mei-9

Summary

Gene Symbol: mei-9
Description: meiotic 9
Alias: CG3697, DhR1, DmXPF, Dmel\CG3697, MEI-9, Mei-9, Rad1p, mei9, mus(1)110, mus110, xpf/mei-9, meiotic 9, CG3697-PA, CG3697-PB, mei-9-PA, mei-9-PB, meiotic-9
Species: fruit fly
Products:     mei-9

Top Publications

  1. Todo T, Ryo H. Identification of cellular factors that recognize UV-damaged DNA in Drosophila melanogaster. Mutat Res. 1992;273:85-93 pubmed
    ..These findings might suggest the possible involvement of these gene products in lesion recognition and repair of UV-induced photoproducts in DNA. ..
  2. Venugopal S, Guzder S, Deutsch W. Apurinic endonuclease activity from wild-type and repair-deficient mei-9 Drosophila ovaries. Mol Gen Genet. 1990;221:421-6 pubmed
  3. Margulies L. A high level of hybrid dysgenesis in Drosophila: high thermosensitivity, dependence on DNA repair, and incomplete cytotype regulation. Mol Gen Genet. 1990;220:448-55 pubmed
    ..The relatively high premature sterility of cross B DNA repair-deficient males, reared at 18 degrees C and aged at 21 degrees C, indicates that there is incomplete cytotype regulation in Hs subline hybrids. ..
  4. Yildiz O, Kearney H, Kramer B, Sekelsky J. Mutational analysis of the Drosophila DNA repair and recombination gene mei-9. Genetics. 2004;167:263-73 pubmed
  5. Boyd J, Golino M, Setlow R. The mei-9 alpha mutant of Drosophila melanogaster increases mutagen sensitivity and decreases excision repair. Genetics. 1976;84:527-44 pubmed
    ..These studies demonstrate that currently recognized modes of DNA repair can be efficiently detected in primary cell cultures derived from Drosophila embryos. ..
  6. Carpenter A, Sandler L. On recombination-defective meiotic mutants in Drosophila melanogaster. Genetics. 1974;76:453-75 pubmed
  7. Yildiz O, Majumder S, Kramer B, Sekelsky J. Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers. Mol Cell. 2002;10:1503-9 pubmed
    ..We propose that MUS312 facilitates resolution of meiotic Holliday junction intermediates by MEI-9. ..
  8. McKim K, Dahmus J, Hawley R. Cloning of the Drosophila melanogaster meiotic recombination gene mei-218: a genetic and molecular analysis of interval 15E. Genetics. 1996;144:215-28 pubmed
    ..The mei-218 gene is predicted to produce an 1186-amino acid protein that has no significant similarities to any known proteins. ..
  9. Liu H, Jang J, Graham J, Nycz K, McKim K. Two genes required for meiotic recombination in Drosophila are expressed from a dicistronic message. Genetics. 2000;154:1735-46 pubmed
    ..These phenotypes are most similar to mutants of the mei-218 gene. This is striking because mei-217 and mei-218 are part of the same transcription unit and are most likely produced from a dicistronic message. ..

More Information

Publications80

  1. Blanton H, Radford S, McMahan S, Kearney H, Ibrahim J, Sekelsky J. REC, Drosophila MCM8, drives formation of meiotic crossovers. PLoS Genet. 2005;1:e40 pubmed
  2. Radford S, Goley E, Baxter K, McMahan S, Sekelsky J. Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers. Genetics. 2005;170:1737-45 pubmed
    ..We conclude that MEI-9 can generate some meiotic crossovers in an ERCC1-independent manner. ..
  3. Hawley R. Meiosis as an "M" thing: twenty-five years of meiotic mutants in Drosophila. Genetics. 1993;135:613-8 pubmed
  4. Joyce E, Tanneti S, McKim K. Drosophila hold'em is required for a subset of meiotic crossovers and interacts with the dna repair endonuclease complex subunits MEI-9 and ERCC1. Genetics. 2009;181:335-40 pubmed publisher
    ..Furthermore, HDM physically interacts with both MEI-9 and ERCC1 in a yeast two-hybrid assay. We conclude that HDM, MEI-9, MUS312, and ERCC1 form a complex that resolves meiotic recombination intermediates into crossovers. ..
  5. Joyce E, McKim K. Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation. Genetics. 2009;181:39-51 pubmed publisher
    ..Interestingly, PCH2-dependent delays in prophase may allow additional crossovers to form. ..
