APOBEC3C

Summary

Gene Symbol: APOBEC3C
Description: apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Alias: A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3, DNA dC->dU-editing enzyme APOBEC-3C, apolipoprotein B editing enzyme catalytic polypeptide-like 3C, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C, phorbolin I
Species: human
Products:     APOBEC3C

Top Publications

  1. Albin J, Harris R. Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics. Expert Rev Mol Med. 2010;12:e4 pubmed publisher
    ..We also summarise, for the first time, current clinical data on the in vivo effects of APOBEC3 proteins, and survey strategies and progress towards developing therapeutics aimed at the APOBEC3-Vif axis. ..
  2. Doehle B, Schäfer A, Wiegand H, Bogerd H, Cullen B. Differential sensitivity of murine leukemia virus to APOBEC3-mediated inhibition is governed by virion exclusion. J Virol. 2005;79:8201-7 pubmed
    ..Moreover, these results suggest that APOBEC3 proteins may help prevent the zoonotic infection of humans by simple retroviruses and provide a mechanism for how simple retroviruses can avoid inhibition by APOBEC3 family members...
  3. Muckenfuss H, Hamdorf M, Held U, Perkovic M, Lower J, Cichutek K, et al. APOBEC3 proteins inhibit human LINE-1 retrotransposition. J Biol Chem. 2006;281:22161-72 pubmed
    ..We demonstrate that APOBEC3C and APOBEC3B were endogenously expressed in HeLa cells...
  4. Rose K, Marin M, Kozak S, Kabat D. Regulated production and anti-HIV type 1 activities of cytidine deaminases APOBEC3B, 3F, and 3G. AIDS Res Hum Retroviruses. 2005;21:611-9 pubmed
    ..Thus, A3A, A3B, and A3C had weak but significant anti-HIV-1 activities and did not dominantly interfere with A3G or A3F antiviral functions...
  5. Niewiadomska A, Tian C, Tan L, Wang T, Sarkis P, Yu X. Differential inhibition of long interspersed element 1 by APOBEC3 does not correlate with high-molecular-mass-complex formation or P-body association. J Virol. 2007;81:9577-83 pubmed
    ..The catalytic domain of APOBEC3 proteins may be important for proper folding and target factors such as RNA or protein interaction in addition to cytidine deamination. ..
  6. Zhang W, Zhang X, Tian C, Wang T, Sarkis P, Fang Y, et al. Cytidine deaminase APOBEC3B interacts with heterogeneous nuclear ribonucleoprotein K and suppresses hepatitis B virus expression. Cell Microbiol. 2008;10:112-21 pubmed
    ..In addition, A3B protein may be a broad antiviral host factor. Thus, regulated A3B expression may contribute to non-cytolytic HBV clearance in vivo. ..
  7. Kock J, Blum H. Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H. J Gen Virol. 2008;89:1184-91 pubmed publisher
    ..This study assessed APOBEC3G, APOBEC3C and APOBEC3H, three members of this protein family present in human liver, for their ability to edit HBV genomes...
  8. Dang Y, Abudu A, Son S, Harjes E, Spearman P, Matsuo H, et al. Identification of a single amino acid required for APOBEC3 antiretroviral cytidine deaminase activity. J Virol. 2011;85:5691-5 pubmed publisher
    ..Conversely, replacing A3F Y307 with a cysteine or inserting a similar cysteine into A3B or A3G disrupted the anti-HIV activity of A3. Further investigation uncovered that C320 significantly reduces A3DE catalytic activity. ..
  9. Langlois M, Beale R, Conticello S, Neuberger M. Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities. Nucleic Acids Res. 2005;33:1913-23 pubmed
    ..Here, we compare APOBEC3F and APOBEC3G to APOBEC3C, a single-domained deaminase that can also act on both HIV-1 and MLV...

More Information

Publications99

  1. Chiu Y, Greene W. The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Annu Rev Immunol. 2008;26:317-53 pubmed publisher
  2. Esnault C, Priet S, Ribet D, Heidmann O, Heidmann T. Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements. Retrovirology. 2008;5:75 pubmed publisher
  3. Browne E, Littman D. Species-specific restriction of apobec3-mediated hypermutation. J Virol. 2008;82:1305-13 pubmed
    ..These results suggest that MLV has evolved specific mechanisms to block the ability of Apobec proteins to mediate deaminase-dependent hypermutation...
