wisp

Summary

Gene Symbol: wisp
Description: wispy
Alias: CG15737, DmCG15737, Dmel\CG15737, TAMP, Wisp, fs(1)M19, CG15737-PA, female sterile(1)M19, temprano, toll pathway activation mediating protein, wisp-PA
Species: fruit fly

Top Publications

  1. pmc subito encodes a kinesin-like protein required for meiotic spindle pole formation in Drosophila melanogaster
    Kelly L Giunta
    Waksman Institute and Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA
    Genetics 160:1489-501. 2002
  2. doi PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila
    Perrine Benoit
    mRNA Regulation and Development, Institut de Genetique Humaine, CNRS UPR 1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France
    Development 135:1969-79. 2008
  3. pmc Wispy, the Drosophila homolog of GLD-2, is required during oogenesis and egg activation
    Jun Cui
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Genetics 178:2017-29. 2008
  4. pmc The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity
    Li Chin Wong
    Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
    PLoS ONE 6:e24355. 2011
  5. pmc Genome-wide analysis of mRNA decay patterns during early Drosophila development
    Stefan Thomsen
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Genome Biol 11:R93. 2010
  6. pmc The Drosophila melanogaster seminal fluid protease "seminase" regulates proteolytic and post-mating reproductive processes
    Brooke A LaFlamme
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
    PLoS Genet 8:e1002435. 2012
  7. ncbi A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans
    Liaoteng Wang
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Nature 419:312-6. 2002
  8. pmc The Drosophila wispy gene is required for RNA localization and other microtubule-based events of meiosis and early embryogenesis
    A E Brent
    Department of Biological Sciences, Columbia University, New York, New York 10027, USA
    Genetics 154:1649-62. 2000
  9. pmc Developmental genetics of the Drosophila egg. I. Identification of 59 sex-linked cistrons with maternal effects on embryonic development
    J D Mohler
    Genetics 85:259-72. 1977
  10. pmc Regulation of maternal transcript destabilization during egg activation in Drosophila
    Wael Tadros
    Program in Developmental Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Genetics 164:989-1001. 2003

Scientific Experts

  • Stefan Thomsen
  • Brooke A LaFlamme
  • Li Chin Wong
  • Mariana F Wolfner
  • Jun Cui
  • Perrine Benoit
  • Marvin Wickens
  • Wael Tadros
  • Kelly L Giunta
  • Liaoteng Wang
  • K Ravi Ram
  • John Yates
  • Paul Schedl
  • Ian McLeod
  • Ali Sarkeshik
  • Alexandre Costa
  • Saw Kyin
  • David Perlman
  • A E Brent
  • Catherine Papin
  • Vanessa L Horner
  • Kritika E Kumar
  • Katharine L Sackton
  • Jae Eun Kwak
  • Martine Simonelig
  • Jennifer L Semotok
  • Howard D Lipshitz
  • Arash Bashirullah
  • Bruce H Reed
  • Ramona L Cooperstock
  • Simon A Houston
  • Elizabeth A Manheim
  • Lisa C Kadyk
  • Christian R Eckmann
  • Janet K Jang
  • Judith Kimble
  • Kim S McKim
  • Gayathri Subramanian
  • A MacQueen
  • T Hazelrigg
  • J D Mohler

Detail Information

Publications10

  1. pmc subito encodes a kinesin-like protein required for meiotic spindle pole formation in Drosophila melanogaster
    Kelly L Giunta
    Waksman Institute and Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA
    Genetics 160:1489-501. 2002
    ..sub is also required for the early embryonic divisions but is otherwise dispensable for most mitotic divisions...
  2. doi PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila
    Perrine Benoit
    mRNA Regulation and Development, Institut de Genetique Humaine, CNRS UPR 1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France
    Development 135:1969-79. 2008
    ..We conclude that two distinct poly(A) polymerases have a role in cytoplasmic polyadenylation in the female germline, each of them being specifically required for different steps of oogenesis...
  3. pmc Wispy, the Drosophila homolog of GLD-2, is required during oogenesis and egg activation
    Jun Cui
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Genetics 178:2017-29. 2008
    ..wispy (wisp) maternal-effect mutations in Drosophila block development during the egg-to-embryo transition...
  4. pmc The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity
    Li Chin Wong
    Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
    PLoS ONE 6:e24355. 2011
    ..isoforms are in slowly sedimenting complexes that contain the translational repressor Bruno, while the hyperphosphorylated isoforms assemble into large complexes that co-sediment with polysomes and contain the Wisp poly(A) polymerase.
  5. pmc Genome-wide analysis of mRNA decay patterns during early Drosophila development
    Stefan Thomsen
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Genome Biol 11:R93. 2010
    ....
  6. pmc The Drosophila melanogaster seminal fluid protease "seminase" regulates proteolytic and post-mating reproductive processes
    Brooke A LaFlamme
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA
    PLoS Genet 8:e1002435. 2012
    ..These results point to an important role for proteolysis among insect SFPs and suggest that protease cascades may be a mechanism for precise temporal regulation of multiple post-mating responses in females...
  7. ncbi A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans
    Liaoteng Wang
    Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Nature 419:312-6. 2002
    ..We suggest that GLD-2 is the prototype for a class of regulatory cytoplasmic PAPs that are recruited to specific mRNAs by a binding partner, thereby targeting those mRNAs for polyadenylation and increased expression...
  8. pmc The Drosophila wispy gene is required for RNA localization and other microtubule-based events of meiosis and early embryogenesis
    A E Brent
    Department of Biological Sciences, Columbia University, New York, New York 10027, USA
    Genetics 154:1649-62. 2000
    ..We propose that the wispy gene product functions directly in several microtubule-based events in meiosis and early embryogenesis and speculate about its possible mode of action...
  9. pmc Developmental genetics of the Drosophila egg. I. Identification of 59 sex-linked cistrons with maternal effects on embryonic development
    J D Mohler
    Genetics 85:259-72. 1977
    ..The mutant strains are potentially important material for the study of developing egg envelopes and for furthering the analysis of causation in embryogenesis and its origins in oogenesis...
  10. pmc Regulation of maternal transcript destabilization during egg activation in Drosophila
    Wael Tadros
    Program in Developmental Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    Genetics 164:989-1001. 2003
    ....