  6. Bhagat R, Manheim E, Sherizen D, McKim K. Studies on crossover-specific mutants and the distribution of crossing over in Drosophila females. Cytogenet Genome Res. 2004;107:160-71 pubmed
    ..This may be the activation of a regulatory system that ensures at least one crossover per chromosome, and which compensates for an absence of crossovers by attempting to generate them at random locations. ..
  7. Sekelsky J, McKim K, Chin G, Hawley R. The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1. Genetics. 1995;141:619-27 pubmed
    ..cerevisiae, in that it requires an NER protein. The biochemical properties of the Rad1 protein allow us to explain the observation that mei-9 mutants suppress reciprocal exchange without suppressing the frequency of gene conversion. ..
  8. Sekelsky J, Burtis K, Hawley R. Damage control: the pleiotropy of DNA repair genes in Drosophila melanogaster. Genetics. 1998;148:1587-98 pubmed
  9. Flores C, Engels W. Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants. Proc Natl Acad Sci U S A. 1999;96:2964-9 pubmed
    ..Contrary to the case in mammalian cells, spel1 deficiency does not affect tolerance of flies to a methylating agent nor does it affect resistance to gamma-irradiation. ..
  10. Baker B, Carpenter A. Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster. Genetics. 1972;71:255-86 pubmed
  11. Curtis D, Bender W. Gene conversion in Drosophila and the effects of the meiotic mutants mei-9 and mei-218. Genetics. 1991;127:739-46 pubmed
    ..Some unusual conversion events were found in the mei-218 and mei-9 samples, although most events were indistinguishable from wild-type tracts in their length and continuity. ..
  12. McKim K, Jang J, Theurkauf W, Hawley R. Mechanical basis of meiotic metaphase arrest. Nature. 1993;362:364-6 pubmed
    ..We conclude that metaphase arrest results from the balancing of kinetochore forces due to chiasmata. ..
  13. Vogel E, Nivard M. The response of germ cells to ethylene oxide, propylene oxide, propylene imine and methyl methanesulfonate is a matter of cell stage-related DNA repair. Environ Mol Mutagen. 1997;29:124-35 pubmed
    ..1990): Environ Mol Mutagen 16:126-131]. ..
  14. Kuzhir T, Goncharova R. Some effects of 1,4-dihydroisonicotinic acid derivatives on repair pathways involved in chemical mutagenesis. Biochem Soc Trans. 1997;25:139S pubmed
  15. Smith P, Baumen C, Dusenbery R. Mutagen sensitivity of Drosophila melanogaster. VI. Evidence from the excision-defective mei-9AT1 mutant for the timing of DNA-repair activity during spermatogenesis. Mutat Res. 1983;108:175-84 pubmed
    ..By analogy with these studies, we speculate that mei-9, like uvr D, is deficient in a DNA unwinding protein. ..
  16. Ashburner M, Ball C, Blake J, Botstein D, Butler H, Cherry J, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000;25:25-9 pubmed
  17. Jassim O, Fink J, Cagan R. Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response. EMBO J. 2003;22:5622-32 pubmed
    ..These in vivo results demonstrate that the cellular effects of DNA damage depend on the developmental status of the tissue. ..
  18. Baker B, Smith D. The effects of mutagen-sensitive mutants of Drosophila melanogaster in nonmutagenized cells. Genetics. 1979;92:833-47 pubmed
    ..These comparisons show that the extant alleles at the mus-101, mus-109 and mus-105 loci are all leaky mutants. It is suggested that all three of these loci may specify essential mitotic functions. ..
  19. Brown T, Boyd J. Postreplication repair-defective mutants of Drosophila melanogaster fall into two classes. Mol Gen Genet. 1981;183:356-62 pubmed
    ..Of the five mutations that diminish postreplication repair, only two reduce the ability of irradiated cells to synthesize normal amounts of DNA. ..
  20. Koana T, Takahashi T, Tsujimura H. Reduction of spontaneous somatic mutation frequency by a low-dose X irradiation of Drosophila larvae and possible involvement of DNA single-strand damage repair. Radiat Res. 2012;177:265-71 pubmed
    ..It is hypothesized that some of the small spots resulted from single-strand damage and, in wild-type larvae, 0.2 Gy radiation activated the normal single-strand break repair gene, which reduced the background somatic mutation frequency. ..
