Gene Symbol: mdh
Description: malate dehydrogenase
Species: Haemophilus influenzae Rd KW20
Feil E, Holmes E, Bessen D, Chan M, Day N, Enright M, et al
. Recombination within natural populations of pathogenic bacteria: short-term empirical estimates and long-term phylogenetic consequences. Proc Natl Acad Sci U S A. 2001;98:182-7 pubmed publisher
..The impact of recombination therefore varies between bacterial species but in many species is sufficient to obliterate the phylogenetic signal in gene trees...
O Neill J, St Geme J, Cutter D, Adderson E, Anyanwu J, Jacobs R, et al
. Invasive disease due to nontypeable Haemophilus influenzae among children in Arkansas. J Clin Microbiol. 2003;41:3064-9 pubmed
..influenzae may have more invasive potential, especially in young children and patients with underlying medical conditions. At this point, the specific factors that contribute to enhanced virulence remain unclear...
Cody A, Field D, Feil E, Stringer S, Deadman M, Tsolaki A, et al
. High rates of recombination in otitis media isolates of non-typeable Haemophilus influenzae. Infect Genet Evol. 2003;3:57-66 pubmed
..These findings provide a population based foundation for a better understanding of the role of NTHi LPS as a virulence factor and its potential as a candidate vaccine...
Platonov A, Mironov K, Iatsyshina S, Koroleva I, Platonova O, Gushchin A, et al
. [Multilocus sequence-typing for characterization of Moscow strains of Haemophilus influenzae type b]. Mol Gen Mikrobiol Virusol. 2003;:21-5 pubmed
..influenzae, type b (Hib) bacteria, were genotyped by multilocus sequence typing (MLST) using 5 loci (adk, fucK, mdh, pgi, recA)...