ABR

Summary

Gene Symbol: ABR
Description: ABR, RhoGEF and GTPase activating protein
Alias: MDB, active breakpoint cluster region-related protein, active BCR-related
Species: human
Products:     ABR

Top Publications

  1. Dai C, Lehar M, Sun D, Rvt L, Carey J, MacLachlan T, et al. Rhesus Cochlear and Vestibular Functions Are Preserved After Inner Ear Injection of Saline Volume Sufficient for Gene Therapy Delivery. J Assoc Res Otolaryngol. 2017;18:601-617 pubmed publisher
    ..Compared to its pretreatment values, no treated ear's ABR threshold had worsened by more than 5 dB at any stimulus frequency; distortion product otoacoustic emissions ..
  2. Xu Y, Shan X, Liu Y, Pu Y, Wang C, Tao Q, et al. Olfactory epithelium neural stem cell implantation restores noise-induced hearing loss in rats. Neurosci Lett. 2016;616:19-25 pubmed publisher
    ..Then, oe-NSCs were implanted into cochlear tissue by retroauricular approach. Auditory brainstem response (ABR) method was used to evaluate the hearing function...
  3. Levada K, Guldiken N, Zhang X, Vella G, Mo F, James L, et al. Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling. J Hepatol. 2018;68:996-1005 pubmed publisher
    ..diet (DDC; 12 weeks) was used to induce lipotoxic injury and Mallory-Denk body (MDB) formation, respectively. Primary hepatocytes were treated with palmitic acid...
  4. Tian C, Harris B, Johnson K. Ectopic Mineralization and Conductive Hearing Loss in Enpp1asj Mutant Mice, a New Model for Otitis Media and Tympanosclerosis. PLoS ONE. 2016;11:e0168159 pubmed publisher
    ..Auditory-evoked brainstem response (ABR) measurements revealed that around 90% of the mutant mice (Enpp1asj/asj) tested had moderate to severe hearing ..
  5. Martínez Vega R, Partearroyo T, Vallecillo N, Varela Moreiras G, Pajares M, Varela Nieto I. Long-term omega-3 fatty acid supplementation prevents expression changes in cochlear homocysteine metabolism and ameliorates progressive hearing loss in C57BL/6J mice. J Nutr Biochem. 2015;26:1424-33 pubmed publisher
    ..long-term omega-3 supplementation to evaluate the impact on hearing by analyzing their auditory brainstem response (ABR) and distortion product otoacoustic emissions (DPOAE) thresholds...
  6. Han C, Kim M, Ding D, Park H, White K, Walker L, et al. GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR. PLoS ONE. 2017;12:e0180817 pubmed publisher
    ..However, Gsr deficiency did not affect ABR (auditory brainstem response) hearing thresholds, wave I amplitudes or wave I latencies in young mice...
  7. Dong Y, Guo C, Ding Y, Zhang Y, Song H, Peng Y, et al. Effects of Erlong Zuoci decoction on the age-related hearing loss in C57BL/6J mice. J Ethnopharmacol. 2016;181:59-65 pubmed publisher
    ..Auditory brainstem response (ABR) was used to assess the hearing function of mice...
  8. Halonen J, Hinton A, Frisina R, Ding B, Zhu X, Walton J. Long-term treatment with aldosterone slows the progression of age-related hearing loss. Hear Res. 2016;336:63-71 pubmed publisher
    ..Long-term treatment with aldosterone improved both behavioral and physiological measures of hearing (ABR thresholds)...
  9. Mutai H, Miya F, Fujii M, Tsunoda T, Matsunaga T. Attenuation of progressive hearing loss in DBA/2J mice by reagents that affect epigenetic modifications is associated with up-regulation of the zinc importer Zip4. PLoS ONE. 2015;10:e0124301 pubmed publisher
    ..The mice were treated from ages 4 to 12 weeks (N ≥ 5), and auditory brainstem response (ABR) thresholds were measured at 8, 16, and 32 kHz...

More Information

Publications138 found, 100 shown here

  1. Gilels F, Paquette S, Beaulac H, Bullen A, White P. Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure. Sci Rep. 2017;7:1054 pubmed publisher
    ..Here we show that Foxo3 is required for auditory function after noise exposure in a mouse model system, measured by ABR. Absent Foxo3, outer hair cells are lost throughout the middle and higher frequencies...
  2. Biamino E, Canale A, Lacilla M, Marinosci A, Dagna F, Genitori L, et al. Prevention and management of hearing loss in syndromic craniosynostosis: A case series. Int J Pediatr Otorhinolaryngol. 2016;85:95-8 pubmed publisher
    ..complete audiologic evaluation including otoscopy, pure-tone audiometry, tympanometry and acoustic reflex testing, ABR, otoacustic emissions, temporal bone High Resolution CT (HRCT) scan...
  3. Chambers A, Salazar J, Polley D. Persistent Thalamic Sound Processing Despite Profound Cochlear Denervation. Front Neural Circuits. 2016;10:72 pubmed publisher
    ..auditory cortex (ACtx) processing and perception recover despite the absence of an auditory brainstem response (ABR) or brainstem acoustic reflexes, and only a partial recovery of sound processing at the level of the inferior ..