  21. Lashmanova E, Proshkina E, Zhikrivetskaya S, Shevchenko O, Marusich E, Leonov S, et al. Fucoxanthin increases lifespan of Drosophila melanogaster and Caenorhabditis elegans. Pharmacol Res. 2015;100:228-41 pubmed publisher
    ..elegans were revealed only for fucoxanthin. In presence of carotenoids decreased flies' fecundity, increased spontaneous locomotor activity and resistance to oxidative stress were detected. ..
  22. Heyer W, Ehmsen K, Solinger J. Holliday junctions in the eukaryotic nucleus: resolution in sight?. Trends Biochem Sci. 2003;28:548-57 pubmed
    ..Holliday junction resolution to non-crossover products can also be achieved topologically, for example, by the action of RecQ-like DNA helicases combined with topoisomerase III. ..
  23. Smith A, King J, Orr Weaver T. Identification of genomic regions required for DNA replication during Drosophila embryogenesis. Genetics. 1993;135:817-29 pubmed
    ..Additionally, our analysis identified a gene, pimples, that is required for the proper completion of mitosis in the post-blastoderm divisions of the embryo. ..
  24. Inoue H, Baba H, Awano K, Yoshikawa K. Genotoxic effect of griseofulvin in somatic cells of Drosophila melanogaster. Mutat Res. 1995;343:229-34 pubmed
    ..It is noted that (1) GF-fed larvae showed a developmental delay and (2) surviving adult flies had morphological abnormalities in their eyes and wings. ..
  25. Eeken J, Sobels F, Hyland V, Schalet A. Distribution of MR-induced sex-linked recessive lethal mutations in Drosophila melanogaster. Mutat Res. 1985;150:261-75 pubmed
  26. Ferro W, Eeken J. Studies on mutagen sensitive strains of Drosophila melanogaster. XI. Survival (dominant lethality) after X-irradiation and relation to recessive lethals and translocations. Mutat Res. 1993;285:313-25 pubmed
    ..It is concluded that genetic damage recovered in a repair deficient background is likely to be qualitatively different even if the frequency of the damage induced by a given dose is not altered. ..
  27. Joyce E, McKim K. Chromosome axis defects induce a checkpoint-mediated delay and interchromosomal effect on crossing over during Drosophila meiosis. PLoS Genet. 2010;6: pubmed publisher
    ..These findings suggest a model in which the pachytene checkpoint monitors the structure of chromosome axes and may function to promote an optimal number of crossovers. ..
  28. Negishi T, Shiotani T, Fujikawa K, Hayatsu H. The genotoxicities of N-nitrosamines in Drosophila melanogaster in vivo: the correlation of mutagenicity in the wing spot test with the DNA damages detected by the DNA-repair test. Mutat Res. 1991;252:119-28 pubmed
    ..These Drosophila tests may be useful in predicting carcinogenic potentials of compounds. ..
  29. Miyamoto T. High frequency of spontaneous Minute mutations detected in the F1 progeny of interstrain matings between a recombination-defective mei-9L1 and the y w m f/sc8(y+) Y BS; dp strain of Drosophila melanogaster. Mutat Res. 1990;243:207-12 pubmed
  30. LaFave M, Andersen S, Stoffregen E, Holsclaw J, Kohl K, Overton L, et al. Sources and structures of mitotic crossovers that arise when BLM helicase is absent in Drosophila. Genetics. 2014;196:107-18 pubmed publisher
    ..These findings provide important new insights into sources and structures of mitotic crossovers and functions of BLM helicase. ..
  31. Olsen O, Green M. The mutagenic effects of diepoxybutane in wild-type and mutagen-sensitive mutants of Drosophila melanogaster. Mutat Res. 1982;92:107-15 pubmed
    ..By inference the same is also the case in females homozygous for 3 other mutagen-sensitive mutants. ..
  32. Gamo S, Megumi T, Nakashima Tanaka E. Sensitivity to ether anesthesia and to gamma-rays in mutagen-sensitive strains of Drosophila melanogaster. Mutat Res. 1990;235:9-13 pubmed
    ..These findings indicate that the targets for ether anesthesia, knock-down and lethality may be different. Lethality appears to be caused by DNA damage, while the other 2 endpoints appear not to be related to DNA damage. ..
