Nhe3

Summary

Gene Symbol: Nhe3
Description: Na[+]/H[+] hydrogen exchanger 3
Alias: CG11328, DmNHE3, Dmel\CG11328, NHE3, nhe3, Na[+]/H[+] hydrogen exchanger 3, CG11328-PD, CG11328-PE, CG11328-PG, CG11328-PH, CG11328-PI, CG11328-PJ, Nhe3-PD, Nhe3-PE, Nhe3-PG, Nhe3-PH, Nhe3-PI, Nhe3-PJ
Species: fruit fly

Top Publications

  1. Patel A, McCarthy M, Steitz J. The splicing of U12-type introns can be a rate-limiting step in gene expression. EMBO J. 2002;21:3804-15 pubmed
    ..These results provide evidence that the level of gene expression in vivo is lowered by the presence of a U12-type intron and implicate the U12-type spliceosome as a target in the post-transcriptional regulation of gene expression. ..
  2. Schneider C, Will C, BROSIUS J, Frilander M, Luhrmann R. Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proc Natl Acad Sci U S A. 2004;101:9584-9 pubmed
    ..A comparison of U11 snRNAs that we have identified from vertebrates, plants, and insects, suggests that an evolutionarily divergent U11 snRNA may be unique to Drosophila and not characteristic of insects in general. ..
  3. Day J, Wan S, Allan A, Kean L, Davies S, Gray J, et al. Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa. J Cell Sci. 2008;121:2612-9 pubmed publisher
    ..Thus, both CG10806 and CG31052 are functionally members of the CPA2 gene family, colocalise to the same apical membrane as the plasma membrane V-ATPase and show distinct ion specificities, as expected for the Wieczorek exchanger. ..
  4. Park D, Hadzic T, Yin P, Rusch J, Abruzzi K, Rosbash M, et al. Molecular organization of Drosophila neuroendocrine cells by Dimmed. Curr Biol. 2011;21:1515-24 pubmed publisher
    ..The results provide a rigorous molecular framework with which to describe the fundamental regulatory organization of diverse neuroendocrine cells. ..
  5. Adolph K. A thrombospondin homologue in Drosophila melanogaster: cDNA and protein structure. Gene. 2001;269:177-84 pubmed
    ..Alignment of the amino acid sequences of the Drosophila TSP with human TSP1-TSP4 and COMP demonstrated a high degree of homology between the four Type II repeats, seven Type III repeats, and C-terminal domain. ..
  6. Lin C, Mount S, Jarmołowski A, Makałowski W. Evolutionary dynamics of U12-type spliceosomal introns. BMC Evol Biol. 2010;10:47 pubmed publisher
    ..Loss of U12 introns or the genes containing them is more common than conversion to the U2-type. The degeneracy of U12-type terminal dinucleotides among natural U12-type introns is higher than previously thought. ..
  7. Praveen K, Wen Y, Matera A. A Drosophila model of spinal muscular atrophy uncouples snRNP biogenesis functions of survival motor neuron from locomotion and viability defects. Cell Rep. 2012;1:624-31 pubmed publisher
    ..These findings have major implications for SMA etiology because they show that SMN's role in snRNP biogenesis can be uncoupled from the organismal viability and locomotor defects. ..