Nup62

Summary

Gene Symbol: Nup62
Description: Nucleoporin 62kD
Alias: CG6251, Dmel\CG6251, p62, nucleoporin 62kD, CG6251-PA, CG6251-PB, Nup62-PA, Nup62-PB, nucleoporin, nucleoporin 62
Species: fruit fly

Top Publications

  1. Bhattacharya A, Steward R. The Drosophila homolog of NTF-2, the nuclear transport factor-2, is essential for immune response. EMBO Rep. 2002;3:378-83 pubmed
    ..We also found that DNTF-2 interacts directly with Mbo/DNup88, which does not contain phenylalanine-glycine-rich repeats, but has been shown to function in the import of Rel proteins. ..
  2. Breuer M, Ohkura H. A negative loop within the nuclear pore complex controls global chromatin organization. Genes Dev. 2015;29:1789-94 pubmed publisher
    ..regulatory loop within the NPC controlling the chromatin attachment state, in which Nup155 and Nup93 recruit Nup62 to suppress chromatin tethering by Nup155...
  3. Kalverda B, Pickersgill H, Shloma V, Fornerod M. Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm. Cell. 2010;140:360-71 pubmed publisher
    ..We have functionally characterized nucleoporin-chromatin interactions specifically at the NPC or within the nucleoplasm in Drosophila...
  4. Burns L, Wente S. From hypothesis to mechanism: uncovering nuclear pore complex links to gene expression. Mol Cell Biol. 2014;34:2114-20 pubmed publisher
    ..These examples highlight new and unpredicted mechanisms for Nup impacts on transcription and questions that are left to be explored. ..
  5. Osouda S, Nakamura Y, de Saint Phalle B, McConnell M, Horigome T, Sugiyama S, et al. Null mutants of Drosophila B-type lamin Dm(0) show aberrant tissue differentiation rather than obvious nuclear shape distortion or specific defects during cell proliferation. Dev Biol. 2005;284:219-32 pubmed
    ..In contrast, both gonadal and CNS tissues exhibited underdevelopment. ..