AGPS

Summary

Gene Symbol: AGPS
Description: alkylglycerone phosphate synthase
Alias: ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY, RCDP3, alkyldihydroxyacetonephosphate synthase, peroxisomal, aging-associated gene 5 protein, aging-associated protein 5, alkyl-DHAP synthase
Species: human
Products:     AGPS

Top Publications

  1. Hande A, Katageri I, Jadhav M, Adiger S, Gamanagatti S, Padmalatha K, et al. Transcript profiling of genes expressed during fibre development in diploid cotton (Gossypium arboreum L.). BMC Genomics. 2017;18:675 pubmed publisher
    ..of VLCFA chain, transcripts necessary for energy and cell wall metabolism, EXPANSINs, arabinogalactan proteins (AGPs), tubulin might also be the probable reason for reduced growth of fibres in the Fl...
  2. Buchert R, Tawamie H, Smith C, Uebe S, Innes A, Al Hallak B, et al. A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. Am J Hum Genet. 2014;95:602-10 pubmed publisher
    ..Mutations in PEX7, GNPAT, and AGPS, all involved in the plasmalogen-biosynthesis pathway, have been described in individuals with RCDP...
  3. Cummings J, Atri A, Ballard C, Boneva N, Frolich L, Molinuevo J, et al. Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer's disease clinical program. Alzheimers Res Ther. 2018;10:116 pubmed publisher
    ..0) and USA/Canada (17.5) than in other regions (16.9-17.1). Baseline AD Assessment Scale-Cognitive subscale (ADAS-Cog) scores ranged from 24.3 in USA/Canada to 27.2 in South America/Mexico...
  4. Mohamed W, Salama R, Schaalan M. A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway. Biomed Pharmacother. 2019;111:714-723 pubmed publisher
    ..by the Mini-Mental State Examination (MMSE) and Alzheimer's Disease Assessment Scale-Cognitive Subscale 11-item (ADAS-COG 11) questionnaires as clinical endpoints...
  5. Buckalew V. Role of endogenous digitalis-like factors in the clinical manifestations of severe preeclampsia: a sytematic review. Clin Sci (Lond). 2018;132:1215-1242 pubmed publisher
    ..was discovered in fetal and neonatal blood accidentally because it cross-reacts with antidigoxin antibodies (ADAs)...
  6. Johnson K, Cassin A, Lonsdale A, Wong G, Soltis D, Miles N, et al. Insights into the Evolution of Hydroxyproline-Rich Glycoproteins from 1000 Plant Transcriptomes. Plant Physiol. 2017;174:904-921 pubmed publisher
    ..the HRGP superfamily, which is commonly divided into three major multigene families: the arabinogalactan proteins (AGPs), extensins (EXTs), and proline-rich proteins...
  7. Sato K, Tsuji A, Usumoto Y, Kudo K, Yokoyama T, Ikeda N. Expression of mRNA in the frontal cortex and hypothalamus in a rat model of acute carbon dioxide poisoning. Leg Med (Tokyo). 2016;19:101-6 pubmed publisher
    ..of microarrays data, we selected the following genes for further analysis: alkylglycerone phosphate synthase (Agps), hypocretin (Hcrt), tyrosine hydroxylase (Th), heat shock protein beta 2 (Hspb2), and opioid receptor delta 1 (..
  8. Novak P, Schmidt R, Kontsekova E, Kovacech B, Smolek T, Katina S, et al. FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer's disease. Alzheimers Res Ther. 2018;10:108 pubmed publisher
    ..of booster doses; cognitive assessment via 11-item Alzheimer's Disease Assessment Scale cognitive assessment (ADAS-Cog), Category Fluency Test and Controlled Oral Word Association Test; assessment of brain atrophy via magnetic ..
  9. Luo S, Hu W, Wang Y, Liu B, Yan H, Xiang Y. Genome-wide identification, classification, and expression of phytocyanins in Populus trichocarpa. Planta. 2018;247:1133-1148 pubmed publisher
    ..The majority of PCs are chimeric arabinogalactan proteins (AGPs). In this work, we identified 74 PC genes in Populus trichocarpa and analyzed them comprehensively...

More Information

Publications145 found, 100 shown here

  1. Salaheen S, Kim S, Haley B, Van Kessel J, Biswas D. Alternative Growth Promoters Modulate Broiler Gut Microbiome and Enhance Body Weight Gain. Front Microbiol. 2017;8:2088 pubmed publisher
    Antibiotic growth promoters (AGPs) are frequently used to enhance weight-gain in poultry production...
  2. Karle A, Spindeldreher S, Kolbinger F. Secukinumab, a novel anti-IL-17A antibody, shows low immunogenicity potential in human in vitro assays comparable to other marketed biotherapeutics with low clinical immunogenicity. MAbs. 2016;8:536-50 pubmed publisher
    ..monoclonal antibodies (mAbs)--can be immunogenic, leading to formation of anti-drug antibodies (ADAs) that can result in unwanted effects, including hypersensitivity reactions or compromised therapeutic efficacy...
  3. Duker A, Niiler T, Eldridge G, Brereton N, Braverman N, Bober M. Growth charts for individuals with rhizomelic chondrodysplasia punctata. Am J Med Genet A. 2017;173:108-113 pubmed publisher
    ..inheritance, and their associated genes are known: RCDP type 1 with PEX7, RCDP type 2 with GNPAT, RCDP type 3 with AGPS, RCDP type 4 with FAR1, and RCDP type 5 with PEX5...
