Gene Symbol: Tpl94D
Description: Transition protein-like 94D
Alias: CG31281, Dmel\CG31281, NEST:bs11b10, NEST:bs30g09, Tpl[94D], tpl, tpl94D, tpl[94D], transition protein-like 94D, CG31281-PA, CG31281-PB, Tpl94D-PA, Tpl94D-PB, transition protein-like[94D]
Species: fruit fly
Rathke C, Barckmann B, Burkhard S, Jayaramaiah Raja S, Roote J, Renkawitz Pohl R. Distinct functions of Mst77F and protamines in nuclear shaping and chromatin condensation during Drosophila spermiogenesis. Eur J Cell Biol. 2010;89:326-38 pubmed publisher
..Moreover, we show that in prot Delta mutants, histone degradation, distribution of DNA breaks and Tpl(94D)-eGFP and Mst77F expression proceed as in wild-type males...
Matsuno M, Horiuchi J, Tully T, Saitoe M. The Drosophila cell adhesion molecule klingon is required for long-term memory formation and is regulated by Notch. Proc Natl Acad Sci U S A. 2009;106:310-5 pubmed publisher
..Furthermore, Notch-induced enhancement of LTM is disrupted by a klg mutation. We propose that Klg is a downstream effector of Notch signaling that links Notch activity to memory. ..
Awe S, Renkawitz Pohl R. Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster. Syst Biol Reprod Med. 2010;56:44-61 pubmed publisher
..Thus, we conclude that H4 hyperacetylation is an essential feature but not the sole inducer of the histone to protamine switch during spermiogenesis. ..
Sartain C, Cui J, Meisel R, Wolfner M. The poly(A) polymerase GLD2 is required for spermatogenesis in Drosophila melanogaster. Development. 2011;138:1619-29 pubmed publisher
..Our results indicate that GLD2 is an important regulator of late spermatogenesis and is the first example of a Gld-2 family member that plays a significant role specifically in male gametogenesis. ..
Kimura S. The Nap family proteins, CG5017/Hanabi and Nap1, are essential for Drosophila spermiogenesis. FEBS Lett. 2013;587:922-9 pubmed publisher
..These findings imply that Nap family proteins might individually sustain cytoskeleton-based morphogenesis, rather than histone biogenesis. ..
Tirmarche S, Kimura S, Sapey Triomphe L, Sullivan W, Landmann F, Loppin B. Drosophila protamine-like Mst35Ba and Mst35Bb are required for proper sperm nuclear morphology but are dispensable for male fertility. G3 (Bethesda). 2014;4:2241-5 pubmed publisher
..Here, we have precisely deleted the Mst35B locus by homologous recombination, and we confirm the dispensability of Mst35Ba/b for fertility. ..
GÃ¤rtner S, Rothenbusch S, Buxa M, Theofel I, Renkawitz R, Rathke C, et al
. The HMG-box-containing proteins tHMG-1 and tHMG-2 interact during the histone-to-protamine transition in Drosophila spermatogenesis. Eur J Cell Biol. 2015;94:46-59 pubmed publisher
..In Drosophila, the transition-protein-like protein Tpl94D contains an HMG-box domain and is expressed during chromatin reorganization...
Alvi Z, Chu T, Schawaroch V, Klaus A. Genomic and expression analysis of transition proteins in Drosophila. Spermatogenesis. 2015;5:e1178518 pubmed publisher
..protein-like proteins in 12 Drosophila species based on the reference sequences of transition protein-like protein (Tpl (94D) ) expressed in Drosophila melanogaster sperm nuclei...