AAMP

Summary

Gene Symbol: AAMP
Description: angio associated migratory cell protein
Alias: angio-associated migratory cell protein
Species: human
Products:     AAMP

Top Publications

  1. Plotzki E, Heinrichs G, Kubícková B, Ulrich R, Denner J. Microbiological characterization of a newly established pig breed, Aachen Minipigs. Xenotransplantation. 2016;23:159-67 pubmed publisher
    ..Here, we characterize another minipig, the Aachen Minipig (AaMP), a pig breed recently established close to the town Aachen in Germany...
  2. Pali Schöll I, Jensen Jarolim E. The concept of allergen-associated molecular patterns (AAMP). Curr Opin Immunol. 2016;42:113-118 pubmed publisher
    ..The accumulated evidence for repetitive epitope display by allergens suggests the existence of allergen-associated molecular patterns. ..
  3. Beckner M, Krutzsch H, Stracke M, Williams S, Gallardo J, Liotta L. Identification of a new immunoglobulin superfamily protein expressed in blood vessels with a heparin-binding consensus sequence. Cancer Res. 1995;55:2140-9 pubmed
    A novel immunoglobulin-type protein expressed in blood vessels has been identified. The cDNA for AAMP (angio-associated, migratory cell protein) was first isolated from a human melanoma cell line during a search for motility-associated ..
  4. Beckner M, Peterson V, Moul D. Angio-associated migratory cell protein is expressed as an extracellular protein by blood-vessel-associated mesenchymal cells. Microvasc Res. 1999;57:347-52 pubmed
  5. Beckner M, Jagannathan S, Peterson V. Extracellular angio-associated migratory cell protein plays a positive role in angiogenesis and is regulated by astrocytes in coculture. Microvasc Res. 2002;63:259-69 pubmed
    The extracellular form of angio-associated migratory cell protein (AAMP), a recently discovered protein, plays a positive role in angiogenesis and can be regulated by astrocytes...
  6. Vogt F, Zernecke A, Beckner M, Krott N, Bosserhoff A, Hoffmann R, et al. Blockade of angio-associated migratory cell protein inhibits smooth muscle cell migration and neointima formation in accelerated atherosclerosis. J Am Coll Cardiol. 2008;52:302-11 pubmed publisher
    The aim of this study was to elucidate the role of angio-associated migratory cell protein (AAMP) for the migration of vascular smooth muscle cells (SMCs) and for the development of neointimal hyperplasia after vascular injury...
  7. Bielig H, Zurek B, Kutsch A, Menning M, Philpott D, Sansonetti P, et al. A function for AAMP in Nod2-mediated NF-kappaB activation. Mol Immunol. 2009;46:2647-54 pubmed publisher
    The WD40 repeat containing angio-associated migratory cell protein (AAMP) was identified as a new binding partner of the human nucleotide-binding domain, leucine rich repeat containing (NLR) family member Nod2 in a yeast two-hybrid screen...
  8. Reid H, Wikström K, Kavanagh D, Mulvaney E, Kinsella B. Interaction of angio-associated migratory cell protein with the TP? and TP? isoforms of the human thromboxane A? receptor. Cell Signal. 2011;23:700-17 pubmed publisher
    ..Herein, angio-associated migratory cell protein (AAMP) was identified as a novel interacting partner of both TP? and TP? through an interaction dependent on common (..
  9. Zeng Z, Shaffer J, Wang X, Feingold E, Weeks D, Lee M, et al. Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition. J Dent Res. 2013;92:432-7 pubmed publisher
    ..g., CXCR1 and CXCR2, p value = 1.9E-6). This study supports the notion that genes differentially affect cariogenesis across the surfaces of the permanent dentition, and nominates several novel genes for investigation. ..
  10. Yin Y, Sanders A, Jiang W. The impact of angio-associated migratory cell protein (AAMP) on breast cancer cells in vitro and its clinical significance. Anticancer Res. 2013;33:1499-509 pubmed
    Angio-associated migratory cell protein (AAMP), which belongs to the immunoglobulin superfamily, was found to be expressed in different human cell lines and exhibited a predominant cytosolic localization in epithelial cells...

