AMH

Summary

Gene Symbol: AMH
Description: anti-Mullerian hormone
Alias: MIF, MIS, muellerian-inhibiting factor, Mullerian inhibiting factor, Mullerian inhibiting substance, anti-Muellerian hormone, muellerian-inhibiting substance
Species: human
Products:     AMH

Top Publications

  1. Broer S, Mol B, Hendriks D, Broekmans F. The role of antimullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count. Fertil Steril. 2009;91:705-14 pubmed publisher
    To assess the value of antimullerian hormone (AMH) as a test to predict poor ovarian response and pregnancy occurrence after IVF and to compare it with the performance of the antral follicle count (AFC)...
  2. van Rooij I, Broekmans F, te Velde E, Fauser B, Bancsi L, de Jong F, et al. Serum anti-Müllerian hormone levels: a novel measure of ovarian reserve. Hum Reprod. 2002;17:3065-71 pubmed
    Anti-Müllerian hormone (AMH) is produced by the granulosa cells of preantral and small antral follicles and its levels can be assessed in serum...
  3. Woo H, Kim K, Rhee E, Park H, Lee M. Differences of the association of anti-Müllerian hormone with clinical or biochemical characteristics between women with and without polycystic ovary syndrome. Endocr J. 2012;59:781-90 pubmed
    The aim of the present study was to compare the associations of anti-Müllerian hormone (AMH) with clinical or biochemical characteristics between women with and without polycystic ovary syndrome (PCOS)...
  4. La Marca A, Stabile G, Artenisio A, Volpe A. Serum anti-Mullerian hormone throughout the human menstrual cycle. Hum Reprod. 2006;21:3103-7 pubmed
    The anti-Mullerian hormone (AMH) is a member of the transforming growth factor (TGF) superfamily. In women, AMH serum levels can be almost undetectable at birth, with a subtle increase noted after puberty...
  5. di Clemente N, Jamin S, Lugovskoy A, Carmillo P, Ehrenfels C, Picard J, et al. Processing of anti-mullerian hormone regulates receptor activation by a mechanism distinct from TGF-beta. Mol Endocrinol. 2010;24:2193-206 pubmed publisher
    ..Here we show that anti-Müllerian hormone (AMH), a TGF-? family ligand involved in reproductive development, must be cleaved to bind its type II receptor (AMHRII),..
  6. Barad D, Weghofer A, Gleicher N. Comparing anti-Müllerian hormone (AMH) and follicle-stimulating hormone (FSH) as predictors of ovarian function. Fertil Steril. 2009;91:1553-5 pubmed publisher
    We compared predictive values of anti-Müllerian hormone (AMH) and baseline FSH with respect to IVF cycle outcomes based on oocyte numbers retrieved and number of clinical pregnancies established...
  7. Kevenaar M, Themmen A, Rivadeneira F, Uitterlinden A, Laven J, van Schoor N, et al. A polymorphism in the AMH type II receptor gene is associated with age at menopause in interaction with parity. Hum Reprod. 2007;22:2382-8 pubmed
    Anti-Müllerian hormone (AMH) inhibits primordial follicle recruitment in the mouse ovary. We hypothesize that in women AMH signaling also regulates the usage of the primordial follicle pool and hence influences the onset of menopause...
  8. Andersen C, Lossl K. Increased intrafollicular androgen levels affect human granulosa cell secretion of anti-Müllerian hormone and inhibin-B. Fertil Steril. 2008;89:1760-5 pubmed
    To evaluate whether the follicular fluid concentrations of anti-müllerian hormone (AMH), inhibin-B, and P become affected by androgen priming before controlled ovarian hyperstimulation and IVF/intracytoplasmic sperm injection (ICSI) ..
  9. Hart R, Doherty D, Norman R, Franks S, Dickinson J, Hickey M, et al. Serum antimullerian hormone (AMH) levels are elevated in adolescent girls with polycystic ovaries and the polycystic ovarian syndrome (PCOS). Fertil Steril. 2010;94:1118-21 pubmed publisher
    ..study set out to determine if the investigators could derive a threshold value of antimullerian hormone (AMH) that would predict its presence according to two internationally recognized definitions using a simple measurement,..

More Information

Publications85

  1. Lem A, Boonstra V, Renes J, Breukhoven P, de Jong F, Laven J, et al. Anti-Mullerian hormone in short girls born small for gestational age and the effect of growth hormone treatment. Hum Reprod. 2011;26:898-903 pubmed publisher
    ..Serum anti-Müllerian hormone (AMH) is a marker of the primordial follicle pool...
