Gene Symbol: starvin
Description: starvin
Alias: CG10745, CG14108, CG32130, Dmel\CG32130, GH04349, Stv, cg32130, l(3)00543, starvin, CG32130-PA, CG32130-PB, CG32130-PC, CG32130-PD, CG32130-PE, CG32130-PF, CG32130-PG, Dm-Starvin, lethal (3) 00543, starving, stv-PA, stv-PB, stv-PC, stv-PD, stv-PE, stv-PF, stv-PG
Species: fruit fly

Top Publications

  1. Arndt V, Dick N, Tawo R, Dreiseidler M, Wenzel D, Hesse M, et al. Chaperone-assisted selective autophagy is essential for muscle maintenance. Curr Biol. 2010;20:143-8 pubmed publisher
    ..Based on the characterization of the Drosophila melanogaster cochaperone Starvin (Stv), we define a conserved chaperone machinery required for Z disk maintenance...
  2. Coulson M, Robert S, Saint R. Drosophila starvin encodes a tissue-specific BAG-domain protein required for larval food uptake. Genetics. 2005;171:1799-812 pubmed
    ..We show that the gene, termed starvin (stv), is expressed in a highly tissue-specific manner, accumulating primarily in tendon cells following germ-..
  3. Carra S, Boncoraglio A, Kanon B, Brunsting J, Minoia M, Rana A, et al. Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases. J Biol Chem. 2010;285:37811-22 pubmed publisher
    ..Our current data further support the link between the HSPB8-BAG3 complex, autophagy, and folding diseases and demonstrate that impairment or loss of function of HSPB8 might accelerate the progression and/or severity of folding diseases. ..
  4. Colinet H, Siaussat D, Bozzolan F, Bowler K. Rapid decline of cold tolerance at young age is associated with expression of stress genes in Drosophila melanogaster. J Exp Biol. 2013;216:253-9 pubmed publisher
    ..whether expression (basal and induced) of eight stress genes (hsp22, hsp23, hsp40, hsp68, hsp70Aa, hsp83, Starvin and Frost) varied post-eclosion in correspondence with changes found in cold tolerance...
  5. Demontis F, Piccirillo R, Goldberg A, Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Dis Model Mech. 2013;6:1339-52 pubmed publisher
  6. Jensen L, Nielsen M, Loeschcke V. New candidate genes for heat resistance in Drosophila melanogaster are regulated by HSF. Cell Stress Chaperones. 2008;13:177-82 pubmed publisher
    ..The high induction in response to heat, which mimics the expression profile of Hsps, implies a role in the cellular heat response of these genes as well. ..
  7. Zhang Y, Arnosti D. Conserved catalytic and C-terminal regulatory domains of the C-terminal binding protein corepressor fine-tune the transcriptional response in development. Mol Cell Biol. 2011;31:375-84 pubmed publisher
    ..Our results indicate that the structural and enzymatic features of CtBP, previously thought to be dispensable for overall transcriptional control, are critical for modulating this protein's activity in diverse developmental settings. ..
  8. Colinet H, Hoffmann A. Gene and protein expression of Drosophila Starvin during cold stress and recovery from chill coma. Insect Biochem Mol Biol. 2010;40:425-8 pubmed publisher
    In Drosophila melanogaster, the sole member of the Bcl-2-associated anthanogene (BAG)-family proteins, called Starvin (Stv), has only been recently described...
  9. Gonsalves S, Moses A, Razak Z, Robert F, Westwood J. Whole-genome analysis reveals that active heat shock factor binding sites are mostly associated with non-heat shock genes in Drosophila melanogaster. PLoS ONE. 2011;6:e15934 pubmed publisher
    ..These results suggest that Drosophila HSF may be regulating many genes besides the known HS genes and that some of these genes may be regulated during non-stress conditions. ..

More Information


  1. Telonis Scott M, Clemson A, Johnson T, Sgrò C. Spatial analysis of gene regulation reveals new insights into the molecular basis of upper thermal limits. Mol Ecol. 2014;23:6135-51 pubmed publisher
    ..We focus on starvin (stv), recently identified as an important thermally responsive gene...
  2. Štětina T, Koštál V, Korbelová J. The Role of Inducible Hsp70, and Other Heat Shock Proteins, in Adaptive Complex of Cold Tolerance of the Fruit Fly (Drosophila melanogaster). PLoS ONE. 2015;10:e0128976 pubmed publisher
    ..Genetic elimination of Hsp70 up-regulation response has no effect on survival of chronic exposures to 0°C or mild acute cold shocks, while it negatively affects survival after severe acute cold shocks at temperatures below -8°C. ..