  4. Yu F, Hao S, Yang B, Zhao Y, Zhang R, Zhang W, et al. Insulin resistance due to dietary iron overload disrupts inner hair cell ribbon synapse plasticity in male mice. Neurosci Lett. 2015;597:183-8 pubmed publisher
    ..Then, auditory brainstem responses (ABRs) measurements were performed for hearing threshold shifts. After ABR measurements, cochleae were harvested for assessment of the number of IHC ribbon synapses by immunostaining, the ..
  5. Kayaçetin S, Başaranoğlu M. Mallory-Denk bodies: Correlation with steatosis, severity, zonal distribution, and identification with ubiquitin. Turk J Gastroenterol. 2015;26:506-10 pubmed publisher
    ..These findings have demonstrated that the observation of MDB together with ubiquitin positivity will be helpful in the evaluation of the models of diagnosis, staging, and ..
  6. Liu Y, Jolly C, Braun S, Janssen T, Scherer E, Steinhoff J, et al. Effects of a dexamethasone-releasing implant on cochleae: A functional, morphological and pharmacokinetic study. Hear Res. 2015;327:89-101 pubmed publisher
    ..Auditory brainstem response (ABR) and distortion product otoacoustic emissions (DPOAEs) were measured preoperatively and over 6 months ..
  7. Yang Q, Sun G, Cao Z, Yin H, Qi Q, Wang J, et al. The expression of NLRX1 in C57BL/6 mice cochlear hair cells: Possible relation to aging- and neomycin-induced deafness. Neurosci Lett. 2016;616:138-46 pubmed publisher
    ..Hearing thresholds of C57BL/6 mice were measured by auditory brainstem response (ABR)...
  8. Weber B, Whitlock S, He K, Kimbrell B, Derkay C. An evidence based protocol for managing neonatal middle ear effusions in babies who fail newborn hearing screening. Am J Otolaryngol. 2018;39:609-612 pubmed publisher
    ..of a ventilation tube in the presence of a middle ear effusion and had intra-operative auditory brainstem response (ABR) testing or testing at a later date...
  9. Garrison J, Ge C, Che L, Pullum D, Peng G, Khan S, et al. Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic Agents. J Cancer Sci Ther. 2015;7:121-126 pubmed
    ..expression by lentiviral shRNA resulted in increased sensitivity to cisplatin in the resistant breast cancer MDB-MD-231 cell line...
  10. Hurd E, Adams M, Layman W, Swiderski D, Beyer L, Halsey K, et al. Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome. Hear Res. 2011;282:184-95 pubmed publisher
    ..Hearing thresholds by auditory brainstem response (ABR) testing were elevated at 4 and 16 kHz in Chd7(Gt)(/+) mice, and there were reduced distortion product otoacoustic ..
  11. Cai T, Chen Z, Gu X, Zhang X, Yuan W. [Expression of Dynamin in the cochlea of mice of different ages]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015;50:583-6 pubmed
    ..Auditory brainstem response (ABR) was recorded from the Kunming mice on postnatal 3 weeks (young), 10 weeks (adult), and 16 months (aged), 10 mice ..
  12. Kandathil C, Stakhovskaya O, Leake P. Effects of brain-derived neurotrophic factor (BDNF) on the cochlear nucleus in cats deafened as neonates. Hear Res. 2016;342:134-143 pubmed publisher
    ..SQ, SID) starting one day after birth, and continuing for 16-18 days until auditory brainstem response (ABR) testing demonstrated profound bilateral hearing loss...
  13. Di Stadio A, Dipietro L, Ralli M, Meneghello F, Minni A, Greco A, et al. Sudden hearing loss as an early detector of multiple sclerosis: a systematic review. Eur Rev Med Pharmacol Sci. 2018;22:4611-4624 pubmed publisher
    ..Instead, P-SNHL occurred in the late stage of MS (88% of patients). Auditory Brainstem Responses (ABR) were abnormal in all MS patients with S-SNHL...
  14. Sánchez Benito D, Gómez Nieto R, Hernández Noriega S, Murashima A, de Oliveira J, Garcia Cairasco N, et al. Morphofunctional alterations in the olivocochlear efferent system of the genetic audiogenic seizure-prone hamster GASH:Sal. Epilepsy Behav. 2017;71:193-206 pubmed publisher
    ..Our results showed that the GASH:Sal exhibited higher auditory brain response (ABR) thresholds than their controls, as well as absence of distortion-product of otoacoustic emissions (DPOAEs) in a ..
  15. Canales C, Wong A, Gunning P, Housley G, Hardeman E, Palmer S. The role of GTF2IRD1 in the auditory pathology of Williams-Beuren Syndrome. Eur J Hum Genet. 2015;23:774-80 pubmed publisher
    ..of the gene in the inner ear and examined hearing capacity by evaluating the auditory brainstem response (ABR) and the distortion product of otoacoustic emissions (DPOAE)...
  16. Fowler C, Chiasson K, Colman R, Kemnitz J, Beasley T, WEINDRUCH R. Hyperinsulinemia/diabetes, hearing, and aging in the University of Wisconsin calorie restriction monkeys. Hear Res. 2015;328:78-86 pubmed publisher
    ..b>ABR thresholds were 5-8 dB better in the NL group than in the HI-D group, although no significant differences across ..
