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Genomes and Genes | gadESummaryGene Symbol: gadE Description: DNA-binding transcriptional activator Alias: ECK3496, JW3480, yhiE, yhiT Species: Top Publications
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Publications
GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coliFlorence Hommais
Unité de Génétique des Génomes Bactériens, URA CNRS 2185, Institut Pasteur, France
Microbiology 150:61-72. 2004..Target genes of both YhiE (renamed GadE) and GadX were identified by a transcriptomic approach...- Mechanisms of transcription activation exerted by GadX and GadW at the gadA and gadBC gene promoters of the glutamate-based acid resistance system in Escherichia coliAngela Tramonti
Istituto di Biologia e Patologia Molecolari, CNR, Italy
J Bacteriol 188:8118-27. 2006.... - GadE (YhiE) activates glutamate decarboxylase-dependent acid resistance in Escherichia coli K-12Zhuo Ma
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, AL 36688, USA
Mol Microbiol 49:1309-20. 2003..We report that the LuxR-like regulator GadE (formerly YhiE) is required for expression of gadA and gadBC regardless of media or growth conditions... - Sodium regulates Escherichia coli acid resistance, and influences GadX- and GadW-dependent activation of gadEHope Richard
Department of Microbiology and Immunology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA
Microbiology 153:3154-61. 2007..The regulatory protein GadE is the essential activator of the gadA and gadBC genes... - Regulatory network of acid resistance genes in Escherichia coliNobuhisa Masuda
Department of Genetics, Warren Alpert Building, Room 513, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA
Mol Microbiol 48:699-712. 2003..This acid resistance is partially abolished by deletion of ydeP, yhiE or ydeO, genes induced by EvgA overexpression. Microarray analysis identified two classes of operons (genes)... - GadX/GadW-dependent regulation of the Escherichia coli acid fitness island: transcriptional control at the gadY-gadW divergent promoters and identification of four novel 42 bp GadX/GadW-specific binding sitesAngela Tramonti
Istituto di Biologia e Patologia Molecolari, CNR, Sapienza Universita di Roma, Roma, Italy
Mol Microbiol 70:965-82. 2008..KCTGATNTTTWYNTYAK-3', is also present in the regulatory region of the slp-yhiF, hdeAB and gadE-mtdEF operons, all of which belong to the AFI... - Gene expression profiling of the pH response in Escherichia coliDon L Tucker
Advanced Center for Genome Technology, The University of Oklahoma, Norman, Oklahoma 73069 0245, USA
J Bacteriol 184:6551-8. 2002..One of these putative regulators, yhiE, was shown to significantly increase acid resistance when overexpressed in cells that had not been preinduced by .. - Molecular mechanism of transcriptional cascade initiated by the EvgS/EvgA system in Escherichia coli K-12Junji Itou
Department of Bioscience, Graduate School of Agriculture, Kinki University, 3327 204 Nakamachi, Nara 631 8505, Japan
Biosci Biotechnol Biochem 73:870-8. 2009..system in Escherichia coli, followed by sequential induction of the transcriptional regulators, YdeO and GadE. Overexpression of EvgA, the response regulator of the EvgS/EvgA system, is known to induce the expression of a .. - Functional characterization and regulation of gadX, a gene encoding an AraC/XylS-like transcriptional activator of the Escherichia coli glutamic acid decarboxylase systemAngela Tramonti
Dipartimento di Scienze Biochimiche A Rossi Fanelli, Centro di Biologia Molecolare del Consiglio Nazionale delle Ricerche, Universita di Roma La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy
J Bacteriol 184:2603-13. 2002..Gel shift and DNase I footprinting analyses with a MalE-GadX fusion protein demonstrate that GadX binds gadA and gadBC promoters at different sites and with different binding affinities... - A 750 bp sensory integration region directs global control of the Escherichia coli GadE acid resistance regulatorAtef K Sayed
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, AL 36688, USA
