Mst1

Summary

Gene Symbol: Mst1
Description: macrophage stimulating 1
Alias: E2F2, D8h3f15s2, E2F transcription factor 2, Macrophage stimulating 1 (hepatocyte growth factor-like), hepatocyte growth factor-like protein
Species: rat

Top Publications

  1. pmc Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis
    Bei You
    Institute of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China
    PLoS ONE 8:e58697. 2013
  2. ncbi Molecular cloning of rat macrophage-stimulating protein and its involvement in the male reproductive system
    K Ohshiro
    Department of Cell Differentition, Kumamoto University School of Medicine, Japan
    Biochem Biophys Res Commun 227:273-80. 1996
  3. ncbi Critical role of Mst1 in vascular remodeling after injury
    Hiroki Ono
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, 812 8582 Fukuoka, Japan
    Arterioscler Thromb Vasc Biol 25:1871-6. 2005
  4. ncbi Making omelets without breaking eggs: E2F-mediated induction of cardiomyoycte cell proliferation without stimulation of apoptosis
    Henning Ebelt
    Department of Medicine III, Martin Luther University, Halle, Germany
    Cell Cycle 5:2436-9. 2006
  5. ncbi Neutralization of macrophage-stimulating protein ameliorates renal injury in anti-thy 1 glomerulonephritis
    Teresa Rampino
    Unit of Nephrology, Dialysis and Transplantation, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo and University of Pavia, Pavia, Italy
    J Am Soc Nephrol 18:1486-96. 2007
  6. pmc Regulation of neuronal cell death by MST1-FOXO1 signaling
    Zengqiang Yuan
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 284:11285-92. 2009
  7. pmc Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling
    Hee Jae Yun
    School of Life Sciences and Biotechnology, Korea University, Seoul, Korea
    EMBO J 30:2465-76. 2011

Scientific Experts

  • Teresa Rampino
  • Bei You
  • Hee Jae Yun
  • Zengqiang Yuan
  • Henning Ebelt
  • Hiroki Ono
  • Qing Qin
  • Jianxin Sun
  • Bing Yi
  • Zhiyun Xu
  • Shengdong Huang
  • Yang Yuan
  • Kyoung Wan Yoon
  • Eui Ju Choi
  • Jae Keun Lee
  • Gerd G Maul
  • Dae Sik Lim
  • Je Hyun Yoon
  • Hyun Jung Oh
  • Eun Hee Kim
  • Kyung Tae Noh
  • Ji Soo Chae
  • Sang Phil Oh
  • Sang Gil Hwang
  • Steven Gygi
  • Judit Villen
  • Azad Bonni
  • Maria K Lehtinen
  • Paola Merlo
  • Thomas Braun
  • Karl Werdan
  • Ursula Muller-Werdan
  • Zhipei Liu
  • Yasuko Hashiguchi
  • Kenji Sunagawa
  • Toshihiro Ichiki
  • Kae Fukuyama
  • Ikuyo Imayama
  • Junichi Sadoshima
  • Hideki Ohtsubo
  • K Ohshiro
  • N Takasu
  • K Matsuno
  • O Sakamoto
  • T Ezaki
  • I Hamaguchi
  • T Suda
  • A Iwama

Detail Information

Publications7

  1. pmc Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosis
    Bei You
    Institute of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China
    PLoS ONE 8:e58697. 2013
    Mammalian sterile 20-like kinase 1 (Mst1) is a critical component of the Hippo signaling pathway, which regulates a variety of biological processes ranging from cell contact inhibition, organ size control, apoptosis and tumor suppression ..
  2. ncbi Molecular cloning of rat macrophage-stimulating protein and its involvement in the male reproductive system
    K Ohshiro
    Department of Cell Differentition, Kumamoto University School of Medicine, Japan
    Biochem Biophys Res Commun 227:273-80. 1996
    ..Our findings reveal new possible roles of the MSP-STK/RON signaling pathway...
  3. ncbi Critical role of Mst1 in vascular remodeling after injury
    Hiroki Ono
    Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, 812 8582 Fukuoka, Japan
    Arterioscler Thromb Vasc Biol 25:1871-6. 2005
    ..b>Mst1 is a ubiquitously expressed serine/threonine kinase known to be activated in response to a wide variety of ..
  4. ncbi Making omelets without breaking eggs: E2F-mediated induction of cardiomyoycte cell proliferation without stimulation of apoptosis
    Henning Ebelt
    Department of Medicine III, Martin Luther University, Halle, Germany
    Cell Cycle 5:2436-9. 2006
    ..According to a widely accepted model, E2F1, E2F2, and E2F3 are classified as "activating" E2Fs since they induce proliferation of quiescent cells whereas E2F4 and ..
  5. ncbi Neutralization of macrophage-stimulating protein ameliorates renal injury in anti-thy 1 glomerulonephritis
    Teresa Rampino
    Unit of Nephrology, Dialysis and Transplantation, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo and University of Pavia, Pavia, Italy
    J Am Soc Nephrol 18:1486-96. 2007
    ..LPS-stimulated monocytes were attracted by MSP. These results demonstrate a pathogenic role of the MSP/RON system in anti-Thy 1 nephritis...
  6. pmc Regulation of neuronal cell death by MST1-FOXO1 signaling
    Zengqiang Yuan
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 284:11285-92. 2009
    The protein kinase mammalian Sterile 20-like kinase 1 (MST1) plays a critical role in the regulation of cell death...
  7. pmc Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling
    Hee Jae Yun
    School of Life Sciences and Biotechnology, Korea University, Seoul, Korea
    EMBO J 30:2465-76. 2011
    ..Here, we show that Daxx and mammalian Ste20-like kinase-1 (MST1) mediate apoptosis elicited by interferon-γ (IFN-γ) in microglia...