  4. Yan L, Wang B, Chia Y, Roskos L. Population Pharmacokinetic Modeling of Benralizumab in Adult and Adolescent Patients with Asthma. Clin Pharmacokinet. 2019;: pubmed publisher
    ..Only body weight and antidrug antibodies (ADAs) were identified as relevant PK covariates...
  5. Birks J, Grimley Evans J. Rivastigmine for Alzheimer's disease. Cochrane Database Syst Rev. 2015;:CD001191 pubmed publisher
    ..with better outcomes for cognitive function measured with the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) score (mean difference (MD) -1.79; 95% confidence interval (CI) -2.21 to -1...
  6. Foroutan N, Hopkins R, Tarride J, Florez I, Levine M. Safety and efficacy of active and passive immunotherapy in mild-to-moderate Alzheimer's disease: A systematic review and network meta-analysis. Clin Invest Med. 2019;42:E53-E65 pubmed publisher
    ..Important AD cognitive scales as clinical efficacy outcomes were ADAS-cog, CDR and MMSE whereas edema, neoplasms and mortality were included as safety outcomes...
  7. Ascher Svanum H, Chen Y, Hake A, Kahle Wrobleski K, Schuster D, Kendall D, et al. Cognitive and Functional Decline in Patients With Mild Alzheimer Dementia With or Without Comorbid Diabetes. Clin Ther. 2015;37:1195-205 pubmed publisher
    ..Cognition was assessed using the 14-item AD Assessment Scale-Cognitive Subscale (ADAS-Cog14) and the MMSE...
  8. Montero Odasso M, Almeida Q, Burhan A, Camicioli R, Doyon J, Fraser S, et al. SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. BMC Geriatr. 2018;18:93 pubmed publisher
    ..The primary outcome measure is the ADAS-Cog (13 and plus modalities) measured at baseline and at 6 months of follow-up...
  9. McMaster M, Kim S, Clare L, Torres S, D Este C, Anstey K. Body, Brain, Life for Cognitive Decline (BBL-CD): protocol for a multidomain dementia risk reduction randomized controlled trial for subjective cognitive decline and mild cognitive impairment. Clin Interv Aging. 2018;13:2397-2406 pubmed publisher
    ..Primary outcome measures are cognition (The Alzheimer's Disease Assessment Scale-Cognitive-Plus [ADAS-Cog-Plus]) and a composite lifestyle risk factor score for Alzheimer's disease (Australian National University - ..
  10. Gao Y, Fangel J, Willats W, Vivier M, Moore J. Dissecting the polysaccharide-rich grape cell wall changes during winemaking using combined high-throughput and fractionation methods. Carbohydr Polym. 2015;133:567-77 pubmed publisher
    ..showed a fraction rich in rhamnogalacturonan I (RGI), homogalacturonan (HG) and arabinogalactan proteins (AGPs)...
  11. Yozu M, Kumarasinghe M, Brown I, Gill A, Rosty C. Australasian Gastrointestinal Pathology Society (AGPS) consensus guidelines for universal defective mismatch repair testing in colorectal carcinoma. Pathology. 2019;51:233-239 pubmed publisher
    ..On behalf of the Australasian Gastrointestinal Pathology Society (AGPS), we present in this manuscript consensus guidelines for Lynch syndrome screening in patients with colorectal ..
  12. Betekhtin A, Milewska Hendel A, Chajec L, Rojek M, Nowak K, Kwaśniewska J, et al. 5-Azacitidine Induces Cell Death in a Tissue Culture of Brachypodium distachyon. Int J Mol Sci. 2018;19: pubmed publisher
    ..Our studies also included an analysis of the distribution of some arabinogalactan proteins (AGPs) and extensin epitopes, which can be used as markers of cells that are undergoing death in a Brachypodium ..
  13. Abushakra S, Porsteinsson A, Vellas B, Cummings J, Gauthier S, Hey J, et al. Clinical Benefits of Tramiprosate in Alzheimer's Disease Are Associated with Higher Number of APOE4 Alleles: The "APOE4 Gene-Dose Effect". J Prev Alzheimers Dis. 2016;3:219-228 pubmed publisher
    ..Co-primary outcomes in both studies were change from baseline in the ADAS-cog11 and CDR-SB assessment scales...
  14. Liu H, Lu X, Chen J. Full-length and a smaller globular fragment of adiponectin have opposite roles in regulating monocyte/macrophage functions in ayu, Plecoglossus altivelis. Fish Shellfish Immunol. 2018;82:319-329 pubmed publisher
    ..Multiple sequence alignment revealed that PaADP presented typical characteristics of ADPs. Phylogenetic tree analysis showed that PaADP was most closely related to that of rainbow trout...
  15. Fang K, Gao S, Zhang W, Xing Y, Cao Q, Qin L. Addition of Phenylboronic Acid to Malus domestica Pollen Tubes Alters Calcium Dynamics, Disrupts Actin Filaments and Affects Cell Wall Architecture. PLoS ONE. 2016;11:e0149232 pubmed publisher
    ..that PBA caused an increase in the abundance of callose, de-esterified pectins and arabinogalactan proteins (AGPs) at the tip. However, it had no effect on the deposition of the wall polymers cellulose...
  16. Askelson T, Flores C, Dunn Horrocks S, Dersjant Li Y, Gibbs K, Awati A, et al. Effects of direct-fed microorganisms and enzyme blend co-administration on intestinal bacteria in broilers fed diets with or without antibiotics. Poult Sci. 2018;97:54-63 pubmed publisher
    ..of broiler chickens which were administered the feed additive was comparable to those fed a diet containing AGPs. Characterization of the gastrointestinal microbiota using culture-dependent methods determined administration of ..