Mol Microbiol 71:1435-50. 2009..coli survives pH 2 environments through an acid resistance (AR) system regulated by the transcriptional activator GadE. Numerous proteins control gadE at an upstream, conserved, 798 bp intergenic region... - The AraC-family regulator GadX enhances multidrug resistance in Escherichia coli by activating expression of mdtEF multidrug efflux genesKunihiko Nishino
Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, 8 1 Mihogaoka, Ibaraki, Osaka, Japan
J Infect Chemother 14:23-9. 2008..Our results indicate that the GadX regulator, in addition to its role in acid resistance, increases multidrug resistance in E. coli by activating the MdtEF multidrug efflux pump... - The Escherichia coli AraC-family regulators GadX and GadW activate gadE, the central activator of glutamate-dependent acid resistanceAtef K Sayed
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, AL 36688, USA
Microbiology 153:2584-92. 2007..Expression of the essential transcriptional activator of this system, GadE, is controlled by several regulators in a hierarchical fashion... - A role for Lon protease in the control of the acid resistance genes of Escherichia coliJohanna Heuveling
Institut für Biologie Mikrobiologie, Freie Universitat Berlin, 14195 Berlin, Germany
Mol Microbiol 69:534-47. 2008..Lon-affected genes also included the major acid resistance genes (gadA, gadBC, gadE, hdeAB and hdeD), which led to the discovery that the essential acid resistance regulator GadE (whose expression is .. - Indole is an inter-species biofilm signal mediated by SdiAJintae Lee
Artie McFerrin Department of Chemical Engineering, Texas A and M University, College Station, TX 77843 3122, USA
BMC Microbiol 7:42. 2007..g., astD, tnaB, gabT), multi-drug exporters, and the pathogenicity island of E. coli; however, its impact on biofilm formation has not been well-studied... - Acid stress response in Escherichia coli: mechanism of regulation of gadA transcription by RcsB and GadEMarie Pierre Castanié-Cornet
Universite de Toulouse, UPS, Laboratoire de Microbiologie et Genetique Moleculaires, F 31000 Toulouse and CNRS, LMGM, F 31000 Toulouse, France
Nucleic Acids Res 38:3546-54. 2010..The expression of the corresponding genes is controlled by GadE, the central activator of glutamate-dependent acid resistance (GDAR)... - N-acetyl-d-glucosamine induces the expression of multidrug exporter genes, mdtEF, via catabolite activation in Escherichia coliHidetada Hirakawa
Institute of Scientific and Industrial Research, Osaka University, 8 1 Mihogaoka, Ibaraki shi, Osaka 567 0047, Japan
J Bacteriol 188:5851-8. 2006..Other PTS sugars, glucose and d-glucosamine, also induced mdtEF gene expression. These results suggest that mdtEF expression is stimulated through catabolite control... - [Structure function relationship of the LysR type transcriptional regulator]Toshiya Senda
Tanpakushitsu Kakusan Koso 50:1535-40. 2005 - The Era-like GTPase TrmE conditionally activates gadE and glutamate-dependent acid resistance in Escherichia coliShimei Gong
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, AL 36688, USA
Mol Microbiol 54:948-61. 2004..TrmE controls GAD transcription by affecting the expression of GadE, the essential activator of the gadA and gadBC genes... - Characterization of EvgAS-YdeO-GadE branched regulatory circuit governing glutamate-dependent acid resistance in Escherichia coliZhuo Ma
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, AL 36688, USA
J Bacteriol 186:7378-89. 2004..A microarray study using overexpressed regulators uncovered evgAS and ydeO as potential regulators of gadE, now known to encode the essential activator of the gadA and gadBC genes... - Molecular biology of the LysR family of transcriptional regulatorsM A Schell
Department of Microbiology, University of Georgia, Athens 30602
Annu Rev Microbiol 47:597-626. 1993..Coinducer causes additional interactions of LTTRs with sequences near the -35 RNA polymerase binding site and/or DNA bending that results in transcription activation... - An activator of glutamate decarboxylase genes regulates the expression of enteropathogenic Escherichia coli virulence genes through control of the plasmid-encoded regulator, PerS Shin
Center for Vaccine Development and Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 W Baltimore St, Baltimore, MD 21201, USA