  2. Kelsey T, Wright P, Nelson S, Anderson R, Wallace W. A validated model of serum anti-müllerian hormone from conception to menopause. PLoS ONE. 2011;6:e22024 pubmed publisher
    Anti-Müllerian hormone (AMH) is a product of growing ovarian follicles. The concentration of AMH in blood may also reflect the non-growing follicle (NGF) population, i.e...
  3. Sahmay S, Usta T, Erel C, Imamoğlu M, Kucuk M, Atakul N, et al. Is there any correlation between amh and obesity in premenopausal women?. Arch Gynecol Obstet. 2012;286:661-5 pubmed publisher
    ..No statistically significant correlation was found between Anti Müllerian Hormone (AMH) levels and BMI levels in either group (P > 0.05)...
  4. Fanchin R, Schonauer L, Righini C, Guibourdenche J, Frydman R, Taieb J. Serum anti-Müllerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3. Hum Reprod. 2003;18:323-7 pubmed
    The study aim was to compare the relationship between serum anti-Müllerian hormone (AMH) levels and other markers of ovarian function with early antral follicle count on day 3. A total of 75 infertile women was studied prospectively...
  5. Anderson R, Rosendahl M, Kelsey T, Cameron D. Pretreatment anti-Müllerian hormone predicts for loss of ovarian function after chemotherapy for early breast cancer. Eur J Cancer. 2013;49:3404-11 pubmed publisher
    ..5]) with eBC were recruited before any treatment. Pretreatment ovarian reserve markers (anti-Müllerian hormone [AMH], follicle-stimulating hormone [FSH], inhibin B) were analysed in relation to ovarian status at 2 years...
  6. Josso N, di Clemente N, Gouédard L. Anti-Müllerian hormone and its receptors. Mol Cell Endocrinol. 2001;179:25-32 pubmed
    Anti-Müllerian hormone (AMH), a member of the transforming growth factor-beta family, is an important factor of male sex differentiation. It is produced by Sertoli cells from the time of fetal sex differentiation to puberty...
  7. van Dorp W, van den Heuvel Eibrink M, de Vries A, Pluijm S, Visser J, Pieters R, et al. Decreased serum anti-Müllerian hormone levels in girls with newly diagnosed cancer. Hum Reprod. 2014;29:337-42 pubmed publisher
    Are anti-Müllerian hormone (AMH) levels reduced in girls with newly diagnosed cancer before the start of treatment? AMH levels are already compromised in girls at the time of cancer diagnosis compared with healthy girls...
  8. Aksglaede L, Sørensen K, Boas M, Mouritsen A, Hagen C, Jensen R, et al. Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years. J Clin Endocrinol Metab. 2010;95:5357-64 pubmed publisher
    Anti-Müllerian hormone (AMH), which is secreted by immature Sertoli cells, triggers the involution of the fetal Müllerian ducts...
  9. Hagen C, Aksglaede L, Sørensen K, Main K, Boas M, Cleemann L, et al. Serum levels of anti-Müllerian hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 Turner syndrome patients. J Clin Endocrinol Metab. 2010;95:5003-10 pubmed publisher
    In adult women, anti-Müllerian hormone (AMH) is related to the ovarian follicle pool. Little is known about AMH in girls.
  10. Eilsø Nielsen M, Rasmussen I, Fukuda M, Westergaard L, Yding Andersen C. Concentrations of anti-Müllerian hormone in fluid from small human antral follicles show a negative correlation with CYP19 mRNA expression in the corresponding granulosa cells. Mol Hum Reprod. 2010;16:637-43 pubmed publisher
    ..The FF was used to evaluate the intrafollicular concentrations of anti-Müllerian hormone (AMH), inhibin-B, estradiol, progesterone, androstenedione and testosterone...
  11. Nelson S, Stewart F, Fleming R, Freeman D. Longitudinal assessment of antimüllerian hormone during pregnancy-relationship with maternal adiposity, insulin, and adiponectin. Fertil Steril. 2010;93:1356-8 pubmed publisher
    ..pregnancy cohort the influence of advancing gestation and baseline maternal adiposity on antimüllerian hormone (AMH) and determined whether maternal hormones (insulin, leptin, adiponectin, E(2), and sex hormone-binding globulin) ..