  17. Nozu K, Nakanishi K, Abe Y, Udagawa T, Okada S, Okamoto T, et al. A review of clinical characteristics and genetic backgrounds in Alport syndrome. Clin Exp Nephrol. 2019;23:158-168 pubmed publisher
    ..of inheritance, namely, X-linked Alport syndrome (XLAS), autosomal recessive AS (ARAS), and autosomal dominant AS (ADAS). XLAS is caused by pathogenic variants in COL4A5, while ADAS and ARAS are caused by those in COL4A3/COL4A4...
  18. Wang Y, Hou Y, Qiu J, Li Z, Zhao J, Tong X, et al. A Quantitative Acetylomic Analysis of Early Seed Development in Rice (Oryza sativa L.). Int J Mol Sci. 2017;18: pubmed publisher
    ..acetylated proteins among the three stages, including adenosine diphosphate (ADP) -glucose pyrophosphorylases (AGPs), PDIL1-1 (protein disulfide isomerase like 1-1), hexokinases, pyruvate dehydrogenase complex (PDC) and numerous ..
  19. Rendošová M, Vargová Z, Sabolova D, Imrichová N, Hudecová D, Gyepes R, et al. Silver pyridine-2-sulfonate complex - its characterization, DNA binding, topoisomerase I inhibition, antimicrobial and anticancer response. J Inorg Biochem. 2018;186:206-216 pubmed publisher
    ..Polymeric form of {[Ag(py-2-SO3)]}n (AgPS) was synthesized and characterized by analytical techniques (IR, CHN, TG/DTA, MS) and its molecular formula was ..
  20. Pardridge W, Boado R, Giugliani R, Schmidt M. Plasma Pharmacokinetics of Valanafusp Alpha, a Human Insulin Receptor Antibody-Iduronidase Fusion Protein, in Patients with Mucopolysaccharidosis Type I. BioDrugs. 2018;32:169-176 pubmed publisher
    ..tested subjects had been receiving laronidase ERT for years, and some showed high levels of anti-drug antibodies (ADAs)...
  21. Staton T, Peng K, Owen R, Choy D, Cabanski C, Fong A, et al. A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers. BMC Pulm Med. 2019;19:5 pubmed publisher
    ..A and B, 16 of 30 (53%) and 16 of 17 (94%) active subjects, respectively, tested positive for anti-drug antibodies (ADAs). No anaphylaxis or hypersensitivity events occurred...
  22. Youssef M, Ibrahim A, Akashi K, Hossain M. PUFA-Plasmalogens Attenuate the LPS-Induced Nitric Oxide Production by Inhibiting the NF-kB, p38 MAPK and JNK Pathways in Microglial Cells. Neuroscience. 2019;397:18-30 pubmed publisher
    ..of Pls synthesizing enzymes, glycerone phosphate O-acyltransferase (GNPAT) and alkylglycerone phosphate synthase (AGPS) in the microglial cells by the p38MAPK and JNK pathways...
  23. Gates N, Valenzuela M, Sachdev P, Singh N, Baune B, Brodaty H, et al. Study of Mental Activity and Regular Training (SMART) in at risk individuals: a randomised double blind, sham controlled, longitudinal trial. BMC Geriatr. 2011;11:19 pubmed publisher
    ..Primary outcomes measured at baseline, 6, and 18 months are the Alzheimer's Disease Assessment Scale (ADAS-Cog), neuropsychological test scores, and Bayer Informant Instrumental Activities of Daily Living (B-IADLs)...
  24. Yoshimi Y, Sugawara Y, Hori C, Igarashi K, Kaneko S, Tsumuraya Y, et al. A protease/peptidase from culture medium of Flammulina velutipes that acts on arabinogalactan-protein. Biosci Biotechnol Biochem. 2017;81:475-481 pubmed publisher
    Arabinogalactan-proteins (AGPs) are highly diverse plant proteoglycans found on the plant cell surface. AGPs have large arabinogalactan (AG) moieties attached to a core-protein rich in hydroxyproline (Hyp)...
  25. Pielach A, Leroux O, Domozych D, Knox J, Popper Z. Arabinogalactan protein-rich cell walls, paramural deposits and ergastic globules define the hyaline bodies of rhinanthoid Orobanchaceae haustoria. Ann Bot. 2014;114:1359-73 pubmed publisher
    ..bodies, intercellular deposits and globular ergastic bodies composed of pectins, xyloglucans, extensins and AGPs were common. In Rhinanthus they were particularly abundant in pairings with legume hosts...
  26. Perera M, Aggarwal L, Scott I, Logan B. Received care compared to ADP-guided care of patients admitted to hospital with chest pain of possible cardiac origin. Int J Gen Med. 2018;11:345-351 pubmed publisher
    To assess the extent to which accelerated diagnostic protocols (ADPs), compared to traditional care, identify patients presenting to emergency departments (EDs) with chest pain who are at low cardiac risk and eligible for early ED ..
  27. Dowling N, Johnson S, Gleason C, Jagust W. The mediational effects of FDG hypometabolism on the association between cerebrospinal fluid biomarkers and neurocognitive function. Neuroimage. 2015;105:357-68 pubmed publisher
    ..and changes in cognition, measured with the 13-item Alzheimer Disease's Assessment Scale-cognitive subscale (ADAS-Cog)...
