Gene Symbol: snky
Description: sneaky
Alias: CG11281, Dmel\CG11281, ms(3)4, ms(3)ry4, ms(3)sneaky, ms(3)snky, sneaky, CG11281-PB, snky-PB
Species: fruit fly

Top Publications

  1. Fitch K, Wakimoto B. The paternal effect gene ms(3)sneaky is required for sperm activation and the initiation of embryogenesis in Drosophila melanogaster. Dev Biol. 1998;197:270-82 pubmed
    ..Here we describe the third strict paternal effect gene to be identified in Drosophila ms(3)sneaky(snky), which defines the earliest developmental arrest phenotype so far described...
  2. Wilson K, Fitch K, Bafus B, Wakimoto B. Sperm plasma membrane breakdown during Drosophila fertilization requires sneaky, an acrosomal membrane protein. Development. 2006;133:4871-9 pubmed
    ..We previously proposed that mutations in the sneaky (snky) gene result in male sterility due to failure in PMBD...
  3. Milan M, Weihe U, Perez L, Cohen S. The LRR proteins capricious and Tartan mediate cell interactions during DV boundary formation in the Drosophila wing. Cell. 2001;106:785-94 pubmed
  4. Ohsako T, Hirai K, Yamamoto M. The Drosophila misfire gene has an essential role in sperm activation during fertilization. Genes Genet Syst. 2003;78:253-66 pubmed
    ..These phenotypes were equivalent to those of sneaky (snky), another fertilization defective male sterile mutation...
  5. Sakurai K, Kojima T, Aigaki T, Hayashi S. Differential control of cell affinity required for progression and refinement of cell boundary during Drosophila leg segmentation. Dev Biol. 2007;309:126-36 pubmed
    ..Dynamic spatiotemporal regulation of cell affinity mediated by Capricious and Tartan is a key property of refinement of the Ta5/Pre boundary. ..
  6. Fitch K, Yasuda G, Owens K, Wakimoto B. Paternal effects in Drosophila: implications for mechanisms of early development. Curr Top Dev Biol. 1998;38:1-34 pubmed
    ..Analyses of the paternal effects mutations sneaky, K81, paternal loss, and Horka have identified paternal products that play a role in mediating the initial ..
  7. Smith M, Wakimoto B. Complex regulation and multiple developmental functions of misfire, the Drosophila melanogaster ferlin gene. BMC Dev Biol. 2007;7:21 pubmed publisher
    ..We demonstrate that Mfr is not required for localization of Sneaky, another membrane protein necessary for PMBD...
  8. Mao Y, Kerr M, Freeman M. Modulation of Drosophila retinal epithelial integrity by the adhesion proteins capricious and tartan. PLoS ONE. 2008;3:e1827 pubmed publisher
    ..We conclude that Capricious and Tartan contribute to the adhesive properties of the cells in the morphogenetic furrow and that this regulated adhesion participates in the control of spacing ommatidial clusters. ..
  9. Kohsaka H, Nose A. Target recognition at the tips of postsynaptic filopodia: accumulation and function of Capricious. Development. 2009;136:1127-35 pubmed publisher
    ..The nascent synaptic sites of M12 were also reduced. These results provide evidence for the sensing function of postsynaptic filopodia, and implicate Caps-mediated recognition at the tips of myopodia in synaptic matching. ..

More Information


  1. Desai B, Shirolikar S, Ray K. F-actin-based extensions of the head cyst cell adhere to the maturing spermatids to maintain them in a tight bundle and prevent their premature release in Drosophila testis. BMC Biol. 2009;7:19 pubmed publisher
    ..This is likely to regulate mature sperm release into the seminal vesicle. Overall, this process bears resemblance to mammalian spermiation. ..
  2. Spradling A, Rubin G. Transposition of cloned P elements into Drosophila germ line chromosomes. Science. 1982;218:341-7 pubmed
    ..Thus P elements can efficiently and selectively transpose from extrachromosomal DNA to the DNA of germ line chromosomes in Drosophila embryos. These observations provide the basis for efficient DNA-mediated gene transfer in Drosophila. ..
  3. Liu J, Lin H, Lopez J, Wolfner M. Formation of the male pronuclear lamina in Drosophila melanogaster. Dev Biol. 1997;184:187-96 pubmed
    ..Using a paternal effect mutation, snky, we found that recruitment of lamina proteins to the male pronucleus requires, and probably accompanies, ..
  4. Mirth C, Akam M. Joint development in the Drosophila leg: cell movements and cell populations. Dev Biol. 2002;246:391-406 pubmed
    ..These markers also define a number of more localised territories within the pupal joint. ..
  5. Bonnefoy E, Orsi G, Couble P, Loppin B. The essential role of Drosophila HIRA for de novo assembly of paternal chromatin at fertilization. PLoS Genet. 2007;3:1991-2006 pubmed
    ..Finally, we showed that H3.3 deposition is apparently not affected in Hira mutant embryos and adults, suggesting that different chromatin assembly machineries could deposit this histone variant. ..
  6. Loppin B, Dubruille R, Horard B. The intimate genetics of Drosophila fertilization. Open Biol. 2015;5: pubmed publisher
  7. Fari K, Takács S, Ungar D, Sinka R. The role of acroblast formation during Drosophila spermatogenesis. Biol Open. 2016;5:1102-10 pubmed publisher
    ..Moreover, these results suggest the importance of retrograde tethering complexes in the formation of a functional Golgi ribbon. ..