  33. Mishra M, Sharma A, Negi M, Dwivedi U, Chowdhuri D. Tracing the tracks of genotoxicity by trivalent and hexavalent chromium in Drosophila melanogaster. Mutat Res. 2011;722:44-51 pubmed publisher
    ..The study suggests that both pre- and post-replication pathways are affected in Drosophila by Cr(VI) leading to genotoxicity, which may have consequences for metal-induced carcinogenesis. ..
  34. Voelker R, Greenleaf A, Gyurkovics H, Wisely G, Huang S, Searles L. Frequent Imprecise Excision among Reversions of a P Element-Caused Lethal Mutation in Drosophila. Genetics. 1984;107:279-94 pubmed
    ..We suggest that these excisions are by-products of, rather than intermediates in, the transposition process. ..
  35. Trowbridge K, McKim K, Brill S, Sekelsky J. Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis. Genetics. 2007;176:1993-2001 pubmed
    ..Lethality and elevated apoptosis were partially suppressed by a mutation in spn-A, which encodes the ortholog of the strand invasion protein Rad51. These findings provide insights into the causes of synthetic lethality. ..
  36. Carpenter A, Baker B. On the Control of the Distribution of Meiotic Exchange in DROSOPHILA MELANOGASTER. Genetics. 1982;101:81-9 pubmed
  37. Carpenter A. Recombination nodules and synaptonemal complex in recombination-defective females of Drosophila melanogaster. Chromosoma. 1979;75:259-92 pubmed
    ..It is suggested that all aspects of meiotic recombination are under the aegis of recombination nodules. ..
  38. Koana T, Tsujimura H. A U-shaped dose-response relationship between x radiation and sex-linked recessive lethal mutation in male germ cells of Drosophila. Radiat Res. 2010;174:46-51 pubmed publisher
    ..These results showed that DNA repair was responsible for the U-shaped dose-response relationship in Drosophila. ..
  39. Osgood C, Boyd J. Apurinic endonuclease from Drosophila melanogaster: reduced enzymatic activity in excision-deficient mutants of the mei-9 and mus(2)201 Loci. Mol Gen Genet. 1982;186:235-9 pubmed
    ..At least one allele of a second excision-deficient strain, cn mus (2)201D1, also shows reduced AP-endonuclease activity in ganglia extracts. ..
  40. Dusenbery R, McCormick S, Smith P. Drosophila mutations at the mei-9 and mus(2)201 loci which block excision of thymine dimers also block induction of unscheduled DNA synthesis by methyl methanesulfonate, ethyl methanesulfonate, N-methyl-N-nitrosourea, UV light and X-rays. Mutat Res. 1983;112:215-30 pubmed
    ..These data correlate well with the degree of larval hypersensitivity of the strains and suggest that mutations at both loci block the excision repair of a wide variety of DNA damage prior to the resynthesis step. ..
  41. Vogel E. Tests for recombinagens in somatic cells of Drosophila. Mutat Res. 1992;284:159-75 pubmed
  42. Pontecorvo G, Avitabile A, Esposito G, Migliaccio G, Carfagna M. Induced crossing-over in Drosophila melanogaster germ cells of DNA repair-proficient and repair-deficient (mei-9L1) males following larval feeding with 5-azacytidine and mitomycin C. Mutat Res. 1992;266:93-8 pubmed
    ..The apparently lower sensitivity of mei-9L1 males to crossing-over induction may be the result of an incomplete crossing-over process. ..
  43. Koana T, Okada M, Takashima Y, Ikehata M, Miyakoshi J. Involvement of eddy currents in the mutagenicity of ELF magnetic fields. Mutat Res. 2001;476:55-62 pubmed
    ..These results suggest that the detected mutagenic activity was that of the induced eddy current, rather than that of the magnetic field itself. ..
  44. Kuo H, McMahan S, Rota C, Kohl K, Sekelsky J. Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases. Genetics. 2014;198:935-45 pubmed publisher
    ..Since Fancm mutants can tolerate loss of a single resolvase, we were able to show that spontaneous mitotic crossovers that occur when FANCM is missing are dependent on MUS312 and either MUS81 or SLX1. ..
  45. Leonhardt E, Boyd J. Identification of a new locus, mus115, in Drosophila melanogaster. Mutat Res. 1993;301:121-4 pubmed
    ..This search has identified a new locus, mus115, through the recovery of a mutant that is strongly hypersensitive to nitrogen mustard but marginally sensitive to methyl methanesulfonate. ..