  12. Mishina Y, Rey R, Finegold M, Matzuk M, Josso N, Cate R, et al. Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation. Genes Dev. 1996;10:2577-87 pubmed
    Müllerian-inhibiting substance (MIS) is a member of the transforming growth factor-beta (TGF-beta) gene family. MIS expression in males causes the regression of the Müllerian ducts, an essential process in male sexual differentiation...
  13. Wunder D, Guibourdenche J, Birkhäuser M, Bersinger N. Anti-Müllerian hormone and inhibin B as predictors of pregnancy after treatment by in vitro fertilization/intracytoplasmic sperm injection. Fertil Steril. 2008;90:2203-10 pubmed publisher
    To evaluate anti-Müllerian hormone (AMH) as a marker of reproductive outcome after IVF/intracytoplasmic sperm injection (ICSI). Longitudinal study. University hospital. Two hundred seventy-six consecutive women undergoing IVF/ICSI...
  14. Pigny P, Merlen E, Robert Y, Cortet Rudelli C, Decanter C, Jonard S, et al. Elevated serum level of anti-mullerian hormone in patients with polycystic ovary syndrome: relationship to the ovarian follicle excess and to the follicular arrest. J Clin Endocrinol Metab. 2003;88:5957-62 pubmed
    The serum level of anti-Mullerian hormone (AMH), a product from granulosa cells involved in follicle growth, has been shown to correlate tightly with the small antral follicle number (FN) at ultrasonography (U/S) in women who do not have ..
  15. Josso N, Picard J, Rey R, di Clemente N. Testicular anti-Müllerian hormone: history, genetics, regulation and clinical applications. Pediatr Endocrinol Rev. 2006;3:347-58 pubmed
    Anti-Müllerian hormone (AMH), also called MUllerian inhibiting substance (MIS) is a product of supporting gonadal Sertoli and granulosa cells...
  16. Pigny P, Jonard S, Robert Y, Dewailly D. Serum anti-Mullerian hormone as a surrogate for antral follicle count for definition of the polycystic ovary syndrome. J Clin Endocrinol Metab. 2006;91:941-5 pubmed
    ..The aim of our study was to check whether anti-Müllerian hormone (AMH) measurement in the serum could be a surrogate for antral follicle count in the diagnostic criteria of PCOS...
  17. Mulders A, Laven J, Eijkemans M, de Jong F, Themmen A, Fauser B. Changes in anti-Müllerian hormone serum concentrations over time suggest delayed ovarian ageing in normogonadotrophic anovulatory infertility. Hum Reprod. 2004;19:2036-42 pubmed
    Anti-Müllerian hormone (AMH), produced by growing pre-antral and early antral ovarian follicles, has been shown to be a useful marker for ovarian ageing...
  18. Cate R, Mattaliano R, Hession C, Tizard R, Farber N, Cheung A, et al. Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells. Cell. 1986;45:685-98 pubmed
    We have isolated the bovine and human genes for Müllerian inhibiting substance (MIS), a testicular glycoprotein that causes regression of the Müllerian duct during development of the male embryo...
  19. Arce J, La Marca A, Mirner Klein B, Nyboe Andersen A, Fleming R. Antimüllerian hormone in gonadotropin releasing-hormone antagonist cycles: prediction of ovarian response and cumulative treatment outcome in good-prognosis patients. Fertil Steril. 2013;99:1644-53 pubmed publisher
    To assess the relationships between serum antimüllerian hormone (AMH) and ovarian response and treatment outcomes in good-prognosis patients undergoing controlled ovarian stimulation using a gonadotropin-releasing hormone (GnRH) ..
  20. Weenen C, Laven J, von Bergh A, Cranfield M, Groome N, Visser J, et al. Anti-Müllerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod. 2004;10:77-83 pubmed
    Anti-Müllerian hormone (AMH) is a member of the transforming growth factor-beta superfamily, which plays an important role in both ovarian primordial follicle recruitment and dominant follicle selection in mice...
  21. Villarroel C, Merino P, Lopez P, Eyzaguirre F, Van Velzen A, Iniguez G, et al. Polycystic ovarian morphology in adolescents with regular menstrual cycles is associated with elevated anti-Mullerian hormone. Hum Reprod. 2011;26:2861-8 pubmed publisher
    ..The aim of this study was to determine the relationship between PCOM and anti-Müllerian hormone (AMH), inhibin B, testosterone and insulin levels in healthy girls during the second decade of life...
