Syx4

Summary

Gene Symbol: Syx4
Description: Syntaxin 4
Alias: CG2715, Dm Syx4, DmSyx4, Dmel\CG2715, EG:95B7.1, EG:95B7.11, Syx, Syx-4, syx4, syntaxin 4, CG2715-PA, CG2715-PB, Syx4-PA, Syx4-PB, syntaxin
Species: fruit fly
Products:     Syx4

Top Publications

  1. Lagow R, Bao H, Cohen E, Daniels R, Zuzek A, Williams W, et al. Modification of a hydrophobic layer by a point mutation in syntaxin 1A regulates the rate of synaptic vesicle fusion. PLoS Biol. 2007;5:e72 pubmed
    ..Using the Drosophila neuromuscular synapse as a model, we show that a mutation modifying a hydrophobic layer in syntaxin 1A regulates the rate of vesicle fusion...
  2. Dumstrei K, Wang F, Hartenstein V. Role of DE-cadherin in neuroblast proliferation, neural morphogenesis, and axon tract formation in Drosophila larval brain development. J Neurosci. 2003;23:3325-35 pubmed
    ..We conclude that DE-cadherin plays a pivotal role in larval brain proliferation, brain cortex morphogenesis, and axon growth. ..
  3. Wagh D, Rasse T, Asan E, Hofbauer A, Schwenkert I, Dürrbeck H, et al. Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila. Neuron. 2006;49:833-44 pubmed
    ..We propose that BRP is critical for intact AZ structure and normal-evoked neurotransmitter release at chemical synapses of Drosophila. ..
  4. Farkaš R, Beňová Liszeková D, Mentelová L, Mahmood S, Ďatková Z, Beňo M, et al. Vacuole dynamics in the salivary glands of Drosophila melanogaster during prepupal development. Dev Growth Differ. 2015;57:74-96 pubmed publisher
    ..and genetic tools, including mutations or transgenes for shi, Rab5, Rab11, vha55, vha68-2, vha36-1, syx1A, syx4, and Vps35 to characterize the dramatic series of cellular changes occurring in the SG cells between pupariation ..
  5. Morelli E, Ginefra P, Mastrodonato V, Beznoussenko G, Rusten T, Bilder D, et al. Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila. Autophagy. 2014;10:2251-68 pubmed publisher
  6. Harris K, Zhang Y, Piccioli Z, Perrimon N, Littleton J. The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. elife. 2016;5: pubmed publisher
    ..Here we characterize one candidate, the postsynaptic t-SNARE Syntaxin 4 (Syx4)...
  7. Harr B, Kauer M, Schl tterer C. Hitchhiking mapping: a population-based fine-mapping strategy for adaptive mutations in Drosophilamelanogaster. Proc Natl Acad Sci U S A. 2002;99:12949-54 pubmed publisher
    ..Our study suggests that hitchhiking mapping is a universal approach for the identification of ecologically important mutations...
  8. Pereanu W, Shy D, Hartenstein V. Morphogenesis and proliferation of the larval brain glia in Drosophila. Dev Biol. 2005;283:191-203 pubmed
    ..This increase results from mitosis of differentiated glia, but, more significantly, from the proliferation of neuroblasts. ..
  9. Gangar A, Rossi G, Andreeva A, Hales R, Brennwald P. Structurally conserved interaction of Lgl family with SNAREs is critical to their cellular function. Curr Biol. 2005;15:1136-42 pubmed
    ..These data support the model that the Lgl family functions in cell polarity, at least in part, by regulating SNARE-mediated membrane delivery events at the cell surface. ..

More Information

Publications11

  1. Pereanu W, Hartenstein V. Neural lineages of the Drosophila brain: a three-dimensional digital atlas of the pattern of lineage location and projection at the late larval stage. J Neurosci. 2006;26:5534-53 pubmed
    ..Third, the atlas can serve as a repository for genes expressed in lineage-specific patterns. ..
  2. Demakova O, Pokholkova G, Kolesnikova T, Demakov S, Andreyeva E, Belyaeva E, et al. The SU(VAR)3-9/HP1 complex differentially regulates the compaction state and degree of underreplication of X chromosome pericentric heterochromatin in Drosophila melanogaster. Genetics. 2007;175:609-20 pubmed
    ..So, we show that pericentric heterochromatin is heterogeneous in its requirement for SU(VAR)3-9 with respect to the establishment of the condensed state, time of replication, and DNA polytenization. ..