Gene Symbol: Sox15
Description: Sox box protein 15
Alias: CG13945, CG8404, DSox-15, Dmel\CG8404, Dsox-15, SOX15, SOX50E, SOXF, Sox F, Sox50E, SoxE, SoxF, Sox box protein 15, CG8404-PA, Sox15-PA
Species: fruit fly
Miller S, Avidor Reiss T, Polyanovsky A, Posakony J. Complex interplay of three transcription factors in controlling the tormogen differentiation program of Drosophila mechanoreceptors. Dev Biol. 2009;329:386-99 pubmed publisher
We have investigated the expression and function of the Sox15 transcription factor during the development of the external mechanosensory organs of Drosophila...
Laudet V, Stehelin D, Clevers H. Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res. 1993;21:2493-501 pubmed
..Finally, we provide a tree for the highly complex group of SRY-like ('Sox' genes), clustering at least 40 different loci that rapidly diverged in various animal lineages. ..
Dichtel Danjoy M, Caldeira J, Casares F. SoxF is part of a novel negative-feedback loop in the wingless pathway that controls proliferation in the Drosophila wing disc. Development. 2009;136:761-9 pubmed publisher
..uncover a new feedback loop in the wg pathway in which the spatially restricted activation of the Sox gene SoxF (Sox15) by wg represses its own transcription, thus ensuring tight regulation of growth control...
Denny P, Swift S, Brand N, Dabhade N, Barton P, Ashworth A. A conserved family of genes related to the testis determining gene, SRY. Nucleic Acids Res. 1992;20:2887 pubmed
Sessa L, Bianchi M. The evolution of High Mobility Group Box (HMGB) chromatin proteins in multicellular animals. Gene. 2007;387:133-40 pubmed
..The organization of HMGB genes was very conserved during Metazoan evolution, with the only deviations appearing in Caenorhabditis and Dipteran (Drosophila and Anopheles) species. ..
Cachero S, Simpson T, zur Lage P, Ma L, Newton F, Holohan E, et al
. The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons. PLoS Biol. 2011;9:e1000568 pubmed publisher
..In addition, it provides a paradigm for how transcriptional regulation may modulate the ciliogenesis pathway to give rise to structurally and functionally specialised ciliary dendrites. ..
Quan J, Saaem I, Tang N, Ma S, Negre N, Gong H, et al
. Parallel on-chip gene synthesis and application to optimization of protein expression. Nat Biotechnol. 2011;29:449-52 pubmed publisher
..This technology may facilitate systematic investigation of the molecular mechanisms of protein translation and the design, construction and evolution of macromolecular machines, metabolic networks and synthetic cells. ..
Soullier S, Jay P, Poulat F, Vanacker J, Berta P, Laudet V. Diversification pattern of the HMG and SOX family members during evolution. J Mol Evol. 1999;48:517-27 pubmed
..The various UBF boxes cannot be clustered together and their diversification appears to be extremely ancient, probably before the appearance of metazoans. ..
Cremazy F, Berta P, Girard F. Genome-wide analysis of Sox genes in Drosophila melanogaster. Mech Dev. 2001;109:371-5 pubmed
..Here we report the embryonic and larval expression pattern of four previously uncharacterized Sox genes, through antibody staining and in situ hybridization experiments. ..