tbrd-1

Summary

Gene Symbol: tbrd-1
Description: testis-specifically expressed bromodomain containing protein-1
Alias: CG13597, Dmel\CG13597, tBRD-1, testis-specifically expressed bromodomain containing protein-1, CG13597-PA, tbrd-1-PA
Species: fruit fly

Top Publications

  1. Leser K, Awe S, Barckmann B, Renkawitz Pohl R, Rathke C. The bromodomain-containing protein tBRD-1 is specifically expressed in spermatocytes and is essential for male fertility. Biol Open. 2012;1:597-606 pubmed publisher
    ..By inhibitor treatment of cultured testis we observed that sub-cellular localisation of tBRD-1 may depend on the acetylation status of primary spermatocytes. ..
  2. Theofel I, Bartkuhn M, Hundertmark T, Boettger T, Gärtner S, Leser K, et al. tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family. PLoS ONE. 2014;9:e108267 pubmed publisher
  3. Kimura S, Loppin B. Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes. Open Biol. 2015;5:140145 pubmed publisher
    ..We propose that Drosophila tBRD-1 and tBRD-2 associate into a functional BET complex in spermatocytes, which recapitulates the activity of the single mammalian BRDT-like protein. ..

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