  22. Buyuk E, Seifer D, Illions E, Grazi R, Lieman H. Elevated body mass index is associated with lower serum anti-mullerian hormone levels in infertile women with diminished ovarian reserve but not with normal ovarian reserve. Fertil Steril. 2011;95:2364-8 pubmed publisher
    ..Diminished ovarian reserve (DOR) was defined as day 3 FSH>10 IU/L. None. Random serum antimullerian hormone (AMH) levels and number of oocytes retrieved during assisted reproductive technology cycle...
  23. Buyuk E, Seifer D, Younger J, Grazi R, Lieman H. Random anti-Müllerian hormone (AMH) is a predictor of ovarian response in women with elevated baseline early follicular follicle-stimulating hormone levels. Fertil Steril. 2011;95:2369-72 pubmed publisher
    To investigate the utility of random anti-Müllerian hormone (AMH) in assessing ovarian response among women with diminished ovarian reserve (DOR) diagnosed by elevated early follicular-phase FSH levels. Retrospective study...
  24. Belville C, Jamin S, Picard J, Josso N, di Clemente N. Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line. Oncogene. 2005;24:4984-92 pubmed
    Anti-Müllerian hormone (AMH) is a member of the transforming growth factor-beta family responsible for regression of Müllerian ducts during male sexual differentiation and for regulation of gonadal steroidogenesis...
  25. Seifer D, MacLaughlin D. Mullerian Inhibiting Substance is an ovarian growth factor of emerging clinical significance. Fertil Steril. 2007;88:539-46 pubmed
    To examine Mullerian Inhibiting Substance (MIS) as an emerging diagnostic marker of ovarian function...
  26. Wang J, Dicken C, Lustbader J, Tortoriello D. Evidence for a Müllerian-inhibiting substance autocrine/paracrine system in adult human endometrium. Fertil Steril. 2009;91:1195-203 pubmed publisher
    To determine if adult human endometrium possesses an intact müllerian-inhibiting substance (MIS) signal transduction system and, if so, whether MIS can modulate endometrial cell viability...
  27. Sowers M, Eyvazzadeh A, McConnell D, Yosef M, Jannausch M, Zhang D, et al. Anti-mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition. J Clin Endocrinol Metab. 2008;93:3478-83 pubmed publisher
    The objective of the study was to determine whether anti-Mullerian hormone (AMH) and inhibin B are viable endocrine biomarkers for framing the menopause transition from initiation to the final menstrual period (FMP)...
  28. Laven J, Mulders A, Visser J, Themmen A, de Jong F, Fauser B. Anti-Müllerian hormone serum concentrations in normoovulatory and anovulatory women of reproductive age. J Clin Endocrinol Metab. 2004;89:318-23 pubmed
    Anti-Müllerian hormone (AMH) concentrations correlate with the number of antral follicles as well as age and constitute an endocrine marker for ovarian aging...
  29. Cheng C, Zhou Y, Li H, Xiong T, Li S, Bi Y, et al. Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma. Am J Hum Genet. 2016;98:256-74 pubmed publisher
    ..Moreover, chromothripsis, kataegis, and breakage-fusion-bridge (BFB) were identified as contributing to locally mis-arranged chromosomes that occurred in 55% of ESCCs...
  30. Luo Z, Rao H, Huang D, Li G, Liu C, Dong S, et al. [Comparison of minimally invasive using a tubular retraction system versus open transforaminal lumbar interbody fusion for the treatment of lumbar degenerative diseases]. Zhonghua Yi Xue Za Zhi. 2015;95:2681-5 pubmed
    To compare the clinical effect of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) using a tubular retraction system with traditional transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar ..
  31. Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, et al. Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS ONE. 2017;12:e0179591 pubmed publisher
    ..The findings presented here may help elucidate the molecular mechanisms underlying derangements of lipoic acid biosynthesis. ..
  32. Huang P, Wang Y, Xu J, Xiao B, Liu J, Che L, et al. Minimally invasive unilateral pedicle screws and a translaminar facet screw fixation and interbody fusion for treatment of single-segment lower lumbar vertebral disease: surgical technique and preliminary clinical results. J Orthop Surg Res. 2017;12:117 pubmed publisher
    ..The outcomes of minimally invasive TLIF (MIS TLIF) are similar to the good outcomes of open TLIF, with the additional benefits of reducing iatrogenic injury, ..
  33. Pierre A, Taieb J, Giton F, Grynberg M, Touleimat S, El Hachem H, et al. Dysregulation of the Anti-Müllerian Hormone System by Steroids in Women With Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2017;102:3970-3978 pubmed publisher
    Anti-Müllerian hormone (AMH) and AMH type II receptor (AMHR2) are overexpressed in granulosa cells (GCs) from women with polycystic ovary syndrome (PCOS), the most common cause of female infertility...