  28. King E, Mazor R, Cuburu N, Pastan I. Low-Dose Methotrexate Prevents Primary and Secondary Humoral Immune Responses and Induces Immune Tolerance to a Recombinant Immunotoxin. J Immunol. 2018;200:2038-2045 pubmed publisher
    ..We found that low-dose MTX combined with LMB-100 completely suppressed the formation of ADAs in a dose- and frequency-dependent manner...
  29. De Beaumont L, Pelleïeux S, Lamarre Théroux L, Dea D, Poirier J. Butyrylcholinesterase K and Apolipoprotein E-?4 Reduce the Age of Onset of Alzheimer's Disease, Accelerate Cognitive Decline, and Modulate Donepezil Response in Mild Cognitively Impaired Subjects. J Alzheimers Dis. 2016;54:913-922 pubmed
    ..of BCHE and APOE variants on donepezil drug response using the Alzheimer's Disease Assessment Score-Cognition (ADAS-Cog) scale...
  30. Lamb Y, Deeks E. Sarilumab: A Review in Moderate to Severe Rheumatoid Arthritis. Drugs. 2018;78:929-940 pubmed publisher
    ..In the minority of patients who tested positive for anti-drug antibodies (ADAs), ADAs did not impact efficacy or increase adverse reactions...
  31. Abushouk A, Elmaraezy A, Aglan A, Salama R, Fouda S, Fouda R, et al. Bapineuzumab for mild to moderate Alzheimer's disease: a meta-analysis of randomized controlled trials. BMC Neurol. 2017;17:66 pubmed publisher
    ..was not superior to the placebo group in terms of change from baseline in Alzheimer's disease assessment scale (ADAS)-Cog11 (MD = 0.14, 95% CI [-0.72, 0.99]), disability assessment for dementia (DAD) scale (MD = 1.35, 95% CI [-1...
  32. Jia Q, Zhu J, Xu X, Lou Y, Zhang Z, Zhang Z, et al. Arabidopsis AT-hook protein TEK positively regulates the expression of arabinogalactan proteins in controlling nexine layer formation in the pollen wall. Mol Plant. 2014;: pubmed
    ..the molecular function of TEK in pollen development and identified direct targets of TEK, Arabinogalactan proteins (AGPs), which are responsible for nexine formation...
  33. Pietzner K, Vergote I, Santoro A, Chekerov R, Marmé F, Rosenberg P, et al. Re-challenge with catumaxomab in patients with malignant ascites: results from the SECIMAS study. Med Oncol. 2014;31:308 pubmed publisher
    ..events (pyrexia, nausea, vomiting and abdominal pain), safety, efficacy and the occurrence of anti-drug antibodies (ADAs). Eight of nine screened patients received a second catumaxomab cycle...
  34. Betekhtin A, Rojek M, Milewska Hendel A, Gawecki R, Karcz J, Kurczynska E, et al. Spatial Distribution of Selected Chemical Cell Wall Components in the Embryogenic Callus of Brachypodium distachyon. PLoS ONE. 2016;11:e0167426 pubmed publisher
    ..Furthermore, we demonstrated that AGPs and pectins are the components of the extracellular matrix network in Brachypodium embryogenic culture...
  35. Li Y, Li Y, Zhao M, Yuan A, Gong X, Zhao M, et al. The Effects of Rheum palmatum L. on the Pharmacokinetic of Major Diterpene Alkaloids of Aconitum carmichaelii Debx. in Rats. Eur J Drug Metab Pharmacokinet. 2017;42:441-451 pubmed publisher
    ..C max, AUClast of monoester diterpene alkaloids (MDAs) and amine diterpenoid alkaloids (ADAs) were 152.42, 1238.95, 287.96, 123...
  36. Mo G, Baldwin J, Luffer Atlas D, Ilaria R, Conti I, Heathman M, et al. Population Pharmacokinetic Modeling of Olaratumab, an Anti-PDGFRα Human Monoclonal Antibody, in Patients with Advanced and/or Metastatic Cancer. Clin Pharmacokinet. 2018;57:355-365 pubmed publisher
    ..A small subset of patients developed treatment-emergent anti-drug antibodies (TE-ADAs); however, TE-ADAs did not have any effect on CL or PK time course of olaratumab...
  37. Klepsch M, Schmitt M, Paul Knox J, Jansen S. The chemical identity of intervessel pit membranes in Acer challenges hydrogel control of xylem hydraulic conductivity. AoB Plants. 2016;8: pubmed publisher
    ..to the presence of pectins and/or other cell-wall matrix polymers such as heteroxylans or arabinogalactan-proteins (AGPs) that may contain acidic sugars...
  38. Götze H, Friedrich M, Brähler E, Romer G, Mehnert A, Ernst J. Psychological distress of cancer patients with children under 18 years and their partners-a longitudinal study of family relationships using dyadic data analysis. Support Care Cancer. 2017;25:255-264 pubmed
    ..Depression Scale (HADS), the Oslo 3-item Social Support Scale (OSS-3), and the Abbreviated Dyadic Adjustment Scale (ADAS). We surveyed 161 cancer patients and 115 partners by mail (t1)...
  39. Corral Martínez P, García Fortea E, Bernard S, Driouich A, Segui Simarro J. Ultrastructural Immunolocalization of Arabinogalactan Protein, Pectin and Hemicellulose Epitopes Through Anther Development in Brassica napus. Plant Cell Physiol. 2016;57:2161-2174 pubmed
    ..We used the following monoclonal antibodies: JIM13, JIM8, JIM14 and JIM16 for AGPs, LM5, LM6, JIM7, JIM5 and LM7 for pectins, CCRC-M1, CCRC-M89 and LM15 for xyloglucan, and LM11 for xylan...