  17. French S, Mendoza A, Afifiyan N, Tillman B, Vitocruz E, French B. The role of the IL-8 signaling pathway in the infiltration of granulocytes into the livers of patients with alcoholic hepatitis. Exp Mol Pathol. 2017;103:137-140 pubmed publisher
    ..This suggested that IL-8 may be involved in MDB pathogenesis...
  18. Yu F, Hao S, Yang B, Zhao Y, Zhang W, Yang J. Mild Maternal Iron Deficiency Anemia Induces Hearing Impairment Associated with Reduction of Ribbon Synapse Density and Dysregulation of VGLUT3, Myosin VIIa, and Prestin Expression in Young Guinea Pigs. Neurotox Res. 2016;29:594-604 pubmed publisher
    ..On PND 24, pups were examined the hearing function by auditory brainstem response (ABR) and distortion product otoacoustic emission (DPOAE) measurements...
  19. Wick C, Lin S, Yu H, Megerian C, Zheng Q. Treatment of ear and bone disease in the Phex mouse mutant with dietary supplementation. Am J Otolaryngol. 2017;38:44-51 pubmed publisher
    ..At P40, all mice underwent auditory brainstem response (ABR) testing, serum analysis, and temporal bone histologic analysis. Primary outcome was otic capsule mineralization...
  20. Bas E, Bohorquez J, Goncalves S, Perez E, Dinh C, Garnham C, et al. Electrode array-eluted dexamethasone protects against electrode insertion trauma induced hearing and hair cell losses, damage to neural elements, increases in impedance and fibrosis: A dose response study. Hear Res. 2016;337:12-24 pubmed publisher
    ..Hearing thresholds were determined by ABR and CAP recordings in response to a series of defined pure tone stimuli (i.e. 16-0.5 kHz)...
  21. Meehan D, Delimont D, Dufek B, Zallocchi M, Phillips G, Gratton M, et al. Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice. Hear Res. 2016;341:100-108 pubmed publisher
    ..Noise exposure resulted in significantly elevated ABR thresholds in Alport mice relative to wild type littermates...
  22. Adebanjo T, Godfred Cato S, Viens L, Fischer M, Staples J, Kuhnert Tallman W, et al. Update: Interim Guidance for the Diagnosis, Evaluation, and Management of Infants with Possible Congenital Zika Virus Infection - United States, October 2017. MMWR Morb Mortal Wkly Rep. 2017;66:1089-1099 pubmed publisher
    ..using validated tools (3-5), and newborn hearing screen at birth, preferably using auditory brainstem response (ABR) methodology (6)...
  23. Fuentes Santamaría V, Alvarado J, Rodríguez de la Rosa L, Murillo Cuesta S, Contreras J, Juiz J, et al. IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei. Brain Struct Funct. 2016;221:709-34 pubmed publisher
    ..an imbalance between excitation and inhibition, which might be reflected in abnormal auditory brainstem responses (ABR)...
  24. Sheffield A, Gubbels S, Hildebrand M, Newton S, Chiorini J, Di Pasquale G, et al. Viral vector tropism for supporting cells in the developing murine cochlea. Hear Res. 2011;277:28-36 pubmed publisher
    ..Adenovirus showed robust tropism for organ of Corti supporting cells throughout the cochlea but induced increased ABR thresholds indicating ototoxicity...
  25. Tuerdi A, Kinoshita M, Kamogashira T, Fujimoto C, Iwasaki S, Shimizu T, et al. Manganese superoxide dismutase influences the extent of noise-induced hearing loss in mice. Neurosci Lett. 2017;642:123-128 pubmed publisher
    ..The mice were euthanized 14days after noise exposure for examination of the cochlear pathology. Mean ABR thresholds were similarly elevated at all frequencies in both groups 1h after noise exposure, but were ..
  26. Zhang T, Xu Q, Chen F, Han Q, Zhang Y. Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors. Acta Pharmacol Sin. 2004;25:1471-8 pubmed
    ..Selection medium screening identified segments of bone morphogenetic protein-1 (BMP-1), active Bcr-related protein (Abr), and filamin-C as binding partners of alpha1A-AR-CT in yeast cells respectively...
  27. DeLorenzo M, Wu D, Yang K, RUTEL I. RadShield: semiautomated shielding design using a floor plan driven graphical user interface. J Appl Clin Med Phys. 2016;17:509-522 pubmed publisher
    ..of comparing RadShield results with those found by manual shielding design by an American Board of Radiology (ABR)-certified medical physicist for two clinical room situations: two adjacent catheterization labs, and a ..
  28. Celik O, Eskiizmir G, Uz U. A Comparison of Thresholds of Auditory Steady-State Response and Auditory Brainstem Response in Healthy Term Babies. J Int Adv Otol. 2016;12:277-281 pubmed publisher
    ..for each frequency, and detect the best correlated frequencies when compared with the auditory brainstem response (ABR) thresholds in term babies under the age of 12 months. In total, 88 term babies with a mean age of 2...
  29. Meunier S, d Oiron R, Chambost H, Dolimier E, Guillet B. Choice of factor VIII/IX regimen in adolescents and young adults with severe or moderately severe haemophilia. A French national observational study (ORTHem 15-25). Thromb Res. 2017;151:17-22 pubmed publisher
    ..The mean annual bleed rate (ABR) in the OD group (6.33) was higher than in the LTP group (3.07, p<0.001)...