  34. Zhou Y, Yang Q, Zhong X, Tang H, Deng M, Ma J, et al. Alternative splicing results in a lack of starch synthase IIa-D in Chinese wheat landrace. Genome. 2018;61:201-208 pubmed publisher
    ..Four cDNA types with mis-spliced isoforms were subsequently detected through amplification of TaSSIIa-D cDNAs...
  35. Kok T, Wasiel A, Dekker F, Poelarends G, Cool R. High yield production of human invariant chain CD74 constructs fused to solubility-enhancing peptides and characterization of their MIF-binding capacities. Protein Expr Purif. 2018;148:46-53 pubmed publisher
    ..It is also part of a receptor complex for macrophage migration inhibitory factor (MIF), and participates in inflammatory signaling...
  36. Wang J, Pan L, Wu S, Lu L, Xu Y, Zhu Y, et al. Recent Advances on Endocrine Disrupting Effects of UV Filters. Int J Environ Res Public Health. 2016;13: pubmed publisher
    ..With growing usage and mis-disposition of UV filters, they currently represent a new class of contaminants of emerging concern with ..
  37. Andersen J, Herning H, Witczak O, Haugen T. Anti-Müllerian hormone in seminal plasma and serum: association with sperm count and sperm motility. Hum Reprod. 2016;31:1662-7 pubmed publisher
    Is anti-Müllerian hormone (AMH) in seminal plasma and serum associated with sperm count and sperm motility? AMH in seminal plasma is positively associated with sperm concentration, total sperm count, and progressive sperm motility, ..
  38. Ding C, Zou Q, Wang F, Wu H, Chen R, Lv J, et al. Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. Stem Cell Res Ther. 2018;9:55 pubmed publisher
    ..immunosorbent assay was used to detect the serum levels of the sex hormones estradiol (E2), anti-mullerian hormone (AMH), and follicle-stimulating hormone (FSH)...
  39. Bonaterra G, Then H, Oezel L, Schwarzbach H, Ocker M, Thieme K, et al. Morphological Alterations in Gastrocnemius and Soleus Muscles in Male and Female Mice in a Fibromyalgia Model. PLoS ONE. 2016;11:e0151116 pubmed publisher
    ..However, this loss in male ICS mice was associated with an increase in gastrocnemius of the density of MIF+ (8.6%)-, MuRF+ (14.7%)-, Fbxo32+ (17.8%)-cells, a 12.1% loss of capillary contacts/muscle fiber as well as a 30...
  40. Bruschetta D, Milardi D, Trimarchi F, Di Mauro D, Valenti A, Arrigo A, et al. Muscle contracture diagnosis: the role of sonoelastography. J Sports Med Phys Fitness. 2016;56:1518-1525 pubmed
    ..This information will be useful for prognostication, post-traumatic monitoring and to detect subclinical changes in MIs even before there are changes on the routine B-mode ultrasound.
  41. Kidd S, Bonaca M, Braunwald E, De Ferrari G, Lewis B, Merlini P, et al. Universal Classification System Type of Incident Myocardial Infarction in Patients With Stable Atherosclerosis: Observations From Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)-TIMI 50. J Am Heart Assoc. 2016;5: pubmed publisher
    ..Of 1095 incident MIs, 77% were spontaneous (Type 1), with a smaller number (9.8%) of secondary MIs (Type 2)...
  42. Nakazawa K, Egorova N, Power J, Faries P, Vouyouka A. The Impact of Surgical Care Improvement Project Measures on In-Hospital Outcomes following Elective Vascular Procedures. Ann Vasc Surg. 2017;38:17-28 pubmed publisher
    ..the effect of SCIP on in-hospital surgical site infections (SSI), graft infections, VTE, myocardial infarctions (MIs), cardiac complications, mortality, and length of stay following elective major vascular surgery...
  43. De Conto E, Matte U, Bilibio J, Genro V, Souza C, Leão D, et al. Endometriosis-associated infertility: GDF-9, AMH, and AMHR2 genes polymorphisms. J Assist Reprod Genet. 2017;34:1667-1672 pubmed publisher
    ..correlation between polymorphisms in the growth differentiation factor-9 (GDF-9) gene and anti-Müllerian hormone (AMH) gene and its receptor, AMHR2, and endometriosis-associated infertility...