  40. Losada J, Hormaza J, Lora J. Pollen-pistil interaction in pawpaw (Asimina triloba), the northernmost species of the mainly tropical family Annonaceae. Am J Bot. 2017;104:1891-1903 pubmed publisher
    ..Stigmatic receptivity is concomitant with the secretion of cell-wall-related arabinogalactan proteins (AGPs)...
  41. Abraham S, Lara Pérez L, Rodríguez C, Contreras Navarro Y, Nuñez Beverido N, Ovruski S, et al. The male ejaculate as inhibitor of female remating in two tephritid flies. J Insect Physiol. 2016;88:40-7 pubmed publisher
    ..Among these is the transfer of the ejaculate composed mainly by sperm and accessory gland proteins (AGPs)...
  42. Atri A, Frolich L, Ballard C, Tariot P, Molinuevo J, Boneva N, et al. Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials. JAMA. 2018;319:130-142 pubmed publisher
    ..from baseline to 24 weeks measured by the 11-item cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-Cog); key secondary end points: Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change Scale ..
  43. Huang Y, Wang Y, Tan L, Sun L, Petrosino J, Cui M, et al. Nanospherical arabinogalactan proteins are a key component of the high-strength adhesive secreted by English ivy. Proc Natl Acad Sci U S A. 2016;113:E3193-202 pubmed publisher
    ..Here we show that these nanoparticles are predominantly composed of arabinogalactan proteins (AGPs), a superfamily of hydroxyproline-rich glycoproteins present in the extracellular spaces of plant cells...
  44. Rabey J, Dobronevsky E. Repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training is a safe and effective modality for the treatment of Alzheimer's disease: clinical experience. J Neural Transm (Vienna). 2016;123:1449-1455 pubmed
    ..Five patients returned for a second treatment. ADAS-Cog and MMSE scores were measured pre- and post-treatments...
  45. Yeo S, Lee S, Park H, Shin H, Holzapfel W, Huh C. Development of putative probiotics as feed additives: validation in a porcine-specific gastrointestinal tract model. Appl Microbiol Biotechnol. 2016;100:10043-10054 pubmed
    Enforced restrictions on the use of antibiotics as growth promoters (AGPs) in animal production have prompted investigations into alternative feed additives in recent decades...
  46. Costa M, Bessegatto J, Alfieri A, Weese J, Filho J, Oba A. Different antibiotic growth promoters induce specific changes in the cecal microbiota membership of broiler chicken. PLoS ONE. 2017;12:e0171642 pubmed publisher
    ..study used high throughput sequencing to characterize the impact of several antimicrobials in broiler chicken under controlled conditions and add new insights to the current knowledge on how AGPs affect the cecal microbiota of chicken.
  47. Huang D, Zhao X, Liu X, Chao R. Determination of Five Aminoalcohol-diterpenoid Alkaloids in the Lateral Root of Aconitum carmichaeli by HPLC-ELSD with SPE. J Chromatogr Sci. 2017;55:940-945 pubmed publisher
    ..using solid phase extraction (SPE) was established for quantification of five aminoalcohol-diterpenoid alkaloids (ADAs), including mesaconine, aconine, hypaconine, fuziline and neoline, in the lateral roots of Aconitum carmichaeli (..
  48. Vande Casteele N. Assays for measurement of TNF antagonists in practice. Frontline Gastroenterol. 2017;8:236-242 pubmed publisher
    ..One of the main factors leading to suboptimal drug exposure is the formation of antidrug antibodies (ADAs), due to an immunogenic reaction of the immune system towards the non-self protein...
  49. Chen Y, Zhang J, Wang Y, Yuan J, Hu W. Efficacy of Cholinesterase Inhibitors in Vascular Dementia: An Updated Meta-Analysis. Eur Neurol. 2016;75:132-41 pubmed publisher
    ..Donepezil showed significant improvement in Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) as compared to placebo, at the doses tested, that is, 5 and 10 mg/day (difference in means -1.389 and -1...
  50. Smits L, Derikx L, de Jong D, Boshuizen R, van Esch A, Drenth J, et al. Clinical Outcomes Following a Switch from Remicade® to the Biosimilar CT-P13 in Inflammatory Bowel Disease Patients: A Prospective Observational Cohort Study. J Crohns Colitis. 2016;10:1287-1293 pubmed
    ..C-reactive protein [CRP], faecal calprotectin [FCP], infliximab trough level [TL] and anti-drug antibodies [ADAs] and documented adverse events...
  51. Gault L, Lenz R, Ritchie C, Meier A, Othman A, Tang Q, et al. ABT-126 monotherapy in mild-to-moderate Alzheimer's dementia: randomized double-blind, placebo and active controlled adaptive trial and open-label extension. Alzheimers Res Ther. 2016;8:44 pubmed
    ..was the change from baseline to week 24 in the 11-item Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) total score. Subjects completing the double-blind study could enroll in the 28-week open-label extension study...
  52. Doraiswamy P, Sperling R, Coleman R, Johnson K, Reiman E, Davis M, et al. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology. 2012;79:1636-44 pubmed publisher
    ..were associated with greater clinical worsening on the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog (p < 0.01) and Clinical Dementia Rating-sum of boxes (CDR-SB) (p < 0.02)...