  46. Johnson Schlitz D, Flores C, Engels W. Multiple-pathway analysis of double-strand break repair mutations in Drosophila. PLoS Genet. 2007;3:e50 pubmed
  47. Sekelsky J, Brodsky M, Burtis K. DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol. 2000;150:F31-6 pubmed
  48. McKim K, Jang J, Sekelsky J, Laurencon A, Hawley R. mei-41 is required for precocious anaphase in Drosophila females. Chromosoma. 2000;109:44-9 pubmed
    ..The effect of mei-41 is dependent on double-strand break formation. Thus, in mutants that fail to initiate meiotic recombination the absence of mei-41 has no effect. ..
  49. Fujikawa K, Fort F, Samejima K, Sakamoto Y. Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test. Mutat Res. 1993;290:175-82 pubmed
    ..The Drosophila DNA repair assay will serve as a simple adjunct to the already available means for studying the genotoxic potency of aromatic amines and polycyclic aromatic hydrocarbons. ..
  50. Lankenau D, Gloor G. In vivo gap repair in Drosophila: a one-way street with many destinations. Bioessays. 1998;20:317-27 pubmed
    ..This review summarizes results that provide new insights into the process of gap repair in Drosophila and outline some recent experiments that demonstrate the power of the gene targeting technique. ..
  51. Banga S, Bloomquist B, Brodberg R, Pye Q, Larrivee D, Mason J, et al. Cytogenetic characterization of the 4BC region on the X chromosome of Drosophila melanogaster: localization of the mei-9, norpA and omb genes. Chromosoma. 1986;93:341-6 pubmed
    ..This cytogenetic localization of these loci will facilitate the cloning and molecular analysis of genes controlling a key function in DNA repair and recombination (mei-9), and two fundamental neural functions (norpA and omb). ..
  52. Banga S, Velazquez A, Boyd J. P transposition in Drosophila provides a new tool for analyzing postreplication repair and double-strand break repair. Mutat Res. 1991;255:79-88 pubmed
    ..1990). Involvement of the mei-41 and mus302 genes in the repair of P element-induced double-strand breaks and postreplication repair points to a commonality in the mechanisms of these processes. ..
  53. Varentsova E, Khromykh I. [Interaction of mutations of the genes for mutagen sensitivity mei-9, mei-41 and rad201 as affected by ionizing radiation]. Genetika. 1997;33:328-32 pubmed
    ..The maternal effect was demonstrated to be characteristic of all mutants tested even when larvae were exposed to radiation at a late stage of development. ..
  54. Smith P. Mutagen sensitivity of Drosophila melanogaster. III. X-linked loci governing sensitivity to methyl methanesulfonate. Mol Gen Genet. 1976;149:73-85 pubmed
    ..The continued isolation and characterization of conditional mutants of this type promises future insights into the mechanisms of DNA replication, DNA repair and recombination in this complex higher eucaryote. ..
  55. Rodriguez Arnaiz R, Romas Morales P, Zimmering S. Evaluation in Drosophila melanogaster of the mutagenic potential of furfural in the mei-9a test for chromosome loss in germ-line cells and the wing spot test for mutational activity in somatic cells. Mutat Res. 1992;280:75-80 pubmed
    ..Acute treatment of larvae was chosen as the method of exposure. Evidence indicates that furfural induces somatic damage as measured in the wing spot test. ..
  56. Graf U, Hall C, van Schaik N. On the use of excision repair defective cells in the wing somatic mutation and recombination test in Drosophila melanogaster. Environ Mol Mutagen. 1990;16:225-37 pubmed
    ..For these and other practical reasons the use of this specific cross is not recommended in the wing spot test for routine screening purposes. ..
  57. Houle J, Friedberg E. The Drosophila ortholog of the human XPG gene. Gene. 1999;234:353-60 pubmed
    ..One of these is unique to all four higher eukaryotic sequences. Conceivably this domain evolved to support the essential function of XPG protein. ..
  58. Morris J, Lehmann R. Drosophila oogenesis: versatile spn doctors. Curr Biol. 1999;9:R55-8 pubmed
    ..Genes of the spindle class, which encode double-strand break repair enzymes and RNA helicases, affect oocyte polarity and the decision whether to differentiate as an oocyte or a nurse cell. ..