  44. Nieweglowska D, Hajdyla Banaś I, Pitynski K, Banas T, Grabowska O, Juszczyk G, et al. Age-related trends in anti-Mullerian hormone serum level in women with unilateral and bilateral ovarian endometriomas prior to surgery. Reprod Biol Endocrinol. 2015;13:128 pubmed publisher
    Endometriosis is a well-known cause of infertility, and the anti-Mullerian hormone (AMH) is an accepted biomarker of ovarian reserve and response to artificial reproductive technology procedures...
  45. Guo F, Ru Q, Zhang J, He S, Yu J, Zheng S, et al. Inflammation factors in hepatoblastoma and their clinical significance as diagnostic and prognostic biomarkers. J Pediatr Surg. 2017;52:1496-1502 pubmed publisher
    ..that were significantly upregulated in the tumor tissue were identified as macrophage migration inhibitory factor (MIF), chemokine (C-X-C motif) ligand 7 (CXCL7), and interleukin 25 (IL-25)...
  46. Carrarelli P, Rocha A, Belmonte G, Zupi E, Abrao M, Arcuri F, et al. Increased expression of antimüllerian hormone and its receptor in endometriosis. Fertil Steril. 2014;101:1353-8 pubmed publisher
    To evaluate antimüllerian hormone (AMH) and AMH receptor II (AMHRII) mRNA and protein expression in endometrium and in ovarian or deep lesions of women with endometriosis.
  47. Lang Muritano M, Biason Lauber A, Gitzelmann C, Belville C, Picard Y, Schoenle E. A novel mutation in the anti-müllerian hormone gene as cause of persistent müllerian duct syndrome. Eur J Pediatr. 2001;160:652-4 pubmed
    ..individuals, uterus and tubes are present because of defects of synthesis or action of anti-müllerian hormone (AMH), normally produced by the Sertoli cells of the testis...
  48. Padek M, Allen P, Erwin P, Franco M, Hammond R, Heuberger B, et al. Toward optimal implementation of cancer prevention and control programs in public health: a study protocol on mis-implementation. Implement Sci. 2018;13:49 pubmed publisher
    ..b>Mis-implementation refers to ending effective programs and policies prematurely or continuing ineffective ones...
  49. Bhatt N, Davis N, Dalton D, McDermott T, Flynn R, Thomas A, et al. Quantitative Analysis of Technological Innovation in Urology. Urology. 2018;111:230-237 pubmed publisher
    ..clusters in descending order were surgical instruments including urinary catheters, minimally invasive surgery (MIS), lasers, robotic surgery, and image guidance...
  50. Lim J, Yeong J, Lim C, Ong C, Wong S, Chew V, et al. An automated staining protocol for seven-colour immunofluorescence of human tissue sections for diagnostic and prognostic use. Pathology. 2018;50:333-341 pubmed publisher
    Multiplex immunofluorescence (mIF) allows simultaneous antibody-based detection and quantification of the expression of up to six markers, plus a nuclear counterstain, on a single tissue section...
  51. Brew O, Sullivan M. Oxygen and tissue culture affect placental gene expression. Placenta. 2017;55:13-20 pubmed publisher
    ..We uncovered sub-sets of genes that regulate response to stress, induction of apoptosis programmed cell death, mis-regulation of cell growth, proliferation, cell morphogenesis, tissue viability, and protection from apoptosis in ..
  52. Thul P, Lindskog C. The human protein atlas: A spatial map of the human proteome. Protein Sci. 2018;27:233-244 pubmed publisher
    The correct spatial distribution of proteins is vital for their function and often mis-localization or ectopic expression leads to diseases...
  53. Yi X, Lin J, Li J, Zhou Q, Han Z. Epoxyeicosatrienoic Acids are Mediated by EPHX2 Variants and may be a Predictor of Early Neurological Deterioration in Acute Minor Ischemic Stroke. J Atheroscler Thromb. 2017;24:1258-1266 pubmed publisher
    To investigatethe association of plasma epoxyeicosatrienoic acids (EETs) with early neurologic deterioration (END), and whether EETs are mediated by EPHX2 variants in patients with minor ischemic stroke (MIS).
  54. Kwon S, Kim S, Yun S, Kim D, Chae H, Kim C, et al. Decline of serum antimüllerian hormone levels after laparoscopic ovarian cystectomy in endometrioma and other benign cysts: a prospective cohort study. Fertil Steril. 2014;101:435-41 pubmed publisher
    ..Serum antimüllerian hormone (AMH) levels measured by enzyme immunoassay preoperatively and at 3 months after surgery...