  53. Wang G, Demirakca T, van Eijk J, Frischknecht U, Ruf M, Ucar S, et al. Longitudinal Mapping of Gyral and Sulcal Patterns of Cortical Thickness and Brain Volume Regain during Early Alcohol Abstinence. Eur Addict Res. 2016;22:80-9 pubmed publisher
    ..SA), as well as subcortical volume recovery in the first 2 weeks of abstinence in 49 alcohol-dependent patients (ADPs)...
  54. Kobayashi H, Ohnishi T, Nakagawa R, Yoshizawa K. The comparative efficacy and safety of cholinesterase inhibitors in patients with mild-to-moderate Alzheimer's disease: a Bayesian network meta-analysis. Int J Geriatr Psychiatry. 2016;31:892-904 pubmed publisher
    ..We examined Alzheimer's Disease Assessment Scale, cognitive subscale (ADAS-Cog), Neuropsychiatric Inventory (NPI), Clinician's Interview-Based Impression of Change plus caregiver's input (..
  55. Jiao H, Liu X, Sun S, Wang P, Qiao X, Li J, et al. The unique evolutionary pattern of the Hydroxyproline-rich glycoproteins superfamily in Chinese white pear (Pyrus bretschneideri). BMC Plant Biol. 2018;18:36 pubmed publisher
    The hydroxyproline-rich glycoprotein (HRGP) superfamily, comprising three families (arabinogalactan-proteins, AGPs; extensins, EXTs; proline-rich proteins, PRPs), is a class of proline-rich proteins that exhibit high diversity and are ..
  56. Tan X, Yang L, Zhang Y, Zhao F, Chu H, Guo J. Chlorella pyrenoidosa cultivation in outdoors using the diluted anaerobically digested activated sludge. Bioresour Technol. 2015;198:340-50 pubmed publisher
    ..pyrenoidosa) was cultured in outdoors using the diluted anaerobically digested activated sludge (ADAS). The outdoors batch culture in every season showed that C...
  57. Gui L, Tang X, Moura J. Geodesic distance on a Grassmannian for monitoring the progression of Alzheimer's disease. Neuroimage. 2017;146:1016-1024 pubmed publisher
    ..significant correlations between the geodesic distance and the cognitive deterioration as quantified by the ADAS-cog increase and the MMSE decrease...
  58. Suzuki T, Narciso J, Zeng W, van de Meene A, Yasutomi M, Takemura S, et al. KNS4/UPEX1: A Type II Arabinogalactan ?-(1,3)-Galactosyltransferase Required for Pollen Exine Development. Plant Physiol. 2017;173:183-205 pubmed publisher
    ..and staining with the arabinogalactan-protein (AGP)-specific ?-Glc Yariv reagent, we show that the levels of AGPs in the kns4 microspore primexine are considerably diminished, and their location differs from that of wild type, as ..
  59. Yu X, Liu Y, Wu X, Liu L, Fu W, Song D. Isolation, purification, characterization and immunostimulatory activity of polysaccharides derived from American ginseng. Carbohydr Polym. 2017;156:9-18 pubmed publisher
    In this study, crude American ginseng polysaccharide (AGPS) was extracted with hot water and preliminarily purified by using resin S-8 and Polyamide columns...
  60. Lamberth K, Reedtz Runge S, Simon J, Klementyeva K, Pandey G, Padkjær S, et al. Post hoc assessment of the immunogenicity of bioengineered factor VIIa demonstrates the use of preclinical tools. Sci Transl Med. 2017;9: pubmed publisher
    ..in the licensure of a therapeutic protein because the development of neutralizing anti-drug antibodies (ADAs) can affect both safety and efficacy...
  61. Sala K, Malarz K, Barlow P, Kurczynska E. Distribution of some pectic and arabinogalactan protein epitopes during Solanum lycopersicum (L.) adventitious root development. BMC Plant Biol. 2017;17:25 pubmed publisher
    ..However, little is known about the distribution of pectins and AGPs during AR ontogeny, either in the primordium or stem tissues from which AR arise or their correspondence with these ..
  62. Mavros Y, Gates N, Wilson G, Jain N, Meiklejohn J, Brodaty H, et al. Mediation of Cognitive Function Improvements by Strength Gains After Resistance Training in Older Adults with Mild Cognitive Impairment: Outcomes of the Study of Mental and Resistance Training. J Am Geriatr Soc. 2017;65:550-559 pubmed publisher
    ..Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog); global, executive, and memory domains; peak strength (1 repetition maximum); and VO2peak ...
  63. Dao E, Best J, Hsiung G, Sossi V, Jacova C, Tam R, et al. Associations between cerebral amyloid and changes in cognitive function and falls risk in subcortical ischemic vascular cognitive impairment. BMC Geriatr. 2017;17:133 pubmed publisher
    ..Global cognition, executive functions, and information processing speed were measured using: 1) ADAS-Cog; 2) Trail Making Test; 3) Digit Span Test; 4) Stroop Test, and 5) Digit Symbol Substitution Test...
  64. Failamani F, Grytsiv A, Giester G, Polt G, Heinrich P, Michor H, et al. Ba5{V,Nb}12Sb19+x, novel variants of the Ba5Ti12Sb19+x-type: crystal structure and physical properties. Phys Chem Chem Phys. 2015;17:24248-61 pubmed publisher
    ..41 shows additional atom disorder. Temperature dependent ADPs and specific heat of Ba5V12Sb19...
  65. Rahman Z, Zidan A, Korang Yeboah M, Yang Y, Siddiqui A, Shakleya D, et al. Effects of excipients and curing process on the abuse deterrent properties of directly compressed tablets. Int J Pharm. 2017;517:303-311 pubmed publisher
    ..The ADPs studied were tablet crush resistance or hardness, particle size distribution following mechanical manipulation, ..