  4. Yu Q, Chen D, König R, Mariani R, Unutmaz D, Landau N. APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. J Biol Chem. 2004;279:53379-86 pubmed
    ..We report here that two additional APOBEC3 family members, APOBEC3B and APOBEC3C, have potent antiviral activity against simian immuno-deficiency virus (SIV), but not HIV-1...
  5. Cullen B. Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors. J Virol. 2006;80:1067-76 pubmed
  6. Zhang W, Huang M, Wang T, Tan L, Tian C, Yu X, et al. Conserved and non-conserved features of HIV-1 and SIVagm Vif mediated suppression of APOBEC3 cytidine deaminases. Cell Microbiol. 2008;10:1662-75 pubmed publisher
    Human cytidine deaminase APOBEC3C (A3C) acts as a potent inhibitor of SIVagm and can be regulated by both HIV-1 and SIVagm Vif. The mechanism by which Vif suppresses A3C is unknown...
  7. Hultquist J, Lengyel J, Refsland E, LaRue R, Lackey L, Brown W, et al. Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1. J Virol. 2011;85:11220-34 pubmed publisher
    ..On the other hand, neither human nor rhesus APOBEC3A, APOBEC3B, nor APOBEC3C had a significant impact on HIV-1 replication...
  8. Wang T, Zhang W, Tian C, Liu B, Yu Y, Ding L, et al. Distinct viral determinants for the packaging of human cytidine deaminases APOBEC3G and APOBEC3C. Virology. 2008;377:71-9 pubmed publisher
    ..We have now demonstrated that APOBEC3C (A3C) can be efficiently packaged into HIV-1 virions that are deficient for viral genomic RNA...
  9. Stenglein M, Burns M, Li M, Lengyel J, Harris R. APOBEC3 proteins mediate the clearance of foreign DNA from human cells. Nat Struct Mol Biol. 2010;17:222-9 pubmed publisher
    ..The efficiency and fidelity of genetic engineering, gene therapy, and DNA vaccination are likely to be influenced by this anti-DNA defense system. ..
  10. Suspène R, Aynaud M, Guetard D, Henry M, Eckhoff G, Marchio A, et al. Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism. Proc Natl Acad Sci U S A. 2011;108:4858-63 pubmed publisher
    ..Nonetheless, hyper- and lightly mutated sequences went hand in hand, raising the hypothesis that recurrent low-level mutation by APOBEC3A could catalyze the transition from a healthy to a cancer genome...
  11. Jarmuz A, Chester A, Bayliss J, Gisbourne J, Dunham I, Scott J, et al. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics. 2002;79:285-96 pubmed
    ..Tissue-specific expression of these genes in a variety of cell lines, along with other evidence, suggests a role for these enzymes in growth or cell cycle control. ..
  12. Mulder L, Harari A, Simon V. Cytidine deamination induced HIV-1 drug resistance. Proc Natl Acad Sci U S A. 2008;105:5501-6 pubmed publisher
  13. Chen H, Lilley C, Yu Q, Lee D, Chou J, Narvaiza I, et al. APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. Curr Biol. 2006;16:480-5 pubmed
    ..They also highlight the functional differences between APOBEC3 proteins. The APOBEC3 family members have distinct functions and may have evolved to resist various classes of genetic elements. ..
  14. Wedekind J, Dance G, Sowden M, Smith H. Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. Trends Genet. 2003;19:207-16 pubmed
    ..In light of the hypothesis that these proteins might represent novel mRNA editing systems that could affect proteome diversity, we consider their structure, expression and relevance to biomedically significant processes or pathologies. ..
  15. Bourara K, Liegler T, Grant R. Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1. PLoS Pathog. 2007;3:1477-85 pubmed
    ..Here we show that in APOBEC3C (A3C)-expressing cells infected with the patient-derived HIV-1 molecular clones 210WW, 210WM, 210MW, and 210MM, ..
