Gene Symbol: halorhodopsin
Description: halorhodopsin
Alias: VNG0180G
Species: Halobacterium sp. NRC-1

Top Publications

  1. Oesterhelt D. The structure and mechanism of the family of retinal proteins from halophilic archaea. Curr Opin Struct Biol. 1998;8:489-500 pubmed
  2. Blanck A, Oesterhelt D. The halo-opsin gene. II. Sequence, primary structure of halorhodopsin and comparison with bacteriorhodopsin. EMBO J. 1987;6:265-73 pubmed
    The gene for the protein moiety of the light-driven chloride pump halorhodopsin (HR), hop gene, was sequenced and the primary structure of the protein derived thereof. The gene has a GC content of 67% and codes for 274 amino acids...
  3. Kolbe M, Besir H, Essen L, Oesterhelt D. Structure of the light-driven chloride pump halorhodopsin at 1.8 A resolution. Science. 2000;288:1390-6 pubmed
    b>Halorhodopsin, an archaeal rhodopsin ubiquitous in Haloarchaea, uses light energy to pump chloride through biological membranes...
  4. Havelka W, Henderson R, Oesterhelt D. Three-dimensional structure of halorhodopsin at 7 A resolution. J Mol Biol. 1995;247:726-38 pubmed publisher
    Two-dimensional crystalline patches containing the light-driven chloride pump, halorhodopsin, appear to form spontaneously in the cell membrane of an overproducing strain of Halobacterium...
  5. Schreiner M, Schlesinger R, Heberle J, Niemann H. Crystal structure of Halobacterium salinarum halorhodopsin with a partially depopulated primary chloride-binding site. Acta Crystallogr F Struct Biol Commun. 2016;72:692-9 pubmed publisher
    The transmembrane pump halorhodopsin in halophilic archaea translocates chloride ions from the extracellular to the cytoplasmic side upon illumination...
  6. Gmelin W, Zeth K, Efremov R, Heberle J, Tittor J, Oesterhelt D. The crystal structure of the L1 intermediate of halorhodopsin at 1.9 angstroms resolution. Photochem Photobiol. 2007;83:369-77 pubmed
    The mutant T203V of the light driven chloride pump halorhodopsin from Halobacterium salinarum was crystallized and the X-ray structure was solved at 1.6 angstroms resolution...