POLDIP2

Summary

Gene Symbol: POLDIP2
Description: Polymerase (DNA-directed), delta interacting protein 2
Alias: CG12162, Dmel\CG12162, polymerase (DNA-directed), delta interacting protein 2, CG12162-PA, CG12162-PB, POLDIP2-PA, POLDIP2-PB
Species: fruit fly

Top Publications

  1. Svensson M, Stenberg P, Larsson J. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Dev Genes Evol. 2007;217:639-50 pubmed
    ..In addition, we show that the 50-70 C terminal amino acids of TrxT constitute a hyper-variable domain, which could play a role in sexual conflict and male-female co-evolution. ..
  2. Kim Y, Park H, Nah J, Moon S, Lee W, Hong S, et al. Essential role of POLDIP2 in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition. Biochem Biophys Res Commun. 2015;462:112-8 pubmed publisher
    ..In a drosophila model of human tauopathy, knockdown of the drosophila POLDIP2 homolog, CG12162, attenuated rough eye phenotype induced by Tau overexpression...

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