  66. Tamang M, Sunwoo H, Jeon B. Phage-mediated dissemination of virulence factors in pathogenic bacteria facilitated by antibiotic growth promoters in animals: a perspective. Anim Health Res Rev. 2017;:1-7 pubmed publisher
    ..of antibiotic-resistant pathogens is a looming concern associated with the use of antibiotic growth promoters (AGPs) around the world...
  67. Gaspar J, Schwarz C, Brown T, Kang J. Gaze position modulates the effectiveness of forward collision warnings for drowsy drivers. Accid Anal Prev. 2019;126:25-30 pubmed publisher
    Advanced driver assistance systems (ADAS) have the potential to prevent crashes and reduce their severity...
  68. Dell osso L, Corsi M, Gesi C, Bertelloni C, Massimetti G, Peroni D, et al. Adult Autism Subthreshold Spectrum (AdAS Spectrum) in parents of pediatric patients with epilepsy: Correlations with post-traumatic stress symptoms. Compr Psychiatry. 2018;83:25-30 pubmed publisher
    ..revealed noteworthy correlations between post-traumatic stress symptoms and adult autism subthreshold spectrum (AdAS Spectrum) only in the subgroup of the fathers...
  69. Vokhidov H, Hong H, Kang J, Hoang T, Park K. Recognition of Damaged Arrow-Road Markings by Visible Light Camera Sensor Based on Convolutional Neural Network. Sensors (Basel). 2016;16: pubmed publisher
    ..They are also important input to the automated advanced driver assistance system (ADAS), installed in many automobiles...
  70. Sánchez Aguilera A, Sánchez Alonso J, Vicente Torres M, Colino A. Role of low-voltage-activated calcium current and extracellular calcium in controlling the firing pattern of developing CA1 pyramidal neurons. Neuroscience. 2017;344:89-101 pubmed publisher
    ..Spike after-depolarizations (ADPs) constitute a major factor underlying burst-spiking behavior...
  71. Lim J, Lee J, Kwon H, Lee Y. The correlation between cerebral arterial pulsatility and cognitive dysfunction in Alzheimer's disease patients. J Neurol Sci. 2017;373:285-288 pubmed publisher
    ..state examination (MMSE), clinical dementia rating sum of boxes (SOB), and Alzheimer's Disease Assessment Scale (ADAS-cog), which was further categorized as praxis, language, and memory subscores...
  72. Risacher S, Anderson W, Charil A, Castelluccio P, Shcherbinin S, Saykin A, et al. Alzheimer disease brain atrophy subtypes are associated with cognition and rate of decline. Neurology. 2017;89:2176-2186 pubmed publisher
    ..decline than participants with LPMRI on the Alzheimer's Disease Assessment Scale, 13-Item Subscale (ADAS-Cog13), Mini-Mental State Examination (MMSE), and Functional Assessment Questionnaire (all p < ..
  73. Zhu X, Suk H, Lee S, Shen D. Canonical feature selection for joint regression and multi-class identification in Alzheimer's disease diagnosis. Brain Imaging Behav. 2016;10:818-28 pubmed publisher
    ..PET) images to jointly predict clinical scores of Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) and Mini-Mental State Examination (MMSE) and also identify multi-class disease status for Alzheimer's disease ..
  74. Matz K, Teuschl Y, Firlinger B, Dachenhausen A, Keindl M, Seyfang L, et al. Multidomain Lifestyle Interventions for the Prevention of Cognitive Decline After Ischemic Stroke: Randomized Trial. Stroke. 2015;46:2874-80 pubmed publisher
    ..Primary outcomes were the cognitive subscale of the Alzheimer Disease Assessment Scale (ADAS-cog) and occurrence of cognitive decline in the composite scores of at least 2 of 5 cognitive domains at 24 months...
  75. Atherton N, Bridle C, Brown D, Collins H, Dosanjh S, Griffiths F, et al. Dementia and Physical Activity (DAPA) - an exercise intervention to improve cognition in people with mild to moderate dementia: study protocol for a randomized controlled trial. Trials. 2016;17:165 pubmed publisher
    ..The primary outcome is measured using ADAS-cog. Secondary outcome measures include behavioural symptoms, functional ability, quality of life and carer burden...
  76. Zhang M, Perrin L, Pardo P. A Randomized Phase 1 Study to Assess the Safety and Pharmacokinetics of the Subcutaneously Injected Anti-LIGHT Antibody, SAR252067. Clin Pharmacol Drug Dev. 2017;6:292-301 pubmed publisher
    ..No serious AEs were reported, and no dose-effect relationship was apparent. Injection-site reactions were minimal. ADAs were not clinically relevant...
  77. Mishra N, Smyth J. Oral vaccination of broiler chickens against necrotic enteritis using a non-virulent NetB positive strain of Clostridium perfringens type A. Vaccine. 2017;35:6858-6865 pubmed publisher
    ..The disease is well controlled by the use of in-feed antibiotic growth promoters (AGPs)...
  78. Biermann J, van den Bosch H. In vitro processing of the human alkyl-dihydroxyacetonephosphate synthase precursor. Arch Biochem Biophys. 1999;368:139-46 pubmed
    ..Processing of alkyl-dihydroxyacetonephosphate synthase did not increase the activity of the enzyme. This indicates that the presence of the presequence does not affect the activity of the enzyme. ..
