Gene Symbol: ACSF3
Description: acyl-CoA synthetase family member 3
Alias: acyl-CoA synthetase family member 3, mitochondrial, malonyl-CoA synthetase
- Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality controlElizabeth J Klemm
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA
J Biol Chem 286:37602-14. 2011..These findings indicate a possible connection between ER protein quality control and lipid droplets...
- The CBFA2T3/ACSF3 locus is recurrently involved in IGH chromosomal translocation t(14;16)(q32;q24) in pediatric B-cell lymphoma with germinal center phenotypeItziar Salaverria
Institute of Human Genetics, University Hospital Schleswig Holstein Campus Kiel Christian Albrechts University, Kiel, Germany
Genes Chromosomes Cancer 51:338-43. 2012..3). Candidate oncogenes targeted through this translocation are CBFA2T3 and ACSF3, which could be activated on der(16) and der(14), respectively...
- Analysis of differentially expressed genes and microRNAs in alcoholic liver diseaseYing Liu
Department of Gastroenterology, Heilongjiang Province Hospital, Harbin, Heilongjiang 150036, PR China
Int J Mol Med 31:547-54. 2013..co-expression genetic networks, node genes modulating the network were Acyl-coenzyme A synthetase-3 (ACSF3), Frizzled-5 (FZD5), LOC727987 and C1orf222...
- Combined malonic and methylmalonic aciduria: exome sequencing reveals mutations in the ACSF3 gene in patients with a non-classic phenotypeAhmed Alfares
Department of Medical Genetics, Montreal Children s Hospital, McGill University, Montreal, Quebec, Canada
J Med Genet 48:602-5. 2011..Most patients have metabolic acidosis, developmental delay, seizures and cardiomyopathy. CMAMMA was also described in symptomatic patients with normal MCD activity, suggesting heterogeneity in this disorder...
- Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduriaJennifer L Sloan
Genetics and Molecular Biology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA
Nat Genet 43:883-6. 2011..We identify mutations in ACSF3, encoding a putative methylmalonyl-CoA and malonyl-CoA synthetase as a cause of CMAMMA...
- Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesisAndrzej Witkowski
Children s Hospital Oakland Research Institute, Oakland, California 94609, USA
J Biol Chem 286:33729-36. 2011..The human candidate protein ACSF3, which has a predicted N-terminal mitochondrial targeting sequence, was cloned, expressed, and characterized as a ..
- Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genomePaul A Watkins
Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
J Lipid Res 48:2736-50. 2007..Knowing the full complement of ACS genes in the human genome will facilitate future studies to characterize their specific biological functions...
- Brain Uptake and Utilization of Fatty Acids and LipidsPaul Watkins; Fiscal Year: 2004..Mol. Neurosci., which has committed to publish the proceedings of the proposed meeting. ..
- XALD: Role of Very Long Chain Fatty Acyl-CoA SynthetasesPaul Watkins; Fiscal Year: 2006..Furthermore, they will facilitate elucidation of the role of enzymes belonging to the VLACS or BG families in XALD. [unreadable] [unreadable]..