Gene Symbol: Rtnl2
Alias: CG1279, Dmel\CG1279, Tml84D, anon-WO0170980.134, rtnl2, trop, Rtnl2, CG1279-PB, CG1279-PC, Rtnl2-PB, Rtnl2-PC, Tropomyosin-like-84D, tropomyosin-like
Species: fruit fly
Robin G, Russell R, Cutler D, Oakeshott J. The evolution of an alpha-esterase pseudogene inactivated in the Drosophila melanogaster lineage. Mol Biol Evol. 2000;17:563-75 pubmed publisher
..We argue that the original alphaE4a gene had a function which it has lost since the divergence of the D. melanogaster and D. simulans lineages...
Robin C, Russell R, Medveczky K, Oakeshott J. Duplication and divergence of the genes of the alpha-esterase cluster of Drosophila melanogaster. J Mol Evol. 1996;43:241-52 pubmed
..The distribution of indels also suggests a deeper node in the gene phylogeny that separates six genes at the two ends of the cluster from a block of five in the middle. ..
Russell R, Robin G, Kostakos P, Newcomb R, Boyce T, Medveczky K, et al
. Molecular cloning of an alpha-esterase gene cluster on chromosome 3r of Drosophila melanogaster. Insect Biochem Mol Biol. 1996;26:235-47 pubmed
..We argue that we have cloned the D. melanogaster version of a major cluster of esterase genes which have variously mutated to confer organophosphate resistance in diverse Diptera. ..
de Q Robin G, Claudianos C, Russell R, Oakeshott J. Reconstructing the diversification of alpha-esterases: comparing the gene clusters of Drosophila buzzatii and D. melanogaster. J Mol Evol. 2000;51:149-60 pubmed
Mattie F, Stackpole M, Stone M, Clippard J, Rudnick D, Qiu Y, et al
. Directed microtubule growth, +TIPs, and kinesin-2 are required for uniform microtubule polarity in dendrites. Curr Biol. 2010;20:2169-77 pubmed publisher
..This represents a newly discovered mechanism for maintaining polarized arrays of microtubules. ..
Chen L, Stone M, Tao J, Rolls M. Axon injury and stress trigger a microtubule-based neuroprotective pathway. Proc Natl Acad Sci U S A. 2012;109:11842-7 pubmed publisher
..We conclude that axon injury or stress triggers a microtubule-based neuroprotective pathway that stabilizes neurons against degeneration. ..
Weiner A, Lanz M, Goetschius D, Hancock W, Rolls M. Kinesin-2 and Apc function at dendrite branch points to resolve microtubule collisions. Cytoskeleton (Hoboken). 2016;73:35-44 pubmed publisher
..However, when kinesin-2 was reduced some microtubules grew straight through the branch point and failed to turn. We propose that kinesin-2 functions to steer growing microtubules along stable ones following collisions. ..