Gene Symbol: VhaAC45
Description: Vacuolar H[+] ATPase AC45 accessory subunit
Alias: CG8029, Dmel\CG8029, anon-WO0118547.117, l(2)SH1634, l(2)SH2 1634, vhaAC45, vacuolar H[+] ATPase AC45 accessory subunit, CG8029-PA, CG8029-PB, VhaAC45-PA, VhaAC45-PB, lethal (2) SH1634, vacuolar H[+] ATPase accessory protein AC45
Species: fruit fly

Top Publications

  1. Tognon E, Kobia F, Busi I, Fumagalli A, De Masi F, Vaccari T. Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster. Autophagy. 2016;12:499-514 pubmed publisher
    ..Our data suggest that lysosomal-associated functions regulated by the TFEB-V-ATPase axis might play a conserved role in shaping cell fate. ..
  2. Adamson A, Chohan K, Swenson J, Lajeunesse D. A Drosophila model for genetic analysis of influenza viral/host interactions. Genetics. 2011;189:495-506 pubmed publisher
  3. Mauvezin C, Nagy P, Juhász G, Neufeld T. Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification. Nat Commun. 2015;6:7007 pubmed publisher
    ..Collectively, our results indicate that lysosomal acidification is not a prerequisite for fusion, and that BafilomycinA1 inhibits fusion independent of its effect on lysosomal pH. ..