Rab18

Summary

Gene Symbol: Rab18
Description: Rab18
Alias: 24639915, AAF46057, CG3129, DRABR4, DRabRP4, DmRab18, Dmel\CG3129, O18337, Rab-RP4, Rab-r4, Rab18/RP4, rab18, Rab18, CG3129-PA, Rab18-PA, rab-related protein 4
Species: fruit fly
Products:     Rab18

Top Publications

  1. Armstrong J. Membrane traffic between genomes. Genome Biol. 2000;1:REVIEWS104 pubmed
    ..A comparison of these families from the budding yeast, fission yeast, nematode and fruitfly genomes has implications for the organization of membrane traffic in different organisms. ..
  2. Chan C, Scoggin S, Wang D, Cherry S, Dembo T, Greenberg B, et al. Systematic discovery of Rab GTPases with synaptic functions in Drosophila. Curr Biol. 2011;21:1704-15 pubmed publisher
    ..The tools presented here allow systematic functional studies of these Rabs and provide a method that is applicable to any large gene family in Drosophila. ..
  3. Garg A, Wu L. Drosophila Rab14 mediates phagocytosis in the immune response to Staphylococcus aureus. Cell Microbiol. 2014;16:296-310 pubmed publisher
    ..Rab14 mutant haemocytes show impaired recruitment of Rab7 and of a lysosomal marker onto S.?aureus phagosomes. The defect in phagocytosis is associated with higher bacterial load and increased susceptibility to S.?aureus in the animal. ..
  4. White J, Anderson E, Zimmerman K, Zheng K, Rouhani R, Gunawardena S. Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo. Hum Mol Genet. 2015;24:7182-95 pubmed publisher
    ..These findings have important implications for our understanding of the complex role HTT plays within neurons normally, which when disrupted may lead to neuronal death and disease. ..
  5. Riedel F, Galindo A, Muschalik N, Munro S. The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases. J Cell Biol. 2018;217:601-617 pubmed publisher
    ..Thus, in metazoans, Rab1 activation requires TRAPP subunits not found in yeast, and Rab11 activation is shared by TRAPPII and an unrelated GEF that is metazoan specific. ..
  6. Satoh A, Tokunaga F, Ozaki K. Rab proteins of Drosophila melanogaster: novel members of the Rab-protein family. FEBS Lett. 1997;404:65-9 pubmed
    ..However, both contain all amino acids conserved in known Rabs. In addition, DRabRP4 has strong GTP-binding activity, when synthesized in E. coli cells...
  7. Ma Z, Liu Z, Huang X. Membrane phospholipid asymmetry counters the adverse effects of sterol overloading in the Golgi membrane of Drosophila. Genetics. 2012;190:1299-308 pubmed publisher