  16. Baumert T, Rösler C, Malim M, Von Weizsacker F. Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C. Hepatology. 2007;46:682-9 pubmed
    APOBEC3G (A3G) and APOBEC3C (A3C), 2 members of the APOBEC family, are cellular cytidine deaminases displaying broad antiretroviral activity...
  17. Stauch B, Hofmann H, Perkovic M, Weisel M, Kopietz F, Cichutek K, et al. Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation. Proc Natl Acad Sci U S A. 2009;106:12079-84 pubmed publisher
    ..In this study we modeled and probed the structure of APOBEC3C (A3C), a single-domain A3 with strong antilentiviral activity...
  18. Peng G, Greenwell Wild T, Nares S, Jin W, Lei K, Rangel Z, et al. Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression. Blood. 2007;110:393-400 pubmed
    ..Differences in promiscuity of monocytes, macrophages, and DCs can be defined, at least partly, by disparities in APOBEC expression, with implications for enhancing cellular defenses against HIV-1. ..
  19. Guo J, Su Y, Zhong C, Ming G, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell. 2011;145:423-34 pubmed publisher
    ..Our study suggests a TET1-induced oxidation-deamination mechanism for active DNA demethylation in mammals. ..
  20. Suspène R, Aynaud M, Koch S, Pasdeloup D, Labetoulle M, Gaertner B, et al. Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo. J Virol. 2011;85:7594-602 pubmed publisher
    ..This is indeed the case for herpes simplex virus 1 (HSV-1) in tissue culture, where APOBEC3C (A3C) overexpression can reduce virus titers and the particle/PFU ratio ?10-fold...
  21. Garrett J, Sampson C, Plett P, Crisler R, Parker J, Venezia R, et al. Characterization and Etiology of Swollen Muzzles in Irradiated Mice. Radiat Res. 2019;191:31-42 pubmed publisher
    ..number of experiments in which mice that have received total-body irradiation (TBI) or partial-body irradiation (PBI) develop swollen muzzles, drastic thickening of the upper lip and redness, bruising and/or swelling around the nose ..
  22. Adolph M, Ara A, Feng Y, Wittkopp C, Emerman M, Fraser J, et al. Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization. Nucleic Acids Res. 2017;45:3378-3394 pubmed publisher
    ..A polymorphism in human APOBEC3C (A3C) that encodes an S188I mutation increases the enzymatic activity of the protein and its ability to restrict ..
  23. Ferrailo D, Veitz Keenan A. No clinical quantifiable benefits between non-surgical and surgical endodontic treatment. Evid Based Dent. 2017;18:75-76 pubmed publisher
    ..64; one RCT, 250 participants; low quality evidence).There was some evidence that using a papilla base incision (PBI) may be beneficial for preservation of the interdental papilla compared with complete papilla mobilisation (one RCT ..
  24. Yellowhair T, Noor S, Mares B, Jose C, Newville J, Maxwell J, et al. Chorioamnionitis in Rats Precipitates Extended Postnatal Inflammatory Lymphocyte Hyperreactivity. Dev Neurosci. 2019;:1-11 pubmed publisher
    Preterm birth is an important cause of perinatal brain injury (PBI)...
  25. Zhang P, Cui W, Hankey K, Gibbs A, Smith C, Taylor Howell C, et al. Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation. Health Phys. 2015;109:374-90 pubmed publisher
    ..and NHP exposed to whole thoracic lung irradiation (WTLI) or partial-body irradiation with 5% bone marrow sparing (PBI/BM5) were examined by real-time quantitative reverse transcription PCR, western blot, and immunohistochemistry...
  26. Hasanzadeh A, Pourmand M, Alizadeh A, Pourmand G. Prevalence and significance of fluoroquinolone-resistant bacteria carriage in patients undergoing transrectal ultrasound prostate biopsy. Urol J. 2017;14:3085-3090 pubmed
    ..Moreover, after prostate biopsy, blood and urine samples were collected from patients with post-biopsy infection (PBI) during 30days of follow up. In total, 73 (46...
