Gene Symbol: Mppe
Description: Metallophosphoesterase
Alias: 11471, CG8889, Dmel\CG8889, GS11471, dMPPE, dmppe, metallophosphoesterase, CG8889-PA, CG8889-PB, CG8889-PD, CG8889-PE, Mppe-PA, Mppe-PB, Mppe-PD, Mppe-PE
Species: fruit fly
Products:     Mppe

Top Publications

  1. Cao J, Li Y, Xia W, Reddig K, Hu W, Xie W, et al. A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin. EMBO J. 2011;30:3701-13 pubmed publisher
    ..Here, we identify a dmppe (Drosophila metallophosphoesterase) mutant with incomplete deglycosylation of Rh1, and show that the retained oligosaccharide chain does not ..
  2. Kim J, Kim Y, Kim Ha J. Blood-brain barrier defects associated with Rbp9 mutation. Mol Cells. 2010;29:93-8 pubmed publisher
    ..Putative Rbp9-binding sites were found in introns of genes that function in cell adhesion. Therefore, Rbp9 may regulate the splicing of cell adhesion molecules, critical for the formation of the BBB...
  3. Voolstra O, Bartels J, Oberegelsbacher C, Pfannstiel J, Huber A. Phosphorylation of the Drosophila transient receptor potential ion channel is regulated by the phototransduction cascade and involves several protein kinases and phosphatases. PLoS ONE. 2013;8:e73787 pubmed publisher
    ..A candidate screen to identify kinases and phosphatases provided in vivo evidence for an involvement of eye-PKC as well as other kinases and phosphatases in TRP phosphorylation. ..
  4. Satoh T, Ohba A, Liu Z, Inagaki T, Satoh A. dPob/EMC is essential for biosynthesis of rhodopsin and other multi-pass membrane proteins in Drosophila photoreceptors. elife. 2015;4: pubmed publisher
    ..These results collectively indicate that EMC is a key factor in the biogenesis of multi-pass transmembrane proteins, including Rh1, and its loss causes retinal degeneration. ..
  5. Kunduri G, Yuan C, Parthibane V, Nyswaner K, Kanwar R, Nagashima K, et al. Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors. J Cell Biol. 2014;206:79-95 pubmed publisher
    ..Our findings show that a cytosolic protein is necessary for transit of selective transmembrane receptor cargo by the COPII coat for anterograde trafficking. ..