Gene Symbol: MED31
Description: Mediator complex subunit 31
Alias: BcDNA:GM28912, CG1057, Dmel\CG1057, Med31, Trap18, dSOH1, dTRAP18, med31, p36, mediator complex subunit 31, CG1057-PA, CG1057-PB, CG1057-PC, CG1057-PD, CG1057-PE, MED31-PA, MED31-PB, MED31-PC, MED31-PD, MED31-PE, mediator
Species: fruit fly
Bosveld F, van Hoek S, Sibon O. Establishment of cell fate during early Drosophila embryogenesis requires transcriptional Mediator subunit dMED31. Dev Biol. 2008;313:802-13 pubmed
..However, how this information is being transmitted is largely unknown. The transcriptional Mediator complex is involved in the fine tuning of the signaling between chromatin status, transcription factors and the ..
Park J, Werner J, Kim J, Lis J, Kim Y. Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock. Mol Cell. 2001;8:9-19 pubmed
..Here, we show that upon heat shock the Pol II-free form of Mediator is rapidly recruited to HSF binding sites...
Park J, Kim J, Kim L, Kim S, Kim Ha J, Kim J, et al
. Signal-induced transcriptional activation by Dif requires the dTRAP80 mediator module. Mol Cell Biol. 2003;23:1358-67 pubmed
The Mediator complex is the major multiprotein transcriptional coactivator complex in Drosophila melanogaster...
Andersen S, Kuo H, Savukoski D, Brodsky M, Sekelsky J. Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila. PLoS Genet. 2011;7:e1002315 pubmed publisher
..Our studies of synthetic lethality provide insights into the multiple functions of DmBLM and how various endonucleases may function when DmBLM is absent. ..
Tsubouchi A, Caldwell J, Tracey W. Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Curr Biol. 2012;22:2124-34 pubmed publisher
..These cells show physiological responses to force. Ion channels in several force-sensing gene families are required for behavioral sensitivity to touch and for the formation of the actin-rich sensory filopodia. ..
Oh H, Slattery M, Ma L, Crofts A, White K, Mann R, et al
. Genome-wide association of Yorkie with chromatin and chromatin-remodeling complexes. Cell Rep. 2013;3:309-18 pubmed publisher
..Coimmunoprecipitation and mass spectrometry identify GAGA factor (GAF), the Brahma complex, and the Mediator complex as Yorkie-associated nuclear protein complexes...
Homem C, Steinmann V, Burkard T, Jais A, Esterbauer H, Knoblich J. Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell. 2014;158:874-888 pubmed publisher
..Here, we show that changes in energy metabolism induced by the steroid hormone ecdysone and the Mediator initiate an irreversible cascade of events leading to cell-cycle exit in Drosophila neural stem cells...