  30. Ouyang J, Pace E, Lepczyk L, Kaufman M, Zhang J, Perrine S, et al. Blast-Induced Tinnitus and Elevated Central Auditory and Limbic Activity in Rats: A Manganese-Enhanced MRI and Behavioral Study. Sci Rep. 2017;7:4852 pubmed publisher
    ..paradigm, while hearing status was assessed with prepulse inhibition (PPI) and auditory brainstem responses (?ABR??s)...
  31. Eren S, Dogan R, Yenigun A, Veyseller B, Tugrul S, Ozturan O, et al. Evaluation of ototoxicity of intratympanic administration of Methotrexate in rats. Int J Pediatr Otorhinolaryngol. 2017;100:132-136 pubmed publisher
    ..At the beginning of the study, Distortion-product otoacoustic emissions (DPOAE) and Auditory brainstem response (ABR) of all rats were measured and then again on the 5th, 10th and 15th day...
  32. Balter J, Haffty B, Dunnick N, Siegel E. Imaging opportunities in radiation oncology. Int J Radiat Oncol Biol Phys. 2011;79:342-7 pubmed publisher
    ..of North America (RSNA), American Association of physicists in Medicine (AAPM), American Board of Radiology (ABR), Radiation Therapy Oncology Group (RTOG), European Society for Therapeutic Radiology and Oncology (ESTRO), and ..
  33. Liu S, Deng L, Yang Y, Yin Z. [Effect of Electroacupuncture on Expression of Catechol-O-methyltransferase in the Inferior Colliculus and Auditory Cortex in Age-related Hearing Loss Guinea Pigs]. Zhen Ci Yan Jiu. 2017;42:145-8 pubmed
    ..After treatment, the latency of auditory brainstem response(ABR) ? wave was measured by a brain-stem evoked potentiometer...
  34. Kim B, Kim J, Park I, Jung J, Suh M, Oh S. Effects of transient auditory deprivation during critical periods on the development of auditory temporal processing. Int J Pediatr Otorhinolaryngol. 2018;104:66-71 pubmed publisher
    ..Outcome measures included changes in auditory brainstem response (ABR), gap prepulse inhibition of the acoustic startle reflex (GPIAS), and gap detection threshold (GDT)...
  35. Kopelovich J, Robinson B, Soken H, Verhoeven K, Kirk J, Goodman S, et al. Acoustic Hearing After Murine Cochlear Implantation: Effects of Trauma and Implant Type. Ann Otol Rhinol Laryngol. 2015;124:931-9 pubmed publisher
    ..A sham surgery group was included as a control. Serial auditory brainstem response (ABR) thresholds and distortion product otoacoustic emissions (DPOAEs) were used to discern effects on hearing over 22 ..
  36. Safe T, Luebke A. Prenatal low dosage dioxin (TCDD) exposure impairs cochlear function resulting in auditory neuropathy. Hear Res. 2016;331:7-12 pubmed publisher
    ..These ABR threshold deficits in mice carrying the Ahb-1 allele parallels the cleft palate incidence to higher TCDD exposures, ..
  37. Kostyanev T, Bonten M, O BRIEN S, Steel H, Ross S, François B, et al. The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance. J Antimicrob Chemother. 2016;71:290-5 pubmed publisher
    Antibiotic resistance (ABR) is a global public health threat. Despite the emergence of highly resistant organisms and the huge medical need for new drugs, the development of antibacterials has slowed to an unacceptable level worldwide...
  38. Berger J, Coomber B, Hill S, Alexander S, Owen W, Palmer A, et al. Effects of the cannabinoid CB1 agonist ACEA on salicylate ototoxicity, hyperacusis and tinnitus in guinea pigs. Hear Res. 2017;356:51-62 pubmed publisher
    ..Salicylate-induced reductions in click-evoked ABR amplitudes were smaller in the presence of ACEA, suggesting that the ototoxic effects of salicylate were less ..
  39. Cho Y, Cunnick J, Yi S, Kaartinen V, Groffen J, Heisterkamp N. Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages. Mol Cell Biol. 2007;27:899-911 pubmed
    Small GTPases of the Rho family are key regulators of phagocytic leukocyte function. Abr and Bcr are homologous, multidomain proteins...
  40. Yan L, Björk P, Butuc R, Gawdzik J, Earley J, Kim G, et al. Beneficial effects of quinoline-3-carboxamide (ABR-215757) on atherosclerotic plaque morphology in S100A12 transgenic ApoE null mice. Atherosclerosis. 2013;228:69-79 pubmed publisher
    ..In this study we tested the efficacy of ABR-215757, a S100 protein binding immuno-modulatory compound to stabilize atherosclerosis in transgenic ApoE null mice ..
  41. Rizvi Z, Hoffman S. Effective Global Action on Antibiotic Resistance Requires Careful Consideration of Convening Forums. J Law Med Ethics. 2015;43 Suppl 3:74-8 pubmed publisher
    Global collective action is needed to address the growing transnational threat of antibiotic resistance (ABR)...
