gspL

Summary

Gene Symbol: gspL
Description: general secretory pathway component, cryptic
Alias: ECK3320, JW5705, yheK
Species:

Top Publications

  1. ncbi The complete general secretory pathway in gram-negative bacteria
    A P Pugsley
    Unité de Génétique Moléculaire, Institut Pasteur, Paris, France
    Microbiol Rev 57:50-108. 1993
  2. ncbi Type IV-like pili formed by the type II secreton: specificity, composition, bundling, polar localization, and surface presentation of peptides
    Guillaume Vignon
    Unité de Génétique Moléculaire CNRS URA 2172, Institut Pasteur, Paris, France
    J Bacteriol 185:3416-28. 2003
  3. ncbi Involvement of the twin-arginine translocation system in protein secretion via the type II pathway
    R Voulhoux
    Laboratoire d Ingenierie des Systemes Macromoleculaires, UPR9027, IBSM CNRS, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    EMBO J 20:6735-41. 2001
  4. ncbi Biology of type II secretion
    M Sandkvist
    Department of Biochemistry, American Red Cross, Jerome H Holland Laboratory, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
    Mol Microbiol 40:271-83. 2001
  5. ncbi An inner membrane platform in the type II secretion machinery of Gram-negative bacteria
    B Py
    Laboratoire de Chimie Bacterienne, IBSM, CNRS, 31 Chemin Joseph Aiguier, Marseille Cedex 20, 13402, France
    EMBO Rep 2:244-8. 2001
  6. ncbi Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion
    O Francetic
    Unité de Génétique moléculaire and Unité de Physicochimie de Macromolécules biologiques, Centre National de la Recherche scientifique URA1773, Institut Pasteur, 25 rue du Dr Roux, 75734 Paris, Cedex 15, France
    EMBO J 19:6697-703. 2000
  7. ncbi Protein secretion in Escherichia coli K-12: dead or alive?
    A P Pugsley
    Unité de Génétique Moléculaire, CNRS URA 1773, Institut Pasteur, Paris, France
    Cell Mol Life Sci 54:347-52. 1998
  8. ncbi The cryptic general secretory pathway (gsp) operon of Escherichia coli K-12 encodes functional proteins
    O Francetic
    Unité de Génétique Moléculaire, Centre National de la Recherche Scientifique Unité de Recherche Associée 1149, Institut Pasteur, Paris, France
    J Bacteriol 178:3544-9. 1996
  9. ncbi The underlying mechanisms of type II protein secretion
    Alain Filloux
    Laboratoire d Ingenierie des Systemes Macromoleculaires, CNRS IBSM UPR9027, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    Biochim Biophys Acta 1694:163-79. 2004
  10. ncbi Multiple interactions between pullulanase secreton components involved in stabilization and cytoplasmic membrane association of PulE
    O M Possot
    Unité de Génétique Moléculaire, CNRS, URA 1773, Institut Pasteur, 75724 Paris, Cedex 15, France
    J Bacteriol 182:2142-52. 2000

Scientific Experts

  • A Filloux
  • A P Pugsley
  • M Sandkvist
  • B Py
  • O Francetic
  • Guillaume Vignon
  • R Voulhoux
  • O M Possot
  • Marie Christine Prevost
  • Rolf Köhler
  • Pascal Roux
  • Eric Larquet
  • Stéphanie Giroux
  • B Ize
  • A Lazdunski
  • G Ball
  • M L Vasil
  • L F Wu
  • F Ebel
  • D Belin
  • C Badaut
  • N Bomchil
  • G Vignon