  79. Biermann J, Gootjes J, Wanders R, van den Bosch H. Stability of alkyl-dihydroxyacetonephosphate synthase in human control and peroxisomal disorder fibroblasts. IUBMB Life. 1999;48:635-9 pubmed
    ..Additionally, they indicate that both the precursor and mature form of alkyl-DHAP synthase exhibit considerable intraperoxisomal turnover. ..
  80. Brown K, Uwiera R, Kalmokoff M, Brooks S, Inglis G. Antimicrobial growth promoter use in livestock: a requirement to understand their modes of action to develop effective alternatives. Int J Antimicrob Agents. 2017;49:12-24 pubmed publisher
    ..AMAs) have been used in agriculture since the 1950s as growth-promoting agents [antimicrobial growth promoters (AGPs)]...
  81. Shirayama Y, Takahashi M, Oda Y, Yoshino K, Sato K, Okubo T, et al. rCBF and cognitive impairment changes assessed by SPECT and ADAS-cog in late-onset Alzheimer's disease after 18 months of treatment with the cholinesterase inhibitors donepezil or galantamine. Brain Imaging Behav. 2019;13:75-86 pubmed publisher
    ..We assessed cognitive function using the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) grouped into three subgroup domains, language, memory, and praxis...
  82. Chen G, Mickolajczyk K, Hancock W. The Kinesin-5 Chemomechanical Cycle Is Dominated by a Two-heads-bound State. J Biol Chem. 2016;291:20283-20294 pubmed publisher
    ..First, upon microtubule binding, dimeric Eg5 releases both bound ADPs. Second, microtubule dissociation in saturating ADP is 20-fold slower for the dimer than for the monomer...
  83. Liu Seifert H, Andersen S, Case M, Sparks J, Holdridge K, Wessels A, et al. Statistical properties of continuous composite scales and implications for drug development. J Biopharm Stat. 2017;27:1104-1114 pubmed publisher
    ..the composite Integrated AD Rating Scale (iADRS) and its components, the AD Assessment Scale-Cognitive subscale (ADAS-Cog) and AD Cooperative Study-Activities of Daily Living inventory, instrumental items (ADCS-iADL) were consistent ..
  84. Tang S, Sieo C, Ramasamy K, Saad W, Wong H, Ho Y. Performance, biochemical and haematological responses, and relative organ weights of laying hens fed diets supplemented with prebiotic, probiotic and synbiotic. BMC Vet Res. 2017;13:248 pubmed publisher
    The increasing trend of ban on the use of antibiotic growth promoters (AGPs) across the globe in the poultry industry has led to a growing need for alternatives to AGPs...
  85. Johansson H, Lundin Olsson L, Littbrand H, Gustafson Y, Rosendahl E, Toots A. Cognitive function and walking velocity in people with dementia; a comparison of backward and forward walking. Gait Posture. 2017;58:481-486 pubmed publisher
    ..Global cognitive outcome measurements included MMSE and Alzheimer Disease Assessment Scale - Cognitive subscale (ADAS-Cog). Executive function was measured using Verbal Fluency (VF)...
  86. Rahman M, Lesch M, Horrey W, Strawderman L. Assessing the utility of TAM, TPB, and UTAUT for advanced driver assistance systems. Accid Anal Prev. 2017;108:361-373 pubmed publisher
    Advanced Driver Assistance Systems (ADAS) are intended to enhance driver performance and improve transportation safety...
  87. Andersen M, Boos I, Ruprecht C, Willats W, Pfrengle F, Clausen M. Synthesis and Application of Branched Type II Arabinogalactans. J Org Chem. 2017;: pubmed publisher
    ..synthesis of linear and (1 ? 6)-branched ?-(1 ? 3)-d-galactans, structures found in plant arabinogalactan proteins (AGPs), is described...
  88. Smart D. Back to the future: occupational diver training in Australia. Diving Hyperb Med. 2017;47:214-215 pubmed publisher
    The Australian Diver Accreditation Scheme (ADAS) had its genesis in the 1990s in response to a need to produce occupational divers who were trained to international standards with the necessary skills to safely undertake complex work in ..
  89. Biermann J, Gootjes J, Humbel B, Dansen T, Wanders R, van den Bosch H. Immunological analyses of alkyl-dihydroxyacetone-phosphate synthase in human peroxisomal disorders. Eur J Cell Biol. 1999;78:339-48 pubmed
    ..Immunoelectron microscopy showed that the enzyme is predominantly located on the lumenal side of the peroxisomal membrane in rat and guinea pig liver. ..
  90. Wanders R, Waterham H. Biochemistry of mammalian peroxisomes revisited. Annu Rev Biochem. 2006;75:295-332 pubmed
  91. Kishnani P, Dickson P, Muldowney L, Lee J, Rosenberg A, Abichandani R, et al. Immune response to enzyme replacement therapies in lysosomal storage diseases and the role of immune tolerance induction. Mol Genet Metab. 2016;117:66-83 pubmed publisher
    ..to Enzyme Replacement Therapies: Role of Immune Tolerance Induction" to discuss the impact of anti-drug antibodies (ADAs) on efficacy and safety of enzyme replacement therapies (ERTs) intended to treat patients with lysosomal storage ..
  92. Zhu X, Suk H, Wang L, Lee S, Shen D. A novel relational regularization feature selection method for joint regression and classification in AD diagnosis. Med Image Anal. 2017;38:205-214 pubmed publisher
    ..With the dimension-reduced data, we train two support vector regression models to predict the clinical scores of ADAS-Cog and MMSE, respectively, and also a support vector classification model to determine the clinical label...