Serum amyloid A, protein Z, and C4b-binding protein ? chain as new potential biomarkers for pulmonary tuberculosis. PLoS ONE. 2017;12:e0173304 pubmed publisher
    ..47 abnormally expressed proteins between patients with TB or pneumonia and chronic obstructive pulmonary disease (COPD)...
  80. Murray L, Dunmore R, Camelo A, Da Silva C, Gustavsson M, Habiel D, et al. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium. Respir Res. 2017;18:82 pubmed publisher
    ..Apoptosis was significantly greater in unstimulated cells from COPD patients compared to control, but proliferation and CXCL8 release were not different...
  81. Abdulai R, Jellesmark Jensen T, Patel N, Polkey M, Jansson P, Celli B, et al. Deterioration of Limb Muscle Function During Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017;: pubmed publisher
    Important features of both stable and acute exacerbation of COPD are skeletal muscle weakness and wasting...
  82. Alzoubi A, Ghazwi R, Alzoubi K, Alqudah M, Kheirallah K, Khabour O, et al. Vascular endothelial growth factor receptor inhibition enhances chronic obstructive pulmonary disease picture in mice exposed to waterpipe smoke. Folia Morphol (Warsz). 2018;77:447-455 pubmed publisher
    Chronic obstructive pulmonary disease (COPD) is marked by destruction of alveolar architecture. Preclinical modelling for COPD is challenging...
  83. Margolick J, Chen W, Wiseman S. Systematic Review and Meta-analysis of Unplanned Reoperations, Emergency Department Visits, and Hospital Readmission After Thyroidectomy. Thyroid. 2018;: pubmed publisher
    ..Older age, thyroid cancer, dependent functional status, higher ASA score, diabetes, COPD, steroid use, hemodialysis and recent weight loss increase the risk of hospital readmission after thyroid surgery...
  84. van Boven J, Ryan D, Eakin M, Canonica G, Barot A, Foster J. Enhancing Respiratory Medication Adherence: The Role of Health Care Professionals and Cost-Effectiveness Considerations. J Allergy Clin Immunol Pract. 2016;4:835-46 pubmed publisher
    ..in most patients with long-term respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD)...
  85. Lawrence P, Kolsum U, Gupta V, Donaldson G, Singh R, Barker B, et al. Characteristics and longitudinal progression of chronic obstructive pulmonary disease in GOLD B patients. BMC Pulm Med. 2017;17:42 pubmed publisher
    The characteristics and natural history of GOLD B COPD patients are not well described...
  86. Enemark M, Midttun M, Winge K. Evaluating Outcomes for Older Patients with Parkinson's Disease or Dementia with Lewy Bodies who have been Hospitalised for Hip Fracture Surgery: Potential Impact of Drug Administration. Drugs Aging. 2017;34:387-392 pubmed publisher
    ..a comparable group of patients who were admitted with a hip fracture and chronic obstructive pulmonary disease (COPD)...
  87. Milanowska J, Mackiewicz B, Węgorowski P, Milanowski J, Milanowski P, Makara Studzinska M. The quality of life of farmers with chronic obstructive pulmonary disease (COPD). Ann Agric Environ Med. 2017;24:283-287 pubmed publisher
    lt;b>Introduction and objective.</b> COPD is a medical state characterized by chronically poor airflow, and typically worsens over time...
  88. Walker S, Andrew S, Hodson M, Roberts C. Stage 1 development of a patient-reported experience measure (PREM) for chronic obstructive pulmonary disease (COPD). NPJ Prim Care Respir Med. 2017;27:47 pubmed publisher
    ..are aiming to provide effective patient-centered care for those with chronic obstructive pulmonary disease (COPD)...
  89. Ceriana P, Vitacca M, Carlucci A, Paneroni M, Pisani L, Nava S. Changes of Respiratory Mechanics in COPD Patients from Stable State to Acute Exacerbations with Respiratory Failure. COPD. 2017;14:150-155 pubmed publisher
    ..The aim of this study was to evaluate changes of respiratory mechanics in COPD patients comparing data observed during EXCOPD with those observed during stable state in the recovery phase...
  90. Lipson D, Barnacle H, Birk R, Brealey N, Locantore N, Lomas D, et al. FULFIL Trial: Once-Daily Triple Therapy for Patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017;196:438-446 pubmed publisher
    ..ICS)/long-acting ?2-agonist (LABA) therapy in patients with chronic obstructive pulmonary disease (COPD) are limited...
  91. Nakken N, Janssen D, van den Bogaart E, Muris J, Vercoulen J, Custers F, et al. Knowledge gaps in patients with COPD and their proxies. BMC Pulm Med. 2017;17:136 pubmed publisher
    Although proxies of patients with chronic obstructive pulmonary disease (COPD) need health-related knowledge to support patients in managing their disease, their current level of knowledge remains unknown...
  92. Castanhel F, Grosseman S. Quality of Communication Questionnaire for COPD patients receiving palliative care: translation and cross-cultural adaptation for use in Brazil. J Bras Pneumol. 2017;43:357-362 pubmed publisher
    To translate the Quality of Communication Questionnaire (QOC) to Portuguese and adapt it for use in Brazil in COPD patients receiving palliative care.