Gene Symbol: Mob2
Alias: BEST:GH06341, BcDNA:GH13236, CG11711, CG11712, DMob2, Dmel\CG11711, Dmob1, Dmob2, Mob1, MobI, dmob2, gh06341, trezor, Mob2, CG11711-PA, CG11711-PB, CG11711-PC, CG11711-PD, CG11711-PE, Mob2-PA, Mob2-PB, Mob2-PC, Mob2-PD, Mob2-PE
Species: fruit fly
He Y, Emoto K, Fang X, Ren N, Tian X, Jan Y, et al
. Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases. Mol Biol Cell. 2005;16:4139-52 pubmed
..Interestingly, the overgrowth tumor phenotype that results from mutations in Dmob1 (mats) was only seen in genetic mosaics and not when the entire animal was mutant...
Brown E, Layne J, Zhu C, Jegga A, Rollmann S. Genome-wide association mapping of natural variation in odour-guided behaviour in Drosophila. Genes Brain Behav. 2013;12:503-15 pubmed publisher
..Our results showed that subtle changes influencing nervous system function can result in marked differences in behaviour. ..
Berger K, Kong E, Dubnau J, Tully T, Moore M, Heberlein U. Ethanol sensitivity and tolerance in long-term memory mutants of Drosophila melanogaster. Alcohol Clin Exp Res. 2008;32:895-908 pubmed publisher
..The corresponding genes in these mutants represent areas of potential overlap between learning and memory and behavioral responses to alcohol. These genes also define components shared between different ethanol behavioral responses. ..
Telonis Scott M, Kopp A, Wayne M, Nuzhdin S, McIntyre L. Sex-specific splicing in Drosophila: widespread occurrence, tissue specificity and evolutionary conservation. Genetics. 2009;181:421-34 pubmed publisher
..females. We found that all six loci are themselves spliced sex specifically in gonads and heads, suggesting that regulatory hierarchies based on alternative splicing may be an important feature of sexual differentiation. ..
van Swinderen B, McCartney A, Kauffman S, Flores K, Agrawal K, Wagner J, et al
. Shared visual attention and memory systems in the Drosophila brain. PLoS ONE. 2009;4:e5989 pubmed publisher
Liu L, Lin C, Fan S. Function of Drosophila mob2 in photoreceptor morphogenesis. Cell Tissue Res. 2009;338:377-89 pubmed publisher
..genes involved in determining stalk and rhabdomere formation, this study has identified the Drosophila mob2 (Dmob2) gene...
Akalal D, Yu D, Davis R. The long-term memory trace formed in the Drosophila ?/? mushroom body neurons is abolished in long-term memory mutants. J Neurosci. 2011;31:5643-7 pubmed publisher
..These observations elevate the significance of this LTM trace given that 26 independent mutants all exhibit a defect in the trace, and further suggest that the calcium trace is a fundamental mechanism underlying Drosophila LTM...
Schulte J, Sepp K, Jorquera R, Wu C, Song Y, Hong P, et al
. DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. J Neurosci. 2010;30:5189-203 pubmed publisher
..Models for Mob function are primarily based on studies of Mob1 and Mob2 family members in yeast...
Campbell M, Ganetzky B. Identification of Mob2, a novel regulator of larval neuromuscular junction morphology, in natural populations of Drosophila melanogaster. Genetics. 2013;195:915-26 pubmed publisher
..Focusing on one subline, that displayed NMJ overgrowth, we mapped the phenotype to Mob2 [Monopolar spindle (Mps) one binding protein 2)], a gene encoding a Nuclear Dbf2 (Dumbbell formation 2)-Related (..