  55. Liu Y, Yang C, Liu H, Sui S, Li X. Efficacy and Therapeutic Potential of Curcumin Against Sepsis-Induced Chronic Lung Injury in Male Albino Rats. J Nutr Health Aging. 2017;21:307-313 pubmed publisher
    ..Cytokines such as interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-a) and macrophage inhibitory factor (MIF) were measured in the BALF...
  56. Xu W, Mukherjee S, Ning Y, Hsu F, Zhang K. Cyclopropane fatty acid synthesis affects cell shape and acid resistance in Leishmania mexicana. Int J Parasitol. 2018;48:245-256 pubmed publisher
    ..Without the downstream sequence, the mis-localised CFAS protein cannot fully rescue the defects of cfas-...
  57. Webster K, Schach U, Ordaz A, Steinfeld J, Draper B, Siegfried K. Dmrt1 is necessary for male sexual development in zebrafish. Dev Biol. 2017;422:33-46 pubmed publisher
    ..We found that Dmrt1 is necessary for normal transcriptional regulation of the amh (anti-Müllerian hormone) and foxl2 (forkhead box L2) genes, which are thought to be important for male or female ..
  58. Harris J, Deen N, Zamani S, Hasnat M. Mitophagy and the release of inflammatory cytokines. Mitochondrion. 2018;41:2-8 pubmed publisher
    ..of inflammatory cytokines, including IL-1?, IL-1?, IL-18, type I IFN and macrophage migration inhibitory factor (MIF). Moreover, release of these cytokines can subsequently promote the release of others, including IL-23 and IL-17...
  59. Korf H, Breser L, Van Hoeck J, Godoy J, Cook D, Stijlemans B, et al. MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset. PLoS ONE. 2017;12:e0187455 pubmed publisher
    ..Here, we investigated a role for macrophage migration inhibitory factor (MIF) and its transmembrane receptor, CD74, in the progression of T1D...
  60. Choi W, Moon J, Min J, Song Y, Lee S, Ahn J, et al. Real-time detection system for tumor localization during minimally invasive surgery for gastric and colon cancer removal: In vivo feasibility study in a swine model. J Surg Oncol. 2018;117:699-706 pubmed publisher
    During minimally invasive surgery (MIS), it is impossible to directly detect marked clips around tumors via palpation...
  61. Rico C, Fabre S, Medigue C, di Clemente N, Clement F, Bontoux M, et al. Anti-mullerian hormone is an endocrine marker of ovarian gonadotropin-responsive follicles and can help to predict superovulatory responses in the cow. Biol Reprod. 2009;80:50-9 pubmed publisher
    ..This study aimed to establish whether anti-Müllerian hormone (AMH) was an endocrine marker of follicular populations in the cow, as in human, and a possible predictor of the ovarian ..
  62. Wang T, Pan B, Fu Y, Wang S, Ai Y. Design of a new haptic device and experiments in minimally invasive surgical robot. Comput Assist Surg (Abingdon). 2017;22:240-250 pubmed publisher
    ..In addition, the haptic device and a slave surgical robot for minimally invasive surgery (MIS) developed by our lab are integrated as a master-slave surgical robotic system in this paper...
  63. Somunkiran A, Yavuz T, Yucel O, Ozdemir I. Anti-Müllerian hormone levels during hormonal contraception in women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol. 2007;134:196-201 pubmed
    ..Anti-Müllerian hormone (AMH) levels are high in PCOS patients and are stable throughout the menstrual cycle in healthy subjects...
  64. Lin Q, Cai J, Lu C, Sun J, Ba H, Chen M, et al. Macrophage migration inhibitory factor levels in serum from patients with acute intracerebral hemorrhage: Potential contribution to prognosis. Clin Chim Acta. 2017;472:58-63 pubmed publisher
    Intracerebral hemorrhage (ICH) pathophysiology involves inflammation. Macrophage migration inhibition factor (MIF), a pro-inflammatory cytokine, is related to prognosis of ischemic stroke...
  65. Caglar G, Kahyaoglu I, Pabuccu R, Demirtas S, Seker R. Anti-Mullerian hormone and insulin resistance in classic phenotype lean PCOS. Arch Gynecol Obstet. 2013;288:905-10 pubmed publisher
    This study is designed to explore the correlation between AMH levels and IR in normal weight PCOS women...