Detail Information

Publications11

  1. ncbi The complete general secretory pathway in gram-negative bacteria
    A P Pugsley
    Unité de Génétique Moléculaire, Institut Pasteur, Paris, France
    Microbiol Rev 57:50-108. 1993
    ..This recently discovered branch pathway comprises at least 14 gene products. Other, simpler terminal branches of the GSP are also used by gram-negative bacteria to secrete a more limited range of extracellular proteins...
  2. ncbi Type IV-like pili formed by the type II secreton: specificity, composition, bundling, polar localization, and surface presentation of peptides
    Guillaume Vignon
    Unité de Génétique Moléculaire CNRS URA 2172, Institut Pasteur, Paris, France
    J Bacteriol 185:3416-28. 2003
    ..Abnormally long pili that extend beyond the outer membrane are produced only when pilus length control and retraction are deregulated by overproduction of the major pseudopilus subunit (PulG)...
  3. ncbi Involvement of the twin-arginine translocation system in protein secretion via the type II pathway
    R Voulhoux
    Laboratoire d Ingenierie des Systemes Macromoleculaires, UPR9027, IBSM CNRS, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    EMBO J 20:6735-41. 2001
    ..Moreover, since P.aeruginosa phospholipases are secreted virulence factors, the Tat system appears to be a novel determinant of bacterial virulence...
  4. ncbi Biology of type II secretion
    M Sandkvist
    Department of Biochemistry, American Red Cross, Jerome H Holland Laboratory, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
    Mol Microbiol 40:271-83. 2001
    ..Different models for pilus-mediated secretion through the gated pore in the outer membrane are also presented, as are the possible properties that determine whether a protein is recognized and secreted by the type II pathway...
  5. ncbi An inner membrane platform in the type II secretion machinery of Gram-negative bacteria
    B Py
    Laboratoire de Chimie Bacterienne, IBSM, CNRS, 31 Chemin Joseph Aiguier, Marseille Cedex 20, 13402, France
    EMBO Rep 2:244-8. 2001
    ..We report that in Erwinia chrysanthemi, GspE (the putative NTPase), GspF, GspL and GspM constitute a complex in the inner membrane that is presumably used as a platform for assembling other ..
  6. ncbi Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion
    O Francetic
    Unité de Génétique moléculaire and Unité de Physicochimie de Macromolécules biologiques, Centre National de la Recherche scientifique URA1773, Institut Pasteur, 25 rue du Dr Roux, 75734 Paris, Cedex 15, France
    EMBO J 19:6697-703. 2000
    ..This is the first time that secretion of an endogenous extracellular protein has been demonstrated in E.coli K-12...
  7. ncbi Protein secretion in Escherichia coli K-12: dead or alive?
    A P Pugsley
    Unité de Génétique Moléculaire, CNRS URA 1773, Institut Pasteur, Paris, France
    Cell Mol Life Sci 54:347-52. 1998
    ....
  8. ncbi The cryptic general secretory pathway (gsp) operon of Escherichia coli K-12 encodes functional proteins
    O Francetic
    Unité de Génétique Moléculaire, Centre National de la Recherche Scientifique Unité de Recherche Associée 1149, Institut Pasteur, Paris, France
    J Bacteriol 178:3544-9. 1996
    ..Thus, the gsp operon of E. coli K-12 includes at least two functional genes which, together with the rest of the operon, are probably not expressed under laboratory conditions...
  9. ncbi The underlying mechanisms of type II protein secretion
    Alain Filloux
    Laboratoire d Ingenierie des Systemes Macromoleculaires, CNRS IBSM UPR9027, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    Biochim Biophys Acta 1694:163-79. 2004
    ....
  10. ncbi Multiple interactions between pullulanase secreton components involved in stabilization and cytoplasmic membrane association of PulE
    O M Possot
    Unité de Génétique Moléculaire, CNRS, URA 1773, Institut Pasteur, 75724 Paris, Cedex 15, France
    J Bacteriol 182:2142-52. 2000
    ....
  11. ncbi Two regions of EpsL involved in species-specific protein-protein interactions with EpsE and EpsM of the general secretion pathway in Vibrio cholerae
    M Sandkvist
    Department of Biochemistry, American Red Cross, Holland Laboratory, Rockville, Maryland 20855, USA sandkvis2usa redcross org
    J Bacteriol 182:742-8. 2000
    ..This site is present in the region between amino acids 216 and 296, which contains the predicted membrane-spanning segment of EpsL...