Gene Symbol: smallminded
Description: smallminded
Alias: CG8571, Dmel\CG8571, Smid, l(3)j6B8, l(3)j8A6, l(3)s2898, smallminded, CG8571-PA, CG8571-PC, CG8571-PG, CG8571-PH, CG8571-PI, small-minded, smid-PA, smid-PC, smid-PG, smid-PH, smid-PI
Species: fruit fly

Top Publications

  1. Long A, Wilkins J, Shepherd D. Dynamic developmental expression of smallminded, a Drosophila gene required for cell division. Mech Dev. 1998;76:33-43 pubmed
    Here we describe the expression pattern of the smallminded (smid) gene during Drosophila development and investigate the phenotype of a null mutant...
  2. Long A, Yang M, Kaiser K, Shepherd D. Isolation and characterisation of smallminded, a Drosophila gene encoding a new member of the Cdc48p/VCP subfamily of AAA proteins. Gene. 1998;208:191-9 pubmed
    b>Smallminded (smid) encodes a new member of the cdc48p/VCP subfamily of AAA proteins in Drosophila...
  3. Slack C, Somers W, Sousa Nunes R, Chia W, Overton P. A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions. BMC Genet. 2006;7:33 pubmed
    ..Taken together, these results demonstrate the value of mosaic screens in the identification of genes involved in neuroblast division. ..
  4. Wasser M, Bte Osman Z, Chia W. EAST and Chromator control the destruction and remodeling of muscles during Drosophila metamorphosis. Dev Biol. 2007;307:380-93 pubmed
    ..Overexpression of EAST-GFP can prevent the disintegration of polytene chromosomes during programmed cell death. We propose that Chro activates and east inhibits processes and genes involved in tissue destruction and remodeling. ..
  5. Svensson M, Stenberg P, Larsson J. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Dev Genes Evol. 2007;217:639-50 pubmed
    ..In addition, we show that the 50-70 C terminal amino acids of TrxT constitute a hyper-variable domain, which could play a role in sexual conflict and male-female co-evolution. ..
  6. Hwang R, Zhong L, Xu Y, Johnson T, Zhang F, Deisseroth K, et al. Nociceptive neurons protect Drosophila larvae from parasitoid wasps. Curr Biol. 2007;17:2105-2116 pubmed publisher
    ..The nociception behavior of Drosophila melanagaster larvae includes an innately encoded directional preference. Nociception behavior is elicited by the ecologically relevant sensory stimulus of parasitoid wasp attack. ..
  7. Williams D, Shepherd D. Persistent larval sensory neurons in adult Drosophila melanogaster. J Neurobiol. 1999;39:275-86 pubmed
    ..All of these neurons and their axons define specific adult sensory pathways in the periphery and their locations and persistence through metamorphosis suggest a role in guiding the growth of adult sensory and motor axons. ..
  8. Williams D, Tyrer M, Shepherd D. Tau and tau reporters disrupt central projections of sensory neurons in Drosophila. J Comp Neurol. 2000;428:630-40 pubmed
    ..The results also indicate that Drosophila may provide a useful model system for examining the role of tau in neurodegenerative disorders. ..
  9. Nagel J, Delandre C, Zhang Y, Forstner F, Moore A, Tavosanis G. Fascin controls neuronal class-specific dendrite arbor morphology. Development. 2012;139:2999-3009 pubmed publisher
    ..We propose that dedicated molecular mechanisms underlie the formation and dynamics of distinct dendrite branch types to elicit the accurate establishment of neuronal circuits. ..

More Information


  1. Tsubouchi A, Caldwell J, Tracey W. Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Curr Biol. 2012;22:2124-34 pubmed publisher
    ..These cells show physiological responses to force. Ion channels in several force-sensing gene families are required for behavioral sensitivity to touch and for the formation of the actin-rich sensory filopodia. ..
  2. Smith S, Shepherd D. Central afferent projections of proprioceptive sensory neurons in Drosophila revealed with the enhancer-trap technique. J Comp Neurol. 1996;364:311-23 pubmed
    ..The enhancer-trap technique provides a potentially powerful tool for describing the organisation of the central nervous system of Drosophila. ..
  3. Landgraf M, Sanchez Soriano N, Technau G, Urban J, Prokop A. Charting the Drosophila neuropile: a strategy for the standardised characterisation of genetically amenable neurites. Dev Biol. 2003;260:207-25 pubmed
    ..Using the Fasciclin2-based mapping procedure as a standard (e.g., in a common database) would facilitate studies on the functional architecture of the neuropile and the identification of candiate circuit elements. ..