  42. Heeringa A, Stefanescu R, Raphael Y, Shore S. Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult. Neuroscience. 2016;315:114-24 pubmed publisher
    ..Intracochlear kanamycin injections abolished ipsilateral ABR responses in all animals and reduced ipsilateral spiral ganglion neuron densities in animals that were sacrificed ..
  43. Hummel M, Krausgrill C, Perez J, Hagen R, Ernestus R, Matthies C. Management of vestibular schwannoma: A pilot case series with postoperative ABR monitoring. Clin Neurol Neurosurg. 2016;143:139-43 pubmed publisher
    Auditory brainstem response (ABR) monitoring is regularly used in surgery of vestibular schwannoma to achieve hearing preservation. Despite ABR preservation at the end of surgery, there are cases with postoperative deafness...
  44. Hummel M, Perez J, Hagen R, Gelbrich G, Ernestus R, Matthies C. Auditory Monitoring in Vestibular Schwannoma Surgery: Intraoperative Development and Outcome. World Neurosurg. 2016;96:444-453 pubmed publisher
    The auditory brainstem response (ABR) may be a predictor of postoperative cochlear nerve function. In this study, the course of intraoperative ABR monitoring was analyzed to find predictive markers for postoperative hearing function...
  45. Surmeli M, Sürmeli R, Deveci I, Onder S, Yalçın A, Oysu C. Correlation between cVEMP and ABR for the Evaluation of Vestibular Migraine. J Int Adv Otol. 2016;12:326-331 pubmed publisher
    ..study, we aimed to determine the changes in vestibular myogenic potential (cVEMP) and auditory brainstem response (ABR) in patients with VM and migraine...
  46. Cui J, Zhu B, Fang G, Smith E, Brauth S, Tang Y. Effect of the Level of Anesthesia on the Auditory Brainstem Response in the Emei Music Frog (Babina daunchina). PLoS ONE. 2017;12:e0169449 pubmed publisher
    Anesthesia is known to affect the auditory brainstem response (ABR) in mice, rats, birds and lizards. The present study investigated how the level of anesthesia affects ABR recordings in an amphibian species, Babina daunchina...
  47. Casteil L, Viquesnel A, Favier V, Guignard N, Blanchet C, Mondain M. Study of the efficacy of melatonin for auditory brainstem response (ABR) testing in children. Eur Ann Otorhinolaryngol Head Neck Dis. 2017;134:373-375 pubmed publisher
    ..the efficacy of oral melatonin to induce sedation (natural sleep) while measuring auditory brainstem responses (ABR) in children with suspected hearing loss by calculating the ABR success rate with the use of melatonin, the ..
  48. Milon B, Mitra S, Song Y, Margulies Z, Casserly R, Drake V, et al. The impact of biological sex on the response to noise and otoprotective therapies against acoustic injury in mice. Biol Sex Differ. 2018;9:12 pubmed publisher
    ..3 kHz). Hearing was assessed by measuring auditory brainstem responses (ABR) at 8, 16, 24, and 32 kHz, 1 week before, as well as at 24 h and 15-21 days following exposure (..
  49. Yamaji M, Suwa Y, Shimokawa R, Paris C, Miranda M. Photochemical reactions of halogenated aromatic 1,3-diketones in solution studied by steady state, one- and two-color laser flash photolyses. Photochem Photobiol Sci. 2015;14:1673-84 pubmed publisher
    ..AB in acetonitrile and ethanol provided a transient absorption spectrum ascribable to the Avobenzone radical (ABR) produced by debromination as the initial intermediate, followed by the AB formation in ethanol...
  50. Hoffman S, Røttingen J, Frenk J. International Law Has a Role to Play in Addressing Antibiotic Resistance. J Law Med Ethics. 2015;43 Suppl 3:65-7 pubmed publisher
    ..legal agreement is needed for any of today's global health challenges, it would be antibiotic resistance (ABR)...
  51. Myint A, White C, Ohmen J, Li X, Wang J, Lavinsky J, et al. Large-scale phenotyping of noise-induced hearing loss in 100 strains of mice. Hear Res. 2016;332:113-120 pubmed publisher
    A cornerstone technique in the study of hearing is the Auditory Brainstem Response (ABR), an electrophysiologic technique that can be used as a quantitative measure of hearing function...
  52. Kelleher M, Rolen M, Bokhari S. Reshaping the emergency radiology call experience after the merger of two programs: the Yale experience. Emerg Radiol. 2016;23:63-6 pubmed publisher
    ..These rotations allow third year residents to have more "call-free" weeks prior to the ABR core exam...
  53. Valenzuela D, Kumar D, Atkins C, Beers A, Kozak F, Chadha N. Chloral hydrate sedation for auditory brainstem response (ABR) testing in children: Safety and effectiveness. Int J Pediatr Otorhinolaryngol. 2016;83:175-8 pubmed publisher
    The auditory brainstem response (ABR) test is used to identify hearing loss and measure hearing thresholds of infants and children who cannot be tested using standard behavioral hearing testing methods...
  54. Jáuregui E, Akil O, Acevedo C, Hall Glenn F, Tsai B, Bale H, et al. Parallel mechanisms suppress cochlear bone remodeling to protect hearing. Bone. 2016;89:7-15 pubmed publisher
    ..bone revealed no differences in these markers, nor hearing loss as measured by auditory brainstem response (ABR) or distortion product oto-acoustic emissions (DPOAEs), between wild type and MMP13(-/-) mice...