Detail Information

Publications15

  1. Plotzki E, Heinrichs G, Kubícková B, Ulrich R, Denner J. Microbiological characterization of a newly established pig breed, Aachen Minipigs. Xenotransplantation. 2016;23:159-67 pubmed publisher
    ..Here, we characterize another minipig, the Aachen Minipig (AaMP), a pig breed recently established close to the town Aachen in Germany...
  2. Pali Schöll I, Jensen Jarolim E. The concept of allergen-associated molecular patterns (AAMP). Curr Opin Immunol. 2016;42:113-118 pubmed publisher
    ..The accumulated evidence for repetitive epitope display by allergens suggests the existence of allergen-associated molecular patterns. ..
  3. Beckner M, Krutzsch H, Stracke M, Williams S, Gallardo J, Liotta L. Identification of a new immunoglobulin superfamily protein expressed in blood vessels with a heparin-binding consensus sequence. Cancer Res. 1995;55:2140-9 pubmed
    A novel immunoglobulin-type protein expressed in blood vessels has been identified. The cDNA for AAMP (angio-associated, migratory cell protein) was first isolated from a human melanoma cell line during a search for motility-associated ..
  4. Beckner M, Peterson V, Moul D. Angio-associated migratory cell protein is expressed as an extracellular protein by blood-vessel-associated mesenchymal cells. Microvasc Res. 1999;57:347-52 pubmed
  5. Beckner M, Jagannathan S, Peterson V. Extracellular angio-associated migratory cell protein plays a positive role in angiogenesis and is regulated by astrocytes in coculture. Microvasc Res. 2002;63:259-69 pubmed
    The extracellular form of angio-associated migratory cell protein (AAMP), a recently discovered protein, plays a positive role in angiogenesis and can be regulated by astrocytes...
  6. Vogt F, Zernecke A, Beckner M, Krott N, Bosserhoff A, Hoffmann R, et al. Blockade of angio-associated migratory cell protein inhibits smooth muscle cell migration and neointima formation in accelerated atherosclerosis. J Am Coll Cardiol. 2008;52:302-11 pubmed publisher
    The aim of this study was to elucidate the role of angio-associated migratory cell protein (AAMP) for the migration of vascular smooth muscle cells (SMCs) and for the development of neointimal hyperplasia after vascular injury...
  7. Bielig H, Zurek B, Kutsch A, Menning M, Philpott D, Sansonetti P, et al. A function for AAMP in Nod2-mediated NF-kappaB activation. Mol Immunol. 2009;46:2647-54 pubmed publisher
    The WD40 repeat containing angio-associated migratory cell protein (AAMP) was identified as a new binding partner of the human nucleotide-binding domain, leucine rich repeat containing (NLR) family member Nod2 in a yeast two-hybrid screen...
  8. Reid H, Wikström K, Kavanagh D, Mulvaney E, Kinsella B. Interaction of angio-associated migratory cell protein with the TP? and TP? isoforms of the human thromboxane A? receptor. Cell Signal. 2011;23:700-17 pubmed publisher
    ..Herein, angio-associated migratory cell protein (AAMP) was identified as a novel interacting partner of both TP? and TP? through an interaction dependent on common (..
  9. Zeng Z, Shaffer J, Wang X, Feingold E, Weeks D, Lee M, et al. Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition. J Dent Res. 2013;92:432-7 pubmed publisher
    ..g., CXCR1 and CXCR2, p value = 1.9E-6). This study supports the notion that genes differentially affect cariogenesis across the surfaces of the permanent dentition, and nominates several novel genes for investigation. ..
  10. Yin Y, Sanders A, Jiang W. The impact of angio-associated migratory cell protein (AAMP) on breast cancer cells in vitro and its clinical significance. Anticancer Res. 2013;33:1499-509 pubmed
    Angio-associated migratory cell protein (AAMP), which belongs to the immunoglobulin superfamily, was found to be expressed in different human cell lines and exhibited a predominant cytosolic localization in epithelial cells...
  11. Hanoun N, Fritsch S, Gayet O, Gigoux V, Cordelier P, Dusetti N, et al. The E3 ubiquitin ligase thyroid hormone receptor-interacting protein 12 targets pancreas transcription factor 1a for proteasomal degradation. J Biol Chem. 2014;289:35593-604 pubmed publisher
    ..Our data suggest that an increase in TRIP12 expression can play a part in PTF1a down-regulation and indicate that PTF1a/TRIP12 functional interaction may regulate pancreatic epithelial cell homeostasis. ..
  12. Hu J, Qiu J, Zheng Y, Zhang T, Yin T, Xie X, et al. AAMP Regulates Endothelial Cell Migration and Angiogenesis Through RhoA/Rho Kinase Signaling. Ann Biomed Eng. 2016;44:1462-74 pubmed publisher
    Angiogenesis is a complicated process including endothelial cell proliferation, migration and tube formation. AAMP plays a role in regulating cell migration of multiple cell types...
  13. Yan J, Han Z, Qu Y, Yao C, Shen D, Tai G, et al. Structure elucidation and immunomodulatory activity of a ?-glucan derived from the fruiting bodies of Amillariella mellea. Food Chem. 2018;240:534-543 pubmed publisher
    A novel polysaccharide AAMP-A70 (5.6kDa) has been purified from the fruiting bodies of Amillariella mellea...
  14. Beckner M, Krutzsch H, Klipstein S, Williams S, Maguire J, Doval M, et al. AAMP, a newly identified protein, shares a common epitope with alpha-actinin and a fast skeletal muscle fiber protein. Exp Cell Res. 1996;225:306-14 pubmed
    b>AAMP (angio-associated migratory cell protein) shares a common epitope with alpha-actinin and a fast-twitch skeletal muscle fiber protein. An antigenic peptide, P189, derived from the sequence of AAMP was synthesized...
  15. Morozov V, Heinrichs G, Denner J. Effective Detection of Porcine Cytomegalovirus Using Non-Invasively Taken Samples from Piglets. Viruses. 2017;9: pubmed publisher
    ..Sera, ear biopsies, as well as oral and anal swabs were collected from ten 10-day-old Aachen minipigs (AaMP) and tested for PCMV using sensitive nested polymerase chain reaction (PCR) as well as uniplex and duplex real-time ..