Nup93-1

Summary

Gene Symbol: Nup93-1
Description: Nucleoporin 93kD-1
Alias: BcDNA:LD21129, CG11092, Dmel\CG11092, Nup93, nup93, nucleoporin 93kD-1, CG11092-PA, Nup93-1-PA
Species: fruit fly

Top Publications

  1. Busayavalasa K, Chen X, Farrants A, Wagner N, Sabri N. The Nup155-mediated organisation of inner nuclear membrane proteins is independent of Nup155 anchoring to the metazoan nuclear pore complex. J Cell Sci. 2012;125:4214-8 pubmed publisher
    ..a combination of protein binding and rescue assays to map the interaction sites of two neighbouring NPC proteins Nup93 and Nup53 on Nup155, and to define the requirements of these interactions in INM protein organization...
  2. Breuer M, Ohkura H. A negative loop within the nuclear pore complex controls global chromatin organization. Genes Dev. 2015;29:1789-94 pubmed publisher
    ..propose a negative regulatory loop within the NPC controlling the chromatin attachment state, in which Nup155 and Nup93 recruit Nup62 to suppress chromatin tethering by Nup155...
  3. Chen X, Xu L. Specific nucleoporin requirement for Smad nuclear translocation. Mol Cell Biol. 2010;30:4022-34 pubmed publisher
    ..Surprisingly, many of these nucleoporins, including Sec13, Nup75, Nup93, and Nup205, are scaffold nucleoporins considered important for the overall integrity of the nuclear pore complex (..
  4. Asensio C, Sirkis D, Edwards R. RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway. J Cell Biol. 2010;191:1173-87 pubmed publisher
    ..Although vesicles with a dense core still form in the absence of AP-3, they contain substantially less synaptotagmin 1, indicating that AP-3 concentrates the proteins required for regulated exocytosis. ..
  5. Pascual GarcĂ­a P, Debo B, Aleman J, Talamas J, Lan Y, Nguyen N, et al. Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts. Mol Cell. 2017;66:63-76.e6 pubmed publisher
    ..Together, our data identify Nups as a class of architectural proteins for enhancers and supports a model in which animal genomes use the nuclear pore as an organizing scaffold for inducible poised genes. ..