  59. Meyer R, Delaage M, Rosset R, Capri M, Ait Ahmed O. A single mutation results in diploid gamete formation and parthenogenesis in a Drosophila yemanuclein-alpha meiosis I defective mutant. BMC Genet. 2010;11:104 pubmed publisher
    ..This work paves the way to further investigations on the evolution of the mechanisms that support sexual reproduction. ..
  60. Sarantseva S, Khromykh I. [Effect of gamma-irradiation on oogenesis of Drosophila mutants defective for reparation and meiotic recombination]. Genetika. 2001;37:770-8 pubmed
  61. Dusenbery R, Smith P. Cellular responses to DNA damage in Drosophila melanogaster. Mutat Res. 1996;364:133-45 pubmed
  62. Mishra M, Sharma A, Shukla A, Kumar R, Dwivedi U, Kar Chowdhuri D. Genotoxicity of dichlorvos in strains of Drosophila melanogaster defective in DNA repair. Mutat Res Genet Toxicol Environ Mutagen. 2014;766:35-41 pubmed publisher
    ..This study suggests involvement of both pre- and post-replication repair pathways against DDVP-induced DNA damage in Drosophila, with oxidative DNA damage leading to genotoxicity. ..
  63. Shaposhnikov M, Latkin D, Plyusnina E, Shilova L, Danilov A, Popov S, et al. The effects of pectins on life span and stress resistance in Drosophila melanogaster. Biogerontology. 2014;15:113-27 pubmed publisher
    ..These results indicate that the observed lifespan-extending effect of the LM pectins may be mediated by intracellular pathways that involve NF-?B signalling and activation of stress resistance genes. ..
  64. Gatti M. Genetic control of chromosome breakage and rejoining in Drosophila melanogaster: spontaneous chromosome aberrations in X-linked mutants defective in DNA metabolism. Proc Natl Acad Sci U S A. 1979;76:1377-81 pubmed
  65. Baker B, Carpenter A, Ripoll P. The Utilization during Mitotic Cell Division of Loci Controlling Meiotic Recombination and Disjunction in DROSOPHILA MELANOGASTER. Genetics. 1978;90:531-78 pubmed
    ..Mutants at the two remaining loci (nod, pal) do not affect mitotic chromosome stability. ..
  66. Sarantseva S, Khromykh I. [The interaction of the rad201 gene with mei-9 and mei-41 genes in germline cells of Drosophila female]. Genetika. 2001;37:926-9 pubmed
    ..The results obtained indicated that in intact and irradiated oocytes of double mutants mei-9a rad201G1 and mei-41D5 rad201G1, mutation rad201G1 epistatically suppresses the mutations of the both mei genes. ..
  67. de Buendía P. Search for DNA repair pathways in Drosophila melanogaster. Mutat Res. 1998;407:67-84 pubmed
    ..The following groups were found: (a) group of mei9 and mus201, analogous to RAD3, (b) group of mei41 and mus302 analogous to RAD52 and, (c) group of mus104 and mus101 ..
  68. Wei D, Rong Y. A genetic screen for DNA double-strand break repair mutations in Drosophila. Genetics. 2007;177:63-77 pubmed
  69. Yamamoto A, Brodberg R, Banga S, Boyd J, Mason J. Recovery and characterization of hybrid dysgenesis-induced mei-9 and mei-41 alleles of Drosophila melanogaster. Mutat Res. 1990;229:17-28 pubmed
    ..Hybrid dysgenesis-induced reversion of 2 mutants, mei-9RT1 and mei-41RT2, is associated with the loss of the P element from regions 4B and 14C respectively. ..
  70. Mason J, Green M, Shaw K, Boyd J. Genetic analysis of X-linked mutagen-sensitive mutants of Drosophila melanogaster. Mutat Res. 1981;81:329-43 pubmed
    ..Cytogenetically mus(1)101D1 is between salivary chromosome bands 12A6,7 and 12D3, mus(1)103D1 is between bands 12A1,2 and 12A6,7 and mus(1)109A1 is in section 8F3--9A2. ..
  71. Carpenter A. Mismatch repair, gene conversion, and crossing-over in two recombination-defective mutants of Drosophila melanogaster. Proc Natl Acad Sci U S A. 1982;79:5961-5 pubmed
    ..It is therefore likely, at least in Drosophila, that the isomerization step in Meselson-Radding type molecular models of recombination is under genetic control. ..