SIFamide receptor


Gene Symbol: SIFamide receptor
Description: SIFamide receptor
Alias: CG10823, Dmel\CG10823, DrmSIFR, SIF-R, SIFR, SIFa-R, anon-WO0170980.43, anon-WO0170980.44, SIFamide receptor, CG10823-PA, CG10823-PC, SIFaR-PA, SIFaR-PC, SIFamide-receptor
Species: fruit fly

Top Publications

  1. Paik D, Jang Y, Lee Y, Lee Y, Yamamoto R, Gee H, et al. Misexpression screen delineates novel genes controlling Drosophila lifespan. Mech Ageing Dev. 2012;133:234-45 pubmed publisher
  2. J rgensen L, Hauser F, Cazzamali G, Williamson M, Grimmelikhuijzen C. Molecular identification of the first SIFamide receptor. Biochem Biophys Res Commun. 2006;340:696-701 pubmed publisher
    ..Here, we have identified the Drosophila gene (CG10823) coding for the SIFamide receptor. When expressed in Chinese hamster ovary cells, the receptor is only activated by Drosophila SIFamide (EC(50)..
  3. Agrawal T, Sadaf S, Hasan G. A genetic RNAi screen for IP?/Ca²? coupled GPCRs in Drosophila identifies the PdfR as a regulator of insect flight. PLoS Genet. 2013;9:e1003849 pubmed publisher
  4. Johnson E, Tift F, McCauley A, Liu L, Roman G. Functional characterization of kurtz, a Drosophila non-visual arrestin, reveals conservation of GPCR desensitization mechanisms. Insect Biochem Mol Biol. 2008;38:1016-22 pubmed publisher
    ..Furthermore, we report that kurtz mutants exhibit hypersensitivity to osmotic stress, implicating GPCR desensitization as an important feature of the endocrine events that shape this stress response. ..
  5. Park S, Sonn J, Oh Y, Lim C, Choe J. SIFamide and SIFamide receptor defines a novel neuropeptide signaling to promote sleep in Drosophila. Mol Cells. 2014;37:295-301 pubmed publisher
    b>SIFamide receptor (SIFR) is a Drosophila G protein-coupled receptor for the neuropeptide SIFamide (SIFa)...
  6. Sellami A, Veenstra J. SIFamide acts on fruitless neurons to modulate sexual behavior in Drosophila melanogaster. Peptides. 2015;74:50-6 pubmed publisher
    ..However, when fruitless neurons are made to express RNAi specific for the SIFamide receptor, male flies engage in bisexual behavior, showing that SIFamide acts on fruitless neurons...
  7. Jayakumar S, Richhariya S, Reddy O, Texada M, Hasan G. Drosophila larval to pupal switch under nutrient stress requires IP3R/Ca(2+) signalling in glutamatergic interneurons. elife. 2016;5: pubmed publisher
    ..Activity in this circuit is thus likely to be an adaptation that provides a layer of regulation to help surpass nutritional stress during development. ..