Mol Microbiol 41:1133-50. 2001.... - Collaborative regulation of Escherichia coli glutamate-dependent acid resistance by two AraC-like regulators, GadX and GadW (YhiW)Zhuo Ma
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile 36688, USA
J Bacteriol 184:7001-12. 2002..These complex control circuits impose tight rein over expression of the gadA and gadBC system yet provide flexibility for inducing acid resistance under many conditions that presage acid stress... - Anticipating an alkaline stress through the Tor phosphorelay system in Escherichia coliChristophe Bordi
Laboratoire de Chimie Bacterienne, Institut de Biologie Structurale et Microbiologie, Centre National de la Recherche Scientifique, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
Mol Microbiol 48:211-23. 2003..One unit, tnaLAB, is positively regulated whereas the other six, gadA, gadBC, hdeAB, hdeD, yhiE and yhiM, are negatively regulated by this system... - Stability and oligomerization of recombinant GadX, a transcriptional activator of the Escherichia coli glutamate decarboxylase systemA Tramonti
Dipartimento di Scienze Biochimiche A Rossi Fanelli and Instituto di Biologia e Patologia Moleculari del CNR, Universita degli Studi di Roma La Sapienza, PiazzaleAldo Moro 5, 00185 Rome, Italy
Biochim Biophys Acta 1647:376-80. 2003..This experimental evidence is in line with the well-known tendency of AraC/XylS-like proteins to dimerize via their N-terminal domain... - Increased adherence to Caco-2 cells caused by disruption of the yhiE and yhiF genes in enterohemorrhagic Escherichia coli O157:H7Ichiro Tatsuno
Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato ku, Tokyo 108 8639, Japan
Infect Immun 71:2598-606. 2003..another possessed the insertion within the yhiF gene, and the remaining six mutants had their insertions in the yhiE gene... - Genes of the GadX-GadW regulon in Escherichia coliDon L Tucker
Advanced Center for Genome Technology, The University of Oklahoma, Norman, Oklahoma 73019, USA
J Bacteriol 185:3190-201. 2003..Thus, E. coli colonization of the mouse does not appear to require glutamate-dependent acid resistance... - Acid resistance in Escherichia coliHope T Richard
Department of Microbiology and Immunology, College of Medicine, University of South Alabama Mobile, Alabama 36688, USA
Adv Appl Microbiol 52:167-86. 2003..5. They also protect against acid stress involved in food processing and facilitate the low infectious dose characteristic of E. coli, significantly contributing to the pathogenesis of this organism... - The curli biosynthesis regulator CsgD co-ordinates the expression of both positive and negative determinants for biofilm formation in Escherichia coliEva Brombacher
Swiss Federal Institute of Environmental Technology EAWAG, Uberlandstrasse 133, CH 8600 Dubendorf, Switzerland
Microbiology 149:2847-57. 2003..coli by contemporary activation of adhesion positive determinants (the curli-encoding csg operons and the product of the yaiC gene) and repression of negative effectors such as yagS and pepD... - pH-Dependent modulation of cyclic AMP levels and GadW-dependent repression of RpoS affect synthesis of the GadX regulator and Escherichia coli acid resistanceZhuo Ma
Department of Microbiology and Immunology, University of South Alabama College of Medicine, Mobile, Alabama 36688, USA
J Bacteriol 185:6852-9. 2003..We recently demonstrated that GadE, the essential activator of the genes, was itself acid induced... - Physical map location of a set of Escherichia coli genes (hde) whose expression is affected by the nucleoid protein H-NST Yoshida
Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Japan
J Bacteriol 175:7747-8. 1993 - RcsB is required for inducible acid resistance in Escherichia coli and acts at gadE-dependent and -independent promotersMatthew D Johnson
School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
J Bacteriol 193:3653-6. 2011RcsB interacts with GadE to mediate acid resistance in stationary-phase Escherichia coli K-12... - Escherichia coli gene expression responsive to levels of the response regulator EvgANobuhisa Masuda
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
J Bacteriol 184:6225-34. 2002..This acid resistance was abolished by deletion of ydeP, ydeO, or yhiE, which was induced by EvgA overexpression...