  55. Cargnelutti M, Coser P, Biaggio E. LS CE-Chirp® vs. Click in the neuroaudiological diagnosis by ABR. Braz J Otorhinolaryngol. 2017;83:313-317 pubmed publisher
    ..its association with the amplitude of wave I, and the interaural difference V-V in the auditory brainstem response (ABR) using Click and LS CE-Chirp® stimuli to determine whether the responses evoked by LS CE-Chirp®
  56. Olgun Y, Kirkim G, Altun Z, Aktas S, Kolatan E, Kiray M, et al. Protective Effect of Korean Red Ginseng on Cisplatin Ototoxicity: Is It Effective Enough?. J Int Adv Otol. 2016;12:177-183 pubmed publisher
    ..Baseline distortion product otoacoustic emissions (DPOAEs) and auditory brainstem response (ABR) measurements were obtained. In groups I, II, and III, only saline, KRG, and CDDP, respectively, were given...
  57. Fan Y, Zhang Y, Wu R, Chen X, Zhang Y, Chen X, et al. miR-431 is involved in regulating cochlear function by targeting Eya4. Biochim Biophys Acta. 2016;1862:2119-2126 pubmed publisher
    ..However, a comparison of auditory brain stem responses (ABRs) in Tg and Wt mice showed that ABR thresholds were significantly higher in Tg mice than in Wt mice...
  58. Land R, Burghard A, Kral A. The contribution of inferior colliculus activity to the auditory brainstem response (ABR) in mice. Hear Res. 2016;341:109-118 pubmed publisher
    In mice, the auditory brainstem response (ABR) is frequently used to assess hearing status in transgenic hearing models. The diagnostic value of the ABR depends on knowledge about the anatomical sources of its characteristic waves...
  59. Afifi P, Elsanadiky H. Audiological findings in children with ataxia-telangiectasia (A-T) syndrome. Int J Pediatr Otorhinolaryngol. 2017;92:94-98 pubmed publisher
    ..testing, tympanometry, acoustic reflexes, Otoacoustic Emissions (OAEs) and Auditory Brainstem Responses (ABR) were done for all of them...
  60. Liu Y, Lam S. Sequence Effect on the Formation of DNA Minidumbbells. J Phys Chem B. 2017;121:10338-10343 pubmed publisher
    The DNA minidumbbell (MDB) is a recently identified non-B structure. The reported MDBs contain two TTTA, CCTG, or CTTG type II loops...
  61. Dequesada I, Chokshi F, Mullins M, Duszak R. Practice Management and Health Policy Education in Radiology: An Emerging Imperative. J Am Coll Radiol. 2015;12:1085-92 pubmed publisher
    ..education in health policy and practice management, detail the history and requirements of the ACGME and the ABR Healthcare Economics Milestone Project, and outline mechanisms by which radiology residency programs can comply ..
  62. Holmes W, Liao L, Bement W, Edelstein Keshet L. Modeling the roles of protein kinase Cβ and η in single-cell wound repair. Mol Biol Cell. 2015;26:4100-8 pubmed publisher
    ..We show that PKCβ likely affects the magnitude of positive Rho-Abr feedback, whereas PKCη acts on Cdc42 inactivation...
  63. Zhu M, He G, Li H, Xie M, Gyanwali B, Xie L, et al. The effects of the auditory brainstem response before and after fluoro-gold injection in medial geniculate body. Neuro Endocrinol Lett. 2015;36:779-86 pubmed
    ..pathway in tree shrews by fluoro-gold (FG) but also to elucidate the effects of the auditory brainstem response (ABR) before and after FG injection. FG was injected into the medial geniculate body (MGB) of experimental group (n=10)...
  64. Li J, Shi E, Antwi P, Leu S. Modeling the performance of an anaerobic baffled reactor with the variation of hydraulic retention time. Bioresour Technol. 2016;214:477-486 pubmed publisher
    ..was developed to predict volatile fatty acids (VFAs), chemical oxygen demand (CODCr) and biogas in a 4-compartment ABR operated with variable hydraulic retention time (HRT)...
  65. Michel F, Jørgensen K. Comparison of threshold estimation in infants with hearing loss or normal hearing using auditory steady-state response evoked by narrow band CE-chirps and auditory brainstem response evoked by tone pips. Int J Audiol. 2017;56:99-105 pubmed publisher
    The objective of this study is to compare air-conduction thresholds obtained with ASSR evoked by narrow band (NB) CE-chirps and ABR evoked by tone pips (tpABR) in infants with various degrees of hearing loss.
  66. Chang M, Gwon T, Lee H, Lee J, Oh S, Kim S, et al. The effect of systemic lipoic acid on hearing preservation after cochlear implantation via the round window approach: A guinea pig model. Eur J Pharmacol. 2017;799:67-72 pubmed publisher
    ..Threshold shifts changed with frequency but not time. At 2kHz, ABR threshold shifts were statistically significantly lower in the lipoic acid group than the control group...