  27. Duan H, Yu S, Liu S, Zhang H. An inorganic-organic hybrid crystal with a two-step dielectric response and thermochromic luminescence. Dalton Trans. 2017;46:2220-2227 pubmed publisher
    An iodoplumbate-based hybrid crystal [C2-Apy][PbI3] (1) (C2-Apy+ = 1-ethyl-4-aminopyridinium) was synthesized and characterized structurally...
  28. Kojima M, Tamoto A, Aratani N, Yamada H. Rearrangement of an aniline linked perylene bisimide under acidic conditions and visible to near-infrared emission from the intramolecular charge-transfer state of its fused derivatives. Chem Commun (Camb). 2017;53:5698-5701 pubmed publisher
    ..During this research, we found an unexpected rearrangement reaction on the PBI core for the first time...
  29. Siriwardena S, Chen K, Bhagwat A. Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases. Chem Rev. 2016;116:12688-12710 pubmed publisher
    ..Members of the APOBEC3 subfamily in humans (APOBEC3A, APOBEC3B, APOBEC3C, APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H) inhibit infections of viruses such as HIV-1, HBV, and HCV, and ..
  30. Zhang Z, Chen C, Ma L, Yu Q, Li S, Abbasi B, et al. Plk1 is essential for proper chromosome segregation during meiosis I/meiosis II transition in pig oocytes. Reprod Biol Endocrinol. 2017;15:69 pubmed publisher
    ..GSK461364 treatment significantly blocked the first polar body (pbI) emission in a dose-dependent manner and resulted in a failure of meiotic maturation, with a larger percentage of ..
  31. Mamun A, Ava T, Jeong H, Jeong M, Namkoong G. A deconvoluted PL approach to probe the charge carrier dynamics of the grain interior and grain boundary of a perovskite film for perovskite solar cell applications. Phys Chem Chem Phys. 2017;19:9143-9148 pubmed publisher
    ..approach capable of probing the grain interior (GI) and grain boundary (GB) of a CH3NH3PbI3-xClx perovskite thin film...
  32. Ma C, Leng C, Ji Y, Wei X, Sun K, Tang L, et al. 2D/3D perovskite hybrids as moisture-tolerant and efficient light absorbers for solar cells. Nanoscale. 2016;8:18309-18314 pubmed
    ..In this paper, the development of 2D/3D perovskite hybrids (CA2PbI4/MAPbIxCl3-x) was firstly demonstrated to be a reliable method to combine their ..
  33. Lang F, Nickel N, Bundesmann J, Seidel S, Denker A, Albrecht S, et al. Radiation Hardness and Self-Healing of Perovskite Solar Cells. Adv Mater. 2016;28:8726-8731 pubmed publisher
    The radiation hardness of CH3 NH3 PbI3 -based solar cells is evaluated from in situ measurements during high-energy proton irradiation...
  34. Radtke M, Langenbruch A, Jacobi A, Schaarschmidt M, Augustin M. Patient benefits in the treatment of psoriasis: long-term outcomes in German routine care 2007-2014. J Eur Acad Dermatol Venereol. 2016;30:1829-1833 pubmed publisher
    ..Outcomes assessment using the Patient Benefit Index (PBI) in nationwide psoriasis surveys comparing health care in 2007 and 2014...
  35. Sato K, Mizuno Y, Fuchikami H, Kato M, Shimo T, Kubota J, et al. Impact of young age on local control after partial breast irradiation in Japanese patients with early stage breast cancer. Breast Cancer. 2017;24:79-85 pubmed publisher
    Partial breast irradiation (PBI) is an alternative to whole breast irradiation (WBI) for breast-conserving therapy (BCT)...
  36. Chao L, Tai T, Chen Y, Lin P, Fu Y. Fabrication of CH?NH?PbI?/PVP Composite Fibers via Electrospinning and Deposition. Materials (Basel). 2015;8:5467-5478 pubmed publisher
    In our study, one-dimensional PbI?/polyvinylpyrrolidone (PVP) composition fibers have been prepared by using PbI? and PVP as precursors dissolved in N,N-dimethylformamide via a electrospinning process...
  37. Bishop J, Mohamad D, Wong Stringer M, Smith A, Lidzey D. Spray-cast multilayer perovskite solar cells with an active-area of 1.5 cm2. Sci Rep. 2017;7:7962 pubmed publisher
    ..conditions to sequentially deposit compact-TiO2, mesoporous-TiO2, CH3NH3PbI(3-x)Clx perovskite and doped spiro-OMeTAD layers, creating a mesoporous standard architecture ..