  66. Weber L, Marcy H, Shen Y, Tomkovich S, Brooks K, Hilk K, et al. The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development. Exp Neurol. 2018;301:100-109 pubmed publisher
    Macrophage migration inhibitory factor (MIF) is a neurotrophic cytokine essential for inner ear hair cell (HC) development and statoacoustic ganglion (SAG) neurite outgrowth, and SAG survival in mouse, chick and zebrafish...
  67. Helm B, Willer J, Sadeghpour A, Golzio C, Crouch E, Vergano S, et al. Partial uniparental isodisomy of chromosome 16 unmasks a deleterious biallelic mutation in IFT140 that causes Mainzer-Saldino syndrome. Hum Genomics. 2017;11:16 pubmed publisher
    ..studies in cells from the proband showed that the locus produced two transcripts: a majority message containing a mis-splicing event that caused a premature termination codon and a minority message homozygous for the p...
  68. Gordon J, Milshteyn E, Marco Rius I, Ohliger M, Vigneron D, Larson P. Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects. Magn Reson Med. 2017;78:1087-1092 pubmed publisher
    ..The purpose of this work was to explore the impact of slice profile effects on apparent diffusion coefficient (ADC) mapping of hyperpolarized (HP) substrates...
  69. Peigné M, Decanter C. Serum AMH level as a marker of acute and long-term effects of chemotherapy on the ovarian follicular content: a systematic review. Reprod Biol Endocrinol. 2014;12:26 pubmed publisher
    Anti-Müllerian hormone (AMH) is a very sensitive indicator of the ovarian follicular content. Chemotherapeutic agents are notoriously ovariotoxic in that they damage follicles...
  70. Bennett A, Yukich J, Miller J, Keating J, Moonga H, Hamainza B, et al. The relative contribution of climate variability and vector control coverage to changes in malaria parasite prevalence in Zambia 2006-2012. Parasit Vectors. 2016;9:431 pubmed publisher
    Four malaria indicator surveys (MIS) were conducted in Zambia between 2006 and 2012 to evaluate malaria control scale-up...
  71. Kavoussi S, Odenwald K, Boehnlein L, Summers Colquitt R, Pool T, Swain J, et al. Antimüllerian hormone as a predictor of good-quality supernumerary blastocyst cryopreservation among women with levels <1 ng/mL versus 1-4 ng/mL. Fertil Steril. 2015;104:633-6 pubmed publisher
    To determine whether antimüllerian hormone (AMH) levels predict the availability of good-quality supernumerary blastocysts for cryopreservation. Retrospective study. Two fertility centers...
  72. Hirst C, Serralbo O, Ayers K, Roeszler K, Smith C. Genetic Manipulation of the Avian Urogenital System Using In Ovo Electroporation. Methods Mol Biol. 2017;1650:177-190 pubmed publisher
    ..Either vector can both be used for mis-expressing a gene and for targeting endogenous gene knockdown via expression of short hairpin RNAs (shRNAs)...
  73. Yahara M, Kitamura A, Kinjo M. U6 snRNA expression prevents toxicity in TDP-43-knockdown cells. PLoS ONE. 2017;12:e0187813 pubmed publisher
    ..expression of U6 snRNA counteracted the effect of TDP-43 knockdown on cell death, and slightly decreased the mis-splicing rate of Dnajc5 and Sortilin 1 transcripts, which are assisted by TDP-43...
  74. Tauc H, Tasdogan A, Meyer P, Pandur P. Nipped-A regulates intestinal stem cell proliferation in Drosophila. Development. 2017;144:612-623 pubmed publisher
    ..In Drosophila, intestinal stem cell (ISC) proliferation is tightly regulated and mis-regulation is detrimental to intestinal homeostasis...
  75. Tipikin D, Swarts S, Sidabras J, Trompier F, Swartz H. POSSIBLE NATURE OF THE RADIATION-INDUCED SIGNAL IN NAILS: HIGH-FIELD EPR, CONFIRMING CHEMICAL SYNTHESIS, AND QUANTUM CHEMICAL CALCULATIONS. Radiat Prot Dosimetry. 2016;172:112-120 pubmed publisher
    ..the treatment used to recover the RIS2 also has the ability to recover an interfering, mechanically-induced signal (MIS) formed when the nail is clipped...
  76. Signorile P, Petraglia F, Baldi A. Anti-mullerian hormone is expressed by endometriosis tissues and induces cell cycle arrest and apoptosis in endometriosis cells. J Exp Clin Cancer Res. 2014;33:46 pubmed publisher
    The anti-mullerian hormone (AMH) is a member of the transforming growth factor ? (TGF-?) superfamily, which is responsible of the regression of the mullerian duct...