Mpp6

Summary

Gene Symbol: Mpp6
Description: M-phase phosphoprotein 6
Alias: BcDNA:RE45276, CG9250, Dmel\CG9250, MPP6, Mpps, dMPP6, l(2)k16403, mpp6, M-phase phosphoprotein 6, CG9250-PA, CG9250-PB, Mpp6-PA, Mpp6-PB
Species: fruit fly

Top Publications

  1. Frolov M, Huen D, Stevaux O, Dimova D, Balczarek Strang K, Elsdon M, et al. Functional antagonism between E2F family members. Genes Dev. 2001;15:2146-60 pubmed
    ..This study shows how repressor and activator E2Fs are used to pattern transcription and how the net effect of E2F on cell proliferation results from the interplay between two types of E2F complexes that have antagonistic functions. ..
  2. Moon N, Frolov M, Kwon E, Di Stefano L, Dimova D, Morris E, et al. Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development. Dev Cell. 2005;9:463-75 pubmed
    ..These loss-of-function experiments demonstrate that E2F cannot be classified simply as a pro- or antiapoptotic factor. Instead, the overall role of E2F in the damage response varies greatly and depends on the cellular context. ..
  3. Cayirlioglu P, Bonnette P, Dickson M, Duronio R. Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells. Development. 2001;128:5085-98 pubmed
    ..These data indicate that E2f2 functions to inhibit widespread genomic DNA synthesis in late stage follicle cells, and may do so by repressing the expression of specific components of the replication machinery. ..