  38. Shang C, Wang L, An Y, Chen P, Chang X, Qi Y, et al. Langmuir-Blodgett films of perylene bisimide derivatives and fluorescent recognition of diamines. Phys Chem Chem Phys. 2017;19:23898-23904 pubmed publisher
    ..In this work, an electron-poor fluorophore, perylene bisimide (PBI), was modified with hydrophilic residues at its bay positions, resulting in an amphiphilic derivative, PEBBO...
  39. Schmalz G, Kiehl K, Schmickler J, Rinke S, Schmidt J, Krause F, et al. No difference between manual and different power toothbrushes with and without specific instructions in young, oral healthy adults-results of a randomized clinical trial. Clin Oral Investig. 2018;22:1147-1155 pubmed publisher
    ..Index (QHI) and Marginal Plaque Index (MPI) as well as inflammation indices including Papilla Bleeding Index (PBI) and Gingival Index (GI) were assessed...
  40. Ko Y, Choi W, Yun Y, Jun Y. A PbI2-xClx seed layer for obtaining efficient planar-heterojunction perovskite solar cells via an interdiffusion process. Nanoscale. 2017;9:9396-9403 pubmed publisher
    Despite the previous reports on the fabrication of CH3NH3PbI3-xClx films via sequential deposition, the positioning and formation of PbI2 in MAPbI3-xClx ..
  41. Chen C, Zhang W, Ye Q, Fu D. Lead-free Single-molecule Switching Material with Electric, Optical, Thermal Triple Controllable Multifunction Based on Perovskite-like Crystal and Flexible Thin Film. Sci Rep. 2017;7:12493 pubmed publisher
    With the flourishing development of star molecule (CH3NH3)PbI3, organic-inorganic perovskites with multifunction and flexibility have become a worldwide focus...
  42. Gagnon L, Leduc M, Thibodeau J, Zhang M, Grouix B, Sarra Bournet F, et al. A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84. Am J Pathol. 2018;188:1132-1148 pubmed publisher
    ..Using PBI-4050 (3-pentylbenzeneacetic acid sodium salt), a synthetic analog of a medium-chain fatty acid that displays ..
  43. De Maio F, Rocco C, Aulicino P, Bologna R, Mangano A, Sen L. APOBEC3-mediated editing in HIV type 1 from pediatric patients and its association with APOBEC3G/CUL5 polymorphisms and Vif variability. AIDS Res Hum Retroviruses. 2012;28:619-27 pubmed publisher
    ..Thus, our findings suggest that APOBEC3-mediated editing of HIV-1 could be modulated by host and virus genetic characteristics in the context of pediatric infection. ..
  44. Marin M, Golem S, Rose K, Kozak S, Kabat D. Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism. J Virol. 2008;82:987-98 pubmed
    ..Although the APOBEC3 paralogs A3A, A3B, and A3C have weaker anti-HIV-1 activities and are only partially degraded by Vif(IIIB), we found that Vif(IIIB) induces ..
  45. Montejo J, Durán M, Del Mar Martínez M, Hilari A, Roncalli N, Vilaregut A, et al. Family Functioning and Parental Bonding During Childhood in Adults Diagnosed With ADHD. J Atten Disord. 2015;: pubmed
    ..and Cohesion Evaluation Scale short spanish version (FACES-20esp)) and the Parental Bonding Instrument (PBI)...
  46. Yun S, Zhou X, Even J, Hagfeldt A. Theoretical Treatment of CH3 NH3 PbI3 Perovskite Solar Cells. Angew Chem Int Ed Engl. 2017;56:15806-15817 pubmed publisher
    ..structural and electronic properties, defects, ionic diffusion, and shift current for CH3 NH3 PbI3 perovskite, and the effect of ionic transport on the hysteresis of current-voltage curves in PSCs...
