sta

Summary

Gene Symbol: sta
Description: stubarista
Alias: 37LRP/p40, CG14792, Dmel\CG14792, EG:80H7.6, Lam-r, P40, Rp 40, Rp40, RpSA, STA, Sta, anon-EST:Liang-2.56, chrX:1339078..1339216, clone 2.56, k14, l(1)2Af, l(1)G0130, l(1)G0448, stubarista, CG14792-PA, CG14792-PB, CG14792-PE, CG14792-PF, Laminin-receptor, laminin receptor, ribosomal protein SA, sta-PA, sta-PB, sta-PE, sta-PF
Species: fruit fly

Top Publications

  1. Melnick M, Noll E, Perrimon N. The Drosophila stubarista phenotype is associated with a dosage effect of the putative ribosome-associated protein D-p40 on spineless. Genetics. 1993;135:553-64 pubmed
    We describe the molecular characterization of the Drosophila melanogaster gene stubarista (sta) that encodes the highly conserved putative ribosome-associated protein D-p40...
  2. Prudhommeau C, Proust J. I-R hybrid dysgenesis in Drosophila melanogaster: nature and site specificity of induced recessive lethals. Mutat Res. 1990;230:135-57 pubmed
    ..These mutations probably occur during the transposition of I elements, hence their importance from an evolutionary standpoint. ..
  3. Marhold J, Zbylut M, Lankenau D, Li M, Gerlich D, Ballestar E, et al. Stage-specific chromosomal association of Drosophila dMBD2/3 during genome activation. Chromosoma. 2002;111:13-21 pubmed
    ..Our results indicate that dMBD2/3 forms specialized nuclear compartments to keep certain genes epigenetically silenced during genome activation. ..
  4. Jafar Nejad H, Acar M, Nolo R, Lacin H, Pan H, Parkhurst S, et al. Senseless acts as a binary switch during sensory organ precursor selection. Genes Dev. 2003;17:2966-78 pubmed
    ..In the presumptive SOPs that express high levels of Sens, it acts as a transcriptional activator and synergizes with proneural proteins. We therefore propose that Sens acts as a binary switch that is fundamental to SOP selection...
  5. Martin M, Ahern Djamali S, Hoffmann F, Saxton W. Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1. Mol Biol Cell. 2005;16:4225-30 pubmed
    ..A concomitant reduction in ena dosage rescued those defects. These results suggest that Ena/VASP, when not inhibited by the Abl pathway, can bind Khc and reduce its transport activity in axons. ..
  6. Morgan L. Effects of a Compound Duplication of the X Chromosome of Drosophila Melanogaster. Genetics. 1938;23:423-62 pubmed
  7. Simin K, Scuderi A, Reamey J, Dunn D, Weiss R, Metherall J, et al. Profiling patterned transcripts in Drosophila embryos. Genome Res. 2002;12:1040-7 pubmed
  8. Bielinski V, Mumby M. Functional analysis of the PP2A subfamily of protein phosphatases in regulating Drosophila S6 kinase. Exp Cell Res. 2007;313:3117-26 pubmed
    ..These results indicate that PP2A, but not other members of this subfamily, is likely to be a major S6K phosphatase in intact cells and is consistent with an important role for this phosphatase in the TOR pathway. ..
  9. Parry T, Theisen J, Hsu J, Wang Y, Corcoran D, Eustice M, et al. The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery. Genes Dev. 2010;24:2013-8 pubmed publisher
    ..Thus, the TCT motif is a novel transcriptional element that is distinct from the Inr. These findings reveal a specialized TCT-based transcription system that is directed toward the synthesis of ribosomal proteins. ..

More Information

Publications18

  1. Mazina O, Beliaeva E, Grafodatskaia V, Zhimulev I. [The effect of locus ecs in Drosophila melanogaster on fertility of females]. Genetika. 1990;26:1038-45 pubmed
    ..Sterile were all fully viable compounds carrying any of these mutations and rearrangements Df (1) sta, T(1; 3)sta, Df(1)St490, previously localized on the molecular map distally to the ecs locus...
  2. Pokholkova G, Makunin I, Belyaeva E, Zhimulev I. Observations on the induction of position effect variegation of euchromatic genes in Drosophila melanogaster. Genetics. 1993;134:231-42 pubmed
    ..Thus, a 20-kb heterochromatic sequence does not inactivate euchromatin joined to it. ..
  3. Regnard C, Straub T, Mitterweger A, Dahlsveen I, Fabian V, Becker P. Global analysis of the relationship between JIL-1 kinase and transcription. PLoS Genet. 2011;7:e1001327 pubmed publisher
    ..We hypothesise that one specific role of JIL-1 may be to reinforce, rather than to establish, the status of active chromatin through the phosphorylation of histone H3 at serine 10. ..
  4. Nakahara K, Kim K, Sciulli C, Dowd S, Minden J, Carthew R. Targets of microRNA regulation in the Drosophila oocyte proteome. Proc Natl Acad Sci U S A. 2005;102:12023-8 pubmed
    ..The preponderance of genes that control global protein abundance suggests this process is under tight control by miRNAs at the onset of fertilization. ..
  5. Gailite I, Egger Adam D, Wodarz A. The phosphoinositide-associated protein Rush hour regulates endosomal trafficking in Drosophila. Mol Biol Cell. 2012;23:433-47 pubmed publisher
    ..These results indicate that Rush controls trafficking from early to late endosomes and from late endosomes to lysosomes by modulating the activity of Rab proteins. ..
  6. Proust J, Prudhommeau C, Ladeveze V, Gotteland M, Fontyne Branchard M. I-R hybrid dysgenesis in Drosophila melanogaster. Use of in situ hybridization to show the association of I factor DNA with induced sex-linked recessive lethals. Mutat Res. 1992;268:265-85 pubmed
    ..Two rearrangement formation mechanisms are envisaged: crossing-over and 'target' exchanges. ..
  7. Creagh E, Brumatti G, Sheridan C, Duriez P, Taylor R, Cullen S, et al. Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival. PLoS ONE. 2009;4:e5055 pubmed publisher
    ..These data suggest that bicaudal/betaNAC is essential for cell survival and is a conserved target of caspases from flies to man. ..
  8. Torok I, Herrmann Horle D, Kiss I, Tick G, Speer G, Schmitt R, et al. Down-regulation of RpS21, a putative translation initiation factor interacting with P40, produces viable minute imagos and larval lethality with overgrown hematopoietic organs and imaginal discs. Mol Cell Biol. 1999;19:2308-21 pubmed
    ..RpS21 can interact strongly with P40, a ribosomal peripheral protein encoded by the stubarista (sta) gene...
  9. Mazina O, Belyaeva E, Zhimulev I. Cytogenetical analysis of the 2B3-4-2B11 region of the X chromosome of Drosophila melanogaster. VII. Influence of the ecs locus on female fertility. Mol Gen Genet. 1991;225:99-105 pubmed
    ..Viable heterozygotes carrying any of these mutations and the rearrangements Df(1)sta, T(1;3)sta, Df(1)St490, previously localized distal to the ecs locus, were also sterile...