  67. Jiang H, Nie H, Ding J, Stinner W, Sun K, Zhou H. The startup performance and microbial distribution of an anaerobic baffled reactor (ABR) treating medium-strength synthetic industrial wastewater. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2017;:1-9 pubmed publisher
    In this study, an anaerobic baffled reactor (ABR) with seven chambers was applied to treat medium-strength synthetic industrial wastewater (MSIW). The performance of startup and shock test on treating MSIW was investigated...
  68. Mastronardi L, Di Scipio E, Cacciotti G, Roperto R. Vestibular schwannoma and hearing preservation: Usefulness of level specific CE-Chirp ABR monitoring. A retrospective study on 25 cases with preoperative socially useful hearing. Clin Neurol Neurosurg. 2018;165:108-115 pubmed publisher
    ..postoperative HP with reference to tumor size in patients operated on with Level Specific (LS)-CE-Chirp® ABR monitoring...
  69. Wu S, Kuan V, Tzeng Y, Schuyler S, Juang Y. The anaphase-promoting complex works together with the SCF complex for proteolysis of the S-phase cyclin Clb6 during the transition from G1 to S phase. Fungal Genet Biol. 2016;91:6-19 pubmed publisher
    ..Mutations in the KEN box (mkb) and/or the destruction box (mdb) enhanced Clb6 stability in G1...
  70. Sturza J, Silver M, Xu L, Li M, Mai X, Xia Y, et al. Prenatal exposure to multiple pesticides is associated with auditory brainstem response at 9months in a cohort study of Chinese infants. Environ Int. 2016;92-93:478-85 pubmed publisher
    ..Auditory brainstem response (ABR) and pesticide data were available for 27 healthy, full-term 9-month-old infants participating in a larger study of ..
  71. Zakaria M, Jalaei B. Test-retest reliability of speech-evoked auditory brainstem response in healthy children at a low sensation level. Int J Pediatr Otorhinolaryngol. 2017;102:28-31 pubmed publisher
    ..The stability of speech-evoked auditory brainstem response (speech-ABR) when tested over time has been reported but the literature is limited...
  72. Pawar S. Computational fluid dynamics (CFD) analysis of airlift bioreactor: effect of draft tube configurations on hydrodynamics, cell suspension, and shear rate. Bioprocess Biosyst Eng. 2018;41:31-45 pubmed publisher
    The biomass productivity of microalgae cells mainly depends on the hydrodynamics of airlift bioreactor (ABR)...
  73. Heisterkamp N, Morris C, Groffen J. ABR, an active BCR-related gene. Nucleic Acids Res. 1989;17:8821-31 pubmed
    ..Here we report the molecular cloning of one of these loci, for which we propose the name ABR. In contrast with the other BCR-related genes studied to date, ABR represents a functionally active gene and ..
  74. Kaartinen V, Nagy A, Gonzalez Gomez I, Groffen J, Heisterkamp N. Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs. Dev Dyn. 2002;223:517-25 pubmed
    ..To determine the biological function of two closely related GTPase activating proteins for the Cdc42/Rac GTPases, Abr and Bcr, we generated a mouse strain deficient in both of these proteins...
  75. Zhang J, Liu Z, Chang A, Fang J, Men Y, Tian Y, et al. Abnormal mRNA splicing but normal auditory brainstem response (ABR) in mice with the prestin (SLC26A5) IVS2-2A>G mutation. Mutat Res. 2016;790:1-7 pubmed publisher
    ..The homozygous Slc26a5 mutant mice were viable and fertile and displayed normal hearing sensitivity by ABR threshold analysis...
  76. Jamesdaniel S, Rathinam R, Neumann W. Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity. Redox Biol. 2016;10:257-265 pubmed publisher
    ..Finally, auditory brainstem responses (ABR) recorded from CBA/J mice indicated that co-treatment with SRI110 mitigated cisplatin-induced hearing loss...
  77. Popelar J, Diaz Gomez M, Lindovský J, Rybalko N, Burianova J, Oohashi T, et al. Resveratrol alleviates ethanol-induced hormonal and metabolic disturbances in the rat. Physiol Res. 2017;: pubmed
    ..Hearing thresholds in 2-month-old WT mice, based on the auditory brainstem response (ABR) recordings, were significantly lower at high frequencies than in KO mice...
  78. Matas C, Samelli A, Magliaro F, Segurado A. Audiological and electrophysiological alterations in HIV-infected individuals subjected or not to antiretroviral therapy. Braz J Otorhinolaryngol. 2017;: pubmed publisher
    ..25-8kHz, extended high frequencies at 9-20kHz, electrophysiological tests (Auditory Brainstem Response - ABR, Middle Latency Responses - MLR, Cognitive Potential - P300)...
  79. Gauvin D, Yoder J, Koch A, Zimmermann Z, Tapp R. Down for the count: The critical endpoint in ototoxicity remains the cytocochleogram. J Pharmacol Toxicol Methods. 2017;88:123-129 pubmed publisher
    ..enabling ototoxicity study designs: 1) functional acoustic threshold measurements (Auditory Brainstem Respsonse, ABR); 2) otohistopathology and 3) cytocochleograms...