  47. Ong M, Eilander J, Saw S, Xie Y, Meaney M, Broekman B. The influence of perceived parenting styles on socio-emotional development from pre-puberty into puberty. Eur Child Adolesc Psychiatry. 2018;27:37-46 pubmed publisher
    ..Checklist (CBCL), while young adults completed the Youth Self-Report (YSR) and Parental Bonding Instrument (PBI)...
  48. Li B, Isikgor F, Coskun H, Ouyang J. The Effect of Methylammonium Iodide on the Supersaturation and Interfacial Energy of the Crystallization of Methylammonium Lead Triiodide Single Crystals. Angew Chem Int Ed Engl. 2017;: pubmed publisher
    ..lead triiodide single crystals grown from solutions with different methylammonium iodide (MAI):lead iodide (PbI2 ) ratios were investigated...
  49. Garcia G, Palacios P, Menéndez Proupin E, Montero Alejo A, Conesa J, Wahnón P. Influence of chromium hyperdoping on the electronic structure of CH3NH3PbI3 perovskite: a first-principles insight. Sci Rep. 2018;8:2511 pubmed publisher
    ..as its effect on the absorption features of Organic-inorganic hybrid halide perovskites CH3NH3PbI3 (MAPI)...
  50. Trovo M, Avanzo M, Vinante L, Furlan C, Fiorica F, Perin T, et al. Seven fractions to deliver partial breast irradiation: the toxicity is Low. Radiat Oncol. 2017;12:86 pubmed publisher
    ..toxicity and clinical outcome, in breast cancer patients treated with external beam partial breast irradiation (PBI) consisting of 35 Gy in 7 daily fractions (5 Gy/fraction)...
  51. Herrera Ruiz M, López Rodríguez R, Trejo Tapia G, Domínguez Mendoza B, González Cortazar M, Tortoriello J, et al. A new furofuran lignan diglycoside and other secondary metabolites from the antidepressant extract of Castilleja tenuiflora Benth. Molecules. 2015;20:13127-43 pubmed publisher
    ..and an increment in the latency and duration of the hypnosis, induced by administration of sodium pentobarbital (Pbi, 40 mg/kg, i.p.)...
  52. Shan W, Saidi W. Segregation of Native Defects to the Grain Boundaries in Methylammonium Lead Iodide Perovskite. J Phys Chem Lett. 2017;: pubmed publisher
    ..and bi-crystalline MAPbI3 with ?5-(210) GB, we find respectively that the p-type antisite defects MAI and PbI, where I substitutes for MA or Pb, introduce deep levels and both are relatively stable under I-rich conditions...
  53. Chen Z, Su S. Dual Competing Photovoltaic Supply Chains: A Social Welfare Maximization Perspective. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..Several subsidy policies such as shared solar energy arrangements and performance-based incentive (PBI) are proposed to integrate the market users and the PV supply chains...
  54. Yellowhair T, Noor S, Maxwell J, Anstine C, Oppong A, Robinson S, et al. Preclinical chorioamnionitis dysregulates CXCL1/CXCR2 signaling throughout the placental-fetal-brain axis. Exp Neurol. 2018;301:110-119 pubmed publisher
    In the United States, perinatal brain injury (PBI) is a major cause of infant mortality and childhood disability...
  55. Guo Z, Wan Y, Yang M, Snaider J, Zhu K, Huang L. Long-range hot-carrier transport in hybrid perovskites visualized by ultrafast microscopy. Science. 2017;356:59-62 pubmed publisher
    ..We report direct visualization of hot-carrier migration in methylammonium lead iodide (CH3NH3PbI3) thin films by ultrafast transient absorption microscopy, demonstrating three distinct transport ..
  56. Zu F, Amsalem P, Ralaiarisoa M, Schultz T, Schlesinger R, Koch N. Surface State Density Determines the Energy Level Alignment at Hybrid Perovskite/Electron Acceptors Interfaces. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    ..reduced lead (Pb0) directly impact the energy level alignment at perovskite (CH3NH3PbI3-xClx) and molecular electron acceptor layer interfaces using photoelectron spectroscopy...
  57. Frisenda R, Island J, Lado J, Giovanelli E, Gant P, Nagler P, et al. Characterization of highly crystalline lead iodide nanosheets prepared by room-temperature solution processing. Nanotechnology. 2017;: pubmed publisher
    ..In this article we demonstrate an easy way to synthesize ultrathin, highly crystalline flakes of PbI<sub>2</sub> by precipitation from a solution in water...
