Gene Symbol: rpk
Description: ripped pocket
Alias: CG1058, Dmel\CG1058, GNaC1, RPK, dGNaC1, ppk2, ripped pocket, CG1058-PA, CG1058-PB, gonad-specific amiloride-sensitive sodium channel 1, rpk-PA, rpk-PB
Species: fruit fly
Horner V, Wolfner M. Mechanical stimulation by osmotic and hydrostatic pressure activates Drosophila oocytes in vitro in a calcium-dependent manner. Dev Biol. 2008;316:100-9 pubmed publisher
..This will allow exploitation of Drosophila genetics to dissect molecular pathways involving Ca(2+) and the activation of development. ..
Bono J, Matzkin L, Kelleher E, Markow T. Postmating transcriptional changes in reproductive tracts of con- and heterospecifically mated Drosophila mojavensis females. Proc Natl Acad Sci U S A. 2011;108:7878-83 pubmed publisher
Tsubouchi A, Caldwell J, Tracey W. Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Curr Biol. 2012;22:2124-34 pubmed publisher
..Through a genome-wide RNAi screen of ion channels, we identified Ripped Pocket (rpk), No Mechanoreceptor Potential C (nompC), and NMDA Receptors 1 and 2 (Nmdars) as playing critical roles ..
Hunter G, Crawford J, Genkins J, Kiehart D. Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure. Development. 2014;141:325-34 pubmed publisher
..We identify two channel subunits, ripped pocket and dtrpA1 (TrpA1), that play a role in closure and other morphogenetic events...
Mutsuddi M, Nambu J. Neural disease: Drosophila degenerates for a good cause. Curr Biol. 1998;8:R809-11 pubmed
..Recent studies suggest that molecular genetic approaches in Drosophila may shed important new light on conserved mechanisms underlying such disorders. ..
Mano I, Driscoll M. DEG/ENaC channels: a touchy superfamily that watches its salt. Bioessays. 1999;21:568-78 pubmed
..We discuss working understanding of DEG/ENaC functions, channel properties, structure/activity correlations and possible evolutionary relationship to other channel classes. ..
Guo Y, Wang Y, Wang Q, Wang Z. The role of PPK26 in Drosophila larval mechanical nociception. Cell Rep. 2014;9:1183-90 pubmed
..Our work indicates that PPK26 and PPK might form heteromeric DEG/ENaC channels that are essential for mechanotransduction in class IV da neurons. ..
Adams C, Anderson M, Motto D, Price M, Johnson W, Welsh M. Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons. J Cell Biol. 1998;140:143-52 pubmed
..We identified two novel Drosophila DEG/ ENaC proteins, Pickpocket (PPK) and Ripped Pocket (RPK). Both appear to be ion channel subunits...
Darboux I, Lingueglia E, Champigny G, Coscoy S, Barbry P, Lazdunski M. dGNaC1, a gonad-specific amiloride-sensitive Na+ channel. J Biol Chem. 1998;273:9424-9 pubmed
..We have now identified a gene called dGNaC1 that is specifically expressed in the gonads and early embryo in Drosophila melanogaster...