  80. Xu S, Jiang C, Ma S, Wu S, Bai Z, Zhuang G, et al. The performance and archaeal community shifts in a modified anaerobic baffled reactor treating sweet potato starch wastewater at ambient temperatures. Sci Rep. 2017;7:14734 pubmed publisher
    ..Finally, the net energy gains analysis at mesophilic, thermophilic, and ambient temperature revealed that modified ABR at ambient temperature was not only economical but also profitable and could generated 3...
  81. Hauser S, Burton J, Mercer E, Ramachandran R. Effects of noise overexposure on tone detection in noise in nonhuman primates. Hear Res. 2018;357:33-45 pubmed publisher
    ..Physiological measurements showed elevated auditory brainstem response (ABR) thresholds and absent distortion product otoacoustic emissions (DPOAEs) post-exposure relative to pre-exposure...
  82. Masouminia M, Samadzadeh S, Mendoza A, French B, Tillman B, French S. Upregulation of autophagy components in alcoholic hepatitis and nonalcoholic steatohepatitis. Exp Mol Pathol. 2016;101:81-8 pubmed publisher
    ..studies autophagy, as an intracellular pathway which degrades misfolded and damaged protein, and Mallory-Denk Body (MDB) formation have been shown to be protective mechanisms against stress such as alcoholic hepatitis...
  83. Marie A, Larroze Chicot P, Cosnier Pucheu S, González González S. Senescence-accelerated mouse prone 8 (SAMP8) as a model of age-related hearing loss. Neurosci Lett. 2017;656:138-143 pubmed publisher
    ..In this study, we determined the influence of age on auditory brainstem response (ABR) and the distortion product otoacoustic emissions (DPOAE) in the premature senescence mouse model SAMP8 for five ..
  84. Nowotny M, Kiefer L, Andre D, Fabrizius A, Hankeln T, Reuss S. Hearing Without Neuroglobin. Neuroscience. 2017;366:138-148 pubmed publisher
    ..were moderately augmented in the range of 5-18?kHz, reaching statistical significance at 8 and 10?kHz, while the ABR thresholds were not different between groups...
  85. Miron O, Beam A, Kohane I. Auditory brainstem response in infants and children with autism spectrum disorder: A meta-analysis of wave V. Autism Res. 2017;: pubmed publisher
    Infants with autism spectrum disorder (ASD) were recently found to have prolonged auditory brainstem response (ABR); however, at older ages, findings are contradictory...
  86. Norrix L, VELENOVSKY D. Unraveling the Mystery of Auditory Brainstem Response Corrections: The Need for Universal Standards. J Am Acad Audiol. 2017;28:950-960 pubmed publisher
    The auditory brainstem response (ABR) is used to estimate behavioral hearing thresholds in infants and difficult-to-test populations...
  87. Chuang T, Xu X, Kaartinen V, Heisterkamp N, Groffen J, Bokoch G. Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family. Proc Natl Acad Sci U S A. 1995;92:10282-6 pubmed
    ..The Abr protein is very similar to Bcr but lacks a structural domain which may influence its biological regulatory ..
  88. Shiraiwa Y, Daikoku E, Saito M, Yamashita Y, Abe T, Ono F, et al. Measurements of ionic concentrations along with endocochlear potential in wild-type and claudin 14 knockout mice. Auris Nasus Larynx. 2018;45:421-426 pubmed publisher
    ..We used the Cldn14-/- from 3 weeks of age, in which the auditory brain responses (ABR) was severely diminished...
  89. Roszak J, Domeradzka Gajda K, Smok Pieniążek A, Kozajda A, Spryszyńska S, Grobelny J, et al. Genotoxic effects in transformed and non-transformed human breast cell lines after exposure to silver nanoparticles in combination with aluminium chloride, butylparaben or di-n-butylphthalate. Toxicol In Vitro. 2017;45:181-193 pubmed publisher
    In the present study genotoxic effects after combined exposure of human breast cell lines (MCF-10A, MCF-7 and MDB-MB-231) to silver nanoparticles (AgNP, citrate stabilized, 15 and 45nm by STEM, Ag15 and Ag45, respectively) with aluminium ..
  90. Chen C, Baker J, Nichol M. Economic Burden of Illness among Persons with Hemophilia B from HUGS Vb: Examining the Association of Severity and Treatment Regimens with Costs and Annual Bleed Rates. Value Health. 2017;20:1074-1082 pubmed publisher
    To determine US societal burden of illness, including direct and indirect costs and annual bleed rate (ABR), for persons with hemophilia B (HB), a rare and debilitating genetic disorder, and to examine associations of hemophilia severity ..
  91. Schneider M, Griffin P, Tyagi S, Flannery M, Dayalan S, Gladman S, et al. Establishing a distributed national research infrastructure providing bioinformatics support to life science researchers in Australia. Brief Bioinform. 2017;: pubmed publisher
    EMBL Australia Bioinformatics Resource (EMBL-ABR) is a developing national research infrastructure, providing bioinformatics resources and support to life science and biomedical researchers in Australia...
  92. Zorzi V, Paciello F, Ziraldo G, Peres C, Mazzarda F, Nardin C, et al. Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function. Front Mol Neurosci. 2017;10:379 pubmed publisher
    ..outer hair cell-based "cochlear amplifier" and cochlear nerve function, analyzed by auditory brainstem response (ABR) and distortion product otoacoustic emission (DPOAE) recordings, were normal in Panx1+/- and Panx1-/- ..