  58. You S, Bi S, Huang J, Jia Q, Yuan Y, Xia Y, et al. Additive Enhanced Crystallization of Solution-Process for Planar Perovskite Solar Cells with Efficiency Exceeding 19. Chemistry. 2017;: pubmed publisher
    ..In addition, the unencapsulated PSCs retained high output for up to 40 days in air at room temperature, indicating the stability of PSCs. These results might provide a new avenue for manufacturing high efficiency and high stability PSCs...
  59. Pery E, Rajendran K, Brazier A, Gabuzda D. Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif. J Virol. 2009;83:2374-81 pubmed publisher
    ..In HIV-1-infected CD4+ T cells, the viral accessory protein Vif binds to APOBEC3G (A3G), APOBEC3F (A3F), and APOBEC3C (A3C) and targets these proteins for polyubiquitination by forming an E3 ubiquitin ligase with cullin 5...
  60. Harris R. Enhancing immunity to HIV through APOBEC. Nat Biotechnol. 2008;26:1089-90 pubmed publisher
  61. Samuel C. Introduction to thematic minireview series: Understanding human immunodeficiency virus-host interactions at the biochemical level. J Biol Chem. 2012;287:40838-40 pubmed publisher
  62. Adli H, Harada T, Nakanishi S, Ikeda S. Effects of TiCl4 treatment on the structural and electrochemical properties of a porous TiO2 layer in CH3NH3PbI3 perovskite solar cells. Phys Chem Chem Phys. 2017;19:26898-26905 pubmed publisher
    ..investigated in order to obtain an optimum pTiO2 layer for use in CH3NH3PbI3 perovskite solar cells...
  63. Leblanc A, Mercier N, Allain M, Dittmer J, Fernandez V, Pauporte T. Lead- and Iodide-Deficient (CH3 NH3 )PbI3 (d-MAPI): The Bridge between 2D and 3D Hybrid Perovskites. Angew Chem Int Ed Engl. 2017;: pubmed publisher
    ..promising materials for optoelectronic applications, particularly the 3D compound (CH3 NH3 )PbI3 (MAPI)...
  64. Tang Z, Xu Z, Zhang D, Hu S, Lau W, Liu L. Enhanced optical absorption via cation doping hybrid lead iodine perovskites. Sci Rep. 2017;7:7843 pubmed publisher
    ..properties of cation (Bi, Sn, and TI) doped tetragonal formamidinium lead iodine CH(NH2)2PbI3 (FAPbI3) are studied by first-principles calculations...
  65. Serpetzoglou E, Konidakis I, Kakavelakis G, Maksudov T, Kymakis E, Stratakis E. Improved Carrier Transport in Perovskite Solar Cells Probed by Femtosecond Transient Absorption Spectroscopy. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    ..It is concluded that TAS is a benchmark technique for the understanding of the carrier transport mechanisms in PSCs and constitutes a figure-of-merit tool towards their efficiency improvement...
  66. Miller J, Campbell E, Dick B, Rheingold A, Zhang C, Liu X, et al. Structures of a Complex Hydrazinium Lead Iodide, (N2H5)15Pb3I21, Possessing [Pb2I9]5-, [PbI6]4-, and I- Ions and ?- and ?-(N2H5)PbI3. Chemistry. 2017;: pubmed publisher
    ..The structure of ?- and ?-(N2H5)PbI3 possess parallel ribbons of Pb2I4 and chains of PbI2, respectively. (N2H5)15Pb3I21 has a band gap of 2.34 eV, and both ?- and ?-(N2H5)PbI3 have a 2.70 eV band gap...
  67. Shkir M, Alfaify S. Tailoring the structural, morphological, optical and dielectric properties of lead iodide through Nd3+ doping. Sci Rep. 2017;7:16091 pubmed publisher
    Hexagonal single crystal nanosheets of Nd3+ doped PbI2 were effortlessly synthesized via microwave-assisted technique under a power of 700?W and in a duration of 15?minutes with a homogeneous morphology...
