Gene Symbol: matotopetli
Alias: CG8484, Dmel\CG8484, Topi, matotopetli, CG8484-PA, topi-PA
Species: fruit fly
Perezgasga L, Jiang J, Bolival B, Hiller M, Benson E, Fuller M, et al
. Regulation of transcription of meiotic cell cycle and terminal differentiation genes by the testis-specific Zn-finger protein matotopetli. Development. 2004;131:1691-702 pubmed
..We identify, clone and characterize a new aly-class meiotic arrest gene, matotopetli (topi), which encodes a testis-specific Zn-finger protein that physically interacts with Comr...
Hiller M, Chen X, Pringle M, Suchorolski M, Sancak Y, Viswanathan S, et al
. Testis-specific TAF homologs collaborate to control a tissue-specific transcription program. Development. 2004;131:5297-308 pubmed
Jiang J, Benson E, Bausek N, Doggett K, White Cooper H. Tombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early. Development. 2007;134:1549-59 pubmed
..The Drosophila aly-class meiotic-arrest loci (aly, comr, achi/vis and topi) are essential for activation of transcription of many differentiation-specific genes, and several genes important ..
Monk A, Siddall N, Volk T, Fraser B, Quinn L, McLaughlin E, et al
. HOW is required for stem cell maintenance in the Drosophila testis and for the onset of transit-amplifying divisions. Cell Stem Cell. 2010;6:348-60 pubmed publisher
..Spatiotemporal regulation of HOW expression is therefore required to specify the four spermatogonial transit-amplifying divisions. ..
Lu C, Kim J, Fuller M. The polyubiquitin gene Ubi-p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila. Development. 2013;140:3522-31 pubmed publisher
..Our results suggest a conserved role of polyubiquitin genes in male meiosis and a potential mechanism leading to meiosis I maturation arrest. ..
Beall E, Lewis P, Bell M, Rocha M, Jones D, Botchan M. Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. Genes Dev. 2007;21:904-19 pubmed
..Together, these data demonstrate that MMB serves diverse roles in different developmental pathways, and members of MMB can be found in alternative, noninteracting complexes in different cell types. ..
Di Cara F, Cavaliere D, Galliero V, Polito L, Digilio F. Expressional and functional analysis of the male-specific cluster mst36F during Drosophila spermatogenesis. Insect Mol Biol. 2010;19:807-13 pubmed publisher
..We obtained a reduction of fertility in the transgenic adult males compared to the wild type. These data suggest that the Mst36Fa and Mst36Fb proteins may have an important role in the production of functional sperm. ..
Lu C, Fuller M. Recruitment of Mediator Complex by Cell Type and Stage-Specific Factors Required for Tissue-Specific TAF Dependent Gene Activation in an Adult Stem Cell Lineage. PLoS Genet. 2015;11:e1005701 pubmed publisher
..The Mediator subunit Med22 binds the tMAC component Topi when the two are coexpressed in S2 cells, suggesting direct recruitment...
Zhao J, Klyne G, Benson E, Gudmannsdottir E, White Cooper H, Shotton D. FlyTED: the Drosophila Testis Gene Expression Database. Nucleic Acids Res. 2010;38:D710-5 pubmed publisher
..org/software/), and provides both web-based search and browse interfaces, and programmatic access via an SQL dump, OAI-PMH and SPARQL. FlyTED is available at http://www.fly-ted.org/. ..