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    ..Today's best devices, based on a three-dimensional perovskite structure of corner-sharing PbI6 octahedra, are unstable, toxic, and display hysteresis in current-voltage measurements...
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    ..The iridium(iii) complex 9 [Ir(pbi)2(5,5-dmbpy)]PF6 (where pbi = 2-phenyl-1H-benzo[d]imidazole; 5,5-dmbpy = 5,5'-..
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    ..ether as a dripping solvent to obtain extremely uniform and highly crystalline CH3NH3PbI3 perovskite films...
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    ..These results demonstrate that HIV-1 Vpr leads to the induction of ISGs and expand the current understanding of the function of Vpr and its role in HIV-1 immune pathogenesis. ..
  75. Zhu W, Chen D, Zhou L, Zhang C, Chang J, Lin Z, et al. Intermediate Phase Intermolecular Exchange Triggered Defect Elimination in CH3NH3PbI3 toward Room-Temperature Fabrication of Efficient Perovskite Solar Cells. ACS Appl Mater Interfaces. 2017;: pubmed publisher
    ..one-step spin-coating method has been widely used to produce full-coverage CH3NH3PbI3 films for perovskite solar cells by forming an intermediate phase...
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    We have investigated the fundamental photophysical properties of surface-bound perylene bisimide (PBI) molecules in a solution-phase at the single-molecule level...
  77. Horn A, Klawitter S, Held U, Berger A, Vasudevan A, Bock A, et al. Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity. Nucleic Acids Res. 2014;42:396-416 pubmed publisher
    ..We set out to uncover the mechanism of APOBEC3C (A3C)-mediated L1 inhibition and found that it is deaminase independent, requires an intact dimerization site and ..
  78. Yang J, Zhang P, Wei S. Band Structure Engineering of Cs2AgBiBr6 Perovskite through Order-Disordered Transition: A First Principle Study. J Phys Chem Lett. 2017;: pubmed publisher
    ..Our study, therefore, provides a novel approach to carry out band structure engineering in the mixed perovskites for optoelectronic applications...
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    ..Planar perovskite solar cells with conventional materials (CH3NH3PbI3-xClx) were fabricated...
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    ..hemiiodine], {[CuICuIIPbI5(C12H8N2)2]·0...
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    Recently developed stereotactic partial breast irradiation (S-PBI) allows delivery of a high biologically potent dose to the target while sparing adjacent critical organs and normal tissue...
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    ..Moreover, the efficient one-dimensional (1D) transport paths for electrons and multiple absorption of light, which are generated in 3-D architecture, were beneficial to realize the decent power conversion efficiency...
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    A metal-organic hybrid perovskite (CH3NH3PbI3) with three-dimensional framework of metal-halide octahedra has been reported as a low-cost, solution-processable absorber for a thin-film solar cell with a ..
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    ..We focussed on proteins depleted with similar kinetics to APOBEC3C, and found the viral accessory protein Vif to be necessary and sufficient for CUL5-dependent proteasomal ..
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    ..HepG2 cells were cotransfected with HBV expression plasmid and the plasmid encoding fusion protein of either Core-A3C or Core-humanized renilla GFP (hrGFP). Core-A3C had substantial effect on HBV DNA levels...
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    ..SnO?:F)-glass (or PET-ITO (In?O?·(SnO?) (ITO)) on, polyethylene terephthalate (PET)/ZnAc seed layer/ZnO NWs/CH?NH?PbI?/Spiro-OMeTAD/Au...
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    ..High-resolution structures of the catalytic CD2 of A3G and A3F as well as of the single CD proteins A3A and A3C have been published recently...
  89. Besra N, Pal S, Das B, Chattopadhyay K. Perovskites beyond photovoltaics: field emission from morphology-tailored nanostructured methylammonium lead triiodide. Phys Chem Chem Phys. 2017;19:26708-26717 pubmed publisher
    Herein, methylammonium lead triiodide (CH3NH3PbI3) nanorods and nanocrystals were prepared by a facile room-temperature wet chemical method via simple variation of the synthesis parameters...
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    ..Here, this study systematically investigates the effect of precise stoichiometry, especially the PbI2 contents on device performance including efficiency, hysteresis and stability...